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Fang H.-F.,Institute of Nuclear Energy Research of Taiwan
Renewable Energy | Year: 2014

The average wind speed and wind power density of Taiwan had been evaluated at 10m, 30m and 50m by simulation of mesoscale numerical weather prediction model (MM5). The results showed that wind energy potential of this area is excellent. Taiwan has offered funds to encourage the founding of offshore wind farms in this area. The purpose of this study is to make a high resolution wind energy assessment for the offshore area of Taiwan west coast and Penghu archipelago by using WAsP. The result of this study has been used to the relative financial planning of offshore wind farm projects in Taiwan. The basic inputs of WAsP include wind weather data and terrain data. The wind weather data was from a monitoring station located on a remote island, Tongi, because that all of weather stations in the area of Taiwan west coast are affected by urbanization. SRTM was selected to be used as terrain data and downloaded from CGIAR-CSI for voids problem. The coverage of considered terrain area in this assessment work is about 300km×400km that made some difficulties to run wind energy assessment of the whole area with a high resolution of 100m. So the interested area of this study is divided into 19 areas for the wind energy assessment and mapping. The assessment results show the Changhua area has best wind energy potential in the area of Taiwan west coast which power density is above 1000W/m2 height and the areas of Penghu archipelago are above 1300W. These results are higher than the expected from NWP. 180 of 3MW wind turbines were used in the study of micro sitting in the Changhua area.The type and number of the wind turbines and the layout of the wind farm is similar to the prior study of Taipower Company for demonstrating the reliability of this study. The assessment result of average net annual energy production (AEP) of the wind farm is about 11.3GWh that is very close to the prior study. The terrain effect is also studied. The average net annual energy production will decrease about 0.7GWh if the wind turbines were moved eastward 3600m closer to the coast because of terrain effect. As the same reason, the average net annual energy production would be increased to 11.392GWh if the wind farm is moved westward 3600m away from the coast. © 2013 Elsevier Ltd. Source

Tsai C.C.,Institute of Nuclear Energy Research of Taiwan
International journal of nanomedicine | Year: 2011

Nanoliposomes are designed as carriers capable of packaging drugs through passive targeting tumor sites by enhanced permeability and retention (EPR) effects. In the present study the biodistribution, pharmacokinetics, micro single-photon emission computed tomography (micro-SPECT/CT) image, dosimetry, and therapeutic efficacy of (188)Re-labeled nanoliposomes ((188)Re-liposomes) in a C26 colonic peritoneal carcinomatosis mouse model were evaluated. Colon carcinoma peritoneal metastatic BALB/c mice were intravenously administered (188)Re-liposomes. Biodistribution and micro-SPECT/CT imaging were performed to determine the drug profile and targeting efficiency of (188)Re-liposomes. Pharmacokinetics study was described by a noncompartmental model. The OLINDA|EXM computer program was used for the dosimetry evaluation. For therapeutic efficacy, the survival, tumor, and ascites inhibition of mice after treatment with (188)Re-liposomes and 5-fluorouracil (5-FU), respectively, were evaluated and compared. In biodistribution, the highest uptake of (188)Re-liposomes in tumor tissues (7.91% ± 2.02% of the injected dose per gram of tissue [%ID/g]) and a high tumor to muscle ratio (25.8 ± 6.1) were observed at 24 hours after intravenous administration. The pharmacokinetics of (188)Re-liposomes showed high circulation time and high bioavailability (mean residence time [MRT] = 19.2 hours, area under the curve [AUC] = 820.4%ID/g*h). Micro-SPECT/CT imaging of (188)Re-liposomes showed a high uptake and targeting in ascites, liver, spleen, and tumor. The results were correlated with images from autoradiography and biodistribution data. Dosimetry study revealed that the (188)Re-liposomes did not cause high absorbed doses in normal tissue but did in small tumors. Radiotherapeutics with (188)Re-liposomes provided better survival time (increased by 34.6% of life span; P < 0.05), tumor and ascites inhibition (decreased by 63.4% and 83.3% at 7 days after treatment; P < 0.05) in mice compared with chemotherapeutics of 5-fluorouracil (5-FU). The use of (188)Re-liposomes for passively targeted tumor therapy had greater therapeutic effect than the currently clinically applied chemotherapeutics drug 5-FU in a colonic peritoneal carcinomatosis mouse model. This result suggests that (188)Re-liposomes have potential benefit and are safe in treating peritoneal carcinomatasis of colon cancer. Source

Wu T.-Y.,Institute of Nuclear Energy Research of Taiwan
Engineering Structures | Year: 2013

The objective of this paper is to perform dynamic nonlinear analysis of shell structures using a vector intrinsic finite element (VFIFE). The procedures of VFIFE are designed to carry out a vector-mechanics-based theory, vector form analysis in which a fundamental concept called point value description is proposed. It enables VFIFE to deliberately treat the shell problems with large deflections, large overall motions and even fragmentations. The interaction forces amid particles are complemented by the generalized forces evaluated by a triangular element of VFIFE family recently developed using physical modeling procedures. In this paper, the problems with large overall motion, large deflection, nonlinear material property and contact/impact are further tested to justify the performance of the element on highly nonlinear analysis. It is reveals that the VFIFE element has good reliability and accuracy on solving shell problems with multiple nonlinearities. © 2013 Elsevier Ltd. Source

Ou T.-C.,Institute of Nuclear Energy Research of Taiwan
International Journal of Electrical Power and Energy Systems | Year: 2013

A direct building algorithm for microgrid distribution ground fault (MGDGF) analysis is proposed in this paper. Four possibilities of the network topology changes were considered with the proposed iterative process for ground fault analysis. This paper also discusses the ground fault model of a battery energy storage system (BESS) as a distributed energy resource (DER), which can be used for both islanded and grid-connected modes. The proposed algorithm is robust and accurate. Test results demonstrate the potential of the proposed algorithm in MGDGF applications. © 2013 Elsevier Ltd. All rights reserved. Source

Ou T.-C.,Institute of Nuclear Energy Research of Taiwan
International Journal of Electrical Power and Energy Systems | Year: 2012

A novel unsymmetrical faults analysis method with hybrid compensation for microgrid (MG) distribution systems is proposed. The method employs the actual three-phase models to handle unsymmetrical faults. Two matrices, which are built from the topological characteristics of MG distribution networks, and then combined with the proposed hybrid compensation method for injecting branch mismatch currents caused by the fault are used to analyze the branch mismatch currents and bus mismatch voltages directly. An unsymmetrical fault, with appropriate fault boundary conditions can be obtained. The proposed method can then be developed from these two matrices and be used to solve the various types of single or simultaneous unsymmetrical faults. This paper also discusses modeling of a microturbine generation (MTG) as a distributed generator (DG), which delivered for both islanded and grid-connected modes of operation. Test results show that the proposed method is efficient, accurate and easy to program for unsymmetrical faults analysis. © 2012 Elsevier Ltd. All rights reserved. Source

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