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PubMed | Center for Research in Environmental Epidemiology, CSIC - Institute of Environmental Assessment And Water Research, United States Center for Research in Environmental Epidemiology, National and Kapodistrian University of Athens and 4 more.
Type: Journal Article | Journal: Occupational and environmental medicine | Year: 2015

While several studies have reported associations of daily exposures to PM2.5 (particles less than 2.5m) with mortality, few studies have examined the impact of its constituents such as black carbon (BC), which is also a significant contributor to global climate change.We assessed the association between daily concentrations of BC and total, cardiovascular and respiratory mortality in two southern Mediterranean cities. Daily averages of BC were collected for 2years in Barcelona, Spain and Athens, Greece. We used case-crossover analysis and examined single and cumulative lags up to 3days.We observed associations between BC and all mortality measures. For a 3-day moving average, cardiovascular mortality increased by 4.5% (95% CI 0.7 to 8.5) and 2.0% (95% CI 0 to 4.0) for an interquartile change in BC in Athens and Barcelona, respectively. Considerably higher effects for respiratory mortality and for those above age 65 were observed. In addition, BC exhibited much greater toxicity per microgram than generic PM2.5.Our findings suggest that BC, derived in western industrialised nations primarily from diesel engines and biomass burning, poses a significant burden to public health, particularly in European cities with high-traffic density.

PubMed | Surgery Academy, Academy of Athens and Institute of Nuclear and Radiological science & Technology
Type: | Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging | Year: 2016

The Tera-Tomo 3D image reconstruction algorithm (a version of OSEM), provided with the Mediso nanoScan PC (PET8/2) small-animal positron emission tomograph (PET)/x-ray computed tomography (CT) scanner, has various parameter options such as total level of regularization, subsets, and iterations. Also, the acquisition time in PET plays an important role. This study aims to assess the performance of this new small-animal PET/CT scanner for different acquisition times and reconstruction parameters, for 2-deoxy-2-[Various image quality metrics were calculated for different realizations of [[A high regularization level at 52 iteration updates and 30min acquisition time were found to optimize most of the figures of merit investigated.

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