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Zimmermann E.,Institute of Neuroscience and Medicine | Bremmer F.,University of Marburg
Current Biology | Year: 2016

Our world appears stable, although our eyes constantly shift its image across the retina. What brain mechanisms allow for this perceptual stability? A recent study has brought us a step closer to answering this millennial question. © 2016 Elsevier Ltd. All rights reserved.

Zimmermann E.,Institute of Neuroscience and Medicine | Morrone M.C.,University of Pisa | Morrone M.C.,Scientific Institute Stella Maris IRCSS | Burr D.C.,University of Florence | Burr D.C.,CNR Institute of Neuroscience
Journal of Vision | Year: 2014

Visual objects presented around the time of saccadic eye movements are strongly mislocalized towards the saccadic target, a phenomenon known as ''saccadic compression.'' Here we show that perisaccadic compression is modulated by the presence of a visual saccadic target. When subjects saccaded to the center of the screen with no visible target, perisaccadic localization was more veridical than when tested with a target. Presenting a saccadic target sometime before saccade initiation was sufficient to induce mislocalization. When we systematically varied the onset of the saccade target, we found that it had to be presented around 100 ms before saccade execution to cause strong mislocalization: saccadic targets presented after this time caused progressively less mislocalization. When subjects made a saccade to screen center with a reference object placed at various positions, mislocalization was focused towards the position of the reference object. The results suggest that saccadic compression is a signature of a mechanism attempting to match objects seen before the saccade with those seen after. © 2014 ARVO.

Becker J.S.,Aeropharm GmbH | Pozebon D.,Federal University of Rio Grande do Sul | Matusch A.,Institute of Neuroscience and Medicine | Dressler V.L.,Federal University of Santa Maria | Becker J.S.,Julich Research Center
International Journal of Mass Spectrometry | Year: 2011

Assessing the inventory of biological systems in respect to metal species is a growing area of life science research called metallomics. Slugs are of special interest as monitor organisms for environmental contaminations. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was applied to map the distribution of total Zn in a section of a slug sample and to detect Zn-containing proteins after one-dimensional separation by gel electrophoresis (Blue Native PAGE). Interestingly, by far the largest fraction of protein bound Zn was explained by three sharp and prominent bands at 75, 100 and 150 kDa. Analysis of tryptic digests of selected bands using MALDI-TOF-MS and public databases failed to identify proteins within the Zn bands what may be due to coverage gaps concerning the species arion ater. Three non-Zn containing bands could be assigned to proteins known from other mollusc species. © 2011 Elsevier B.V.

Schilbach L.,University of Cologne | Timmermans B.,University of Aberdeen | Reddy V.,University of Portsmouth | Costall A.,University of Portsmouth | And 4 more authors.
Behavioral and Brain Sciences | Year: 2013

In spite of the remarkable progress made in the burgeoning field of social neuroscience, the neural mechanisms that underlie social encounters are only beginning to be studied and could - paradoxically - be seen as representing the dark matter of social neuroscience. Recent conceptual and empirical developments consistently indicate the need for investigations that allow the study of real-time social encounters in a truly interactive manner. This suggestion is based on the premise that social cognition is fundamentally different when we are in interaction with others rather than merely observing them. In this article, we outline the theoretical conception of a second-person approach to other minds and review evidence from neuroimaging, psychophysiological studies, and related fields to argue for the development of a second-person neuroscience, which will help neuroscience to really go social; this may also be relevant for our understanding of psychiatric disorders construed as disorders of social cognition. Copyright © 2013 Cambridge University Press.

Zimmermann E.,Institute of Neuroscience and Medicine | Fink G.,Institute of Neuroscience and Medicine | Fink G.,University of Cologne | Cavanagh P.,Attention
Journal of Vision | Year: 2013

We report a strong compression of space around a visual anchor presented in the near visual periphery (<5°). While subjects kept fixation, a salient visual stimulus (from now on referred to as "anchor") was presented, followed by a brief whole-field mask. At various times around mask onset a probe dot was flashed. Subjects estimated the position of the probe dot in relation to a subsequently presented comparison bar. The probe dot location was perceived nearly veridically when presented long before or after mask onset. However, when the probe dot was presented simultaneously with the mask it appeared shifted toward the anchor by as much as 50% of their separation. The anchor had to appear briefly before mask onset to attract the probe dot. No compression occurred when the anchor was presented long before or after the mask. When the probe dot and anchor were presented with similar brief duration, the more peripheral stimulus always shifted toward the more foveal stimulus independently of their temporal order. We hypothesize that the attraction might be explained by the summation of the neural activity distributions of probe and anchor. © 2013 ARVO.

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