Sahoo R.,Nilai University College |
Sahoo S.,Melaka Manipal Medical College |
Sahoo S.,PLNayak Institute of Nanobiotechnology |
Nayak P.L.,Plnayak Research Foundation
European Journal of Scientific Research | Year: 2011
In the present research program polycaprolactone was blended with gelatin at different proportions. This blend material was further blended with Cloisite 30 B to obtain the nanocomposites. The nanocomposites were blended with paclitaxel, an anti cancer drug, to study the in vitro drug delivery kinetics. The nanocomposites were characterized by using FTIR, SEM and XRD technique. The drug delivery kinetics was monitored at different pH medium and the kinetic parameters were evaluated. Based on the values of the kinetic parameters the mechanism of controlled drug delivery has been proposed.