Institute of Frontier Technology

andhra Pradesh, India

Institute of Frontier Technology

andhra Pradesh, India
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Viswanath K.,Indian Agricultural Research Institute | Viswanath K.,Institute of Frontier Technology | Sinha P.,Indian Agricultural Research Institute | Naresh Kumar S.,Indian Agricultural Research Institute | And 5 more authors.
Climatic Change | Year: 2017

Assessing disease risk has become an important component in the development of climate change adaptation strategies. Here, the infection ability of leaf blast (Magnaporthe oryzae) was modeled based on the epidemiological parameters of minimum (Tmin), optimum (Topt), and maximum (Tmax) temperatures for sporulation and lesion development. An infection ability response curve was used to assess the impact of rising temperature on the disease. The simulated spatial pattern of the infection ability index (IAI) corresponded with observed leaf blast occurrence in Indo-Gangetic plains (IGP). The IAI for leaf blast is projected to increase during the winter season (December–March) in 2020 (2010–2039) and 2050 (2040–2069) climate scenarios due to temperature rise, particularly in lower latitudes. However, during monsoon season (July–October), the IAI is projected to remain unchanged or even reduce across the IGP. The results show that the response curve may be successfully used to assess the impact of climate change on leaf blast in rice. The model could be further extended with a crop model to assess yield loss. © 2017 Springer Science+Business Media Dordrecht

Sudhamani H.,Sri Venkateswara University | Thaslim Basha S.K.,Sri Venkateswara University | Adam S.,Institute of Frontier Technology | Bhaskar B.V.,Sri Venkateswara University | Raju C.N.,Sri Venkateswara University
Monatshefte fur Chemie | Year: 2017

Abstract: On account of the antimicrobial activity of epinephrine, it is elegantly designed and synthesized in high yield a novel plethora of thiourea derivatives by treating with various biopotent isothiocyanates. The chemical structures of the new compounds were characterized by FT-IR, 1H, 13C NMR, LC–MS, and HR-MS and they have been evaluated for their in vitro antimicrobial and antioxidant activities (DPPH, FRAP, superoxide anion scavenging, and catalase activity). Nitro- and chloro-substituted compounds exhibited high antimicrobial activity. A molecular modeling study was performed on NADPH oxidase to investigate the hypothetical binding mode of the most active antioxidant agents and binding conformers were proposed. Graphical abstract: [Figure not available: see fulltext.] © 2017 Springer-Verlag Wien

Kumar M.S.,Sv Agricultural College | Devi R.S.J.,Sv Agricultural College | Reddy B.V.B.,Institute of frontier technology | Prasanthi L.,Institute of frontier technology
Legume Research | Year: 2017

In Andhra Pradesh, Chickpea is severely affected by wilt (Fusarium oxysporum f.sp. ciceri) and dry root rot (Rhizoctonia bataticola). In addition to these two diseases, Colletotrichum blight occurred in severe form during rabi 2009 and 2010 due to heavy unusual rains, which resulted in crop failure in many areas leading to re-sowing of the crops. Hence studies were conducted on Colletotrichum blight of chickpea, where a total of seven isolates were collected from major chickpea growing areas of Kurnool, Anantapur, Prakasam and Kadapa districts of Andhra Pradesh. The pathogen was isolated from infected plants and various morphological and cultural characteristics like size and shape of conidia, size of setae, chlamydospores, colony color, colony diameter, sectoring in the culture, mycelia dry weight and sporulation were studied and a great variability was observed among the isolates. © 2017, Agricultural Research Communication Centre. All rights reserved.

Sreekanth T.V.M.,Dongguk University | Nagajyothi P.C.,Dongguk University | Prasad T.N.V.K.V.,Institute of Frontier Technology | Duk Lee K.,Dongguk University
Current Nanoscience | Year: 2013

The present study deals with the green synthesis of silver nanoparticles (AgNPs) using Citrus reticulata juice as the reducing agent. The reaction carried out at room temperature (25°C) and at 55°C. The AgNPs were characterized by UV-Vis, TEM, XRD, AFM and FTIR measurements. The produced AgNPs were also evaluated for their increased antibacterial activities with tetracycline and penicillin against Gram-positive and Gram-negative bacteria. In this study, combination of AgNPs (at 55°C) and penicillin showed high inhibition zone in E. coli (18 mm) compared to that of AgNPs (at 25°C) and tetracycline. The cytotoxic effects of AgNPs from the Citrus reticulate juice on B16/ F10 melanoma cell line were evaluated by MTT (3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide) assay. MTT assay showed a minimum cell inhibition (14.83%) at 0.125 mM (AgNPs at 25°C) and a maximum cell inhibition (31.29%) was observed at 1 mM (AgNPs at 55°C). © 2013 Bentham Science Publishers.

Sudhamani H.,Andhra University | Thaslim Basha S.K.,Andhra University | Muni Chandra Reddy S.,Andhra University | Sreedhar B.,Vikrama Simhapuri University | And 2 more authors.
Research on Chemical Intermediates | Year: 2016

Abstract: Synthesis of a new series of sulfonamide and carbamate derivatives of 7-azaindole and evaluation of their anti-TMV and anti-oxidant activities are reported. Their chemical structures were characterized by IR, 1H and 13C NMR, mass and HRMS spectral analysis. The biological assay revealed that the compounds 4-nitrophenyl 1H-pyrrolo[2,3-b]pyridine-1-carboxylate (9g) and 4-nitrobenzyl 1H-pyrrolo[2,3-b]pyridine-1-carboxylate (9h) exhibited high inhibition against tobacco mosaic virus and abstraction of free radicals. Graphical Abstract: [Figure not available: see fulltext.] © 2016 Springer Science+Business Media Dordrecht

Sudhakar P.,Institute of Frontier Technology | Latha P.,Institute of Frontier Technology | Babu P.R.,Agricultural Research Station | Sujatha K.,Institute of Frontier Technology | Reddy K.R.,Institute of Frontier Technology
Indian Journal of Plant Physiology | Year: 2012

Global warming predicted to affect food security, especially rice, which is stable food crop as it is vulnerable to high temperature. In the present study, a novel temperature induction response (TIR) technique was adapted for identifying highly thermotolerant rice genotypes. This approach of TIR involves, first the identification of challenging temperature and induction temperature and later standardizing them before being used for screening the material for intrinsic stress tolerance. A lethal temperature of 55°C for 2 hours and induction treatment from 36°C-52°C for 5 hours was standardized in the laboratory. Using this standardized TIR protocol, highly thermotolerant rice genotypes were screened from 72 rice germplasm. Sufficient genotypic variability was noticed from zero level to 100% level of tolerance. Among the genotypes, NLR-145 showed highest thermotolerance in terms of 100 per cent seedlings survival and no reduction in root and shoot growth. NLR-40066, NLR-40070 and NLR-40050 also showed higher thermotolerance in terms of 90% seedlings survival and no reduction in root and shoot growth. This study revealed that TIR technique can be used for identification of thermotolerant rice genotypes. The identified rice varieties can be used as donor source for developing high temperature tolerant rice genotypes to withstand future temperature rise.

Sudhamani H.,Sri Venkateswara University | Thaslim Basha S.K.,Sri Venkateswara University | Adam S.,Institute of Frontier Technology | Madhusudhana S.,Sri Venkateswara University | And 2 more authors.
Research on Chemical Intermediates | Year: 2016

Abstract: A series of new urea and thiourea derivatives of lopinavir intermediate 7a–k was designed and synthesized from lopinavir intermediate by treating various biopotent isocyanates and isothiocyanates in the presence of base, 1,4-dimethyl piperazine, and their biological activity was evaluated . The bio-assay revealed that the compounds exhibited moderate to good antimicrobial and antioxidant activities; particularly, 7k showed high activity against Staphylococcus aureus. Further, to know the binding interactions of the title products with protease enzyme, molecular studies were performed, which revealed that 7j exhibited high binding affinity towards the enzyme cysteine protease from Staphylococcus aureus. The results from in vitro studies revealed that they can be used as effective antimicrobial and antioxidant agents. Furthermore, molecular docking studies shown very good interaction. Graphical Abstract: [Figure not available: see fulltext.] © 2016 Springer Science+Business Media Dordrecht

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