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Thao N.P.,Chungnam National University | Thao N.P.,Vietnam Academy of Science and Technology | Luyen B.T.T.,Chungnam National University | Luyen B.T.T.,Vietnam Academy of Science and Technology | And 12 more authors.
Archives of Pharmacal Research | Year: 2015

This study performed phytochemical and bioactive assessments of the mangrove Lumnitzera racemosa Willd. leaves. Bioassay-guided fractionation of the methanolic extracts led to the identification of thirty-six compounds (1-36), their structures were elucidated using detailed NMR spectroscopic and MS analysis. The extracts, fractions, and the isolated compounds were screened for potential antioxidant and cytotoxic activities. Antioxidant assays were performed using peroxyl radical-scavenging and reducing assays, whereas cytotoxicity was measured using MTT assays in HL-60 and Hel-299 cell lines. The methanolic extract, CH2Cl2 and n-BuOH fractions (10.0 μg/mL) exhibited potent antioxidant activity, with Trolox equivalent (TE) values of 24.94 ± 0.59, 28.34 ± 0.20, and 27.09 ± 0.37 (μM), respectively. In addition, the isolated compounds exerted cytotoxic effects in a dose-dependent manner; compounds 1 and 14 exhibited the most potent cytotoxicity in HL-60 cells, with IC50 values of 0.15 ± 0.29 and 0.60 ± 0.16 μM, respectively. To clarify the mechanism(s) behind these cytotoxic effects, we measured the time-dependent changes in apoptotic markers including the condensation and fragmentation of nuclear chromatin, and the downregulation of p-ERK1/2, p-AKT, and c-Myc levels. © 2014 The Pharmaceutical Society of Korea.


Van Du N.,Institute of Ecology and Biological Resources IEBR | Croat T.B.,Missouri Botanical Garden
Novon | Year: 2010

A new species, Typhonium vermiforme V. D. Nguyen & Croat (Araceae), is described from living materials collected from Quang Binh Province in central Vietnam. It is similar to T. bachmaense V. D. Nguyen & Hett. and T. trilobatum Schott, but differs from the first species by its much shorter spathe (ca. 9 cm long) and the distinctive, filiform and intertwining staminodes. It differs from the second species in having a solitary leaf and a pedate leaf blade. © 2010 Missouri Botanical Garden.


Nguyen A.D.,Institute of Ecology and Biological Resources IEBR
Zootaxa | Year: 2010

Pseudosundanina gen.nov. is created to accommodate the species Sundanina falcata Attems, 1937 new combination,which is redescribed from near-typotypic material. In addition, two new species of Sundanina are described: S. medialis sp.nov. from northern and S. cochinchina sp.nov. from southern Vietnam. A key is compiled to all four Sundaninini species currently known from Vietnam. Copyright © 2010 Magnolia Press.


PubMed | Institute of Ecology and Biological Resources IEBR
Type: | Journal: ZooKeys | Year: 2012

The first record of the genus Semia Matsumura (Cicadidae: Cicadinae, Cicadini) from Vietnam is presented. One new species, Semia spinosasp. n., is described from southern Vietnam. Photos of the adult, illustrations of the male genitalia, a distribution map and biological data are provided. A key to the species of Semia based on the male adults is also given.

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