Institute of Chemical Technology , formerly the University Department of Chemical Technology , is a premier chemical engineering research institute located in Mumbai, Maharashtra, India. It is focused on training and research in various branches of chemical engineering, chemical technology, and pharmacy. It was established in 1933 and was granted deemed university status in 2008. It is the only state-funded deemed university in India. Wikipedia.
Kapdi A.R.,Institute of Chemical Technology |
Fairlamb I.J.S.,University of York
Chemical Society Reviews | Year: 2014
Much success has been achieved with platinum-based chemotherapeutic agents, i.e. through interactions with DNA. The long-term application of Pt complexes is thwarted by issues, leading scientists to examine other metals such as palladium which could exhibit complementary modes of action (given emphasis wherever known). Over the last 10 years several research groups have focused on the application of an eclectic array of palladium complexes (of the type PdX2L2, palladacycles and related structures) as potential anti-cancer agents. This review therefore provides readers with an up to date account of the advances that have taken place over the past several decades. © 2014 The Royal Society of Chemistry.
Niakolas D.K.,Institute of Chemical Technology
Applied Catalysis A: General | Year: 2014
The present review is mainly dealing with the latest progress on sulfur poisoning of Solid Oxide Fuel Cell anodes, which in particular operate under reforming conditions. In general, sulfur seems to poison the electrochemical interface and at the same time or even faster blocks the catalytically active sites that are responsible for the H/C conversion, leading finally to the cells' degradation. Worldwide research effort has focused on the development of efficient and tolerant anode materials against carbon deposition and/or sulfur poisoning and one viable approach has been through targeted modifications of the traditional Ni-based anode cermets. In this respect, the review comprises a brief description of anode materials that are less prone to carbon deposition, but the main interest is focused on the studied sulfur tolerant cermets. The latter have been classified into four groups, depending on whether the examined anode feed comprises H2S in H2or H/Cs plus H2S fuels, while there is also discrimination between Ni-free and Nibased anode materials. Finally, the main part of the discussion focuses on the published studies regarding the effect of sulfur on the reforming activity and consequently on the electrochemical performance of H/C fueled Ni-based SOFCs. © 2014 Elsevier B.V. All rights reserved.
Torne S.,Institute of Chemical Technology
Pharmaceutical development and technology | Year: 2013
The purpose of the present study was to develop Tamoxifen loaded β-cyclodextrin nanosponges for oral drug delivery. The three types of Tamoxifen loaded β-cyclodextrin nanosponges were synthesized by varying the molar ratios of β-cyclodextrin to carbonyldiimidazole as a crosslinker viz. 1:2, 1:4 and 1:8. The Tamoxifen nanosponge complex (TNC) with particle size of 400-600 nm was obtained by freeze drying method. Differential scanning calorimetry, Fourier transformed infra-red spectroscopy and X-ray powder diffraction studies confirmed the complexation of Tamoxifen with cyclodextrin nanosponge. AUC and Cmax of TNC formulation (1236.4 ± 16.12 μg · mL(-1) h, 421.156 ± 0.91 μg/mL) after gastric intubation were 1.44 fold and 1.38 fold higher than plain drug (856.079 ± 15.18 μg · mL(-1) h, 298.532 ± 1.15 μg/mL). Cytotoxic studies on MCF-7 cells showed that TNC formulation was more cytotoxic than plain Tamoxifen after 24 and 48 h of incubation.
Zhou A.-N.,Institute of Chemical Technology
Computers and Geotechnics | Year: 2013
Hysteresis is common in soil-water phenomena, and the soil-water retention relationship is not a one-to-one relationship between the effective degree of saturation and the matric suction. Existing theoretical soil-water retention models are usually derived by applying a capillary law that does not depend on the contact angle to the cumulative distribution function of soil pores. These theoretical models usually contain equations only for the main drying and wetting branches, so additional empirical scanning laws are needed to model hysteresis behaviour between these branches. This paper proposes a contact angle-dependent model in incremental form to reproduce soil-water hysteresis behaviour. The change in suction during scanning wetting and drying processes leads to a change in both the effective degree of saturation and the liquid-solid contact angle. An allocation proportion function is proposed to divide suction increments into two parts, one of which is allocated to the change in the effective degree of saturation and the other consumed by changing the contact angle. The proposed hysteresis model contains only four parameters that can be conveniently calibrated by the main drying branch and a scanning wetting curve. Test results are included to validate the proposed hysteresis model. © 2012 Elsevier Ltd.
Gogate P.R.,Institute of Chemical Technology
Food and Bioprocess Technology | Year: 2011
Hydrodynamic cavitation, which was and is still looked upon as an unavoidable nuisance in the flow systems, can be a serious contender as an alternative to acoustic cavitation for intensification of different physical and chemical processing applications. Hydrodynamic cavitation results in the generation of hot spots, highly reactive free radicals and turbulence associated with liquid circulation currents, which can result in the intensification of various physical/chemical operations. The present work highlights the different aspects of hydrodynamic cavitation including the basic mechanism, bubble dynamics analysis with recommendations for optimum operating parameters, reactor designs and an overview of applications in different areas of food and water processing. The major applications discussed in the work include food sterilization, microbial cell disruption for the release or extraction of enzymes, water disinfection and wastewater treatment. It appears that hydrodynamic cavitation results in conditions similar to those generated using acoustic cavitation but at comparatively much larger scale of operation and with better energy efficiencies. © 2010 Springer Science + Business Media, LLC.