Albu M.G.,INCDTP Leather and Footwear Research Institute |
Titorencu I.,Nicolae Simionescu Institute of Biology and Cellular Pathology
Leather and Footwear Journal | Year: 2011
Peripheral nerve lesions are the cause of many lifelong disabilities, although peripheral nerves have self-regeneration capacity for less severe lesions. The paper presents nerve conductors developed based on collagen, with well-established properties and dimensions as required by peripheral nerve regeneration. These new materials have a native fibrillar structure of collagen; they are resistant to temperature, enzymatic degradation; they have a uniform microporous structure with pores of 5-20 μn, internal diameter of 1.3 mm and are biocompatible with neural cells. The paper also presents the results of the biocompatibility study of collagen nerve conductors.