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Kurimoto S.-I.,Tokushima University | Suzuki K.,Tokushima University | Okasaka M.,Tokushima University | Kashiwada Y.,Tokushima University | And 2 more authors.
Chemical and Pharmaceutical Bulletin | Year: 2012

Seven new sesquiterpene lactone glycosides (1-7) were isolated from the H20-soluble fraction from the MeOH extract of the roots of Ferula varia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configurations of compounds 1 and 2 were determined by modified Mosher's method. © 2012 The Pharmaceutical Society of Japan. Source


Kurimoto S.-I.,Tokushima University | Okasaka M.,Tokushima University | Kashiwada Y.,Tokushima University | Kodzhimatov O.K.,Institute of Botany and Botanical Garden | Takaishi Y.,Tokushima University
Journal of Natural Medicines | Year: 2011

As part of our chemical studies on the medical plants in Uzbekistan aimed at searching for new drug leads, we have examined the aerial parts of Mediasia macrophylla. This has resulted in the isolation of four new glucosides, together with 30 known compounds. The structures of new compounds were elucidated as (1′S)-(4-hydroxyphenyl) ethane-1′,2′-diol 2′-O-β- glucopyranoside (1), 3-(4′-methoxyphenyl)-propanol 1-O-β- glucopyranoside (2), 2-methoxy-3-hydroxy-5-(E)-propenyl-phenol 1-O-β-glucopyranoside (3), 1-O-angeloyl-β-glucopyranose (4), on the basis of spectral analysis. © 2010 The Japanese Society of Pharmacognosy and Springer. Source


Kurimoto S.-I.,Tokushima University | Suzuki K.,Tokushima University | Okasaka M.,Tokushima University | Kashiwada Y.,Tokushima University | And 2 more authors.
Phytochemistry Letters | Year: 2012

Five new eudesmane- (1-5), two new guaiane- (6 and 7) and one new germacrane-type (8) sesquiterpene lactone glucosides were isolated from the H2O-soluble fraction of the roots of Ferula varia. Their structures were elucidated by extensive spectroscopic analyses. The absolute configuration of 1 was determined by modified Mosher's method. © 2012 Phytochemical Society of Europe. Source


Kurimoto S.-i.,Tokushima University | Okasaka M.,Tokushima University | Kashiwada Y.,Tokushima University | Kodzhimatov O.K.,Institute of Botany and Botanical Garden | Takaishi Y.,Tokushima University
Phytochemistry | Year: 2010

Polyacetylenic glucosides (1-5) were isolated from the MeOH extract of Mediasia macrophylla, and their structures were established by spectroscopic analyses. Compounds 2-4 were the first examples of C10-polyacetylenic glucosides found in the family Umbelliferae, while compound 1 was a unique polyacetylenic glucoside possessing an α-pyrone moiety. © 2009 Elsevier Ltd. All rights reserved. Source

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