Shen S.,Institute of Biotechnology of Qinghai Academy of Agriculture and Forestry |
Shen S.,Tibet Plateau Biotechnology Key Laboratory of Ministry of Education |
Li W.,Tibet Plateau Biotechnology Key Laboratory of Ministry of Education |
Li W.,Institute of Plant Protection of Qinghai Academy of Agriculture and Forestry |
And 2 more authors.
Natural Product Research
A new compound 2-(4-hydroxybenzoyl) quinazolin-4(3H)-one (1) and four known compounds were isolated from a marine fungus Penicillium oxalicum 0312F1. The structure of the new compound 1 was elucidated based on the spectroscopic analysis. Bioactivity assays showed that 2-(4-hydroxybenzyl) quinazolin-4(3H)-one (2) and methyl 4-hydroxyphenylacetate (5) had potent inhibitory activity against tobacco mosaic virus (TMV), and the new compound 1 had moderate inhibitory activity against TMV and human gastric cancer cell SGC-7901. © 2013 © 2013 Taylor & Francis. Source
Wang F.,Institute of Biotechnology of Qinghai Academy of Agriculture and Forestry |
Wang F.,The Qinghai Tibet Plateau Biotechnology Key Laboratory of Ministry of Education |
Wang F.,Germplasm Innovation and Utilization of Plateau Crop Key Laboratory of Qinghai Province |
Li F.-D.,Tianshui Institute of Agricultural science |
And 3 more authors.
The genetic diversity of 123 potato clones, consisting of 103 clonal accessions from the International Potato Center (CIP) and 20 Chinese cultivars, was assessed using amplified fragment length polymorphism (AFLP) markers. Ten polymorphic primer combinations were selected to analyse and compare the diversity of the two sources of clones. A total of 521 reproducible bands were amplified, of which 488 were polymorphic. These AFLP markers were analysed to estimate the genetic distance (GD) and genetic similarity (GS) coefficient of all clones. The GD between pairs of clones ranged from 0.03 to 0.48. Nei's gene diversity index was between 0.236 and 0.387, with an average of 0.330. The index of Shannon's information varied from 0.361 to 0.567 with an average of 0.498. A high degree of polymorphism was observed with an average of 93.6% loci found to be polymorphic. Cluster analysis showed that the CIP accessions were grouped together at the GS 0.59 clustering line, whereas most Chinese cultivars grouped at the GS 0.82 clustering line. The diversity in CIP potato resources was found to be higher than that of the Chinese cultivars, indicating that the genetic base of Chinese potato cultivars is narrow and may benefit from broadening. © 2013 EAPR. Source