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Porta S.,Institute of Applied Stress Research | Porta S.,Medical University of Graz | Gell H.,Theresianische Militarakademie | Sadjak K.A.,Medical University of Graz | And 2 more authors.
Trace Elements and Electrolytes | Year: 2012

Mg++ blood concentrations were determined before and after a standard exercise of 80 watts and 8 minutes from 306, mainly male probands, which were subdivided into three groups: Group 1 consisted of probands with Mg++ concentrations of 0.45 mM/l and lower, Group 2 of those with Mg++ concentrations between 0.45 mM/l and 0.5 mM/l and Group 3 of probands with Mg values above 0.5 mM Mg/l. It turned out that in groups with lower Mg++ concentrations there was also a higher blood glucose, higher lactate, lower pH and lower buffer capacity, sometimes even before exercise. If hypomagnesemia is to be defined by concomitant worsening of the metabolism, the so called hypomagnesiemic threshold should be increased from 0.45 mM/l to 0.5 mM/l, nearly a third of the physiological range. ©2012 Dustri-Verlag Dr. K. Feistle. Source


Porta S.,Institute of Applied Stress Research | Porta S.,Medical University of Graz | Kisters K.,St. Anna Hospital | Korisek G.,Rehabilitation Clinique | And 2 more authors.
Trace Elements and Electrolytes | Year: 2011

Out of 100 microliters of capillary blood of 32 normotonic and 55 hypertonic (RR at least 140/100) diabetic patients, the following parameters were determined at 09:00 a.m.: pH, pCO2, baseexcess, HCO3, pO2, O2sat., Na, Ca, Mg, K, lactate and blood glucose. Group averages of the normotonic and hypertonic patients did not show any significant differences in the parameters mentioned. But when we split the 2 groups along their glucose averages, forming 4 subgroups with higher and lower glucose levels, significant differences between Mg and K in the respective groups were evident, pointing towards an increase in electrolyte metabolism due to both hyperglycemia and hypertonia. Linear regressions between Mg, glucose and pH within the four groups increased circumstantial evidence for our supposition of increased electrolyte metabolism being attributable to both hyperglycemia and hypertonia, considerably. It turned out that high blood glucose alone already increases electrolyte metabolism, shown by positive correlations with Mg and glucose and negative correlations between Mg and pH which culminates in the highest Mg values along with highest glucose and lowest pH values in patients with combined hyperglycemia and hypertonia. Although we partly drew similar conclusions in a former paper [14], the step forward in the present work is that results won by comparison of parameter changing (delta values) between two sampling events can be confirmed by using the directly determined data of just a single sample. Thus, appropriately processed data and comparatively simple mathematical operations like implementation of linear regressions do not only detect significant differences hidden behind similar group averages, but also considerably curtail the necessary diagnostic blood sampling. ©2011 Dustri-Verlag Dr. K. Feistle. Source


Porta S.,Institute of Applied Stress Research | Porta S.,Medical University of Graz | Gell H.,Theresianische Militarakademie | Pichlkastner K.,Theresianische Militarakademie | And 4 more authors.
Trace Elements and Electrolytes | Year: 2013

Out of 100 μ l of capillary blood of 15 ensigns of the Theresianische Militärakademie, ionized magnesium, ionized potassium, ionized calcium pH, basexcess, pCO2 and HCO3 were determined with a CCX device (NOVA Biomedical, Vienna, Austria) and CSA Software (PLK, Judendorf- Strassengel, Austria), before and after a 2,400-m run, and before and after an 8-week supplementation of 300 mg Magnesium per day. It turned out that neither averages of the ionized Mg levels in blood [5] nor those of the concomitantly determined metabolic parameters changed progressively with the duration of supplementation. However, correlative analyses did show that a progressive amelioration of the efficacy of metabolic reactions went along with advancing substitution time. Born out of significantly increasing metabolic efficacy, roughly three groups of Mg replenishment could be ascertained: Small Mg response along with low metabolic efficiency characterized an un-substituted low Mg state, ample Mg response along with fairly efficient metabolism characterized tolerable Mg replenishment, small Mg response along with highly efficient metabolism stood for an optimal Mg state. The gradual proceeding through those conditions takes both time and continuous replenishment. © 2013 Dustri-Verlag Dr. K. Feistle. Source


Stossier H.,Rehabilitation Clinic | Porta S.,Institute of Applied Stress Research | Porta S.,Medical University of Graz | Gell H.,Theresianische Militrakademie | And 2 more authors.
Trace Elements and Electrolytes | Year: 2013

The staff of a rehabilitation clinic was treated with an antioxidative nutraceutical during a demanding time of 8 weeks in a double blind, placebo controlled manner. Metabolic changes in metabolism and electrolyte state due to chronic workload, acute, standardized ergometry and, eventually to antioxidant treatment were recorded by capillary blood determination of pH, pCO>2>, BE, blood glucose, lactate, K, Ca, Mg by Clinical Stress Assessment software. It turned out that those parameters changed significantly after 8 weeks of increased workload and also after standard ergometry. However, the antioxidant treated group showed significantly less chronic signs of metabolic distress due to the demanding working situation as well as a significantly calmer reaction to acute ergometric load, concerning lactate, base excess and pCO>2> changes. Electrolyte changes figure prominently among the workload effects both in group averages and in treatment dependent correlations with metabolic data. Mg changes are particularly sensible to a rise in metabolic dynamics, and therefore Mg is liable to be substituted to grant undisturbed energy turnover in a difficult situation.the oxidative state of a person correlates linearly with concentrations of electrolytes and metabolic markers like pCO> 2>, base excess, lactate and blood glucose. © 2013 Dustri-Verlag Dr. K. Feistle. Source


Porta S.,Institute of Applied Stress Research | Porta S.,Medical University of Graz | Pichlkastner K.,Theresianische Militarakademie | Gell H.,Theresianische Militarakademie | And 3 more authors.
Trace Elements and Electrolytes | Year: 2010

Out of 100 μl of capillary blood of 28 ensigns of the Theresianische Militärakademie ionized Mg, ionized potassium, pH and basexcess, pCO 2 and HCO3 was determined with a CCX device (NOVA Biomedical) and CSASoftware (PLK, Judendorf - Strassengel, AUSTRIA). 14 ensigns had to perform a military steeplechase (obstacle race), already partly reported earlier [1], the other 14 participants absolved a combined sports activity consisting of running and swimming contests. Blood sampling and determination was done before and after the performance in both groups. Also both groups showed a highly significant negative correlation between pH and Kbefore sports, while at the same time pH/Mg correlation were positive before steeplechase and negative before combined sports. Negative pH/Mg correlations are mostly consistent with already agitated situations, which, in the case of combined sports was indeed the case because about 30 minutes of shivering due to a sharp fall in temperature was evident. Correlations with K and awarded scores showed that in the shivering group the participants with relatively highest K and lowest pH basally had the best chances for high scoring, while in the much less agitated first group the reaction was opposite. Thus, by correlative characterizing basal situations appropriate steps can be taken in time. The same correlation characterizes the ranking of each single participant within the peculiar situation of the group. This ranking seems to be connected with their chances of scoring in the subsequent sports. Moreover, possible outliers can be identified before performance or deployment. ©2010 Dustri-Verlag Dr. K. Feistle. Source

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