Time filter

Source Type

Feng X.,Institute of Advanced Materials | Zhang Y.,Institute of Advanced Materials | Zhou J.,Institute of Advanced Materials | Li Y.,Institute of Advanced Materials | And 5 more authors.
Nanoscale | Year: 2015

Three-dimensional nitrogen-doped graphene (3D N-doped graphene) was prepared through chemical vapor deposition (CVD) by using porous nickel foam as a substrate. As a model, a dopamine biosensor was constructed based on the 3D N-doped graphene porous foam. Electrochemical experiments exhibited that this biosensor had a remarkable detection ability with a wide linear detection range from 3 × 10-6 M to 1 × 10-4 M and a low detection limit of 1 nM. Moreover, the fabricated biosensor also showed an excellent anti-interference ability, reproducibility, and stability. © The Royal Society of Chemistry 2015.


Feng X.,Institute of Advanced Materials | Zhang Y.,Institute of Advanced Materials | Li Y.,Institute of Advanced Materials | Huang Z.,Institute of Advanced Materials | And 5 more authors.
Chemistry Letters | Year: 2015

Graphene-based micromotors with an alveolate surface of MnO2 hydrogen peroxide propelled are described. The micromotors display powerful propulsion in a low fuel level (2.5%), with a speed of over 111 μms-1, as well as efficient locomotion in biological media such as bovine serum. It has a good motion even in very low levels of the hydrogen peroxide fuel (down to 0.15%), which can compare favorably with Pt. The attractive properties of these new chemical-prepared micromotors hold great promise for biomedical applications. © 2015 The Chemical Society of Japan.


Feng X.,Institute of Advanced Materials | Zhou J.,Institute of Advanced Materials | Wang L.,Institute of Advanced Materials | Li Y.,Institute of Advanced Materials | And 4 more authors.
New Journal of Chemistry | Year: 2015

Flowerlike and polyhedral NiO-graphene nanocomposites have been successfully synthesized using a facile hydrothermal method. The formation mechanism of the two nanocomposites with different morphologies has been studied. The resulting products are characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopic analysis (XPS), thermogravimetry (TG), and the Brunauer-Emmett-Teller (BET) method. The prepared NiO-graphene nanocomposites with different shapes can be used for supercapacitor electrode materials. Through electrochemical tests, the flowerlike NiO-graphene composite shows higher specific capacitance than that of the polyhedral one with a specific capacitance as high as 500 F g-1 at a scan rate of 5 mV s-1 while the polyhedral NiO-graphene composite delivers better long-term cycle stability with 84% specific capacitance remaining after 3000 cycles in a 1 M KOH electrolyte. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2015.


PubMed | Institute of Advanced Materials and New York Medical College
Type: | Journal: Journal of the American Society of Nephrology : JASN | Year: 2016

The innate immune system has been implicated in both AKI and CKD. Damaged mitochondria release danger molecules, such as reactive oxygen species, DNA, and cardiolipin, which can cause NLRP3 inflammasome activation and upregulation of IL-18 and IL-1 It is not known if mitochondrial damage persists long after ischemia to sustain chronic inflammasome activation. We conducted a 9-month study in Sprague-Dawley rats after 45 minutes of bilateral renal ischemia. We detected glomerular and peritubular capillary rarefaction, macrophage infiltration, and fibrosis at 1 month. Transmission electron microscopy revealed mitochondrial degeneration, mitophagy, and deformed foot processes in podocytes. These changes progressed over the study period, with a persistent increase in renal cortical expression of IL-18, IL-1, and TGF-, despite a gradual decline in TNF- expression and macrophage infiltration. Treatment with a mitoprotective agent (SS-31; elamipretide) for 6 weeks, starting 1 month after ischemia, preserved mitochondrial integrity, ameliorated expression levels of all inflammatory markers, restored glomerular capillaries and podocyte structure, and arrested glomerulosclerosis and interstitial fibrosis. Further, helium ion microscopy vividly demonstrated the restoration of podocyte structure by SS-31. The protection by SS-31 was sustained for 6 months after treatment ended, with normalization of IL-18 and IL-1 expression. These results support a role for mitochondrial damage in inflammasome activation and CKD and suggest mitochondrial protection as a novel therapeutic approach that can arrest the progression of CKD. Notably, SS-31 is effective when given long after AKI and provides persistent protection after termination of drug treatment.


Deng J.,Hong Kong Baptist University | Deng J.,South China University of Technology | Fu J.,Hong Kong Baptist University | Ng J.,Hong Kong Baptist University | And 6 more authors.
Nanoscale | Year: 2016

The engineering of the chiroptical activity of the emerging chiral metamaterial, metallic nanospirals, is in its infancy. We utilize glancing angle deposition (GLAD) to facilely sculpture the helical structure of silver nanospirals (AgNSs), so that the scope of chiroptical engineering factors is broadened to include the spiral growth of homochiral AgNSs, the combination of left- and right-handed helical chirality to create heterochiral AgNSs, and the coil-axis alignment of the heterochiral AgNSs. It leads to flexible control over the chiroptical activity of AgNS arrays with respect to the sign, resonance wavelength and amplitude of circular dichroism (CD) in the UV and visible regime. The UV chiroptical mode has a distinct response from the visible mode. Finite element simulation together with LC circuit theory illustrates that the UV irradiation is mainly adsorbed in the metal and the visible is preferentially scattered by the AgNSs, accounting for the wavelength-related chiroptical distinction. This work contributes to broadening the horizons in understanding and engineering chiroptical responses, primarily desired for developing a wide range of potential chiroplasmonic applications. © The Royal Society of Chemistry 2016.


Varelas G.,Institute of Advanced Materials | Salifoglou A.,Aristotle University of Thessaloniki | Psycharis V.,Institute of Advanced Materials
Acta Crystallographica Section C: Crystal Structure Communications | Year: 2013

The structure of the title centrosymmetric compound, [Zn(C9H6NO)2(H2O)2], has already been solved three times [Merritt, Cady & Mundy (1954). Acta Cryst. 7, 473-476; Palenik (1964). Acta Cryst. 17, 696-700; Chen, Zhang, Shi, Huang, Liang & Zhou (2003). Acta Cryst. E59, m814-m815]. The authors of the two most recent papers state that they attained lower R1 values than that obtained in the 1954 paper, but they do not mention that Merritt et al. had derived the structural model from a twinned crystal. Also, from a structural point of view, there are strong indications that the most recent report is in fact the isostructural CuII complex already reported by Okabe & Saishu [Acta Cryst. (2001), E57, m251-m252] and not the ZnII complex. The structure of the title compound is reported here based on data obtained from a twinned crystal. © 2013 International Union of Crystallography.


Elyassi B.,University of Minnesota | Wahedi Y.A.,University of Minnesota | Wahedi Y.A.,The Petroleum Institute | Rajabbeigi N.,University of Minnesota | And 9 more authors.
Microporous and Mesoporous Materials | Year: 2014

Spatially well-distributed copper-zinc oxides supported on mesoporous silica (SBA-15 and commercial silica gel) showed high adsorption capacity for hydrogen sulfide (as high as 80 mgS/gsorbent) and stability during cyclic adsorption-regeneration process.© 2014 Elsevier Inc. All rights reserved.


Deng J.,Hong Kong Baptist University | Huang Z.,Hong Kong Baptist University | Huang Z.,Institute of Advanced Materials | Huang Z.,South China University of Technology
RSC Advances | Year: 2016

There is a lack of analytical approaches to study chiroptical activity of chiral nanoplasmons. Herein, LC circuit theory is proposed to analyze the chiroptical activity of heterojunction nanospirals, revealing the main contribution to be from radiative loss. Furthermore, chiral nanoplasmonic flexible thin films exhibit excellent mechanical stability of their chiroptical activity, paving the way to develop flexible/wearable optoelectronic devices integrated with chiral nanoplasmonics. © 2016 The Royal Society of Chemistry.


Liu J.,Hong Kong Baptist University | Huang Z.,Hong Kong Baptist University | Huang Z.,Institute of Advanced Materials | Huang Z.,Partner State Key Laboratory of Environmental and Biological Analysis | Huang Z.,South China University of Technology
Nanotechnology | Year: 2015

Engineering the porosity of silicon nanowires (SiNWs) is of fundamental importance, and this work introduces a new method for doing so. Metal-assisted chemical etching (MACE) of heavily doped Si(100) creates mesoporous silicon nanowires (mp-SiNWs). mp-SiNWs are transferred from the MACE-treated wafer to a sticky tape, leaving residues composed of broken mp-SiNWs and a mesoporous Si layer on the wafer. Then the taped wafer is re-treated by MACE, without changing the etching conditions. The second MACE treatment generates mp-SiNWs that are less porous and longer than those generated by the first MACE treatment, which can be attributed to the difference in the surface topography at the beginning of the etching process. Less porous mp-SiNWs reduce optical scattering from the porous Si skeletons, and vertically protrude on the wafer without aggregation to facilitate optical trapping. Consequently, less porous mp-SiNWs effectively reduce ultraviolet-visible reflection loss. © 2015 IOP Publishing Ltd.


Zhang Y.,Institute of Advanced Materials | Shen J.,Institute of Advanced Materials | Li H.,Institute of Advanced Materials | Wang L.,Institute of Advanced Materials | And 4 more authors.
Chemical Record | Year: 2016

The detailed records and conclusions on the important advancements in graphene-based electrochemical biosensors have been reviewed. Due to their outstanding properties, graphene-based materials have been widely studied for the accurate electrochemical detection of many biomolecules, which is extremely vital to the development of biomedical instruments, clinical diagnosis, and disease treatment. This review discusses the graphene research for the effective immobilization of enzymes, including glucose oxidase, horseradish peroxidase, and hemoglobin, etc., and the accurate detection of biomolecules, including glucose, hydrogen peroxide, dopamine, ascorbic acid, uric acid, nicotinamide adenine dinucleotide, DNA, RNA, and carcinoembryonic antigen, etc. In most of the cases, the graphene-based biosensors exhibited remarkable performance with high sensitivities, wide linear detection ranges, low detection limits, and long-term stabilities. © 2015 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Loading Institute of Advanced Materials collaborators
Loading Institute of Advanced Materials collaborators