Institute of Advanced Materials

Athens, Greece

Institute of Advanced Materials

Athens, Greece
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Parlak O.,Stanford University | Parlak O.,Linköping University | Kumar Mishra Y.,University of Kiel | Grigoriev A.,Uppsala University | And 10 more authors.
Nano Energy | Year: 2017

A great deal of interest has been paid to the application of carbon-based nano- and microstructured materials as electrodes due to their relatively low-cost production, abundance, large surface area, high chemical stability, wide operating temperature range, and ease of processing including many more excellent features. The nanostructured carbon materials usually offer various micro-textures due to their varying degrees of graphitisation, a rich variety in terms of dimensionality as well as morphologies, extremely large surface accessibility and high electrical conductivity, etc. The possibilities of activating them by chemical and physical methods allow these materials to be produced with further higher surface area and controlled distribution of pores from nanoscale upto macroscopic dimensions, which actually play the most crucial role towards construction of the efficient electrode/electrolyte interfaces for capacitive processes in energy storage applications. Development of new carbon materials with extremely high surface areas could exhibit significant potential in this context and motivated by this in present work, we report for the first time the utilization of ultralight and extremely porous nano-microtubular Aerographite tetrapodal network as a functional interface to probe the electrochemical properties for capacitive energy storage. A simple and robust electrode fabrication strategy based on surface functionalized Aerographite with optimum porosity leads to significantly high specific capacitance (640 F/g) with high energy (14.2 Wh/kg) and power densities (9.67×103 W/kg) which has been discussed in detail. © 2017


Song J.,Institute of Advanced Materials | Li H.,Institute of Advanced Materials | Li S.,Institute of Advanced Materials | Zhu H.,Institute of Advanced Materials | And 4 more authors.
New Journal of Chemistry | Year: 2017

MnO2 porous nanowires were prepared with an Au-coated polycarbonate membrane as the template via a simple electrodeposition method. The obtained film could be used directly as a flexible all-solid-state supercapacitor electrode. The structures of the final product were characterized by various characterization techniques including scanning electron microscopy (SEM), X-ray diffraction (XRD), FT-IR spectra, and X-ray photoelectron spectroscopic (XPS). The electrochemical results showed that MnO2 porous nanowire-based electrode materials had high capacitive performances. The areal capacitance of the prepared supercapacitor with a MnO2 deposition time of 200 s was 44.6 mF cm-2. Under different bending conditions, the areal capacitance of the supercapacitor still remained at 90.5%, indicating the highly flexible property. Furthermore, it nearly remained at 89.6% of its initial capacitive value after 2000 cycles at a current density of 0.4 mA cm-1, showing its excellent cycle stability. However, the prepared supercapacitor can power a light-emitting-diode (LED) to meet practical applications for micro-power supplies. © 2017 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.


Liu S.,Research Program in Mitochondrial Therapeutics | Soong Y.,Research Program in Mitochondrial Therapeutics | Cohen-Gould L.,New York Medical College | Manichev V.,Institute of Advanced Materials | And 2 more authors.
Journal of the American Society of Nephrology : JASN | Year: 2017

The innate immune system has been implicated in both AKI and CKD. Damaged mitochondria release danger molecules, such as reactive oxygen species, DNA, and cardiolipin, which can cause NLRP3 inflammasome activation and upregulation of IL-18 and IL-1β It is not known if mitochondrial damage persists long after ischemia to sustain chronic inflammasome activation. We conducted a 9-month study in Sprague-Dawley rats after 45 minutes of bilateral renal ischemia. We detected glomerular and peritubular capillary rarefaction, macrophage infiltration, and fibrosis at 1 month. Transmission electron microscopy revealed mitochondrial degeneration, mitophagy, and deformed foot processes in podocytes. These changes progressed over the study period, with a persistent increase in renal cortical expression of IL-18, IL-1β, and TGF-β, despite a gradual decline in TNF-α expression and macrophage infiltration. Treatment with a mitoprotective agent (SS-31; elamipretide) for 6 weeks, starting 1 month after ischemia, preserved mitochondrial integrity, ameliorated expression levels of all inflammatory markers, restored glomerular capillaries and podocyte structure, and arrested glomerulosclerosis and interstitial fibrosis. Further, helium ion microscopy vividly demonstrated the restoration of podocyte structure by SS-31. The protection by SS-31 was sustained for ≥6 months after treatment ended, with normalization of IL-18 and IL-1β expression. These results support a role for mitochondrial damage in inflammasome activation and CKD and suggest mitochondrial protection as a novel therapeutic approach that can arrest the progression of CKD. Notably, SS-31 is effective when given long after AKI and provides persistent protection after termination of drug treatment. Copyright © 2017 by the American Society of Nephrology.


Feng X.,Institute of Advanced Materials | Zhang Y.,Institute of Advanced Materials | Zhou J.,Institute of Advanced Materials | Li Y.,Institute of Advanced Materials | And 5 more authors.
Nanoscale | Year: 2015

Three-dimensional nitrogen-doped graphene (3D N-doped graphene) was prepared through chemical vapor deposition (CVD) by using porous nickel foam as a substrate. As a model, a dopamine biosensor was constructed based on the 3D N-doped graphene porous foam. Electrochemical experiments exhibited that this biosensor had a remarkable detection ability with a wide linear detection range from 3 × 10-6 M to 1 × 10-4 M and a low detection limit of 1 nM. Moreover, the fabricated biosensor also showed an excellent anti-interference ability, reproducibility, and stability. © The Royal Society of Chemistry 2015.


PubMed | Institute of Advanced Materials and New York Medical College
Type: | Journal: Journal of the American Society of Nephrology : JASN | Year: 2016

The innate immune system has been implicated in both AKI and CKD. Damaged mitochondria release danger molecules, such as reactive oxygen species, DNA, and cardiolipin, which can cause NLRP3 inflammasome activation and upregulation of IL-18 and IL-1 It is not known if mitochondrial damage persists long after ischemia to sustain chronic inflammasome activation. We conducted a 9-month study in Sprague-Dawley rats after 45 minutes of bilateral renal ischemia. We detected glomerular and peritubular capillary rarefaction, macrophage infiltration, and fibrosis at 1 month. Transmission electron microscopy revealed mitochondrial degeneration, mitophagy, and deformed foot processes in podocytes. These changes progressed over the study period, with a persistent increase in renal cortical expression of IL-18, IL-1, and TGF-, despite a gradual decline in TNF- expression and macrophage infiltration. Treatment with a mitoprotective agent (SS-31; elamipretide) for 6 weeks, starting 1 month after ischemia, preserved mitochondrial integrity, ameliorated expression levels of all inflammatory markers, restored glomerular capillaries and podocyte structure, and arrested glomerulosclerosis and interstitial fibrosis. Further, helium ion microscopy vividly demonstrated the restoration of podocyte structure by SS-31. The protection by SS-31 was sustained for 6 months after treatment ended, with normalization of IL-18 and IL-1 expression. These results support a role for mitochondrial damage in inflammasome activation and CKD and suggest mitochondrial protection as a novel therapeutic approach that can arrest the progression of CKD. Notably, SS-31 is effective when given long after AKI and provides persistent protection after termination of drug treatment.


Varelas G.,Institute of Advanced Materials | Salifoglou A.,Aristotle University of Thessaloniki | Psycharis V.,Institute of Advanced Materials
Acta Crystallographica Section C: Crystal Structure Communications | Year: 2013

The structure of the title centrosymmetric compound, [Zn(C9H6NO)2(H2O)2], has already been solved three times [Merritt, Cady & Mundy (1954). Acta Cryst. 7, 473-476; Palenik (1964). Acta Cryst. 17, 696-700; Chen, Zhang, Shi, Huang, Liang & Zhou (2003). Acta Cryst. E59, m814-m815]. The authors of the two most recent papers state that they attained lower R1 values than that obtained in the 1954 paper, but they do not mention that Merritt et al. had derived the structural model from a twinned crystal. Also, from a structural point of view, there are strong indications that the most recent report is in fact the isostructural CuII complex already reported by Okabe & Saishu [Acta Cryst. (2001), E57, m251-m252] and not the ZnII complex. The structure of the title compound is reported here based on data obtained from a twinned crystal. © 2013 International Union of Crystallography.


Elyassi B.,University of Minnesota | Wahedi Y.A.,University of Minnesota | Wahedi Y.A.,The Petroleum Institute | Rajabbeigi N.,University of Minnesota | And 9 more authors.
Microporous and Mesoporous Materials | Year: 2014

Spatially well-distributed copper-zinc oxides supported on mesoporous silica (SBA-15 and commercial silica gel) showed high adsorption capacity for hydrogen sulfide (as high as 80 mgS/gsorbent) and stability during cyclic adsorption-regeneration process.© 2014 Elsevier Inc. All rights reserved.


Deng J.,Hong Kong Baptist University | Huang Z.,Hong Kong Baptist University | Huang Z.,Institute of Advanced Materials | Huang Z.,South China University of Technology
RSC Advances | Year: 2016

There is a lack of analytical approaches to study chiroptical activity of chiral nanoplasmons. Herein, LC circuit theory is proposed to analyze the chiroptical activity of heterojunction nanospirals, revealing the main contribution to be from radiative loss. Furthermore, chiral nanoplasmonic flexible thin films exhibit excellent mechanical stability of their chiroptical activity, paving the way to develop flexible/wearable optoelectronic devices integrated with chiral nanoplasmonics. © 2016 The Royal Society of Chemistry.


Liu J.,Hong Kong Baptist University | Huang Z.,Hong Kong Baptist University | Huang Z.,Institute of Advanced Materials | Huang Z.,Partner State Key Laboratory of Environmental and Biological Analysis | Huang Z.,South China University of Technology
Nanotechnology | Year: 2015

Engineering the porosity of silicon nanowires (SiNWs) is of fundamental importance, and this work introduces a new method for doing so. Metal-assisted chemical etching (MACE) of heavily doped Si(100) creates mesoporous silicon nanowires (mp-SiNWs). mp-SiNWs are transferred from the MACE-treated wafer to a sticky tape, leaving residues composed of broken mp-SiNWs and a mesoporous Si layer on the wafer. Then the taped wafer is re-treated by MACE, without changing the etching conditions. The second MACE treatment generates mp-SiNWs that are less porous and longer than those generated by the first MACE treatment, which can be attributed to the difference in the surface topography at the beginning of the etching process. Less porous mp-SiNWs reduce optical scattering from the porous Si skeletons, and vertically protrude on the wafer without aggregation to facilitate optical trapping. Consequently, less porous mp-SiNWs effectively reduce ultraviolet-visible reflection loss. © 2015 IOP Publishing Ltd.


Zhang Y.,Institute of Advanced Materials | Shen J.,Institute of Advanced Materials | Li H.,Institute of Advanced Materials | Wang L.,Institute of Advanced Materials | And 4 more authors.
Chemical Record | Year: 2016

The detailed records and conclusions on the important advancements in graphene-based electrochemical biosensors have been reviewed. Due to their outstanding properties, graphene-based materials have been widely studied for the accurate electrochemical detection of many biomolecules, which is extremely vital to the development of biomedical instruments, clinical diagnosis, and disease treatment. This review discusses the graphene research for the effective immobilization of enzymes, including glucose oxidase, horseradish peroxidase, and hemoglobin, etc., and the accurate detection of biomolecules, including glucose, hydrogen peroxide, dopamine, ascorbic acid, uric acid, nicotinamide adenine dinucleotide, DNA, RNA, and carcinoembryonic antigen, etc. In most of the cases, the graphene-based biosensors exhibited remarkable performance with high sensitivities, wide linear detection ranges, low detection limits, and long-term stabilities. © 2015 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

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