Institute National Of Nutrition Et Of Technology Alimentaire Of Tunis

Tunis, Tunisia

Institute National Of Nutrition Et Of Technology Alimentaire Of Tunis

Tunis, Tunisia
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Karmous I.,Tunis el Manar University | Karmous I.,University of Burgundy | Karmous I.,University of Carthage | Plesnik J.,University of Burgundy | And 9 more authors.
Clinical Nutrition | Year: 2017

Background & aims: We assessed orosensory detection of a long-chain fatty acid, linoleic acid (LA), and a bitter taste marker, 6-n-propylthiouracil (PROP), and correlated lipid-taster subjects with PROP detection and polymorphism in genes encoding bitter and lipid taste receptors, respectively, TAS2R38 and CD36, in normal weight and obese subjects. Design: The normal weight (n = 52, age = 35.3 ± 4.10 years, BMI = 23.22 ± 1.44 kg/m2) and obese (n = 52, age = 35.0 ± 5.43 years, BMI = 34.29 ± 5.31 kg/m2) participants were recruited to determine fat and bitter detection thresholds. The genomic DNA was used to determine single nucleotide polymorphism (SNP) of CD36 (rs1761667) and TAS2R38 (rs1726866 and rs10246939). Results: The study included the participants who could detect LA, i.e., lipid-tasters. There was a positive correlation between BMI and detection thresholds for fat and bitter taste in normal weight and obese subjects. Obese participants showed a positive correlation between LA and PROP detection thresholds. PROP detection thresholds were higher for CD36 SNP (rs1761667) and TAS2R38 SNPs (rs1726866 and rs10246939) in obese participants compared to normal weight subjects. LA detection thresholds were not high for CD36 SNP (rs1761667) or TAS2R38 SNP (rs1726866 and rs10246939) in obese participants. Conclusions: Orosensory detection thresholds for fat and bitter taste are associated with BMI, and CD36 and TAS2R38 genotypes are not always associated with taste phenotypes. © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism.


El Fekih N.,Charles Nicolle Hospital | Kamoun I.,Institute National Of Nutrition Et Of Technology Alimentaire Of Tunis | Jones M.,Charles Nicolle Hospital | Remmeh S.,Charles Nicolle Hospital | And 3 more authors.
American Journal of Dermatopathology | Year: 2013

Langerhans cell histiocytosis is part of a larger group of syndromes described as histiocytoses. The disease may involve single or multiple systems including skin and nervous system. Here we report an adult case where Langerhans cell histiocytosis presented with diabetes insipidus and cutaneous ulcers. © 2013 Lippincott Williams & Wilkins.


Jamoussi H.,Institute National Of Nutrition Et Of Technology Alimentaire Of Tunis | Chaabouni S.,Institute National Of Nutrition Et Of Technology Alimentaire Of Tunis | Gammoudi A.,Institute National Of Nutrition Et Of Technology Alimentaire Of Tunis | Mahjoub F.,Institute National Of Nutrition Et Of Technology Alimentaire Of Tunis | And 4 more authors.
OCL - Oilseeds and fats, crops and lipids | Year: 2014

It is unanimously agreed that the omega 3 fatty acids have many health benefits and specifically, protective effects against cardiovascular and neurodegenerative diseases. The objective of this work was to estimate the spontaneous intake of alphalinolenic, docosahexaenoique (DHA), eicosapentaenoique (EPA) and linoleic acids. This observational study was conducted among 42 type 2 diabetics (21 men and 21 women) aged from 30 to 75 years. To estimate spontaneous intakes of polyinsaturated fatty acids, we used the seven days recording method. Our results showed the average daily intake of ALA was 0.99 ± 0.40 g/d or 0.42 ± 0.13 % of total energy intake. None of our patients had an adequate intake of ALA. Average daily intakes of DHA and EPA, were respectively 90.0 ± 85 mg/d and 83.5 ± 80 mg/d. As for the contribution of food to intake of EPA and DHA, fish and seafood accounted for the largest share (57%) of these fatty acids. Our results justify to strengthen nutritional education of diabetic subjects to increase the consumption of foods rich in omega 3 fatty acids and to provide an adequate report LA/ALA to multiple benefits against protection of cardiovascular diseases. © 2014 H. Jamoussi et al., Published by EDP Sciences.

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