Institute Investigaciones Medico Biologicas

Boca del Río, Mexico

Institute Investigaciones Medico Biologicas

Boca del Río, Mexico
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Cano-Contreras A.D.,Institute Investigaciones Medico Biologicas | Meixueiro-Daza A.,Institute Investigaciones Medico Biologicas | Grube-Pagola P.,Hospital Espanol Of Veracruz | Remes-Troche J.M.,Institute Investigaciones Medico Biologicas
BMJ Case Reports | Year: 2016

Peutz-Jeghers Syndrome (PJS) is an autosomal dominant intestinal polyposis syndrome characterised by the presence of hamartomatous polyps and mucocutaneous pigmentation. Prolapse of the polyps through the anus is an infrequent manifestation in children with PJS, and this complication is extremely rare in adult patients. We report the case of a 30-year-old man recently diagnosed with PJS who was seen at the emergency department because of the abrupt onset of severe anal pain with a foreign body sensation in the anal canal and rectal bleeding. Physical examination revealed a giant prolapsed polyp. © 2016 BMJ Publishing Group Ltd.


PubMed | Institute Investigaciones Medico Biologicas, Hospital Espanol Of Veracruz and Research Institute Medico Biologicas
Type: | Journal: BMJ case reports | Year: 2016

Peutz-Jeghers Syndrome (PJS) is an autosomal dominant intestinal polyposis syndrome characterised by the presence of hamartomatous polyps and mucocutaneous pigmentation. Prolapse of the polyps through the anus is an infrequent manifestation in children with PJS, and this complication is extremely rare in adult patients. We report the case of a 30-year-old man recently diagnosed with PJS who was seen at the emergency department because of the abrupt onset of severe anal pain with a foreign body sensation in the anal canal and rectal bleeding.Physical examination revealed a giant prolapsed polyp.


Rios-Galvez S.,Institute Investigaciones Medico Biologicas | Meixueiro-Daza A.,Institute Investigaciones Medico Biologicas | Remes-Troche J.M.,Institute Investigaciones Medico Biologicas
BMJ Case Reports | Year: 2015

Alcohol and tobacco abuse are the main risk factors for esophageal squamous cell carcinoma (ESCC), but other conditions that induce chronic irritation of the esophageal mucosa have also been attributed to it. For example, long-standing achalasia increases 16 times the risk of developing ESCC. We report the case of a patient with long-standing achalasia who developed ESCC. Although this complication is infrequent, it should be remembered by clinicians who treat patients with achalasia to detect early stages cancer. Copyright 2015 BMJ Publishing Group. All rights reserved.


PubMed | Institute Investigaciones Medico Biologicas
Type: | Journal: BMJ case reports | Year: 2011

Uncommon conditions such as pernicious anaemia and hypertrophic gastropathies have been considered as risk factors for gastric cancer; however, the exact increase in risk is unknown. Menetriers disease is a rare hyperproliferative disorder of the stomach caused by an overexpression of tumour growth factor , a ligand for the tyrokinase epidermal growth factor receptor, resulting in a selective expansion of surface mucous cells in the body and fundus of the stomach. There have been nearly 200 cases of Menetriers disease reported in the literature yet less than 15 have been associated with gastric adenocarcinoma. Here, we report an early stage gastric adenocarcinoma detected incidentally in a patient recently diagnosed with Menetriers disease.


PubMed | Institute Investigaciones Medico Biologicas
Type: | Journal: BMJ case reports | Year: 2015

Alcohol and tobacco abuse are the main risk factors for esophageal squamous cell carcinoma (ESCC), but other conditions that induce chronic irritation of the esophageal mucosa have also been attributed to it. For example, long-standing achalasia increases 16 times the risk of developing ESCC. We report the case of a patient with long-standing achalasia who developed ESCC. Although this complication is infrequent, it should be remembered by clinicians who treat patients with achalasia to detect early stages cancer.


PubMed | Institute Investigaciones Medico Biologicas
Type: Journal Article | Journal: Current gastroenterology reports | Year: 2010

Visceral hypersensitivity plays a key role in the pathogenesis of esophageal functional disorders such as functional heartburn and chest pain of presumed esophageal origin (noncardiac chest pain). About 80% of patients with unexplained noncardiac chest pain exhibit lower esophageal sensory thresholds when compared to controls during esophageal sensory testing (ie, esophageal barostat, impedance planimetry). Such information has led to prescription of peripherally and/or centrally acting therapies for the management of these patients. This review summarizes and highlights recent and significant findings regarding the pathophysiology, evaluation, and treatment of the hypersensitive esophagus, a central factor in functional esophageal disorders.

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