Institute Gastroenterologia

Havana, Cuba

Institute Gastroenterologia

Havana, Cuba
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Hano Garcia O.M.,Institute Gastroenterologia | Estupinan Sosa M.F.,Institute Gastroenterologia | la Rosa Hernandez D.,Institute Gastroenterologia | Gonzalez Fabian L.,Institute Gastroenterologia
Revista Cubana de Investigaciones Biomedicas | Year: 2016

Introduction: Ulcerative colitis is an inflammatory bowel disease. Little is known about its causes, but genetic, environmental, immunological and bacterial factors have been suggested. Objective: Describe the humoral immune response of patients with ulcerative colitis cared for at the Institute of Gastroenterology from January 2014 to April 2015. Methods: A descriptive cross-sectional prospective study was conducted at the Institute of Gastroenterology from January 2014 to April 2015 which included all the patients diagnosed with ulcerative colitis. An evaluation was performed of clinical, endoscopic and histological variables as well as the results of immunological studies. Results: A predominance was found of the female gender, the over-49 age group and white skin. There was also a predominance of alterations in complement components C3 and C4 and immunoglobulin G. Dependence and isolated correlation was observed between the results of immunological variables and the post-diagnosis time of evolution, the Truelove and Witts clinical scale, the degree of colonoscopic and histological activity, and the degree of dysplasia for p< 0.05. Conclusions: Immune response is a predictive factor for good evolution of the disease, but it does not allow to draw an inference about colonoscopic and histological activity. Immune response, on the other hand, is not related to the clinical evaluation scale of Truelove and Witts, the degree of dysplasia, clinical extraintestinal manifestations or post-diagnosis time of evolution. © 2016 Editorial Ciencias Medicas. All rights reserved.


Sanchez Garcia N.L.,Institute Gastroenterologia | Gonzalez Fabian L.,Institute Gastroenterologia | Garcia Bacallao E.,Institute Gastroenterologia | Lazo Del Vallin S.,Institute Gastroenterologia | Elvirez Gutierrez A.,Institute Gastroenterologia
Revista Cubana de Investigaciones Biomedicas | Year: 2016

Lymphomatous polyposis is a rare form of primary gastrointestinal that occurs mainly in older adults. This is the case of a male patient aged 74 years who had diarrheas for 2 months associated to abdominal pain, asthenia, anorexia and weight loss. Supplementary studies were performed to finally diagnose intestinal lymphomatous polyposis (Mantle cell lymphoma). © 2016, Editorial Ciencias Medicas. All rights reserved.


Perez M.R.,Hospital Nacional Of Internos | Lopez M.E.G.,Institute Gastroenterologia | Villafranca R.C.,Centro Provincial Of Higiene | Triana D.E.,Hospital Nacional Of Internos
Revista Cubana de Medicina Militar | Year: 2016

Introduction: Intestinal parasite infections are common in geographic areas where poor hygiene and sanitary conditions favor survival, reproduction and transmission of intestinal parasitism. Objectives: Evaluate the results of an educational intervention on intestinal parasitism in physicians who provide services in Primary Health Care (PHC). Methods: A descriptive, cross-sectional study was carried out with PHC physicians who previously had a survey. It was evidenced the existence of insufficient knowledge regarding intestinal parasitism. For this purpose the course "Intestinal parasitism update" was given at Dr. Miguel Enríquez Faculty of Medical Sciences, dictum 3/2013. After completing the course, a new survey was applied to evaluate the knowledge acquired. A database was made using the Microsoft Excel 2013 program. the means of the scores obtained were compared in the two evaluations using a t Student distribution through the program Epidat version 3.1. Results: 100 % of the doctors passed the second questionnaire with more than 70 points. Statistically significant differences were observed when comparing the mean scores obtained in the two evaluations (p< 0.05). Conclusions: This educational intervention was proven to be effective, as there was a statistically significant improvement of the evaluations. © 2016, Editorial Ciencias Medicas. All rights reserved.


Pascual M.G.-C.,Hospital Clinico Quirurgico Docente Joaquin Albarran | Berbes M.Z.,Hospital Clinico Quirurgico Docente Joaquin Albarran | Banos M.S.,Institute Gastroenterologia | Vazquez M.R.A.,Institute Gastroenterologia | Leyva L.M.,Hospital Dr Carlos J Finlay
Acta Gastroenterologica Latinoamericana | Year: 2011

Introduction. Medications to relief pain are more common in the everyday use during the colonoscopy practice, although schemes of medications vary. Objective. To evaluate the efficacy and the safety of propofol versus midazolam and petidhine in colonoscopy. Method. A randomized and simple-blind controlled clinical trial was carried out. We included 512 patients who underwent a colonoscopy during the period from February 2008 to January 2009. using propofol in one group and midazolam plus petidhine in another. Results. Cecal intubation was achieved in 247 patients (96.5%) with propofol and in 256 patients (100%) with midazolam plus petidhine. There were no significant differences between both methods regarding to the explored colon distance. Fifty-five patients (21.5%) had complications in the group receiving midazolam plus petidhine and 3 (1.2%) in the group receiving propofol. Complications were mild in both groups. Propofol reduced the relative risk of complications in 94.6% and absolute risk in 20.3%. Patients referred the same satisfaction degree with both methods. Conclusions. The use of propofol and midazolam plus petidhine is equally efficacious in the performance of the colonoscopy, while propofol is safer than midazolam plus propofol as a method of deep sedation.


La Rosa Hernandez D.,Institute Gastroenterologia | Gomez Cabezas E.J.,Direccion Provincial de Salud
Revista Cubana de Pediatria | Year: 2013

Two of the most important factors in the prevention of diseases in the under one-year old infants are breastfeeding and vaccination. The development of immune responses induced by vaccines requires an effective immune system in which the breastfeeding plays an essential role as an immune maturity inducer in the postnatal phase. Exclusive breastfeeding potentiates the immune responses from most of the vaccinal immunogens included in the infant vaccination programs. With the objective of expanding our knowledge on the effect of breastfeeding on vaccination, a literature review was made by using databases such as Google, Medline and the health information searcher from Infomed and breastfeeding and vaccine as subject headings.


Hierro Gonzalez A.,Institute Gastroenterologia | de Uime Ferreira E.P.,Institute Gastroenterologia | Gonzalez Fabian L.,Institute Gastroenterologia
Revista Cubana de Investigaciones Biomedicas | Year: 2016

Introduction: Gastric cancer is a serious health problem due to the complexity of its control. Objective: Describe the main clinical, epidemiological, endoscopic and histological characteristics of epithelial gastric cancer. Methods: An observational case-control study was conducted at the Institute of Gastroenterology from September 2012 to August 2014. The study sample consisted of 27 cases and 54 controls. Results: There was a predominance of the female gender (59.3 %, n= 27) and the 70-79 age group, with a mean age of 63.9 years. Epigastralgia was the most common symptom in both groups [85.2 % (cases) vs. 81.5 % (controls)]. Its association with nausea, vomiting, asthenia, anorexia and weight loss was more frequent in cases, with statistically significant differences (P= 0.008, CI= 1.39-25.31). The most common physical sign was skin and mucous pallor. The most frequent lesions were those larger than 2 cm, located in the two distal thirds of the stomach, and type III of the Paris classification. Signet ring cell carcinoma predominated (48.1 %). Conclusions: Epigastralgia associated to asthenia, weight loss and anorexia are the most common clinical symptoms in patients with epithelial gastric cancer. The most frequent histological type is signet ring cell carcinoma. © 2016, Editorial Ciencias Medicas. All rights reserved.


INTRODUCTION. The double balloon enteroscope (DBE) is a new method allows the whole visualization of the small intestine lumen. The objective of present research was to assess the experience in the carrying out of this technique in children seen in the Pediatric Endoscopy Service of the Cuban Institute of Gastroenterology. METHODS. A retrospective and descriptive study was conducted to assess the accuracy, effectiveness and extent of the double balloon enteroscope screening in the diagnosis of small intestine diseases in children. Eight patients were studied by means of physical examination and negative complementary ones of small intestine disease, seen between November, 2008 and October, 2009. In three patients there was the clinical and radiological suspicion of Crohn's disease; in other three the suspicion of small intestine tumor and remainder were seen due to hidden bleeding of intestinal origin. RESULTS. Seven procedures were applied by retrograde route and two by the anterograde one, other patient undergoes total enteroscopy using both routes. The main extent of the oral DBE was of 62,5 min with an interval of 60 to 65min and by anal route it was of 50,7 min with an interval of 45 to 60 min. In all cases it was possible to identify some lesion explaining the symptoms. CONCLUSION. Double balloon enteroscope is a safe method for the diagnosis of small intestine disease in children.


Blanco L.A.P.,Institute Gastroenterologia | Gomez E.V.,Institute Gastroenterologia | Perez Y.M.,Institute Gastroenterologia | Bertot L.C.,Institute Gastroenterologia
Acta Gastroenterologica Latinoamericana | Year: 2013

A review about nonalcoholic fatty liver disease is presented, considering the updated aspects related to pathophysiology, diagnosis and management of this medical condition.


La Rosa Hernandez D.,Institute Gastroenterologia | Gomez Cabeza E.J.,Institute Gastroenterologia | Sanchez Castaneda N.,Institute Gastroenterologia
Revista Cubana de Pediatria | Year: 2014

Intestinal microbiota covers the set of commensal microorganisms that live together with the individual. The intrauterine programming and further colonization are determining factors in maturation of the immune system. With the purpose of expanding our knowledge on the effect of the intestinal microbiota in the child´s immune system maturation, a literature review was made supported on Google, Medline databases and the Infomed health information searcher and using intestinal microbiota, immune system, gut microbiota as subject headings. © 2014 Editorial Ciencias Medicas. All rights reserved.


PubMed | Institute Gastroenterologia
Type: Journal Article | Journal: Acta gastroenterologica Latinoamericana | Year: 2013

A review about nonalcoholic fatty liver disease is presented, considering the updated aspects related to pathophysiology, diagnosis and management of this medical condition.

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