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Pascual M.G.-C.,Hospital Clinico Quirurgico Docente Joaquin Albarran | Berbes M.Z.,Hospital Clinico Quirurgico Docente Joaquin Albarran | Banos M.S.,Institute Gastroenterologia | Vazquez M.R.A.,Institute Gastroenterologia | Leyva L.M.,Hospital Dr Carlos J Finlay
Acta Gastroenterologica Latinoamericana | Year: 2011

Introduction. Medications to relief pain are more common in the everyday use during the colonoscopy practice, although schemes of medications vary. Objective. To evaluate the efficacy and the safety of propofol versus midazolam and petidhine in colonoscopy. Method. A randomized and simple-blind controlled clinical trial was carried out. We included 512 patients who underwent a colonoscopy during the period from February 2008 to January 2009. using propofol in one group and midazolam plus petidhine in another. Results. Cecal intubation was achieved in 247 patients (96.5%) with propofol and in 256 patients (100%) with midazolam plus petidhine. There were no significant differences between both methods regarding to the explored colon distance. Fifty-five patients (21.5%) had complications in the group receiving midazolam plus petidhine and 3 (1.2%) in the group receiving propofol. Complications were mild in both groups. Propofol reduced the relative risk of complications in 94.6% and absolute risk in 20.3%. Patients referred the same satisfaction degree with both methods. Conclusions. The use of propofol and midazolam plus petidhine is equally efficacious in the performance of the colonoscopy, while propofol is safer than midazolam plus propofol as a method of deep sedation.


La Rosa Hernandez D.,Institute Gastroenterologia | Gomez Cabezas E.J.,Direccion Provincial de Salud
Revista Cubana de Pediatria | Year: 2013

Two of the most important factors in the prevention of diseases in the under one-year old infants are breastfeeding and vaccination. The development of immune responses induced by vaccines requires an effective immune system in which the breastfeeding plays an essential role as an immune maturity inducer in the postnatal phase. Exclusive breastfeeding potentiates the immune responses from most of the vaccinal immunogens included in the infant vaccination programs. With the objective of expanding our knowledge on the effect of breastfeeding on vaccination, a literature review was made by using databases such as Google, Medline and the health information searcher from Infomed and breastfeeding and vaccine as subject headings.


Hierro Gonzalez A.,Institute Gastroenterologia | de Uime Ferreira E.P.,Institute Gastroenterologia | Gonzalez Fabian L.,Institute Gastroenterologia
Revista Cubana de Investigaciones Biomedicas | Year: 2016

Introduction: Gastric cancer is a serious health problem due to the complexity of its control. Objective: Describe the main clinical, epidemiological, endoscopic and histological characteristics of epithelial gastric cancer. Methods: An observational case-control study was conducted at the Institute of Gastroenterology from September 2012 to August 2014. The study sample consisted of 27 cases and 54 controls. Results: There was a predominance of the female gender (59.3 %, n= 27) and the 70-79 age group, with a mean age of 63.9 years. Epigastralgia was the most common symptom in both groups [85.2 % (cases) vs. 81.5 % (controls)]. Its association with nausea, vomiting, asthenia, anorexia and weight loss was more frequent in cases, with statistically significant differences (P= 0.008, CI= 1.39-25.31). The most common physical sign was skin and mucous pallor. The most frequent lesions were those larger than 2 cm, located in the two distal thirds of the stomach, and type III of the Paris classification. Signet ring cell carcinoma predominated (48.1 %). Conclusions: Epigastralgia associated to asthenia, weight loss and anorexia are the most common clinical symptoms in patients with epithelial gastric cancer. The most frequent histological type is signet ring cell carcinoma. © 2016, Editorial Ciencias Medicas. All rights reserved.


INTRODUCTION. The double balloon enteroscope (DBE) is a new method allows the whole visualization of the small intestine lumen. The objective of present research was to assess the experience in the carrying out of this technique in children seen in the Pediatric Endoscopy Service of the Cuban Institute of Gastroenterology. METHODS. A retrospective and descriptive study was conducted to assess the accuracy, effectiveness and extent of the double balloon enteroscope screening in the diagnosis of small intestine diseases in children. Eight patients were studied by means of physical examination and negative complementary ones of small intestine disease, seen between November, 2008 and October, 2009. In three patients there was the clinical and radiological suspicion of Crohn's disease; in other three the suspicion of small intestine tumor and remainder were seen due to hidden bleeding of intestinal origin. RESULTS. Seven procedures were applied by retrograde route and two by the anterograde one, other patient undergoes total enteroscopy using both routes. The main extent of the oral DBE was of 62,5 min with an interval of 60 to 65min and by anal route it was of 50,7 min with an interval of 45 to 60 min. In all cases it was possible to identify some lesion explaining the symptoms. CONCLUSION. Double balloon enteroscope is a safe method for the diagnosis of small intestine disease in children.


Hierro Gonzalez A.,Institute Gastroenterologia | Hano Garcia O.M.,Institute Gastroenterologia | Gonzalez Fabian L.,Institute Gastroenterologia
Revista Cubana de Medicina Tropical | Year: 2013

Introduction: filariae are nematodes from the family Filariidae. There are about 200 parasitic filariae, but only a few infect humans. Objectives: make a brief description of these parasitic diseases which may serve as guidance to the large number of Cuban cooperation doctors in African countries, where this condition is particularly common, and describe the behavior of filarial infections in patients cared for at Mouila Regional Hospital in Gabon. Methods: a cross-sectional observational descriptive study was conducted of 87 patients of both sexes aged 15 and over with confirmed filariasis. Results: it was found that 3.7% of patients had some kind of filariasis: 93.1% due to Loa loa, 5.7% due to Mansonella perstans and 1.1% due to coinfection by both. Females and persons over 65 were the most affected groups. The most common symptom was pruritus (59.8%), followed by polyarthralgia, lumbar pain and asthenia. Eosinophilia was present in 100% of subjects, and anemia was more frequent in patients infected with Mansonella perstans. Infection intensity was low in both filariases. The response was satisfactory in 86.1% of the patients treated with diethylcarbamazine and 82.4% of those treated with ivermectin. Conclusions: Loa loa was predominant mainly among women. Pruritus, anemia and eosinophilia were the main manifestations. Treatment with ivermectin was found to be effective.


Jimenez O.M.V.,Institute Gastroenterologia | Carbonell A.E.,Hospital Pediatrico Universitario Pedro Borras | Garcia O.M.H.,Institute Gastroenterologia | Rodriguez L.W.,Institute Gastroenterologia | And 2 more authors.
Acta Gastroenterologica Latinoamericana | Year: 2012

Introduction. Celiac disease (EC) not diagnosed or treated affect histological, immunological and nutritional status of patients who suffer it. These changes allow infection by parasites that cause no symptoms in immunocompetent patients, such as Blastocystis hominis (Bh). Objetive. To analyze the presence of Bh in symptomatic celiac patients and describe the clinical, histological, immune and nutritional status in these patients. Material and method. An observational descriptive cross sectional study was performed. Thirty symptomatic celiac patients (18 women, mean age 41 years old, range 19-68 years), assisted at the Institute of Gastroenterology of Cuba from January to December 2009, entered the study. Results. Diarrhea and chronic anemia were the most commonly reported clinical manifestations (22 and 4 patients, respectively). The analysis of more than five Bh per field was more frequent in the group of patients studied (63.3%), with statistically significant difference in patients with villous atrophy and low weight (P < 0.03) compared to cases with less than five Bh per field. No significant differences were found when the immune status of patients was analyzed. Conclusions. In symptomatic celiac patients with subtotal-total villous atrophy and low weight the finding of more than five Bh per field should be considered as opportunistic.


Blanco L.A.P.,Institute Gastroenterologia | Gomez E.V.,Institute Gastroenterologia | Perez Y.M.,Institute Gastroenterologia | Bertot L.C.,Institute Gastroenterologia
Acta Gastroenterologica Latinoamericana | Year: 2013

A review about nonalcoholic fatty liver disease is presented, considering the updated aspects related to pathophysiology, diagnosis and management of this medical condition.


Gonzalez A.H.,Institute Gastroenterologia | Garcia O.M.H.,Institute Gastroenterologia | Fabian L.G.,Institute Gastroenterologia
Revista Cubana de Medicina Tropical | Year: 2013

Introduction: herpes zoster results from the viral reactivation of the zoster's varicella in the ganglion of the sensitive nerves, and is regularly associated to depression of the immunological system as is in the case of AIDS. Objective: to determine positivity for HIV in patients with Herpes Zoster. Methods: an observational, descriptive and cross-sectional study, which included all the 15 years-old or over patients of both sexes who went to the emergency service of the regional hospital in Mouila, Gabon and who presented characteristic herpes zoster lesions, was conducted. Results: in the studied patients, 74.13 % with herpes zoster were HIV-positive, males prevailed and the average age was 29.9 years old. In the majority of the cases, pain was the initial symptom and the more frequent location was the thorax. The location of several dermatomes was found in 16.27 % of the patients. Pre herpetic neuralgia averaged 3,209 days depending on the type of affected dermatome, being the cranial one the shortest. The most frequent complication was the post-zoster neuritis. Type I HIV was predominant; the LTCD4+ values ranged 200 to 499 cell/mm3. The treatment response was inadequate in patients with two types of HIV and the LTCD4+ count was below 500 cell/mm3. Conclusions: the presence of herpes zoster in young persons living in high AIDS/HIV incidence areas could be both a good clinic indicator of seropositivity and one of the disease manifestations.


La Rosa Hernandez D.,Institute Gastroenterologia | Gomez Cabeza E.J.,Institute Gastroenterologia | Sanchez Castaneda N.,Institute Gastroenterologia
Revista Cubana de Pediatria | Year: 2014

Intestinal microbiota covers the set of commensal microorganisms that live together with the individual. The intrauterine programming and further colonization are determining factors in maturation of the immune system. With the purpose of expanding our knowledge on the effect of the intestinal microbiota in the child´s immune system maturation, a literature review was made supported on Google, Medline databases and the Infomed health information searcher and using intestinal microbiota, immune system, gut microbiota as subject headings. © 2014 Editorial Ciencias Medicas. All rights reserved.


PubMed | Institute Gastroenterologia
Type: Journal Article | Journal: Acta gastroenterologica Latinoamericana | Year: 2013

A review about nonalcoholic fatty liver disease is presented, considering the updated aspects related to pathophysiology, diagnosis and management of this medical condition.

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