Hermine O.,Institute for Research in BioMedecine and Epidemiology of Sport |
Hermine O.,French National Center for Scientific Research |
Hermine O.,Institute of Genetic Diseases |
Hermine O.,University of Paris Descartes |
And 30 more authors.
Biochimie | Year: 2015
The HFE gene encodes a protein involved in iron homeostasis; individuals with mutations in both alleles develop hemochromatosis. 27% of the French population is heterozygous for mutations in this gene. We found that 80% of the French athletes who won international competitions in rowing, Nordic skiing and judo display mutations in one allele of HFE, thus demonstrating the existence of a favourable phenotype linked to this heterozygosity. © 2015 Published by Elsevier B.V.