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Gacesa J.P.,University of Novi Sad | Dragnic N.R.,Institute for Public Health of Vojvodina | Prvulovic N.M.,Institute for Oncology Sremska Kamenica | Barak O.F.,University of Novi Sad | Nikola G.,University of Novi Sad
Journal of Sports Sciences | Year: 2011

The aim of this study was to determine whether triceps brachii muscle volume can be adequately estimated from a single anatomical cross-sectional area (ACSA) and can the same model be used for prediction after training. Thirty-five healthy male non-athletes (age 21.6 ± 2.5 years, body mass index 24.8 ± 3.5 kg m-2) volunteered for this study. The volumes of the upper arm extensors were calculated from magnetic resonance imaging (MRI) sequence scans and regression models were developed, which were used to predict muscle volumes from single MRI cross-sectional scans taken at different points along the humerus length. The same procedure was repeated after 12 weeks of maximal resistance training of the elbow extensors. Correlation coefficients were calculated for Model A with CSAmax, humerus length (HL), and body mass index (r = 0.919), a model with CSA50% and HL (r = 0.922), and a model with CSA60% and HL (r = 0.920) (P 50.001). The standard error of estimate for Model A, Model CSA50%, and Model CSA60% was 8.0%, 7.7%, and 7.8% respectively. The same prediction formula can be used for the left arm (r = 0.904). If a single ACSA is used for triceps brachii volume prediction, the best fit is with Model CSA60% and HL, both before and after training (r = 0.941). By introducing humerus length into the calculation, we simplify the procedure for volume measurement, since it can be obtained during MRI scanning. © 2011 Taylor & Francis. Source

Gacesa J.Z.P.,University of Novi Sad | Jakovljevic D.G.,Newcastle University | Kozic D.B.,Center for Imaging Diagnostics | Dragnic N.R.,Institute for Public Health of Vojvodina | And 2 more authors.
Clinical Physiology and Functional Imaging | Year: 2010

Summary: The aim of this study was to determine morphological and functional changes of the elbow extensor muscles in response to a 12-week self-perceived maximal resistance training (MRT). Twenty-one healthy sedentary young men were engaged in elbow extensor training using isoacceleration dynamometry for 12 weeks with a frequency of five sessions per week (five sets of ten maximal voluntarily contractions, 1-min rest period between each set). Prior to, at 6 weeks and after the training, a series of cross-sectional magnetic resonance images of the upper arm were obtained and muscle volumes were calculated. Maximal and endurance strength increased (P<0.01) by 15% and 45% at 6 weeks, and by 29% and 70% after 12 weeks compared with baseline values, while fatigue rate of the elbow extensors decreased by 67%. The volume of triceps brachii increased in both arms (P<0.01) by 4% at 6 weeks, and by 8% after 12 weeks compared with baseline values (right arm - from 487.4 ± 72.8 cm3 to 505.8 ± 72.3 cm3 after 6 weeks and 525.3 ± 73.7 cm3 after 12 weeks; left arm - from 475.3 ± 79.1 cm3 to 493.2 ± 72.7 cm3 after 6 weeks and 511.3 ± 77.0 cm3 after 12 weeks). A high correlation was found between maximal muscle strength and muscle volume prior (r2 = 0.62) and after (r2 = 0.69) the training (P<0.05). A self-perceived MRT resulted in an increase in maximal and endurance strength. Morphological adaptation changes of triceps brachii as a result of 12-week specific strength training can explain only up to 26% of strength gain. © 2010 The Authors. Clinical Physiology and Functional Imaging © 2010 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Source

Sevic S.,University of Novi Sad | Stefan-Mikic S.,University of Novi Sad | Sipovac D.,Health Care Center Novi Sad | Turkulov V.,University of Novi Sad | And 2 more authors.
Vojnosanitetski Pregled | Year: 2015

Background/Aim. West Nile virus (WNV) is a neurotropic RNA virus particle which belongs to the Flaviviridae family, genus Flavivirus. It is sustained in arthropods within the transmission cycle between the mosquitoes and birds. Most commonly (80% of cases) WNV infections are asymptomatic among people. Less than 1% of patients develop neuroinvasive forms of the disease – meningitis, encephalitis, or acute flaccid paralysis. The aim of the research was to determine most common clinical and laboratory manifestations, to emphazise the presence of comorbidities and outcomes of treatment among patients with WNV infection. Methods. This retrospective study, which was conducted in the period from January 1, 2012 to December 31, 2013, evaluated 32 patients who were diagnosed with WNV infection based on clinical findings, laboratory, and serological tests. To assess statistical significance we used χ2, and t-test. Results. The study involved 22 (69%) males and 10 (31%) females aged from 31 to 65 years. On admission, there were 16 (50%) febrile individuals, 27 (84.4%) with positive meningeal signs, 17 (53.2%) with pathological neurological signs, and 10 (31.3%) with consciousness disorders. WNV infection was confirmed by the method enzyme linked immuno sorbent assay (ELISA) in all the patients, while Reverse Transcription Polymerase Chain Reaction (RT-PCR) test was positive in 3 (30%) of the tested patients. Cardiovascular comorbidities dominated in 7 (21.9%) of the cases. Full recovery was accomplished in 87.5 % of the cases. Conclusion. The results of our study show that the absence of meningeal signs and fever on the day 7 of hospital treatment are indicators of good course and prognosis of neuroinvasive forms of WNV infection. Comorbidities do not increase the risk of disease. ELISA test is a sovereign diagnostic method. In most cases, after the administered symptomatic therapy, the complete recovery of patients was achieved. © 2015, Institut za Vojnomedicinske Naucne Informacije/Documentaciju. All rights reserved. Source

Kovacevic G.,Institute for Public Health of Vojvodina | Nikolic N.,Institute for Public Health of Vojvodina | Jovanovic-Galovic A.,Institute for Public Health of Vojvodina | Hrnjakovic-Cvjetkovic I.,University of Novi Sad | And 3 more authors.
Turkish Journal of Medical Sciences | Year: 2016

Background/aim: The aim of this study was to determine the presence and age distribution of different oncogenic human papilloma virus (HPV) types in women in the South Backa region and its relationship to Pap results. Materials and methods: In a group of 1087 women with normal and abnormal cytology, the commercial HR HPV Real-TM kit (Sacace Biotechnologies, Italy) was used. Results: Overall, 50.5% of the women were HPV positive. The presence of HPV types 18, 31, 51, and 58 was significantly influenced by age, while the presence of HPV types 16 and 45 was significantly influenced by cervical cytology. Results of the LSD test show a wide spectrum of high risk HPV among women with normal cytology and women with a low grade cervical lesion rate (atypical squamous cell of undetermined significance (ASCUS) and low grade squamous intraepithelial lesions (LSIL). The most prevalent HPV types found were 16, 31, 51, 18, and 52. In the HSIL group the most prevalent HPV types were 16 and 45. Conclusion: The reported results provide new data on the circulation of oncogenic HPV genotypes and frequency of multiple infections among women in Vojvodina and suggest that a prophylactic vaccine against HPV 16 and 18 has the potential to prevent approximately half of the high-grade lesions. © TÜBITAK. Source

Kovacevic G.,Institute for Public Health of Vojvodina | Jovanovic-Galovic A.,Institute for Public Health of Vojvodina | Petrovic V.,Institute for Public Health of Vojvodina | Vinarz Z.,Institute for Health Protection of Students | And 3 more authors.
Srpski Arhiv za Celokupno Lekarstvo | Year: 2016

Introduction Cervical cancer, attributed to human papillomavirus (HPV) infection, represents the fourth most common and lethal cancer in Serbian women, and the second most common cancer in women aged 15–44. Objective The aim of the study was to determine the presence of high-risk and low-risk HPV types in population of unvaccinated female university students in Novi Sad, Serbia, and to evaluate possible risk factors for HPV infection. Methods Sample consisted of 250 young women (19–26 years of age) attending outpatient clinics for screening gynecological examination. All participants in the study completed a specially designed anonymous questionnaire. For the detection of HPV DNA, two commercial kits–High Risk HPV Real-TM and Low Risk HPV 6/11 Real-TM (Sacace Biotechnologies, Como, Italy) were used. Thirty positive samples were retested by GenoFlow HPV Array Test (DiagCor Bioscience Incorporation Limited, Hong Kong, China). Results The overall prevalence rate of HPV was 61.6%. The most common HPV types in the present study were as follows: HPV 16, 31, 51, 52, and 18. Female students with only one sexual partner had significantly lower chance of having HPV infection. Other variables describing lifestyle did not show statistical significance. Conclusion The present paper provides data on the prevalence of high- and low-risk HPV genotypes among university students in Novi Sad. Obtained results indicate the need for educational activities on sexually transmitted infections, including HPV, together with promotion of healthy lifestyles. According to our results, bivalent and quadrivalent prophylactic vaccines have the potential to prevent over 50% of infections. Percentage of protection with a second-generation prophylactic nonavalent vaccine would be more than 80%. © 2016. Srpski Arhiv za Celokupno Lekarstvo. All right reserved. Source

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