Quality of four herbal drugs for Traditional Chinese Medicine from experimental cultivation in Germany compared to import sources: Identity, sensory characteristics, active constituents and purity [Qualitätsvergleich vier chinesischer Heilpflanzen: Aus bayerischem Versuchsanbau im Vergleich zu Importware: Identität, sensorische Eigenschaften, Inhaltsstoffe und Reinheit]
Holzapfel C.,Institute For Pflanzenbau Und Pflanzenzuchtung |
Seidenberger R.,Institute For Pflanzenbau Und Pflanzenzuchtung |
Schmucker R.,PhytoLab GmbH and Co. KG. |
Torres-Londono P.,Krauter Mix GmbH |
Heuberger H.,Institute For Pflanzenbau Und Pflanzenzuchtung
Zeitschrift fur Arznei- und Gewurzpflanzen | Year: 2015
In the frame of the interdisciplinary project on the field production of Chinese herbal raw material in Germany, quality of drugs from experimental cultivation in Bavaria was compared to quality of imported drugs from China since 2004 by examining identity, purity, active principle content as well as sensory quality. In this paper, results are presented for species whose local cultivation was about to be realized: Glycyrrhiza glabra/G. uralensis, Paeonia lactiflora (radix rubra), Rheum officinale/R. palmatum and Xanthium sibiricum. Overall, drugs from experimental cultivation performed very well and the results have shown that local German cultivation can lead to good, secure, controlled drugs. The first lots of Paeoni ae Radix rubra originating from German commercial cultivation have confirmed this expectation.
Traditional Chinese pharmacotherapy in patients with chronic rhinosinusitis – An observational trial considering the origin of medicinal drugs [Traditionelle chinesische Arzneitherapie bei Patienten mit chronischer Rhinosinusitis-eine Therapiebeobachtung mit Berücksichtigung der Arzneimittelherkunft]
Hummelsberger J.,Societas Medicinae Sinensis |
Friedl F.,Klinik Silima |
Gaus W.,University of Ulm |
Kohnen R.,RPS Research Germany GmbH |
And 5 more authors.
Forschende Komplementarmedizin | Year: 2015
Background: The use of Chinese medicinal drugs is becoming more common in Germany. However, the import from China results in aggravated quality controls and potentially jeopardized therapeutic safety. Therefore, in 1999 the Bavarian Department for Agriculture has initiated an interdisciplinary research project to cultivate and analyze important Chinese herbal plants. Currently 16 Bavarian-produced Chinese drugs are in use and distributed to patients by pharmacies. Despite a comparable quality of Bavarian pharmaceutical products, there are concerns remaining as the Bavarian medical drugs have been used for treatment purposes on patients since 2006, without their effect having been compared to the Chinese products. Therefore we performed an observational trial using a parallel group design on patients with chronic rhinosinusitis. Methods: The duration of the trial was 4 weeks. After a 4-week follow-up, the patients were interviewed via telephone. During the trial the patients were given 2 × 50 ml of a decoction of Chinese medicinal herbs, either (a) from Bavarian controlled cultivation (Bavaria group) or (b) from Chinese production (China group). The therapeutic success was evaluated using numerical rating scales. Results: In total, 64 patients completed the observational trial (31 Bavaria group, 33 China group). Both groups showed significant improvements in the main symptom scores of chronic rhinosinusitis as well as in secondary symptoms, such as the overall state of health or the tendency to catch a cold. There were no significant differences between the groups concerning the main symptoms scores. Overall the herbal decoctions had no severe side effects. Conclusion: This observational trial shows that Chinese herbal drugs from Bavarian cultivation are as effective as medicinal herbs imported from China, but the effects of concomitant therapies must be considered as well. The symptom score improvements during the treatment period were obvious and should stimulate further investigation on the efficacy of this herbal formula in the treatment of chronic rhinosinusitis. © 2015 S. Karger GmbH, Freiburg.
Monitoring of total copper contents in organically and conventionally managed soils. Part 2: Total contents in German hop soils [Erhebung von Kupfergesamtgehalten in ökologisch und konventionell bewirtschafteten böden. teil 2: Gesamtgehalte in böden deutscher hopfenanbaugebiete]
Strumpf T.,Julius Kuhn Institute |
Engelhard B.,Institute For Pflanzenbau Und Pflanzenzuchtung |
Weihrauch F.,Institute For Pflanzenbau Und Pflanzenzuchtung |
Riepert F.,Julius Kuhn Institute |
Steindl A.,Julius Kuhn Institute
Journal fur Kulturpflanzen | Year: 2011
Soil samples were taken from 9 conventionally and 4 organically managed hop growing sites, considering all aspects that are relevant for a representative assessment of copper loads. The result of this survey is intended to enable the selection of characteristical cultivation types for each site, which, in combination with a refined exposure analysis, are a prerequisite for the assessment of the effects of copper on earthworm coenoses. Based on total contents, the copper load and its distribution on test and reference fields of German hop cultivation sites is presented. Additionally, the heavy metal content was determined in general, and differences in copper contents between and within hop rows were identified. The management history of the hop sites led to additional heavy metal soil contamination (As, Cr, Pb, Zn, V). Due to different cultural measures exercised in the past, the analyzed total heavy metal contents differ between growing regions. Comparing literature with managing history and current management, it is obvious that peaks of contamination result from applications between 1924 and 1965, when for the control of plant diseases up to 60 kg copper per ha and year were used. The collected data concerning load situation, site description and duration of management suggest that three hop sites are appropriate for a biological assessment of soil quality and its recent impact on earthworm coenoses.
Maurer K.A.,Institute For Pflanzenbau Und Pflanzenzuchtung |
Berg G.,University of Graz |
Seefelder S.,Institute For Pflanzenbau Und Pflanzenzuchtung
Gesunde Pflanzen | Year: 2014
Verticillium wilt is a devastating disease in hops and causes considerable crop losses. V. albo-atrum is the most widespread species, whereas V. dahliae is rarely found. Due to the survival of the fungus for several years in soil by resting structures and the lack of effective chemical control, a fast detection method is needed. One aim of this study was to evaluate the occurrence of Verticillium spp. in the Hallertau region (Germany). Therefore, 76 hop plants, with or without wilt symptoms, were analyzed using a real time PCR (polymerase chain reaction) assay. V. albo-atrum was identified in 57 bine samples. The pathogen can sporadically appear without showing visual symptoms. The abundance of the fungus inside the plants was analyzed. Furthermore, four beneficial bacteria, Burkholderia terricola ZR2-12, Pseudomonas poae RE*1-1-14, Serratia plymuthica 3Re4-18, and Stenotrophomonas rhizophila DSM14405T, were evaluated as biological control agents in hops. The colonization competence in the root system, plant growing promotion, and antagonistic effects were assessed. All strains colonized the endorhiza and the rhizosphere. The bacterial strains B. terricola ZR2-12, S. plymuthica 3Re4-18, and S. rhizophila DSM14405T are promising candidates for further biocontrol strategies. Thus, first steps towards the biological control of Verticillium wilt were presented. © 2014 Springer-Verlag Berlin Heidelberg.
Bomme U.,Institute For Pflanzenbau Und Pflanzenzuchtung |
Rinder R.,Institute For Pflanzenbau Und Pflanzenzuchtung
Zeitschrift fur Arznei- und Gewurzpflanzen | Year: 2010
The knowledge of the apparent density and required space of harvested medicinal and spice plant materials is important to calculate the required capacity of the harvest, transport, processing and storage facilities. However, such information is hardly available. Therefore, in 1990 through 2008, the Bavarian State Research Center for Agriculture has determined the apparent density and the required space of different plant parts of 42 plant species. Although only a few samples were available for some species, the data can offer rough reference points. A large differentiation among the species has to be considered. The apparent density of fresh plant parts varied from 49 to 491 kg/m3 and of dried plant parts from 17 to 707 kg/m3 for the studied plant species. © Agrimedia GmbH & Co KG 2010.