Institute Biophytis | Date: 2010-07-06
Bleaching preparations for household laundry use; cleaning, polishing, scouring and abrasive preparations; soaps; perfumes, essential oils, cosmetics, hair lotions; dentifrices; depilatories; make-up removing preparations; lipstick; beauty masks; Preservative for leather being polish; creams for leather. Dietetic substances and foods for medical use, namely, dietary food supplements and nutraceuticals with health claims, nutritionally fortified food products adapted for medical use, dietary fiber, dietetic foods adapted for medical use, enzyme foods supplements; food for babies; medicinal plants and herbs; herbal teas for health purposes; Phytotherapeutic medicines for the prevention and treatment of obesity, metabolic syndrome and diabetes. Processed functional foods being prepared meals made primarily with meat, fish, poultry and game, fruit and vegetables; eggs, milk, edible oils and fats, canned crustaceans; milk beverages, with milk predominating; meat extracts for the preparation of food products, poultry and game extracts for making food products; fruit and vegetable extracts for making food products; egg extracts for making food products, milk extracts for making food products, edible oils and fats for making food products, processed extracts of crustaceans for making food products; milk beverages, with milk predominating for making food products. Food supplements and functional dietary foods made primarily with coffee, tea, cocoa, sugar, rice, tapioca, sago, cereals, flour, yeast, salt, mustard, and vinegar; coffee extracts for making foodstuffs, cocoa extracts for making foodstuffs, sugar for making foodstuffs, extracts of rice for making foodstuffs, extracts of tapioca for making foodstuffs, cereal extracts for making foodstuffs, flour, yeast for making foodstuffs, extracts of salt, and mustard; vinegar for making foodstuffs. Food supplements being syrup for making beverages made with mineral and carbonated water; fruit juices and beverages in the nature of energy water, fruit flavored drinks, juice base concentrates, syrups and other preparations in the nature of extract of must, extracts of hops, tomato juice and essences for making beverages, lemonades, fruit nectars; soda water; mineral water and sparkling, fruit drinks and fruit juices, lemonades, fruit nectars; soda water.
Institute Biophytis | Date: 2010-12-21
Bleaching preparations for laundry purposes; cleaning, polishing, scouring and abrasive preparations; soaps; perfumes, essential oils, cosmetics, hair lotions; dentifrices; depilatories; make-up removing preparations; lipstick; beauty masks, shaving products, namely shaving lotions, shaving creams, shaving foam. Pharmaceutical preparations for the treatment of aging associated pathologies, chronic skin aging pathologies, obesity associated chronic diseases, diabetes, sarcopenic obesity and cardiovascular diseases, sanitary preparations for medical purposes; material for stopping teeth, dental wax; preparations for destroying vermin; fungicides; herbicides; medicated bath preparations; sanitary pads, pants or towels; chemical preparations for medical or pharmaceutical purposes, namely, nutraceutical for the treatment of aging associated pathologies, chronic skin aging pathologies, obesity associated chronic diseases, diabetes and cardiovascular diseases; parasiticides; dietetic sugar for medical purposes; alloys of precious metals for dental purposes; dietetic food for medical purposes produced by organic farming or made from goods produced by organic farming, food for babies produced by organic farming or made from goods produced by organic farming. Meat, fish, poultry and game; meat extracts; preserved, dried and cooked fruits and vegetables; jellies; jams; compotes; eggs; milk and milk products, excluding ice cream, ice milk and frozen yogurt; edible oils and fats; fats for food; butter; charcuterie; crustaceans, not live; tinned meat or fish; cheeses; milk beverages being milk predominated; all the above goods are produced by organic farming or made from goods produced by organic farming. Coffee; tea; cocoa; sugar; rice; tapioca; sago; artificial coffee; flours; bread; pastries; edible ices; honey; treacle; yeast, baking-powder; salt; mustard; vinegar; condiments, namely, sauces; spices; ice for refreshment; sandwiches; pizzas; food, namely, pancakes; cookies and biscuits; cakes; rusks; chocolate; cocoa based beverages; coffee based beverages, chocolate based beverages with milk; tea based beverages; all the above goods are produced by organic farming or made from goods produced by organic farming. Beers; mineral and sparkling waters; fruit beverages; fruit juices; syrups for making beverages; lemonades; fruit nectars; soda water; non-alcoholic aperitifs; all the above goods are produced by organic farming or made from goods produced by organic farming. Evaluation, assessment and research in the fields of science and technology provided by engineers, namely, engineering in the field of life science; design and development of computers and software; research and development of new products, for others; architectural design; interior design; development, design, installation, maintenance, updating or rental of software; computer programming; computer consultancy; data conversion of computer programs and data, other than physical conversion; conversion of documents from a physical to an electronic medium; vehicle road-worthiness testing; graphic arts designing; authentication of works of art; scientific research for medical purposes.
Foucault A.-S.,French National Institute for Agricultural Research |
Foucault A.-S.,Agro ParisTech |
Foucault A.-S.,Institute Biophytis |
Even P.,French National Institute for Agricultural Research |
And 13 more authors.
Physiology and Behavior | Year: 2014
In a previous study, we have demonstrated that a supplementation of a high-fat diet with a quinoa extract enriched in 20-hydroxyecdysone (QE) or pure 20-hydroxyecdysone (20E) could prevent the development of obesity. In line with the anti-obesity effect of QE, we used indirect calorimetry to examine the effect of dietary QE and 20E in high-fat fed mice on different components of energy metabolism. Mice were fed a high-fat (HF) diet with or without supplementation by QE or pure 20E for 3. weeks. As compared to mice maintained on a low-fat diet, HF feeding resulted in a marked physiological shift in energy homeostasis, associating a decrease in global energy expenditure (EE) and an increase in lipid utilization as assessed by the lower respiratory quotient (RQ). Supplementation with 20E increased energy expenditure while food intake and activity were not affected. Furthermore QE and 20E promoted a higher rate of glucose oxidation leading to an increased RQ value. In QE and 20E-treated HFD fed mice, there was an increase in fecal lipid excretion without any change in stool amount. Our study indicates that anti-obesity effect of QE can be explained by a global increase in energy expenditure, a shift in glucose metabolism towards oxidation to the detriment of lipogenesis and a decrease in dietary lipid absorption leading to reduced dietary lipid storage in adipose tissue. © 2014. Source
Guibout L.,Paris-Sorbonne University |
Guibout L.,Institute Biophytis |
Mamadalieva N.,Institute of the Chemistry of Plant Substances |
Balducci C.,Institute Biophytis |
And 2 more authors.
Phytochemical Analysis | Year: 2015
Introduction Ajuga turkestanica is a plant used in traditional medicine for its high ecdysteroid content, including the presence of the particularly active turkesterone, which possess efficient anabolic activity. Objectives To isolate and identify minor ecdysteroids present in a semi-purified plant fraction containing ca. 70% turkesterone. Material and Methods Multi-step preparative HPLC (combining RP- and NP-HPLC systems) was used to purify the different components present in the turkesterone fraction. Isolated compounds were identified by high-resolution mass spectrometry and 2D-NMR. Results Fourteen ecdysteroids (including turkesterone and 20-hydroxyecdysone) were isolated. Seven of these, all bearing an 11α-hydroxy group, were previously unreported. Conclusion Ajuga turkestanica ecdysteroids are characterised by the abundance of 11α-hydroxylated compounds and by the simultaneous presence of 24C, 27C, 28C and 29C ecdysteroids. It is expected that even more ecdysteroids are to be found in this plant since the starting material for this study lacked the less polar ecdysteroids. The simultaneous presence of 20-hydroxyecdysone and turkesterone (its 11α-hydroxy analogue) as the two major ecdysteroids suggests that every ecdysteroid is probably present in both 11α-hydroxy and 11-deoxy forms. Copyright © 2015 John Wiley & Sons, Ltd. Source
Bakrim A.,University Pierre and Marie Curie |
Bakrim A.,University Hassan I |
Ngunjiri J.,FloraFauna Oil Ltd |
Crouzet S.,University Pierre and Marie Curie |
And 5 more authors.
Natural Product Communications | Year: 2014
Phytoecdysteroids are plant analogues of insect moulting hormones and are used by plants to repel or disturb phytophagous insects. They are also active on mammals and present in many plants used in traditional medicine. The Ajuga genus contains several such species, which occur in various pharmacopoeias. We report the isolation and identification of major and minor ecdysteroids present in two Ajuga species, A. iva and A. remota, both of which are used as medicinal plants in Africa. Three minor ecdysteroids (abutasterone, ponasterone A and sidisterone) have been found for the first time in the Ajuga genus. Source