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Bellevue, WA, United States

Ando T.,Innovative Healthcare
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference | Year: 2011

Patients with diseases such as chronic obstructive pulmonary disease (COPD) need to improve their thorax mobility. Thoracic ROM is one of the simplest and most useful indexes to evaluate the respiratory function. In this paper, we have proposed the prototype of a simple thoracic ROM measurement system with real-time visual bio-feedback in the chest expansion test. In this system, the thoracic ROM is measured using a wire-type linear encoder whose wire is wrapped around the thorax. In this paper, firstly, the repeatability and reliability of measured thoracic ROM was confirmed as a first report of the developed prototype. Secondly, we analyzed the effect of the bio-feedback system on the respiratory function. The result of the experiment showed that it was easier to maintain a large and stable thoracic ROM during deep breathing by using the real-time visual biofeedback system of the thoracic ROM.

Innovative Healthcare | Date: 2015-10-30

Occlusive tissue dressings and methods including an elastomeric drape and a liquid component, at least partially cross-linked at least after one of drying and curing, suitable for application at a dressing-to-skin interface in order to create a substantially air-tight seal. The same or a different liquid component may be applied by a user at a tube-to-dressing interface in order to create a similar air-tight seal around the tube, if not occlusively sealed during its manufacture.

In an embodiment, a first communication that is an electronic hospital census and/or an outpatient authorization report is received by a control device operated by an entity that is a different entity than the hospital. The first communication identifies an individual admitted to a hospital and/or individual scheduled for an elective outpatient procedure. The control device stores a file for the patient identifying a service needed by the patient, and the service is a pre-procedure service, a post-procedure service, a pre-discharge service, and/or a post-discharge service. The entity that operates the control device performs a second communication that coordinates the service from a provider that is a different entity than the entity that operates the control device. The second communication is performed at a time that is at least one of before admission to the hospital, at admission to the hospital, before the procedure, after the procedure, or at discharge.

Lee S.W.,Innovative Healthcare | Lee S.W.,Harvard University | Eddington D.K.,Massachusetts Eye and Ear Infirmary | Eddington D.K.,Harvard University | And 2 more authors.
Journal of Neurophysiology | Year: 2013

In working to improve the quality of visual percepts elicited by retinal prosthetics, considerable effort has been made to understand how retinal neurons respond to electric stimulation. Whereas responses arising from direct activation of retinal ganglion cells have been well studied, responses arising through indirect activation (e.g., secondary to activation of bipolar cells) are not as well understood. Here, we used cell-attached, patchclamp recordings to measure the responses of rabbit ganglion cells in vitro to a wide range of stimulus-pulse parameters (amplitudes: 0-100 μA; durations: 0.1-50 ms), applied to a 400-μm-diameter, subretinalstimulating electrode. The indirect responses generally consisted of multiple action potentials that were clustered into bursts, although the latency and number of spikes within a burst were highly variable. When different parameter pairs representing identical charge levels were compared, the shortest pulse durations generally elicited the most spikes. In addition, latencies were shortest, and jitter was lowest for short pulses. These findings suggest that short pulses are optimum for activation of presynaptic neurons, and therefore, short pulses are more effective for both direct as well as indirect activation. © 2013 the American Physiological Society.

Jensen R.J.,Innovative Healthcare | Rizzo III J.F.,Innovative Healthcare | Rizzo III J.F.,Massachusetts Eye and Ear Infirmary
Journal of Neural Engineering | Year: 2011

An electronic retinal prosthesis may provide useful vision for patients suffering from retinitis pigmentosa (RP). In animal models of RP, the amount of current needed to activate retinal ganglion cells (RGCs) is higher than in normal, healthy retinas. In this study, we sought to reduce the stimulation thresholds of RGCs in a degenerate rat model (P23H-line 1) by blocking GABA receptor mediated inhibition in the retina. We examined the effects of TPMPA, a GABA C receptor antagonist, and SR95531, a GABA A receptor antagonist, on the electrically evoked responses of RGCs to biphasic current pulses delivered to the subretinal surface through a 400 μm diameter electrode. Both TPMPA and SR95531 reduced the stimulation thresholds of ON-center RGCs on average by 15% and 20% respectively. Co-application of the two GABA receptor antagonists had the greatest effect, on average reducing stimulation thresholds by 32%. In addition, co-application of the two GABA receptor antagonists increased the magnitude of the electrically evoked responses on average three-fold. Neither TPMPA nor SR95531, applied alone or in combination, had consistent effects on the stimulation thresholds of OFF-center RGCs. We suggest that the effects of the GABA receptor antagonists on ON-center RGCs may be attributable to blockage of GABA receptors on the axon terminals of ON bipolar cells. © 2011 IOP Publishing Ltd.

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