INMED

Marseille, France
Marseille, France
SEARCH FILTERS
Time filter
Source Type

News Article | July 27, 2017
Site: www.prnewswire.com

The study results suggest that peripheral application of cannabinoids targeting the natural endocannabinoid receptor system (in this case, receptor CB1) may provide a valuable approach in treating severe pain.  The model utilized in this study mimics muscle pain reported by sufferers of temporomandibular disorders (TMD) that affect the jaw muscles and joint.  TMD is a chronic pain condition that is difficult to treat with current pain-relieving medications and more commonly affects women than men. "Developing a topically-applied product that can provide localized relief of chronic and/or acute severe pain, without central side effects, remains one of the 'holy grails' in the field of analgesia", said Dr. Sazzad Hossain, CSO of InMed.  "This study sets the stage for advanced work in various pain models to explore the role of several cannabinoid compounds, applied as topical agents, to target the CB1 and other pain-related receptors." Use of InMed's proprietary bioinformatics database assessment tool has led to the identification of several individual cannabinoid compounds, or combinations thereof, to specifically address both chronic and acute pain in a topically-applied product.  "InMed's internal targeting capabilities, linking specific cannabinoids to diseases with a high unmet medical need, remains a fundamental component to our ongoing success in validating the role of this class of compounds in a wide range of diseases", added Dr. Hossain. For additional information, please follow this link to the article:  http://onlinelibrary.wiley.com/doi/10.1002/ejp.1085/full Mitacs Elevate helps organizations develop their research & development management capacity in-house with a minimal impact on their R&D budgets. By connecting companies with a talented PhD graduates, the two-year research project encourages knowledge transfer of the fellow's practical and professional skills to the organization. These collaborations help build research and development management capacity and companies benefit from fellows' creativity and fresh approach to current research challenges. InMed is a preclinical stage biopharmaceutical company specializing in the research and development of novel, cannabinoid-based prescription drug therapies utilizing novel drug delivery systems. InMed conducts research, discovery, preclinical, clinical, regulatory, manufacturing and commercial development activities for its product candidates. InMed's proprietary bioinformatics database assessment tool, the biosynthesis manufacturing process and its drug development programs are the fundamental value drivers of the Company. For more information, visit www.inmedpharma.com. This news release contains "forward-looking information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning of applicable securities laws.  Forward-looking information is based on management's current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements.  Forward-looking information in this news release includes statements about: that peripheral or topical application of cannabinoids targeting the natural endocannabinoid receptor system (in this case, receptor CB1) provides a valuable approach in treating chronic and/or acute severe pain without central side effects, InMed's proprietary bioinformatics database assessment tool, linking specific cannabinoids to diseases with a high unmet medical need, being able to validate the role of this class of compounds in a wide range of diseases, and the expected fundamental value drivers of the Company. With respect to the forward-looking information contained in this news release, InMed has made numerous assumptions regarding, among other things: demand for InMed's products; and continued economic and market stability. While InMed considers these assumptions to be reasonable, these assumptions are inherently subject to significant business, economic, competitive, market and social uncertainties and contingencies. Additionally, there are known and unknown risk factors which could cause InMed's actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information contained herein.  Known risk factors include, among others: that peripheral or topical application of cannabinoids, identified by InMed's proprietary bioinformatics database assessment tool, will be able to effectively target the natural endocannabinoid receptor system (in this case, receptor CB1) which will provide a valuable approach in treating chronic and/or acute severe pain without central side effects; InMed's proprietary platform technology, product pipeline and drug development programs may not return their expected level of value. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed's Annual Information Form and other continuous disclosure filed with Canadian securities regulatory authorities on SEDAR at www.sedar.com. In addition, readers should review the disclosure under the heading "Risk Factors" in the Final Prospectus, once filed. All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law. NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.


News Article | July 10, 2017
Site: www.prnewswire.com

Under the terms of the agreement, ATERA will develop 3D human skin models of Epidermolysis Bullosa ('EB') to evaluate the in vitro drug efficacy of InMed's lead compound, INM-750, a proprietary, topical cannabinoid product candidate targeted as a therapy in EB and other potential dermatological and wound-healing applications. ATERA will also investigate the beneficial effects of topically applied INM-750 at ultra-structural cellular and molecular levels on in vitro 3D reconstructed human full thickness (dermis-epidermis) skin models composed of both normal and EB-derived skin cells. "INM-750 has demonstrated significant potential in pre-clinical models to address symptomatic improvement of EB including accelerated wound healing and a reduction in pain, itch and inflammation.  This project with ATERA is designed to assess the potential of INM-750 to have an impact in disease reversal, further supporting our current data indicating an up-regulation in specific keratins in the skin", stated Dr. Sazzad Hossain, CSO of InMed. "By utilizing full-thickness skin models derived from EB skin samples, we can better validate INM-750's target effect and efficacy in vitro ahead of our upcoming clinical trial program." "Producing 3D human tissue models of specific diseases in a controlled, reproducible fashion provides a unique tool for drug development screening", says Bart De Wever, CEO of ATERA. "Our core technology enables the development of 3D human skin models engineered of cells from EB patient biopsies that will help InMed investigate the mode-of-action of its lead compound INM-750." About ATERA ATERA SAS (Villeneuve Loubet, France) is a tissue-engineering company specialized in the development, validation, manufacturing and commercialization of advanced human tissue models as reliable, cost-effective, high-quality and more conscientious alternatives for animal experimentation in product evaluation, industrial safety and efficacy as well as medical research. For more information, visit http://www.ateralabs.com About InMed  InMed is a preclinical stage biopharmaceutical company specializing in the research and development of novel, cannabinoid-based prescription drug therapies utilizing novel drug delivery systems. InMed conducts research, discovery, preclinical, clinical, regulatory, manufacturing and commercial development activities for its product candidates. InMed's proprietary bioinformatics database assessment tool, the biosynthesis manufacturing process and its drug development programs are the fundamental value drivers of the Company. This news release contains "forward-looking information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning of applicable securities laws.  Forward-looking information is based on management's current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements.  Forward-looking information in this news release includes statements about: the final formulation for INM-750 being used for IND-enabling pharmacology and toxicology studies and subsequent clinical trials and the expected fundamental value drivers of the Company. With respect to the forward-looking information contained in this news release, InMed has made numerous assumptions regarding, among other things: the importance of pre-clinical data in determining the potential role of INM-750 in treating patients with epidermolysis bullosa; the reliability of data generated using Atera's 3D skin model; and others. While InMed considers these assumptions to be reasonable, these assumptions are inherently subject to significant business, economic, competitive, market and social uncertainties and contingencies. Additionally, there are known and unknown risk factors which could cause InMed's actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information contained herein. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed's Annual Information Form and other continuous disclosure filed with Canadian securities regulatory authorities on SEDAR at www.sedar.com. In addition, readers should review the disclosure under the heading "Risk Factors" in the Final Prospectus, once filed. All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law. NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.


Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss. Worldwide, it is the second-leading cause of blindness, and the current global market for drug therapies to treat glaucoma exceeds US$5 billion.  Risk factors for glaucoma include increased pressure in the eye, a family history of the condition, migraines, high blood pressure, and obesity. Investigators studying patient adherence to glaucoma medications have identified multiple factors related to poor adherence, including more frequent and complex dosing regimens. InMed is developing a stimulus-responsive, nanoparticle-laden vehicle for controlled delivery of ophthalmic drugs into the aqueous humor of the eye. The first applications of this vehicle will be for INM-085 as a cannabinoid-based topical therapy to reduce the intraocular pressure associated with glaucoma. INM-085 is intended for application as a once-per-day eye drop administered immediately prior to the patient's bedtime, intending to assist in reducing the high rate of non-adherence with current glaucoma therapies.  Additionally, this novel, proprietary delivery system for ophthalmic drugs may also play an important role in enabling other companies' proprietary ophthalmic drug candidates or re-invigorating the commercial potential of off-patent products that would benefit from a once-a-day dosing regimen. InMed plans to initiate discussion with potential partners to this end. InMed is a pre-clinical stage biopharmaceutical company that specializes in developing novel therapies through the research and development into the extensive pharmacology of cannabinoids coupled with innovative drug delivery systems. InMed's proprietary bioinformatics database drug/disease targeting tool, cannabinoid biosynthesis technology and drug development pipeline are the fundamental value drivers of the Company. For more information, visit www.inmedpharma.com This news release contains "forward-looking information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning of applicable securities laws.  Forward-looking information is based on management's current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements.  Forward-looking information in this news release includes statements about the potential of cannabinoid compounds to modulate diseases such as glaucoma and other diseases; the potential for this patent application to provide any intellectual property protection for InMed; developing a vehicle for controlled delivery of ophthalmic drugs into the eye; the potential of INM-085 to assist in reducing the high rate of non-adherence with current glaucoma therapies; the potential to out-license InMed's delivery vehicle to other companies with ophthalmic drugs; the ability to re-invigorate the commercial potential of off-patent products; initiating discussions with potential partners; and the expected fundamental value drivers of the company. With respect to the forward-looking information contained in this news release, InMed has made numerous assumptions regarding, among other things: regulatory approval, including patent approval; the effectiveness of the delivery vehicle; demand for InMed's products; and continued economic and market stability. While InMed considers these assumptions to be reasonable, these assumptions are inherently subject to significant business, economic, competitive, market and social uncertainties and contingencies. Additionally, there are known and unknown risk factors which could cause InMed's actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information contained herein.  Known risk factors include, among others: the provisional patent application may not be approved; the delivery vehicle and INM-085 may not produce their desired results; technological challenges associated with developing InMed's proprietary platform technology, including its bioinformatics database drug/disease targeting tool, its cannabinoid biosynthesis technology, and its drug product candidates which may not, individually and in aggregate, return their expected level of value; InMed may not be able to find suitable partners; and economic or market conditions may worsen. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed's Annual Information Form dated March 24, 2017 and its other continuous disclosure documents filed with the Canadian securities regulatory authorities at www.sedar.com. All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law. NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.


News Article | June 13, 2017
Site: www.prnewswire.com

"This agreement with Pharmaseed now adds one of Israel's leading formulation development teams to our efforts and represents an important strategic relationship as we move INM-750 towards our first clinical trial," stated Eric A. Adams, CEO of InMed. Under the agreement, Pharmaseed will develop a final formulation for INM-750 for continued R&D including IND-enabling pharmacology and toxicology studies and subsequent clinical studies. Also included under the scope of the contract is the development of assay methods for manufacturing, stability, quality assurance and other analytical methods. Pharmaseed is Israel's largest GLP private research organization leading in the development of life-science early stage technologies from discovery to the first in man/patient stage. The company specializes in both efficacy proof-of-concept studies and safety evaluation in various animal models, as well as complementary formulation development and in vitro/ex-vivo services. Its core competence lies in the area of translational and regenerative medical projects with main expertise in: Stem Cell, CNS, Pain, Cancer, Angiogenesis, Inflammation, Dermatology, Metabolic disorders, Infectious diseases and Medical devices. Over 50% (40) of the company's employee have PhD degrees representing many years of experience in academic and applied scientific research activity. InMed is a preclinical stage biopharmaceutical company specializing in the research and development of novel, cannabinoid-based prescription drug therapies utilizing novel drug delivery systems. InMed conducts research, discovery, preclinical, clinical, regulatory, manufacturing and commercial development activities for its product candidates. InMed's proprietary bioinformatics database assessment tool, the biosynthesis manufacturing process and its drug development programs are the fundamental value drivers of the Company. For more information, visit www.inmedpharma.com. This news release contains "forward-looking information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning of applicable securities laws.  Forward-looking information is based on management's current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements.  Forward-looking information in this news release includes statements about: the final formulation for INM-750 being used for IND-enabling pharmacology and toxicology studies and subsequent clinical trials and the expected fundamental value drivers of the Company. With respect to the forward-looking information contained in this news release, InMed has made numerous assumptions regarding, among other things: demand for InMed's products; and continued economic and market stability. While InMed considers these assumptions to be reasonable, these assumptions are inherently subject to significant business, economic, competitive, market and social uncertainties and contingencies. Additionally, there are known and unknown risk factors which could cause InMed's actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information contained herein.  Known risk factors include, among others: a formulation for INM-750 that is suitable for advancing it to IND-enabling pharmacology and toxicology studies and subsequent clinical trials may not be attainable; InMed's proprietary platform technology, product pipeline and drug development programs may not return their expected level of value. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed's Annual Information Form and other continuous disclosure filed with Canadian securities regulatory authorities on SEDAR at www.sedar.com. In addition, readers should review the disclosure under the heading "Risk Factors" in the Final Prospectus, once filed. All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law. NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.


News Article | February 15, 2017
Site: www.prweb.com

The continuing medical education program[1] at the AutismOne 2017 Conference in Colorado Springs, Colorado, will offer 23+ CME credits and feature Robert F. Kennedy, Jr. Robert F. Kennedy, Jr., who was asked by President Donald J. Trump to chair a commission on Vaccine Safety and Scientific Integrity, will be presenting on the risks of mercury in medicine. The CME program will address physicians, nurses, and additional healthcare professionals. Mr. Kennedy authored the book titled Thimerosal: Let the Science Speak (Skyhorse Publishing, 2014), with an introduction by Harvard University/Massachusetts General Hospital pediatric neurologist Martha Herbert, MD, PhD, also an AutismOne CME program presenter. The CME activity, which is targeted toward integrative pediatricians and other healthcare providers who serve those with special needs diagnoses and chronic conditions, is directed by Shawn K. Centers, DO, FACOP. Dr. Centers served as medical director at the clinic of heralded osteopath Dr. Viola Frymann for nearly two decades until opening his new medical practice called The Children’s HOPE Center in San Diego, California, this month. He serves as the Chair of the American Board of Integrative Pediatrics. Dr. Centers will speak during the CME and general conference portions of the event, as will Mr. Kennedy and Dr. Herbert. Speaking with Dr. Centers during the general conference portion will be JoQueta Handy, PhD, SLP-CCC, a credentialed speech-language pathologist with a doctorate in integrative medicine. Dr. Handy will speak on the balanced brain biochemistry and the sensory, educational, and therapeutic strategies needed to optimize learning and success for students with special needs diagnoses. Dr. Handy’s school, the Brilliant Learning School, is located in Irvine, California. The American Association of Integrative Medicine collaborates with AutismOne in the availability of this program, offering the Board Certified in Integrative Pediatrics (BCIP) credential. Experienced, treating clinicians who wish to apply for the BCIP credential can apply on-site with AAIM at the AutismOne 2017 Conference CME program. The AutismOne 2017 Conference, which is being held May 24-28, 2017, at the Hotel Elegante Conference & Event Center in beautiful Colorado Springs, Colorado, offers over 100 presenters. The continuing medical education program spans May 25-27 and includes over 40 speakers. For more information about the CME program[1], please visit http://www.autismone.org/CME-Program-for-Professionals-Autismone-Conference-2017. To register for the conference (basic registration currently $59; additional fees apply to CME program), please visit http://www.autismone.org/content/conference-membership-registration. Notes: [1] Joint-Provided: This activity has been planned and implemented in accordance with the Essential Areas and policies of the Missouri State Medical Association/Accreditation Council for Continuing Medical Education through the joint providership of Institute for International Medicine (INMED) and Autism International Association (DBA AutismOne). Physicians: Institute for International Medicine is accredited by the Missouri State Medical Association/Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Institute for International Medicine designates this live activity for a maximum of 23.75 AMA PRA Category 1 Credit(s)ᵀᴹ. Physicians should only claim credit commensurate with the extent of the participation in the activity.


News Article | March 2, 2017
Site: www.accesswire.com

VANCOUVER, BC / ACCESSWIRE / March 2, 2017 / InMed Pharmaceuticals, Inc. ("InMed") (CNSX: IN; OTCQB: IMLFF), a biopharmaceutical company specializing in the research and development of novel, cannabinoid-based drug therapies, today announced the filing of an international Patent Cooperation Treaty (PCT) application, an important component in providing intellectual and commercial protection for INM-750 as a cannabinoid-based topical therapy for Epidermolysis Bullosa Simplex (EBS). Epidermolysis Bullosa (EB) is a group of inherited connective tissue diseases that share a common manifestation of extremely fragile skin that blisters or tears from friction or trauma. Internal organs and bodily systems can also be affected by EB. It results from a defect of anchoring between the dermis and epidermis caused most frequently by the dysfunction or absence of certain proteins, called keratins, in the skin. EB is an orphan disease with no known treatment and has a significant unmet medical need. INM-750 will be the first therapy developed for EB designed specifically to modulate disease activity and to alleviate symptoms. It is well documented that cannabinoid compounds have unique anti-inflammatory, analgesic and wound healing promoting properties via several mechanisms, thus making them theoretically excellent candidates for use in alleviating some of the symptoms associated with EB. InMed's proprietary Bioinformatics Database Assessment Tool predicted a dual approach that may prove beneficial to patients: first, the ability of certain cannabinoids to play a role in addressing key disease hallmarks (wound healing, infection, pain, itch, inflammation) in patients with EB; and second, the ability of some cannabinoids to regulate the expression of various keratins that might compensate for the dysfunctional keratins that cause Epidermolysis Bullosa Simplex (EBS). EBS accounts for the vast majority of EB patients. InMed conducted several in vitro and in vivo assays and the results of these studies form the basis of this PCT application. The Patent Cooperation Treaty (PCT) is an international patent law treaty, which provides a unified procedure for filing patent applications to protect inventions in each of its member states. There are 151 member countries within the PCT worldwide, so near global patent coverage can be obtained through successful patent prosecution in the U.S., Japan, Europe, Canada, Australia, New Zealand, China, Brazil, Russia, India, and many other countries. The original priority date for this filing was May 26, 2015, therefore coverage of any underlying patent claims would extend for 20 years until 2035 in the United States, and may be subject to patent term extensions that would enable years of additional protection. "This is a significant milestone achieved by our scientific team's discovery and validation of a new cannabinoid therapy to treat a serious disease with high unmet medical need. We are looking forward to fully understanding the potential impact of INM-750 in helping the EB community," said Dr. Sazzad Hossain, Chief Scientific Officer of InMed Pharmaceuticals. "The pre-clinical data emerging on the use of cannabinoids for EB, as well as other disease targets in our drug development portfolio, continue to validate our discovery approach using our bioinformatics assessment tool. These drug/disease targeting predictions are then followed by relatively quick, inexpensive, yet highly informative confirmatory laboratory studies to validate the predictions of the database. This approach is proving to be an important means to shorten drug development timelines as well as significantly reduce development costs." InMed is a pre-clinical stage biopharmaceutical company that specializes in developing novel therapies through the research and development into the extensive pharmacology of cannabinoids coupled with innovative drug delivery systems. InMed's proprietary bioinformatics database drug/disease targeting tool, cannabinoid biosynthesis technology and drug development pipeline are the fundamental value drivers of the Company. For more information, visit www.inmedpharma.com This news release contains "forward-looking information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning of applicable securities laws. Forward-looking information is based on management's current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Forward-looking information in this news release includes statements about the potential of cannabinoid compounds to modulate disease activity and to alleviate symptoms in EB and other diseases, the potential for this patent application to provide any intellectual property protection for InMed and the expected fundamental value drivers of the company. Although such statements are based on management's reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Known risk factors include, among others: InMed may not use net proceeds received from the private placement as currently contemplated and InMed's proprietary platform technology, product pipeline and accelerated development pathway may not return their expected level of value. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed's continuous disclosure filings with Canadian securities regulatory authorities at www.sedar.com. All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law. NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.


News Article | March 2, 2017
Site: marketersmedia.com

VANCOUVER, BC / ACCESSWIRE / March 2, 2017 / InMed Pharmaceuticals, Inc. ("InMed") (CNSX: IN; OTCQB: IMLFF), a biopharmaceutical company specializing in the research and development of novel, cannabinoid-based drug therapies, today announced the filing of an international Patent Cooperation Treaty (PCT) application, an important component in providing intellectual and commercial protection for INM-750 as a cannabinoid-based topical therapy for Epidermolysis Bullosa Simplex (EBS). Epidermolysis Bullosa (EB) is a group of inherited connective tissue diseases that share a common manifestation of extremely fragile skin that blisters or tears from friction or trauma. Internal organs and bodily systems can also be affected by EB. It results from a defect of anchoring between the dermis and epidermis caused most frequently by the dysfunction or absence of certain proteins, called keratins, in the skin. EB is an orphan disease with no known treatment and has a significant unmet medical need. INM-750 will be the first therapy developed for EB designed specifically to modulate disease activity and to alleviate symptoms. It is well documented that cannabinoid compounds have unique anti-inflammatory, analgesic and wound healing promoting properties via several mechanisms, thus making them theoretically excellent candidates for use in alleviating some of the symptoms associated with EB. InMed's proprietary Bioinformatics Database Assessment Tool predicted a dual approach that may prove beneficial to patients: first, the ability of certain cannabinoids to play a role in addressing key disease hallmarks (wound healing, infection, pain, itch, inflammation) in all patients with EB; and second, the ability of some cannabinoids to regulate the expression of various keratins that might compensate for the dysfunctional keratins that cause Epidermolysis Bullosa Simplex (EBS). EBS accounts for the vast majority of EB patients. InMed conducted several in vitro and in vivo assays and the results of these studies form the basis of this PCT application. The Patent Cooperation Treaty (PCT) is an international patent law treaty, which provides a unified procedure for filing patent applications to protect inventions in each of its member states. There are 151 member countries within the PCT worldwide, so near global patent coverage can be obtained through successful patent prosecution in the U.S., Japan, Europe, Canada, Australia, New Zealand, China, Brazil, Russia, India, and many other countries. The original priority date for this filing was May 26, 2015, therefore coverage of any underlying patent claims would extend for 20 years until 2035 in the United States, and may be subject to patent term extensions that would enable years of additional protection. "This is a significant milestone achieved by our scientific team's discovery and validation of a new cannabinoid therapy to treat a serious disease with high unmet medical need. We are looking forward to fully understanding the potential impact of INM-750 in helping the EB community," said Dr. Sazzad Hossain, Chief Scientific Officer of InMed Pharmaceuticals. "The pre-clinical data emerging on the use of cannabinoids for EB, as well as other disease targets in our drug development portfolio, continue to validate our discovery approach using our bioinformatics assessment tool. These drug/disease targeting predictions are then followed by relatively quick, inexpensive, yet highly informative confirmatory laboratory studies to validate the predictions of the database. This approach is proving to be an important means to shorten drug development timelines as well as significantly reduce development costs." InMed is a pre-clinical stage biopharmaceutical company that specializes in developing novel therapies through the research and development into the extensive pharmacology of cannabinoids coupled with innovative drug delivery systems. InMed's proprietary bioinformatics database drug/disease targeting tool, cannabinoid biosynthesis technology and drug development pipeline are the fundamental value drivers of the Company. For more information, visit www.inmedpharma.com This news release contains "forward-looking information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning of applicable securities laws. Forward-looking information is based on management's current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Forward-looking information in this news release includes statements about the potential of cannabinoid compounds to modulate disease activity and to alleviate symptoms in EB and other diseases, the potential for this patent application to provide any intellectual property protection for InMed and the expected fundamental value drivers of the company. Although such statements are based on management's reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Known risk factors include, among others: InMed may not use net proceeds received from the private placement as currently contemplated and InMed's proprietary platform technology, product pipeline and accelerated development pathway may not return their expected level of value. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed's continuous disclosure filings with Canadian securities regulatory authorities at www.sedar.com. All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law. NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE. VANCOUVER, BC / ACCESSWIRE / March 2, 2017 / InMed Pharmaceuticals, Inc. ("InMed") (CNSX: IN; OTCQB: IMLFF), a biopharmaceutical company specializing in the research and development of novel, cannabinoid-based drug therapies, today announced the filing of an international Patent Cooperation Treaty (PCT) application, an important component in providing intellectual and commercial protection for INM-750 as a cannabinoid-based topical therapy for Epidermolysis Bullosa Simplex (EBS). Epidermolysis Bullosa (EB) is a group of inherited connective tissue diseases that share a common manifestation of extremely fragile skin that blisters or tears from friction or trauma. Internal organs and bodily systems can also be affected by EB. It results from a defect of anchoring between the dermis and epidermis caused most frequently by the dysfunction or absence of certain proteins, called keratins, in the skin. EB is an orphan disease with no known treatment and has a significant unmet medical need. INM-750 will be the first therapy developed for EB designed specifically to modulate disease activity and to alleviate symptoms. It is well documented that cannabinoid compounds have unique anti-inflammatory, analgesic and wound healing promoting properties via several mechanisms, thus making them theoretically excellent candidates for use in alleviating some of the symptoms associated with EB. InMed's proprietary Bioinformatics Database Assessment Tool predicted a dual approach that may prove beneficial to patients: first, the ability of certain cannabinoids to play a role in addressing key disease hallmarks (wound healing, infection, pain, itch, inflammation) in all patients with EB; and second, the ability of some cannabinoids to regulate the expression of various keratins that might compensate for the dysfunctional keratins that cause Epidermolysis Bullosa Simplex (EBS). EBS accounts for the vast majority of EB patients. InMed conducted several in vitro and in vivo assays and the results of these studies form the basis of this PCT application. The Patent Cooperation Treaty (PCT) is an international patent law treaty, which provides a unified procedure for filing patent applications to protect inventions in each of its member states. There are 151 member countries within the PCT worldwide, so near global patent coverage can be obtained through successful patent prosecution in the U.S., Japan, Europe, Canada, Australia, New Zealand, China, Brazil, Russia, India, and many other countries. The original priority date for this filing was May 26, 2015, therefore coverage of any underlying patent claims would extend for 20 years until 2035 in the United States, and may be subject to patent term extensions that would enable years of additional protection. "This is a significant milestone achieved by our scientific team's discovery and validation of a new cannabinoid therapy to treat a serious disease with high unmet medical need. We are looking forward to fully understanding the potential impact of INM-750 in helping the EB community," said Dr. Sazzad Hossain, Chief Scientific Officer of InMed Pharmaceuticals. "The pre-clinical data emerging on the use of cannabinoids for EB, as well as other disease targets in our drug development portfolio, continue to validate our discovery approach using our bioinformatics assessment tool. These drug/disease targeting predictions are then followed by relatively quick, inexpensive, yet highly informative confirmatory laboratory studies to validate the predictions of the database. This approach is proving to be an important means to shorten drug development timelines as well as significantly reduce development costs." InMed is a pre-clinical stage biopharmaceutical company that specializes in developing novel therapies through the research and development into the extensive pharmacology of cannabinoids coupled with innovative drug delivery systems. InMed's proprietary bioinformatics database drug/disease targeting tool, cannabinoid biosynthesis technology and drug development pipeline are the fundamental value drivers of the Company. For more information, visit www.inmedpharma.com This news release contains "forward-looking information" and "forward-looking statements" (collectively, "forward-looking information") within the meaning of applicable securities laws. Forward-looking information is based on management's current expectations and beliefs and is subject to a number of risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. Forward-looking information in this news release includes statements about the potential of cannabinoid compounds to modulate disease activity and to alleviate symptoms in EB and other diseases, the potential for this patent application to provide any intellectual property protection for InMed and the expected fundamental value drivers of the company. Although such statements are based on management's reasonable assumptions, there can be no assurance that such assumptions will prove to be correct. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements. Known risk factors include, among others: InMed may not use net proceeds received from the private placement as currently contemplated and InMed's proprietary platform technology, product pipeline and accelerated development pathway may not return their expected level of value. A more complete discussion of the risks and uncertainties facing InMed is disclosed in InMed's continuous disclosure filings with Canadian securities regulatory authorities at www.sedar.com. All forward-looking information herein is qualified in its entirety by this cautionary statement, and InMed disclaims any obligation to revise or update any such forward-looking information or to publicly announce the result of any revisions to any of the forward-looking information contained herein to reflect future results, events or developments, except as required by law. NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.


News Article | December 15, 2016
Site: www.prnewswire.com

VANCOUVER, Dec. 15, 2016 /PRNewswire/ - InMed Pharmaceuticals Inc. ("InMed" or "the Company") (CSE: IN; OTCQB: IMLFF), a biopharmaceutical company specializing in the research and development of novel, cannabinoid-based therapies combined with innovative drug delivery systems, announced...


News Article | February 27, 2017
Site: www.prnewswire.com

CSE: INOTCQB: IMLFF VANCOUVER, Feb. 27, 2017 /PRNewswire/ - InMed Pharmaceuticals, Inc. ("InMed") (CSE: IN; OTCQB: IMLFF), reported today that prior to their expiry on Friday, February 24, 2017 a total of 10,672,750 common share purchase warrants have been exercised at a price of...


CSE: IN OTCQB: IMLFF VANCOUVER, Oct. 31, 2016 /PRNewswire/ - InMed Pharmaceuticals, Inc. ("InMed") (CSE: IN; OTCQB: IMLFF), today announced the appointment of Alexandra D.J. Mancini, M.Sc., as Senior Vice President, Clinical and Regulatory Affairs. "Ms. Mancini has over 30 years'...

Loading INMED collaborators
Loading INMED collaborators