Kimhae, South Korea
Kimhae, South Korea

Inje University is a private university founded in 1932, located in Gimhae, Korea. As of Aug, 2009, it had 874 faculty members, 230 staff members, 14,373 Undergraduate students and 1,458 Graduate students. The University has 6 colleges and 5 graduate schools. The founding mission is to save the world through love and virtue. The educational goals are: to preserve nature; to value human lives and philanthropy. The school precepts are honesty, sincerity, and diligence. Wikipedia.

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The present description relates to a dysphagia rehabilitation apparatus to help tongue muscle rehabilitation exercise during dysphagia rehabilitation. More particularly, it relates to a device that when a patient wearing the dysphagia rehabilitation device contacts the tongue to a position sensing unit configured on the front of a mask, a sensing single according to a change of a physical value of resistance corresponding to the tongues touching position from the position sensing unit. Then a control unit of a remote device generates a control signal through the transmitted sensing signal, thereby the remote device controls rehabilitation, games and programs of similar functions thereof and induce patients interest of rehabilitation. Thus, effect of rehabilitation is improved.

Myung Y.S.,Inje University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2013

We revisit the classical stability of the Schwarzschild black hole in fourth-order theories of gravity. Contrary to the stability of this black hole, it turns out that the linearized perturbations exhibit unstable modes featuring the Gregory-Laflamme instability of the five-dimensional black string. This shows clearly an instability of the black hole in fourth-order gravity with α=-β/3. © 2013 American Physical Society.

Myung Y.S.,Inje University
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2014

We analyze the classical stability of Schwarzschild black hole in massive conformal gravity which was recently proposed for another massive gravity model. This model in the Jordan frame is conformally equivalent to the Einstein-Weyl gravity in the Einstein frame. The coupled linearized Einstein equation is decomposed into the traceless and trace equation when one chooses 6m2φ=δR. Solving the traceless equation exhibits unstable modes featuring the Gregory-Laflamme s-mode instability of five-dimensional black string, while we find no unstable modes when solving the trace equation. It is shown that the instability of the black hole in massive conformal gravity arises from the massiveness where the geometry of extra dimension trades for mass. © 2014 The Author.

Lee S.R.,Inje University
Pflügers Archiv : European journal of physiology | Year: 2012

Glucocorticoids (GCs) are essential steroid hormones for homeostasis, development, metabolism, and cognition and possess anti-inflammatory and immunosuppressive actions. Since glucocorticoid receptor II (GR) is nearly ubiquitous, chronic activation or depletion of GCs leads to dysfunction of diverse organs, including the heart and blood vessels, resulting predominantly from changes in gene expression. Most studies, therefore, have focused on the genomic effects of GC to understand its related pathophysiological manifestations. The nongenomic effects of GCs clearly differ from well-known genomic effects, with the former responding within several minutes without the need for protein synthesis. There is increasing evidence that the nongenomic actions of GCs influence various physiological functions. To develop a GC-mediated therapeutic target for the treatment of cardiovascular disease, understanding the genomic and nongenomic effects of GC on the cardiovascular system is needed. This article reviews our current understanding of the underlying mechanisms of GCs on cardiovascular diseases and stress, as well as how nongenomic GC signaling contributes to these conditions. We suggest that manipulation of GC action based on both GC and GR metabolism, mitochondrial impact, and the action of serum- and glucocorticoid-dependent kinase 1 may provide new information with which to treat cardiovascular diseases.

Suk S.I.,Inje University
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | Year: 2012

Pedicle screw instrumentation in AIS has advantages of rigid fixation, improved deformity correction and a shorter fusion, but needs an exacting technique. The author has been using the K-wire method with intraoperative single PA and lateral radiographs, because it is safe, accurate and fast. Pedicle screws are inserted in every segment on the correction side (thoracic concave) and every 2-3 on the supportive side (thoracic convex). After an over-bent rod is inserted on the corrective side, the rod is rotated 90° counterclockwise. This maneuver corrects the coronal and sagittal curves. Then the vertebra is derotated by direct vertebral rotation (DVR) correcting the rotational deformity. The direction of DVR should be opposite to that of the vertebral rotation. A rigid rod has to be used to prevent the rod from straightening out during the rod derotation and DVR. The ideal classification of AIS should address all curve patterns, predicts accurate fusion extent and have good inter/intraobserver reliability. The Suk classification matches the ideal classification is simple and memorable, and has only four structural curve patterns; single thoracic, double thoracic, double major and thoracolumbar/lumbar. Each curve has two types, A and B. When using pedicle screws in thoracic AIS, curves are usually fused from upper neutral to lower neutral vertebra. Identification of the end vertebra and the neutral vertebra is important in deciding the fusion levels and the direction of DVR. In lumbar AIS, fusion is performed from upper neutral vertebra to L3 or L4 depending on its curve types. Rod derotation and DVR using pedicle screw instrumentation give true three dimensional deformity correction in the treatment of AIS. Suk classification with these methods predicts exact fusion extent and is easy to understand and remember.

Myung Y.S.,Inje University
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2010

We find the entropy of Kehagias-Sfetsos black hole in the deformed Hořava-Lifshitz gravity by using the first law of thermodynamics. When applying generalized uncertainty principle (GUP) to Schwarzschild black hole, the entropy S = A / 4 + (π / ω) ln (A / 4) may be interpreted as the GUP-inspired black hole entropy. Hence, it implies that the duality in the entropy between the Kehagias-Sfetsos black hole and GUP-inspired Schwarzschild black hole is present. © 2010 Elsevier B.V. All rights reserved.

A pharmaceutical composition for preventing or treating an ocular surface disease is disclosed, wherein the pharmaceutical composition includes, as an active component, collagen type II 1 based peptide GQDGLAGPK isolated from chondrocyte-derived extracellular matrix (CDEM). In an alkaline burn animal mode treated with peptide GQDGLAGPK, the occurrence of corneal opacification is reduced as well as the expression of angiogenic factors (e.g., CD31 and VEGF). In addition, the expression of inflammatory markers (e.g., macrophages, TNF, ICAM-1, VCAM-1, and MMP-9) is reduced while the expression of inflammation-inducing factor (e,g,, NF-B) is suppressed. The peptide GQDGLAGPK according to the present invention may be applied to a pharmaceutical composition for preventing or treating an ocular surface disease (e.g., a corneal disease).

Inje University | Date: 2015-03-11

Provided are a method for culturing peripheral nerve-derived neural crest stem cells including: culturing the peripheral nerve fragments embedded into the hydrogel; and breaking down only the hydrogel to collect neural crest stem cells that have migrated and proliferated in the hydrogel from the peripheral nerve fragments; and amplified and expanded collected neural crest stem cells in monolayer culture conditions. Provided also are a method of differentiating the neural crest stem cells; and a method of manufacturing cell therapeutic agent for the treatment of a neurologic disorder, each including the neural crest stem cells. Neural crest stem cells cultured according to the method have excellent in vitro proliferation capacity, and have the multipotency of being able to be differentiated into cells that constitute the peripheral nervous system and the central nervous system. Accordingly, the neural crest stem cells are suitable for use in the production of new drugs, such as the cell therapeutic agent and the tissue-engineering therapeutic agent, and also tools for cytological, molecular biological fundamental research and the new drug development research.

The present invention relates to a method for preparing a nanostructure by electrochemical deposition, and a nanostructure prepared thereby, and more specifically, to: a method for preparing a nanostructure by electrochemical deposition, wherein it is possible to prepare a nanostructure having remarkable morphological, structural and optical characteristics by controlling a method for applied power during electrochemical deposition; and a nanostructure prepared thereby.

A composition for deriving the maturation of dendritic cells includes complex cytokines generated by the simulation, the expression of which is induced on EBV-infected B cells. The dendritic cell maturation process, which conventionally takes approximately 7 days, can be shortened to 2 days, thereby producing dendritic cells in a more economically advantageous and effective manner.

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