Incheon, South Korea
Incheon, South Korea

Inha University ) is a private research university located in Incheon, South Korea.Known traditionally for research and education in the engineering and physical science, the University was established by the first president of South Korea, Syngman Rhee. It is a Korean-American collaboration school, even in its name: the Morpheme "In" comes from the city of Incheon and "Ha" comes from Hawaii, USA. At first time, it started as a technical college, named Inha Institute of Technology .Currently, Inha is ranked 10th nationwide, and especially 4th in Engineering and Science, by JoongAng Ilbo's annual ranking of South Korean universities. Inha is a member of GU8. Wikipedia.


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Zhang N.,Jiangxi University of Finance and Economics | Choi Y.,Inha University
Renewable and Sustainable Energy Reviews | Year: 2014

Recently, a relatively new methodology named directional distance function (DDF) has been attracting positive attention in the field of energy and environmental (E&E) modeling. However, there is still no literature review on the application of DDF in E&E studies. This paper is intended to fill this gap. First, the most widely used DDF techniques and its extensions are briefly introduced. Second, this article attempts a classification of typical publications in this field. The main issues raised by the previous studies are discussed. Some guidelines for model selection and future directions are proposed for DDF related research in E&E studies. © 2014 Elsevier Ltd.


Cheong W.J.,Inha University
Journal of Separation Science | Year: 2014

It is surprising that there has been no devoted review article for frits and relevant studies so far despite the long history of packed columns and the use of frits in them. This review was activated for such a reason. Both separate frits and in situ permanent frits have been covered since the appearance of primitive frits. The in situ fritting methods such as the formation of organic monoliths, sol-gel technology, sintering, fritless techniques such as tapered tip and capillary restrictors, and miscellaneous fritting techniques including magnetically trapped frits and single particle frits are introduced and discussed. In addition, frit-related studies and patents are also introduced. Finally, some conclusive comments on the choice of fritting technique in different situations and future perspectives are given. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Of all the intracellular organelles, secretory granules contain by far the highest calcium concentration; secretory granules of typical neuroendocrine chromaffin cells contain ∼40 mM Ca2+ and occupy ∼20% cell volume, accounting for >60% of total cellular calcium. They also contain the majority of cellular inositol 1,4,5-trisphosphate receptors (IP3Rs) in addition to the presence of >2 mM of chromogranins A and B that function as high-capacity, low-affinity Ca2+ storage proteins. Chromogranins A and B also interact with the IP3Rs and activate the IP 3R/Ca2+ channels. In experiments with both neuroendocrine PC12 and nonneuroendocrine NIH3T3 cells, in which the number of secretory granules present was changed by either suppression or induction of secretory granule formation, secretory granules were demonstrated to account for >70% of the IP3-induced Ca2+ releases in the cytoplasm. Moreover, the IP3 sensitivity of secretory granule IP3R/Ca 2+ channels is at least ∼6- to 7-fold more sensitive than those of the endoplasmic reticulum, thus enabling secretory granules to release Ca2+ ahead of the endoplasmic reticulum. Further, there is a direct correlation between the number of secretory granules and the IP3 sensitivity of cytoplasmic IP3R/Ca2+ channels and the increased ratio of IP3-induced cytoplasmic Ca2+ release, highlighting the importance of secretory granules in the IP3-dependent Ca2+ signaling. Given that secretory granules are present in all secretory cells, these results presage critical roles of secretory granules in the control of cytoplasmic Ca2+ concentrations in other secretory cells. - Yoo, S. H. Secretory granules in inositol 1,4,5-trisphosphatedependent Ca2+ signaling in the cytoplasm of neuroendocrine cells. © FASEB.


Through micromagnetic simulations, it was found that the spin transfer torque (STT) switching current density is reduced with non-collinear polarizer layer magnetization. The dependence of the switching current density on the polarizer layer magnetization angle was investigated, and a typical magnetic tunneling junction structure with an exchange biased synthetic ferrimagnetic polarizer layers was considered. The easy axis of the polarizer layer was varied through controlling the exchange bias field direction in the ellipse cross-section nano-pillar structures. It was found that the switching current density was reduced by 39% when the exchange bias field was 10° from the long axis of the ellipse without the perpendicular STT. When the effect of the perpendicular STT was included, the switching current reductions were general for the non-collinear polarizer layer. © 2012 American Institute of Physics.


We investigate the dependence of the switching current density on the exchange stiffness constant in the spin transfer torque magnetic tunneling junction using micromagnetic simulations. Since the widely accepted analytic expression of the switching current density is based on the macrospin model, there is no dependence on the exchange stiffness constant. However, we found strong dependence of the switching current density on the exchange stiffness constant because of the formation of complex spin configurations. © 2012 The Japan Society of Applied Physics.


β-Lapachone (β-lap) is a bioreductive agent that is activated by the two-electron reductase NAD(P)H quinone oxidoreductase 1 (NQO1). Although β-lap has been reported to induce apoptosis in various cancer types in an NQO1-dependent manner, the signaling pathways by which β-lap causes apoptosis are poorly understood. β-Lap-induced apoptosis and related molecular signaling pathways in NQO1-negative and NQO1-overexpressing MDA-MB-231 cells were investigated. Pharmacological inhibitors or siRNAs against factors involved in β-lap-induced apoptosis were used to clarify the roles played by such factors in β-lap-activated apoptotic signaling pathways. β-Lap leads to clonogenic cell death and apoptosis in an NQO1-dependent manner. Treatment of NQO1-overexpressing MDA-MB-231 cells with β-lap causes rapid disruption of mitochondrial membrane potential, nuclear translocation of AIF and Endo G from mitochondria, and subsequent caspase-independent apoptotic cell death. siRNAs targeting AIF and Endo G effectively attenuate β-lap-induced clonogenic and apoptotic cell death. Moreover, β-lap induces cleavage of Bax, which accumulates in mitochondria, coinciding with the observed changes in mitochondria membrane potential. Pretreatment with Salubrinal (Sal), an endoplasmic reticulum (ER) stress inhibitor, efficiently attenuates JNK activation caused by β-lap, and subsequent mitochondria-mediated cell death. In addition, β-lap-induced generation and mitochondrial translocation of cleaved Bax are efficiently blocked by JNK inhibition. Our results indicate that β-lap triggers induction of endoplasmic reticulum (ER) stress, thereby leading to JNK activation and mitochondria-mediated apoptosis. The signaling pathways that we revealed in this study may significantly contribute to an improvement of NQO1-directed tumor therapies.


Ansari M.B.,Inha University | Park S.-E.,Inha University
Energy and Environmental Science | Year: 2012

The utilization of CO 2 as a soft oxidant and promoter is a promising concept for industrial applications that could not only contribute to the mitigation of CO 2 levels, but also the development of economical and energy efficient syntheses of various chemicals. The abundant availability, non-toxic, economic and mild oxidizing properties of CO 2 has resulted in immense interest in its use as an oxidant in several reactions, such as the oxidative coupling of CH 4 and the oxidative dehydrogenation of alkanes and alkyl aromatics. At present, only a few processes based on CO 2 as a soft oxidant have been realised on a technical scale in spite of dedicated research. This review is intended to trace the emergence, application and understanding of such systems and shed light on the further development that may lead to industrial scale operations in the near future. © 2012 The Royal Society of Chemistry.


Kang J.S.,Inha University
International orthopaedics | Year: 2013

To observe the natural history of asymptomatic osteonecrosis of the femoral head, and to analyse the associations between the subsequent development of symptoms, epidemiological risk factors and the character of the lesions. Sixty-eight patients were diagnosed with asymptomatic osteonecrosis of the femoral head. The patients were classified based on the development of symptoms. Relations were sought between symptom development and epidemiological risk factors, and the size and location of the necrotic lesions. Thirty-eight patients developed symptoms (55.9%) at a mean 2.27 years after diagnosis. Symptoms developed in 18 of 28 patients with alcohol-related necrosis (64.3%), in eight of 14 patients with steroid-related necrosis (57.1%), and in 12 of 26 patients with idiopathic necrosis (46.2%). None of the following: gender, age, body mass index (BMI), smoking status, or cholesterol level, was found to be significantly associated with the development of symtoms in asymptomatic osteonecrosis of femoral head (ONFH). Duration and amount of exposure to steroid were not significantly associated with symptom development. In the groups of heavy alcohol drinkers, large necrotic lesions and laterally located lesions showed a higher prevalence of symptom development. Symptoms developed in 55.9% of asymptomatic osteonecrosis of the femoral head. Prevalence of symptom development was significantly higher in heavy alcohol drinkers and large-sized lateral lesions.


Patent
University of Southern California and Inha University | Date: 2015-11-06

System and methods for detecting anomalies and identifying faults of a gas turbine engine may include a recorder in communication with a processor. The recorder may be configured to capture archival data of the gas turbine engine. A flight normalizer module may be configured to produce normalized results based on the archival data. A flight parameter features module may be configured to generate flight parameter features based on the normalized results. A data warehouse module may be configured to determine suspected fault classes by comparing the flight parameter features against training parameter features stored in the data warehouse module based on queries from the flight parameter features module. A majority vote module may be configured to determine a diagnosed fault class based on the suspected fault classes.


Patent
University of Southern California and Inha University | Date: 2016-06-22

System and methods for detecting anomalies and identifying faults of a gas turbine engine (10) may include a recorder (86) in communication with a processor (610). The recorder may be configured to capture archival data of the gas turbine engine (10). A flight normalizer module (90) may be configured to produce normalized results based on the archival data (88). A flight parameter features module (108) may be configured to generate flight parameter features based on the normalized results. A data warehouse module (36) may be configured to determine suspected fault classes (113) by comparing the flight parameter features (110) against training parameter features (80) stored in the data warehouse module (36) based on queries from the flight parameter features module (108). A majority vote module (114) may be configured to determine a diagnosed fault class (116) based on the suspected fault classes (113).

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