Infokom GmbH

Neubrandenburg, Germany

Infokom GmbH

Neubrandenburg, Germany
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Takenga C.,Vienna University of Technology | Dworzak M.,Labdia Labordiagnostik GmbH | Dworzak M.,Medical University of Vienna | Diem M.,Vienna University of Technology | And 7 more authors.
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2017

Clinical researchers working in flow cytometry (FCM) nowadays experience increasing demands to perform experiments that involve high throughput, rare event analysis and detailed immunophenotyping. Beckman Coulter and Becton Dickinson offer multi-use flow cytometry sorters that can analyze up to 70K EPS (events per seconds) with more than nine parameters enabled. While this multi-parametric feature provides a great power for hypothesis testing, it also generates a vast amount of data, which is analyzed manually through a processing called gating. For large experiments, this manual gating turns out to be time consuming and requires intensive operator training and experience. The lack of required expertise leads to wrong interpretation of data, thus a wrong therapy course for the case of patients with acute lymphoblastic leukemia (ALL) is followed. This paper aims to present a pipeline-software, as a ready-to-use machine learning based automated FCM assessment tool for the daily clinical practice for patients with ALL. The new system increases accuracy in assessment of FCM based on minimal residual disease (MRD) method in samples analyzed by conventional operator-based gating since computer-aided analysis potentially has a higher power due to the use of the whole multi-parametric FCM-data space at once instead of using methods restricted to two-dimensional decision rules. The tool is implemented as a telemedical network for analysis, clinical follow-up, treatment monitoring of leukemia and allows dissemination of automated FCM-MRD analysis to medical centres in the world. © Springer International Publishing AG 2017.


Takenga C.,Infokom GmbH | Berndt R.-D.,Infokom GmbH | Musongya O.,Baptist Church in Central Africa CBCA | Kitero J.,Baptist Church in Central Africa CBCA | And 6 more authors.
International Journal of Telemedicine and Applications | Year: 2014

The demand for new healthcare services is growing rapidly. Improving accessibility of the African population to diabetes care seems to be a big challenge in most countries where the number of care centers and medical staff is reduced. Information and communication technologies (ICT) have great potential to address some of these challenges faced by several countries in providing accessible, cost-effective, and high-quality health care services. This paper presents the Mobil Diab system which is a telemedical approach proposed for the management of long-term diseases. The system applies modern mobile and web technologies which overcome geographical barriers, and increase access to health care services. The idea of the system is to involve patients in the therapy process and motivate them for an active participation. For validation of the system in African context, a trial was conducted in the Democratic Republic of Congo. 40 Subjects with diabetes divided randomly into control and intervention groups were included in the test. Results show that Mobil Diab is suitable for African countries and presents a number of benefits for the population and public health care system. It improves clinical management and delivery of diabetes care services by enhancing access, quality, motivation, reassurance, efficiency, and cost-effectiveness. © 2014 Claude Takenga et al.


PubMed | Ruwenzori State University, Provincial Health Division DPS, Baptist Church in Central Africa CBCA and Infokom GmbH
Type: | Journal: International journal of telemedicine and applications | Year: 2014

The demand for new healthcare services is growing rapidly. Improving accessibility of the African population to diabetes care seems to be a big challenge in most countries where the number of care centers and medical staff is reduced. Information and communication technologies (ICT) have great potential to address some of these challenges faced by several countries in providing accessible, cost-effective, and high-quality health care services. This paper presents the Mobil Diab system which is a telemedical approach proposed for the management of long-term diseases. The system applies modern mobile and web technologies which overcome geographical barriers, and increase access to health care services. The idea of the system is to involve patients in the therapy process and motivate them for an active participation. For validation of the system in African context, a trial was conducted in the Democratic Republic of Congo. 40 Subjects with diabetes divided randomly into control and intervention groups were included in the test. Results show that Mobil Diab is suitable for African countries and presents a number of benefits for the population and public health care system. It improves clinical management and delivery of diabetes care services by enhancing access, quality, motivation, reassurance, efficiency, and cost-effectiveness.


Berndt R.-D.,Infokom GmbH | Takenga M.C.,Infokom GmbH | Kuehn S.,Infokom GmbH | Preik P.,Infokom GmbH | And 6 more authors.
2011 IEEE 13th International Conference on e-Health Networking, Applications and Services, HEALTHCOM 2011 | Year: 2011

Mobile telemedical applications are of crucial importance today as they do offer the potential to improve the quality of the health care related services. It has been proven that the leading cause of several illnesses and diseases are stress and the lack of fitness practices. Based on that, a system capable of estimating and monitoring both stress and fitness levels without a physical consultation of a medical specialist is presented in this work. A correlation between physiological parameters and stress or fitness is explored in the developed intelligent expert system. In order to enable the implementation of such a complex system, a flexible Telematics Platform is conceived. This Telematics Platform does guarantee a secure data communication involving encryption and a suitable visualization of the fitness and stress assessment results on both the patient's mobile phone and on a web-based portal. Moreover, the platform is scalable and can therefore be easily extended in order to support different kinds of telemedical applications. The system presented in this paper does enable the efficient and cost-effective stress and fitness monitoring of patients while being at home or practicing their daily jobs with their subsequent eventual mobility. © 2011 IEEE.


Takenga M.C.,Infokom GmbH | Berndt R.-D.,Infokom GmbH | Kuehn S.,Infokom GmbH | Preik P.,Infokom GmbH | And 7 more authors.
Telemedicine and e-Health | Year: 2012

Lack of regular physical activity and high stress levels are the leading causes of several illnesses. There is thus a real need for a personal low-cost and mobile monitoring solution over extended periods to prevent health risks. Based on the above fact, this article presents a system capable of estimating and monitoring both stress and fitness levels without a physical consultation of a medical specialist. The system consists of three main subcomponents: a mobile real-time acquisition of physiological as well as subjective data, an expert model for stress and fitness estimations based on physiological signals collected from wireless vital sensors, and a secure and scalable telematics platform on which the entire system is embedded. Features and tasks performed by the telematics platform will be presented. The experimental part of the work involved a representative number of subjects. Results for 110 subjects whose fitness levels were assessed at different periods of the year and 50 individuals whose stress scores were assessed at different times of the day showed a high correlation of the estimated values with the true ones. The application of such a low-cost monitoring system will improve the quality of service in preventive medicine. © 2012 Mary Ann Liebert, Inc.


Berndt R.-D.,Infokom GmbH | Takenga M.C.,Infokom GmbH | Kuehn S.,Infokom GmbH | Preik P.,Infokom GmbH | And 2 more authors.
Telemedicine and e-Health | Year: 2012

Objective: The increasing number of elderly and chronically ill patients is currently stressing healthcare systems. One of the solutions for reaching an economically and socially viable solution is exploiting the benefits of modern technologies. This article presents an innovative mobile teledermatology program for assisting both the therapy and the aftercare of patients suffering from skin diseases. Subjects and Methods: The system is based on store-and-forward teledermatology and consists of two main components: (1) an application implemented on the mobile phone in order to enable patients to transmit both skin image data and biofeedback information and (2) an online portal for the care providers. The key idea is to ensure a sufficient involvement of the patients in the therapy process and to motivate them through their active cooperation. Results: Smartphone applications with features as well as the online Web-based portal for medical care providers are presented. The entire system is embedded on a secure telematics platform. The system was tested at the Clinic for Skin Diseases of the University of Greifswald, Greifswald, Germany, by patients with skin diseases such as ulcus cruris, postoperative wound documentation, eczema, psoriasis, and pemphigus for a period of 1 year. Medical care providers could also analyze patients' data from the developed online Web-based application during that test period. Conclusions: Positive feedback from both medical care providers and patients confirms a high potential for mobile teledermatology as a means of dermatological healthcare delivery. © Copyright 2012, Mary Ann Liebert, Inc. 2012.


Berndt R.D.,Infokom GmbH
Telemedicine journal and e-health : the official journal of the American Telemedicine Association | Year: 2012

The increasing number of elderly and chronically ill patients is currently stressing healthcare systems. One of the solutions for reaching an economically and socially viable solution is exploiting the benefits of modern technologies. This article presents an innovative mobile teledermatology program for assisting both the therapy and the aftercare of patients suffering from skin diseases. The system is based on store-and-forward teledermatology and consists of two main components: (1) an application implemented on the mobile phone in order to enable patients to transmit both skin image data and biofeedback information and (2) an online portal for the care providers. The key idea is to ensure a sufficient involvement of the patients in the therapy process and to motivate them through their active cooperation. Smartphone applications with features as well as the online Web-based portal for medical care providers are presented. The entire system is embedded on a secure telematics platform. The system was tested at the Clinic for Skin Diseases of the University of Greifswald, Greifswald, Germany, by patients with skin diseases such as ulcus cruris, postoperative wound documentation, eczema, psoriasis, and pemphigus for a period of 1 year. Medical care providers could also analyze patients' data from the developed online Web-based application during that test period. Positive feedback from both medical care providers and patients confirms a high potential for mobile teledermatology as a means of dermatological healthcare delivery.


Takenga M.C.,Infokom GmbH
Telemedicine journal and e-health : the official journal of the American Telemedicine Association | Year: 2012

Lack of regular physical activity and high stress levels are the leading causes of several illnesses. There is thus a real need for a personal low-cost and mobile monitoring solution over extended periods to prevent health risks. Based on the above fact, this article presents a system capable of estimating and monitoring both stress and fitness levels without a physical consultation of a medical specialist. The system consists of three main subcomponents: a mobile real-time acquisition of physiological as well as subjective data, an expert model for stress and fitness estimations based on physiological signals collected from wireless vital sensors, and a secure and scalable telematics platform on which the entire system is embedded. Features and tasks performed by the telematics platform will be presented. The experimental part of the work involved a representative number of subjects. Results for 110 subjects whose fitness levels were assessed at different periods of the year and 50 individuals whose stress scores were assessed at different times of the day showed a high correlation of the estimated values with the true ones. The application of such a low-cost monitoring system will improve the quality of service in preventive medicine.


PubMed | Infokom GmbH
Type: Journal Article | Journal: Telemedicine journal and e-health : the official journal of the American Telemedicine Association | Year: 2012

Lack of regular physical activity and high stress levels are the leading causes of several illnesses. There is thus a real need for a personal low-cost and mobile monitoring solution over extended periods to prevent health risks. Based on the above fact, this article presents a system capable of estimating and monitoring both stress and fitness levels without a physical consultation of a medical specialist. The system consists of three main subcomponents: a mobile real-time acquisition of physiological as well as subjective data, an expert model for stress and fitness estimations based on physiological signals collected from wireless vital sensors, and a secure and scalable telematics platform on which the entire system is embedded. Features and tasks performed by the telematics platform will be presented. The experimental part of the work involved a representative number of subjects. Results for 110 subjects whose fitness levels were assessed at different periods of the year and 50 individuals whose stress scores were assessed at different times of the day showed a high correlation of the estimated values with the true ones. The application of such a low-cost monitoring system will improve the quality of service in preventive medicine.


PubMed | Infokom GmbH
Type: Journal Article | Journal: Telemedicine journal and e-health : the official journal of the American Telemedicine Association | Year: 2012

The increasing number of elderly and chronically ill patients is currently stressing healthcare systems. One of the solutions for reaching an economically and socially viable solution is exploiting the benefits of modern technologies. This article presents an innovative mobile teledermatology program for assisting both the therapy and the aftercare of patients suffering from skin diseases.The system is based on store-and-forward teledermatology and consists of two main components: (1) an application implemented on the mobile phone in order to enable patients to transmit both skin image data and biofeedback information and (2) an online portal for the care providers. The key idea is to ensure a sufficient involvement of the patients in the therapy process and to motivate them through their active cooperation.Smartphone applications with features as well as the online Web-based portal for medical care providers are presented. The entire system is embedded on a secure telematics platform. The system was tested at the Clinic for Skin Diseases of the University of Greifswald, Greifswald, Germany, by patients with skin diseases such as ulcus cruris, postoperative wound documentation, eczema, psoriasis, and pemphigus for a period of 1 year. Medical care providers could also analyze patients data from the developed online Web-based application during that test period.Positive feedback from both medical care providers and patients confirms a high potential for mobile teledermatology as a means of dermatological healthcare delivery.

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