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Guangzhou, China

Xu X.,South China University of Technology | Xu X.,Infinitus China Co. | Wang Z.,South China University of Technology | Zhang X.,South China University of Technology
Critical Reviews in Biotechnology

Human body harbors diverse microbes, the main components include bacteria, eukaryotes and viruses. Emerging evidences show that the human microbiota is intrinsically linked with overall health. The development of next-generation sequencing provides an unprecedented opportunity to investigate the complex microbial communities that are associated with the human body. Many factors like host genetics and environmental factors have a major impact on the composition and dynamic changes of human microbiota. The purpose of this paper is to present an overview of the relationship between human health and human microbiota (skin, nasal, throat, oral, vaginal and gut microbiota), then to focus on the factors modulating the composition of the microbiota and the future challenges to manipulate the microbiota for personalized health. © 2015 Informa Healthcare USA, Inc. Source

Huang S.-Q.,South China University of Technology | Huang S.-Q.,Infinitus China Co. | Ning Z.-X.,South China University of Technology
International Journal of Biological Macromolecules

In the present study, in order to maximize the yield of polysaccharides from Ganoderma lucidum, response surface methodology was employed to optimize the ultrasonic/microwave-assisted extraction (UMAE) conditions. The results indicated that the optimal extraction conditions were ultrasonic power of 50. W, microwave power of 284. W, extraction time of 701. s and water/solid ratio of 11.6:1, respectively. Using UMAE, the yield of polysaccharides was 115.56% above that of classical hot water extraction (HWE) and increased by 27.7% as against ultrasound-assisted extraction (UAE), which confirmed the great potential application of UMAE technology in the extraction of polysaccharides. The immunological assays results demonstrated that polysaccharides of G. lucidum extracted by ultrasonic/microwave (UMP) could improve the weight of immune organ of immunocompromised mice, restore delayed-type hypersensitivity (DTH) reaction to DFNB, improve hemolysis antibody level and natural killer cell activity at high-dose. However, UMP had no noticeable effects on phagocytosis of monocyte at the tested dosage range. © 2010. Source

Xu X.,South China University of Technology | Xu X.,Infinitus China Co. | Yan H.,South China University of Technology | Chen J.,South China University of Technology | Zhang X.,South China University of Technology
Biotechnology Advances

Mushrooms have been used as food or medicine for thousands of years. Due to low-fat content and absence of cholesterol, many mushrooms are excellent sources of protein. There are various mushroom proteins with interesting biological activities, such as lectins, fungal immunomodulatory proteins (FIP), ribosome inactivating proteins (RIP), ribonucleases, laccases, and other proteins, which have become popular sources of natural antitumor, antiviral, antimicrobial, antioxidative, and immunomodulatory agents. The aim of this review is to update the present status of bioactive proteins in mushrooms, and to discuss their biomedical potential and future prospectives. © 2011 Elsevier Inc. Source

Herbal composition having an effect of reducing uric acid, which is made from the following herbal materials in specified portions by weight: 4-30 portions of Glabrous greenbrier rhizome, 2-15 portions of Chicory, 2-15 portions of Herba

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