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Chiang H.,National Taiwan University Hospital | Liao C.-J.,Industry Technology Research Institute | Hsieh C.-H.,National Taiwan University Hospital | Shen C.-Y.,National Taiwan University Hospital | And 2 more authors.
Osteoarthritis and Cartilage | Year: 2013

Objective: Matrix-associated autologous chondrocyte implantation has been used to treat cartilage defects. We developed a biphasic cylindrical osteochondral composite construct for such use, and conducted this study to determine its feasibility for treating osteochondral lesions in human knees. Method: Ten patients with symptomatic osteochondral lesions at femoral condyles were treated by replacing pathological tissue with the construct of dl-poly-lactide-co-glycolide, whose lower body was impregnated with β-tricalcium phosphate and served as osseous phase. The construct had a chamber to load double-minced autologous cartilage, serving as source of chondrocytes. Osteochondral lesion was drill-fashioned a pit of identical dimension as the construct. Chondrocyte-laden construct was press-fit to fill the pit. Postoperative outcome was evaluated using Knee Injury and Osteoarthritis Outcome Score (KOOS) scale up to 24 months. Magnetic resonance image was taken, and sample tissue was collected with second-look arthroscopic needle biopsy at 12 months. Outcome parameters were primarily safety of surgery, and secondarily postoperative change in KOOS and regeneration of hyaline cartilage and cancellous bone. Results: No patient experienced serious adverse events. Postoperative mean KOOS in "symptoms" subscale had not changed significantly from pre-operation until 24 months; whereas those in the other four subscales were significantly higher than pre-operation at 12 and 24 months. Second-look arthroscopy showed completely filled grafted sites, with regenerate cartilaginous surfaces flushed with surrounding native joint surface. Microscopically, regenerated cartilage appeared hyaline. Conclusion: This novel construct for chondrocyte implantation is safe for surgical application in knee. It repairs osteochondral lesions of femoral condyles by successful regeneration of hyaline cartilage. © 2013 Osteoarthritis Research Society International.


Deulkar S.H.,TATA INTERACTIVE SYSTEMS | Lai W.-H.,Industry Technology Research Institute | Huang J.-L.,National University of Kaohsiung
IEEE Nanotechnology Materials and Devices Conference, IEEE NMDC 2013 | Year: 2013

Morphology of mesoporous silica has been transformed from spherical to ellipsoidal form due to the structure directing role of alpha-cyclodextrin. The product exhibits a well ordered pore structure as deciphered from the SAXRD and TEM measurements. SEM studies indicate that the samples without alpha-cyclodextrin possess a spherical form with diameters ranging from 1.5 micron to 2.5 micron. These are transformed into a cylindrical structure with aspect ratio ranging from 2.1 to 4.7. FTIR spectra reveal distinct peaks corresponding to Si-O linkage. The Brunauer-Emmett-Teller (BET) pore surface area and the pore size for the samples, range from 2.7 to 612 m2 / gm and 3.89 to 10.95 nm respectively. The formation mechanism of the elongated cylindrical mesoporous silica is proposed to occur based on the hydrophilic and hydrophobic nature existent within cyclic alpha - cyclodextrin. The stoichiometric quotient qexp captures the degree of inclusion of alpha - cyclodextrin in the Pluronic precursor. A plot of BET pore surface area vs. qexp , reveals that samples with similar qexp but with low TEOS concentration have higher BET pore surface area than those prepared with higher TEOS concentrations. This trend correlates with the hydrogen adsorption properties of the synthesized mesoporous samples, wherein samples with larger BET pore surface area, exhibit enhanced hydrogen adsorption capacity. © 2013 IEEE.


Hsu C.-M.,National Taiwan University | Lian F.-L.,National Taiwan University | Huang C.-M.,National Taipei University of Technology | Chang Y.-S.,Industry Technology Research Institute
Proceedings 2012 International Conference on System Science and Engineering, ICSSE 2012 | Year: 2012

Traffic scene understanding and perception is an important issue for intelligent vehicles and autonomous mobile robots. Especially in dynamic environments, the determination of drivable space and moving obstacles are fundamental requirement for road scene understanding. In this paper, we propose a vision-based approach combining road geometry and color features to percept road and moving obstacles in a dynamic environment from the camera mounted on the host vehicle. In the approach, a free road surface is detected first based on feature similarity search using statistical feature analysis (SFA) combined with a breadth-first search (BFS) algorithm to segment different intensity similarity regions in a road image. Then, the similarity between the road model (its color distribution) and the road region candidates is expressed by a metric derived from the Bhattacharyya distance. With the free road surface, the relative distance of preceding obstacles can easily be estimated using the obstacle scanning mechanism (OSM) and online camera calibration scheme. The experimental results have shown that the proposed approach can detect the drivable region and estimate the relative distance of preceding obstacles in real traffic scenes. © 2012 IEEE.


Tsai T.-H.,National Taiwan University | Chien H.-T.,Industry Technology Research Institute | Chen P.-H.,National Taiwan University
Nanoscale Research Letters | Year: 2011

The present study aims to investigate the effect of suspended nanoparticles in base fluids, namely nanofluids, on the thermal resistance of a disk-shaped miniature heat pipe [DMHP]. In this study, two types of nanoparticles, gold and carbon, in aqueous solution are used respectively. An experimental system was set up to measure the thermal resistance of the DMHP with both nanofluids and deionized [DI] water as the working medium. The measured results show that the thermal resistance of DMHP varies with the charge volume and the type of working medium. At the same charge volume, a significant reduction in thermal resistance of DMHP can be found if nanofluid is used instead of DI water. © 2011 Tsai et al.


Fan C.-I.,National Sun Yat - sen University | Huang V.S.-M.,Industry Technology Research Institute | Ruan H.-M.,National Taiwan University
IEEE Transactions on Computers | Year: 2014

Attribute-based encryption (ABE) is an advanced encryption technology where the privacy of receivers is protected by a set of attributes. An encryptor can ensure that only the receivers who match the restrictions on predefined attribute values associated with the ciphertext can decrypt the ciphertext. However, maintaining the correctness of all users' attributes will take huge cost because it is necessary to renew the users' private keys whenever a user joins, leaves the group, or updates the value of any of her/his attributes. Since user joining, leaving, and attribute updating may occur frequently in real situations, membership management will become a quite important issue in an ABE system. In this paper, we will present an ABE scheme which is the first ABE scheme that aims at dynamic membership management with arbitrary states, not binary states only, for every attribute. Our work also keeps high flexibility of the constraints on attributes and makes users be able to dynamically join, leave, and update their attributes. It is unnecessary for those users who do not change their attribute statuses to renew their private keys when some user updates the values of her/his attributes. Finally, we also formally prove the security of the proposed scheme without using random oracles. © 2013 IEEE.


Hsu M.,Industry Technology Research Institute | Shih A.,Industrial Technology Research Institute of Taiwan
2015 IEEE International Conference on Consumer Electronics - Taiwan, ICCE-TW 2015 | Year: 2015

In recent years, with the advances in short range communication technology, vehicles are able to communicate with each other (Vehicle-to-Vehicle, V2V) and with the Roadside (Vehicle-to-Roadside, V2R) through dedicated short range communications (DSRC) and are referred to as connected vehicles. In V2R scenario, we design and implement a Traffic Signal Control System (TSCS) for use in real-life IEEE 802.11p/1609 On-Board Units (OBUs). As this TSCS can reduce bus travel time and number of stops by employing a traffic signal priority algorithm, a reduction in bus travel times can be achieved by proper use of traffic lights. © 2015 IEEE.


Wu P.,Yuan Ze University | Hsieh J.-W.,National Taiwan Ocean University | Cheng J.-C.,Yuan Ze University | Cheng S.-C.,National Taiwan Ocean University | Tseng S.-Y.,Industry Technology Research Institute
Proceedings - International Conference on Pattern Recognition | Year: 2010

This paper presents a novel scheme to automatically and directly detect smoking events in video. In this scheme, a color-based ratio histogram analysis is introduced to extract the visual clues from appearance interactions between lighted cigarette and its human holder. The techniques of color re-projection and Gaussian Mixture Models (GMMs) enable the tasks of cigarette segmentation and tracking over the background pixels. Then, a key problem for event analysis is the non-regular form of smoking events. Thus, we propose a self-determined mechanism to analyze this suspicious event using HHM framework. Due to the uncertainties of cigarette size and color, there is no automatic system which can well analyze human smoking events directly from videos. The proposed scheme is compatible to detect the smoking events of uncertain actions with various cigarette sizes, colors, and shapes, and has capacity to extend visual analysis to human events of similar interaction relationship. Experimental results show the effectiveness and real-time performances of our scheme in smoking event analysis. © 2010 IEEE.


Li W.-T.,Industry Technology Research Institute | Wang S.-M.,Industry Technology Research Institute | Lin G.-C.,Industry Technology Research Institute
European Microwave Week 2015: "Freedom Through Microwaves", EuMW 2015 - Conference Proceedings; 2015 45th European Microwave Conference Proceedings, EuMC | Year: 2015

A fully integrated 2.45 GHz power amplifier with a power detector, harmonic suppression techniques, and temperature compensation circuits is implemented through 55-nm CMOS technology. Using bias-control variable resistors, the proposed power detector has wide dynamic range and low linear error. Utilizing the harmonic suppression techniques; the proposed power amplifier is able to deliver signals without disturbing adjacent circuits. With the temperature compensation circuit, the proposed power amplifier can provide consistent performances at different temperatures. The measured dynamic range and linear error of the power detector are 16 dB and <0.8 dB at 2.45 GHz, respectively. The power amplifier has second and third harmonic suppression of 35.6 and 43.8 dBc when the output power of the power amplifier is 17.6 dBm. These techniques are essential for high-yield mass production of power amplifier products. © 2015 EuMA.


Fan C.-I.,National Sun Yat - sen University | Huang V.S.M.,Industry Technology Research Institute | Yu Y.-C.,National Sun Yat - sen University
Mathematical and Computer Modelling | Year: 2013

Due to rapid progress in the internet and cloud computing technologies, electronic commerce is becoming more and more popular. Many people and businesses deal with their payment transactions via the Internet. The technologies of credit cards, electronic tickets, electronic cash (e-cash), and other advanced payment services have realized the vision of electronic commerce. In this paper, we proposed an off-line e-cash scheme with anonymity, unlinkability, double-spending checking, anonymity control, and fast anonymity revocation on double-spending. In an off-line e-cash scheme, the bank which could be a financial cloud server or the third party (TTP) must be able to revoke the anonymity of a user who doubly spent her/his e-cash(s). In our proposed scheme, the bank can quickly derive the identity of the user who doubly spent her/his e-cash(s) without the participation of TTP. Besides, if some illegal transactions are reported, TTP can also directly revoke the anonymity of the user who spent her/his e-cash(s) in the illegal transactions. Furthermore, we also provide traceability for the police to trace a specific user, and maybe a crime, in some situations. Finally, the security of the proposed features, unlinkability and unforgeability, are formally proved in this paper. © 2012 Elsevier Ltd.


Tang W.-X.,Industry Technology Research Institute | Tung S.-W.,Industry Technology Research Institute | Wen S.-A.,Industry Technology Research Institute | Lin K.-Y.,Industry Technology Research Institute
2013 IEEE International Conference of Electron Devices and Solid-State Circuits, EDSSC 2013 | Year: 2013

In a battery-powered device, power consumption determines the operation time and weight of the overall system. In this paper, a 10 MHz ultra-low voltage SPARK 32-bit RISC microcontroller is proposed, with low power consumption which prolongs operation time and satisfies low end applications in the meantime. The design is carried out with the TSMC 65nm LP CMOS process, and post-layout simulation indicates the SPARK microcontroller is capable of operating at 10MHz, and consuming 0.7 mW from a 0.45V supply. The overall chip layout area is 920×920 μm2. © 2013 IEEE.

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