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Chiang H.,National Taiwan University Hospital | Liao C.-J.,Industry Technology Research Institute | Hsieh C.-H.,National Taiwan University Hospital | Shen C.-Y.,National Taiwan University Hospital | And 2 more authors.
Osteoarthritis and Cartilage | Year: 2013

Objective: Matrix-associated autologous chondrocyte implantation has been used to treat cartilage defects. We developed a biphasic cylindrical osteochondral composite construct for such use, and conducted this study to determine its feasibility for treating osteochondral lesions in human knees. Method: Ten patients with symptomatic osteochondral lesions at femoral condyles were treated by replacing pathological tissue with the construct of dl-poly-lactide-co-glycolide, whose lower body was impregnated with β-tricalcium phosphate and served as osseous phase. The construct had a chamber to load double-minced autologous cartilage, serving as source of chondrocytes. Osteochondral lesion was drill-fashioned a pit of identical dimension as the construct. Chondrocyte-laden construct was press-fit to fill the pit. Postoperative outcome was evaluated using Knee Injury and Osteoarthritis Outcome Score (KOOS) scale up to 24 months. Magnetic resonance image was taken, and sample tissue was collected with second-look arthroscopic needle biopsy at 12 months. Outcome parameters were primarily safety of surgery, and secondarily postoperative change in KOOS and regeneration of hyaline cartilage and cancellous bone. Results: No patient experienced serious adverse events. Postoperative mean KOOS in "symptoms" subscale had not changed significantly from pre-operation until 24 months; whereas those in the other four subscales were significantly higher than pre-operation at 12 and 24 months. Second-look arthroscopy showed completely filled grafted sites, with regenerate cartilaginous surfaces flushed with surrounding native joint surface. Microscopically, regenerated cartilage appeared hyaline. Conclusion: This novel construct for chondrocyte implantation is safe for surgical application in knee. It repairs osteochondral lesions of femoral condyles by successful regeneration of hyaline cartilage. © 2013 Osteoarthritis Research Society International. Source


Tsai T.-H.,National Taiwan University | Chien H.-T.,Industry Technology Research Institute | Chen P.-H.,National Taiwan University
Nanoscale Research Letters | Year: 2011

The present study aims to investigate the effect of suspended nanoparticles in base fluids, namely nanofluids, on the thermal resistance of a disk-shaped miniature heat pipe [DMHP]. In this study, two types of nanoparticles, gold and carbon, in aqueous solution are used respectively. An experimental system was set up to measure the thermal resistance of the DMHP with both nanofluids and deionized [DI] water as the working medium. The measured results show that the thermal resistance of DMHP varies with the charge volume and the type of working medium. At the same charge volume, a significant reduction in thermal resistance of DMHP can be found if nanofluid is used instead of DI water. © 2011 Tsai et al. Source


Hsu M.,Industry Technology Research Institute | Shih A.,Industrial Technology Research Institute of Taiwan
2015 IEEE International Conference on Consumer Electronics - Taiwan, ICCE-TW 2015 | Year: 2015

In recent years, with the advances in short range communication technology, vehicles are able to communicate with each other (Vehicle-to-Vehicle, V2V) and with the Roadside (Vehicle-to-Roadside, V2R) through dedicated short range communications (DSRC) and are referred to as connected vehicles. In V2R scenario, we design and implement a Traffic Signal Control System (TSCS) for use in real-life IEEE 802.11p/1609 On-Board Units (OBUs). As this TSCS can reduce bus travel time and number of stops by employing a traffic signal priority algorithm, a reduction in bus travel times can be achieved by proper use of traffic lights. © 2015 IEEE. Source


Wu P.,Yuan Ze University | Hsieh J.-W.,National Taiwan Ocean University | Cheng J.-C.,Yuan Ze University | Cheng S.-C.,National Taiwan Ocean University | Tseng S.-Y.,Industry Technology Research Institute
Proceedings - International Conference on Pattern Recognition | Year: 2010

This paper presents a novel scheme to automatically and directly detect smoking events in video. In this scheme, a color-based ratio histogram analysis is introduced to extract the visual clues from appearance interactions between lighted cigarette and its human holder. The techniques of color re-projection and Gaussian Mixture Models (GMMs) enable the tasks of cigarette segmentation and tracking over the background pixels. Then, a key problem for event analysis is the non-regular form of smoking events. Thus, we propose a self-determined mechanism to analyze this suspicious event using HHM framework. Due to the uncertainties of cigarette size and color, there is no automatic system which can well analyze human smoking events directly from videos. The proposed scheme is compatible to detect the smoking events of uncertain actions with various cigarette sizes, colors, and shapes, and has capacity to extend visual analysis to human events of similar interaction relationship. Experimental results show the effectiveness and real-time performances of our scheme in smoking event analysis. © 2010 IEEE. Source


Hsu C.-M.,National Taiwan University | Lian F.-L.,National Taiwan University | Huang C.-M.,National Taipei University of Technology | Chang Y.-S.,Industry Technology Research Institute
Proceedings 2012 International Conference on System Science and Engineering, ICSSE 2012 | Year: 2012

Traffic scene understanding and perception is an important issue for intelligent vehicles and autonomous mobile robots. Especially in dynamic environments, the determination of drivable space and moving obstacles are fundamental requirement for road scene understanding. In this paper, we propose a vision-based approach combining road geometry and color features to percept road and moving obstacles in a dynamic environment from the camera mounted on the host vehicle. In the approach, a free road surface is detected first based on feature similarity search using statistical feature analysis (SFA) combined with a breadth-first search (BFS) algorithm to segment different intensity similarity regions in a road image. Then, the similarity between the road model (its color distribution) and the road region candidates is expressed by a metric derived from the Bhattacharyya distance. With the free road surface, the relative distance of preceding obstacles can easily be estimated using the obstacle scanning mechanism (OSM) and online camera calibration scheme. The experimental results have shown that the proposed approach can detect the drivable region and estimate the relative distance of preceding obstacles in real traffic scenes. © 2012 IEEE. Source

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