Industrial Research Laboratories Complex

Karachi, Pakistan

Industrial Research Laboratories Complex

Karachi, Pakistan
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Jalbani N.,Industrial Research Laboratories Complex | Aftab A.K.,University of Sindh | Bhutto S.,Industrial Research Laboratories Complex | Ahmed F.,Industrial Research Laboratories Complex | Mahroze A.K.,Industrial Research Laboratories Complex
International Food Research Journal | Year: 2014

The aim of this study was to determine the level of toxic elements in rice samples. Microwave-assisted digestion method was used for sample preparation to determine the cadmium (Cd) and lead (Pb). A Plackett-Burman experimental design (PBD) was used as a multivariate strategy for the evaluation of the effects of some important variables at once. Furthermore, certain variable showed up as significant, and they were optimized by using Plackett-Burman, whereas most significant variables were optimized by 23+ star central composite designs (CCD). The accuracy of the optimized procedure ensured by the analysis of certified reference material (CRM). Outcomes are that the highest values of Cd found in brown rice (0.0889 ± 0.0056 mg/Kg), whilst the lowest concentration was found in white rice samples 0.001 ± 0.0001 mg/Kg. There is a relatively significant differences were found between the two categories of rice samples at the p-values (P = 0.05) © All Rights Reserved.

Lateef A.,University of Punjab | Nazir R.,Applied Scientific Research | Jamil N.,University of Punjab | Alam S.,Industrial Research Laboratories Complex | And 3 more authors.
Microporous and Mesoporous Materials | Year: 2016

The research deals with assessing the feasibility of using nano-zeolite as support material for the provision of nine out of thirteen primary, secondary and micro-nutrients on slow release basis. The nano-zeolite (NZ) and nano-composite (ZNC), synthesized using simple chemical approach, were characterized by different techniques including FT-IR, powder XRD, SEM/EDX, AFM and TGA/DSC. Physical characterization was also performed by using standard methods. The lab studies showed that there is considerable increase in water retention capacity, water absorbency, equilibrium water content and swelling ratio of ZNC as compared to the NZ which is favorable for maintaining water level in the soil. The nano-composite prepared is safe to use as compared to conventional fertilizers as indicated by salt index value. Nutrients slow release studies carried out in water and soil confirmed the long term availability of all the doped nutrients to the plant over the full crop cultivation period that is suitable for promoting germination, growth, flowering and fruiting. Hence, the results obtained showed that the prepared nano-composite materials can be safely used as environment friendly fertilizer. © 2016 Published by Elsevier Inc.

Kandhro A.A.,Industrial Research Laboratories Complex | Saleem R.,Industrial Research Laboratories Complex | Laghari A.H.,Industrial Research Laboratories Complex | Sultana R.,Industrial Research Laboratories Complex | And 2 more authors.
Journal of the Chemical Society of Pakistan | Year: 2014

The present study depicts spectroscopic method development to deliver a rapid, simple and reproducible quantification of pure refined olive oil (PROO) adulterant in extra virgin olive oil (EVOO) using partial least square (PLS) regression (statistical parameter). Single bounce attenuated total reflectance (SB-ATR) Fourier transform infrared (FTIR) was choice in the developed method. Blended standards of PROO and EVOO were obtained by their weight by weight percentage and the values were used to construct calibration curves for quantification. The optimum regression values (i.e. >0.99) were achieved using the combined frequencies of 3105-2761, 1838-1687, and 1482-440 cm-1 with regression coefficients (R2) 0.99718 and achieved residual mean square error of calibration (RMSEC) 1.40% w/w. To determine the suitability of developed method principal component spectra (PCS) diagnostic was also used. The results of the present study prove that the developed methods reported in preceding studies can be good option for more rapid and accurate determination of PROO adulteration in EVOO.

Ngankeu Pagning A.L.,University of Dschang | Ngankeu Pagning A.L.,University of Karachi | Tamokou J.-D.-D.,University of Dschang | Lateef M.,Industrial Research Laboratories Complex | And 4 more authors.
Phytochemistry Letters | Year: 2016

The CH2Cl2-MeOH (1:1) extract of the whole plant of Rhynchospora corymbosa (L.) Britton, led to the isolation of two new secondary metabolites 1, 2 (1 and 2a) together with nine known compounds 3-11. The flavone named tricin (11) was partially modified by esterification reaction to three semi-synthetic derivatives 11a-11c). Their structures were elucidated on the basis of spectroscopic analysis. The antimicrobial, tyrosinase and butyrylcholinesterase inhibitory activities revealed that, extract and compounds 1, 2a, 6, 11, 11a-c exhibited variable MICs (1-512 μg/mL) and significant antimicrobial activity, depending on the microbial species; Antifungal activity of 11 and 11c was more important than that of nystatine used as reference antifungal drugs. The inhibitory activity of 4 (IC50 = 43.28 μg/mL) was higher than that of the kojic acid (IC50 = 49.62 μg/mL) which is known tyrosinase inhibitor. The extract, compounds 1, 7-10, and 11a-c exhibited significant (p < 0.05) differences in the concentrations of 50% BuChE inhibition (IC50). These results suggest that the, R. corymbosa could be exploited as a potential source of natural antimicrobial, and antibutyrylcholinesterase agents as well as tyrosinase inhibitors. © 2016 Elsevier Ltd. All rights reserved.

Aslam M.,Industrial Research Laboratories Complex | Aslam M.,University of Karachi | Anis I.,University of Karachi | Afza N.,Industrial Research Laboratories Complex | And 7 more authors.
Journal of the Chilean Chemical Society | Year: 2013

Schiff bases, 2-{[(2-hydroxyphenyl)methylidene]amino}phenol (4) and 2-{[3-4-(dimethylamino)phenyl-2-propenylidene]amino}phenol (5), have been synthesized by the condensation of 2-aminophenol (1) with 2-hydroxybenzaldehyde (2) and 4-dimethylaminocinnamaldehyde (3), respectively. They showed good lipoxygenase inhibition and antioxidant activities, as compound 4 showed potent antioxidant activity. The products also showed good activities against Gram-positive: S. intermedius, B. subtilis and S. aureus, and Gram-negative: E. coli and S. typhi bacteria, as compounds 5 and 4 are excellent active against B. subtilis and S. typhi, respectively. These good to potent activities may be due to the presence of free hydroxyl and amino groups. They showed non-significant urease inhibition activity.

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