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Dubey P.,Indira Gandhi Institute of Medical science
Annals of Cardiac Anaesthesia | Year: 2014

A 3-month-old male child underwent uneventful inguinal herniotomy under general anesthesia. After extubation, airway obstruction followed by pulmonary edema appeared for which the baby was reintubated and ventilated. The baby made a complete recovery and extubated after about 2 h. A post-operative computed tomography scan revealed a posterior mediastinal cystic mass abutting the tracheal bifurcation. Presumably, extrinsic compression by the mass on the tracheal bifurcation led to the development of negative pressure pulmonary edema. Source


Haque S.S.,Indira Gandhi Institute of Medical science
Bratislava Medical Journal | Year: 2012

Objectives: Typhoid fever is a global health problem caused by Salmonella. Salmonellae are gramnegative, flagellate, nonsporulating, facultative anaerobic bacilli that ferment glucose, reduce nitrate to nitrite, and synthesize peritrichous flagella when motile. Nowadays, most of the drugs are resistant, the fact of which compels the search for formulated drugs. Nitric oxide (NO) and its congeners react with different compounds or radicals probably mediating the broad-spectrum antimicrobial activity of reactive nitrogen species (RNS) as well as reactive oxygen species (ROS) against diverse microorganisms. Exogenous administration of L-arginine results in increased NO production. The formulation of NO precursors, (i.e. of L -arginine and ciprofloxacin) is used against experimentally induced salmonellosis. Lipid hydroperoxide can be decomposed to produce alkoxy and peroxy radicals which eventually yield numerous carbonyl products such as malondialdehyde (MDA). Material and methods: Estimation of lipid peroxidation (LPO) was done by modified method of Utley et al (1967). Results and discussion: Infection with S. typhimurium significantly induced lipid peroxidation on days 8 and 11 as indicated by enhancement of MDA levels compared to the control mice. Source


Haque S.S.,Indira Gandhi Institute of Medical science
Macedonian Journal of Medical Sciences | Year: 2014

AIM: The aim was to examine the induction of DTH reaction in the animals treated with L-Arginine, ciprofloxacin and their combination followed by immunization with S. typhimurium cell lysate as assessed by the footpad swelling test.RESULTS: The results of the present study showed that the induction of DTH reaction in the animals treated with L-Arginine, ciprofloxacin and their combination followed by immunization with S. typhimurium cell lysate using an antigen revealed that the treatment with combination increased foot pad swelling significantly as compared to saline treated control animals at 48 hour which was followed by a decrease of the swelling at 72 hour.CONCLUSIONS: Animal treated with L-arginine, ciprofloxacin and their combination showed increased cell mediated immune responses as evident by DTH response whereas groups (B+S) shows decreases CMI responses.OBJECTIVES: Typhoid fever an important causes of illness and death, particularly among children and adolescents in south-central and Southeast Asia, where enteric fever is associated with poor sanitation and unsafe food and water. Cell-mediated immunity (CMI) plays an important role for the survival of the host in experimental salmonellosis. Nitric oxide (NO) is the one of the product of macrophages activated by cytokines, microbial compounds or both, is derived from the amino acid L-arginine by the enzymatic activity of inducible nitric oxide synthase (iNOS or NOS2) which acts as antimicrobial molecule. © 2014 Haque. Source


Khandelwal A.K.,Indira Gandhi Institute of Medical science
UroToday International Journal | Year: 2013

Crossed renal ectopia is a rare congenital malformation and is the second most common fusion anomaly after a horseshoe kidney. Crossed ectopic kidneys are fused to their ipsilateral mate in 90% of cases. crossed fused renal ectopia is usually diagnosed when other disease states are being investigated. It rarely causes significant clinical problems. Treatment is only indicated for the complication of the anomaly rather than for the anomaly itself. © 2013 Digital Science Press, Inc. Source


Khandelwal A.K.,Indira Gandhi Institute of Medical science
UroToday International Journal | Year: 2013

A urinoma is a continued perinephric or peripelvic extravasation of urine leading to the formation of encapsulated retroperitoneal urine collection due to the disruption of the urinary collecting system. Non-obstetric urinomas are usually the result of trauma, a urologic procedure, infection, and nephrolithiasis. We report a case of perirenal urinomas that were detected during the postpartum period. © 2013 Digital Science Press, Inc. Source

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