Indiana University is a multi-campus public university system in the state of Indiana, United States. Indiana University has a combined student body of more than 110,000 students, including approximately 43,000 students enrolled at the Indiana University Bloomington campus and approximately 31,000 students enrolled at the Indiana University – Purdue University Indianapolis campus. Wikipedia.
Bolder Biotechnology, Inc., Indiana University and Medical College of Wisconsin | Date: 2016-09-19
Methods and compositions comprising hematopoietic growth factor proteins and/or protein analogs thereof and/or combinations thereof and angiotensin converting enzyme inhibitors to treat the acute and long term adverse effects of radiation exposure in subjects who have been or will be exposed to radiation are disclosed.
Indiana University | Date: 2016-08-05
Methods for modulating inflammation using progesterone metabolites are disclosed. More particularly, methods of administering progesterone metabolites, 6-hydroxyprogesterone (6-OHP) and 16-hydroxyprogesterone (16-OHP) are disclosed for mitigating inflammation in various tissue types in the body.
Indiana University | Date: 2016-10-05
Methods of diagnosing excessive alcohol use are disclosed herein. More particularly, the present disclosure is directed to methods of diagnosing excessive alcohol use by identifying expression levels of various serum biomarkers. In some embodiments, expression levels of these biomarkers are affected by alcohol use even up to 30 days after consumption of alcohol.
Indiana University | Date: 2016-10-28
Methods comprising electronically receiving information of a reflection of a known first sound pulse, electronically receiving information of a reflection of a known second sound pulse, determining, by a processor, a change in a first property between a known first sound pulse and a reflection of the known first sound pulse, determining, by the processor, a change in a second property between a known second sound pulse and a reflection of the known second sound pulse, comparing, by the processor, the change in the first property of the first known sound pulse with the change in the second property of the second known sound pulse, and determining, by the processor, a condition of a well in response to the comparison of the change of the first property with the change of the second property are disclosed. Systems for determining a condition of a well are also disclosed.
Indiana University and Assembly Biosciences Inc. | Date: 2017-03-15
Described herein are methods for identifying compounds useful for the treatment of infection by hepatitis B virus (HBV) and for identifying compounds useful for the same.
Indiana University | Date: 2017-04-19
A method and apparatus for extracting tissue samples are disclosed herein. An example apparatus disclosed herein includes a first sidewall and a second sidewall spaced apart from the first sidewall. The example apparatus also includes a track to receive a blade between the first sidewall and the second sidewall. The track is to guide the blade to penetrate skin of a patient to a predetermined depth of invasion.
Indiana University | Date: 2016-08-19
Methods of manufacturing comprising placing a mixture comprising sulfur powder, a carbon nanotube, an alcohol soluble binder, and a solvent into a cast and removing a solvent from the mixture to form an electrode are disclosed. Electrodes and batteries comprising sulfur, a carbon nanotube, and an alcohol soluble binder are also disclosed.
Indiana University | Date: 2017-01-18
The present disclosure relates generally to methods and compositions useful in cell and tissue biology and therapeutics. In particular, an in vitro method for differentiating pluripotent cells into endothelial colony forming cell-like cells (ECFC-like cells) is provided. A purified human cell population of NRP-1+CD31+ ECFC-like cells is provided, wherein at least some of the cells in the population have a high proliferation potential. Therapeutic and test agent screening methods for using the cell populations of the present disclosure are provided.
Indiana University and Assembly Biosciences Inc. | Date: 2017-01-18
ABSTRACT The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
Kaplan M.H.,Indiana University
Immunological Reviews | Year: 2013
CD4+ T-helper cells regulate immunity and inflammation through the acquisition of potential to secrete specific cytokines. The acquisition of cytokine-secreting potential, in a process termed T-helper cell differentiation, is a response to multiple environmental signals including the cytokine milieu. The most recently defined subset of T-helper cells are termed Th9 and are identified by the potent production of interleukin-9 (IL-9). Given the pleiotropic functions of IL-9, Th9 cells might be involved in pathogen immunity and immune-mediated disease. In this review, I focus on recent developments in understanding the signals that promote Th9 differentiation, the transcription factors that regulate IL-9 expression, and finally the potential roles for Th9 cells in immunity in vivo. © 2013 John Wiley & Sons A/S.