Bangalore, India
Bangalore, India

Indian Institute of Science is a public university for scientific research and higher education located in Bengaluru , India. Established in 1899 with active support from Jamshetji Tata it is also locally known as the "Tata Institute". It acquired the status of a Deemed University in 1958. IISc is widely regarded as India's finest institution in its field, and has made significant contribution to advanced computing, space, and nuclear technologies. Wikipedia.


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The present disclosure relates to aluminum based alloys and a method for producing the aluminium based alloys. The method comprises acts of, casting of the aluminium based alloy in a chilled casting mould. Then, aging the cast aluminium based alloy at a first predetermined temperature for a first predetermined time. The aging results in the formation of a first precipitate. Followed by this, solutionizing the aluminium based alloy at a second predetermined temperature for a second predetermined time such that the major alloying element is dissolved in aluminium matrix without much affecting the first precipitate. Then, aging the aluminium based alloy at a third predetermined temperature for a third predetermined time. The aging results in the formation of a second precipitate.


The invention discloses a method for the synthesis of monodispersed luminescent quantum dots of transition metal dichalcogenides (TMDC), single- or few-layered, using a single-step electrochemical exfoliation that involves dilute ionic liquid and water. The method disclosed helps to obtain nanoclusters of TMDC of desired size including small sizes ranging up to 6 nm, by varying the concentration of the electrolyte and the applied DC voltage. The invention further discloses a method by which mono- or few-layered luminescent transition metal dichalcogenides can be directly deposited onto conducting substrates in a uniform manner. The monodispersed single- or few-layered luminescent TMDC and electro-deposited substrates exhibit improved electronic conductivity and new active sites, making them suitable as high-performance electrocatalysts in hydrogen evolution reactions in solar water-splitting applications and also as electrodes for solar cell applications.


Patent
Indian Institute of Science | Date: 2015-03-21

Embodiments herein present the invention of a class of Tungsten (W) free Cobalt based (-) superalloys with the basic chemical composition comprising in % by weight: 0.5 to 10 Aluminium (Al) and 1 to 15 Molybdenum (Mo) with at least one or both of 0.5 to 12 Niobium (Nb) and 0.5 to 12 Tantalum (Ta), with the remainder being Cobalt (Co). Some part of the cobalt can be replaced by nickel (50% or less). In Nickel added alloys, some part of either cobalt of nickel can be replaced by at least one among the transition metal selected from the group consisting of 10% or less Iridium, 10% or less Platinum, 10% or less Palladium, 15% or less Chromium and combination thereof. Again in nickel added alloys, further addition of at least one among the transition metals zirconium (5% or less), hafnium (5% or less), vanadium (5% or less), titanium (5% or less), and yttrium (5% or less), boron (2% or less), carbon (2% or less), rhenium (10% or less), ruthenium (5% or less) for further fine tune the solvus temperature, volume fraction of and creep properties.


Patent
Indian Institute of Science | Date: 2017-01-25

The present invention relates to compounds that inhibit the activity of Type III deiodinase (DIO3). The present invention further relates to methods for treating or preventing depression, depression associated with other psychiatric or general medical diseases or conditions, condition amenable to treatment with known anti-depressants and cancer, particularly by using the compounds of the invention.


Patent
Indian Institute of Science | Date: 2017-03-08

The present disclosure relates to a polypeptide comprising hemagglutinin stem domain fragments that can elicit broadly cross-reactive anti-influenza antibodies and confer protection against influenza virus. The disclosure also provides a method of preparing the polypeptide with biochemical and biophysical properties that enhance its immunogenic properties. Also provided are recombinant DNA constructs, vectors, and host cells comprising the nucleic acid encoding the polypeptide, as well as uses of the polypeptide, particularly in the prevention, and detection of influenza.


The invention is for an increased isoprenoid production by carotenoid optimization in an expression system and the carotegenic gene for optimization may be geranylgeranyl diphosphate synthase (GGPPS), phytoene synthase (PSY1), conserved CRTI or mutated CRT1_(A393T), BT1 of S. cerevisae. The carotogenic gene from red yeast which includes Rhodosporidium spp. Rhodotorula spp, Sporidiobolus spp., Leucosporidium spp., Sporobolomyes spp. is selected.


Desiraju G.R.,Indian Institute of Science
Angewandte Chemie - International Edition | Year: 2011

Speak not against my bond: Another definition of the hydrogen bond? Strong hydrogen bonds satisfy all current definitions of this phenomenon, but as weaker interactions X-H⋯Y-Z have been brought into the scope of hydrogen bonding, the definitions have had to change. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Ramaswamy S.,Indian Institute of Science
Annual Review of Condensed Matter Physics | Year: 2010

Active particles contain internal degrees of freedom with the ability to take in and dissipate energy and, in the process, execute systematic movement. Examples include all living organisms and their motile constituents such as molecular motors. This article reviews recent progress in applying the principles of nonequilibrium statistical mechanics and hydrodynamics to form a systematic theory of the behavior of collections of active particles - active matter - with only minimal regard to microscopic details. A unified view of the many kinds of active matter is presented, encompassing not only living systems but inanimate analogs. Theory and experiment are discussed side by side. Copyright © 2010 by Annual Reviews. All rights reserved.


Ray S.,Indian Institute of Science
Current Opinion in Neurobiology | Year: 2015

Brain signals often show fluctuations in particular frequency bands, which are highly conserved across species and are associated with specific behavioural states. Such rhythmic patterns can be captured in the local field potential (LFP), which is obtained by low-pass filtering the extracellular signal recorded from microelectrodes. However, LFP also captures other neural processes that are associated with spikes, such as synaptic events preceding a spike, low-frequency component of the action potential ("spike bleed-through") and spike afterhyperpolarization, which pose difficulties in the estimation of the amplitude and phase of the rhythm with respect to spikes. Here we discuss these issues and different techniques that have been used to dissociate the rhythm from other neural events in the LFP. © 2014.


Desiraju G.R.,Indian Institute of Science
Journal of the American Chemical Society | Year: 2013

How do molecules aggregate in solution, and how do these aggregates consolidate themselves in crystals? What is the relationship between the structure of a molecule and the structure of the crystal it forms? Why do some molecules adopt more than one crystal structure? Why do some crystal structures contain solvent? How does one design a crystal structure with a specified topology of molecules, or a specified coordination of molecules and/or ions, or with a specified property? What are the relationships between crystal structures and properties for molecular crystals? These are some of the questions that are being addressed today by the crystal engineering community, a group that draws from the larger communities of organic, inorganic, and physical chemists, crystallographers, and solid state scientists. This Perspective provides a brief historical introduction to crystal engineering itself and an assessment of the importance and utility of the supramolecular synthon, which is one of the most important concepts in the practical use and implementation of crystal design. It also provides a look to the future from the viewpoint of the author, and indicates some directions in which this field might be moving. © 2013 American Chemical Society.

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