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Chennai, India

The 'Indian Institute of Information Technology Design and Manufacturing Jabalpur' is an Indian Institute of Information Technology and a deemed university in Jabalpur that focuses on Information Technology enabled Design and Manufacturing. It was declared to be Institute of National Importance by Government of India under IT Act. Wikipedia.

Godson L.,AIR INDIA | Raja B.,Indian Institute of Information Technology, Design and Manufacturing | Mohan Lal D.,AIR INDIA | Wongwises S.,King Mongkuts University of Technology Thonburi
Renewable and Sustainable Energy Reviews | Year: 2010

A colloidal mixture of nano-sized particles in a base fluid, called nanofluids, tremendously enhances the heat transfer characteristics of the original fluid, and is ideally suited for practical applications due to its marvelous characteristics. This article addresses the unique features of nanofluids, such as enhancement of heat transfer, improvement in thermal conductivity, increase in surface volume ratio, Brownian motion, thermophoresis, etc. In addition, the article summarizes the recent research in experimental and theoretical studies on forced and free convective heat transfer in nanofluids, their thermo-physical properties and their applications, and identifies the challenges and opportunities for future research. © 2009 Elsevier Ltd. All rights reserved.

Jena N.R.,Indian Institute of Information Technology, Design and Manufacturing
Journal of Biosciences | Year: 2012

DNA is continuously attacked by reactive species that can affect its structure and function severely. Structural modifications to DNA mainly arise from modifications in its bases that primarily occur due to their exposure to different reactive species. Apart from this, DNA strand break, inter- and intra-strand crosslinks and DNA-protein crosslinks can also affect the structure of DNA significantly. These structural modifications are involved in mutation, cancer and many other diseases. As it has the least oxidation potential among all the DNA bases, guanine is frequently attacked by reactive species, producing a plethora of lethal lesions. Fortunately, living cells are evolved with intelligent enzymes that continuously protect DNA from such damages. This review provides an overview of different guanine lesions formed due to reactions of guanine with different reactive species. Involvement of these lesions in inter- and intra-strand crosslinks, DNA-protein crosslinks and mutagenesis are discussed. How certain enzymes recognize and repair different guanine lesions in DNA are also presented. © Indian Academy of Sciences.

Amarnath M.,Indian Institute of Information Technology, Design and Manufacturing | Krishna I.R.P.,Indian Institute of Technology Madras
Tribology International | Year: 2013

Gears are used for transmission of power, motion or both. Under increased power and higher speeds, tribological failures such as scuffing, pitting, mild wear and tooth breakage are of major concern. This paper presents the results of experimental investigations carried out to assess wear in spur gears of a back-to-back gear box under accelerated test conditions. The studies considered the estimation of specific lubricant film thickness and its effects on the fault growth on gear teeth surface. Ensemble empirical mode decomposition (EEMD) technique is used to extract the fault related features from the vibration signals acquired from the gearbox. The results highlight the advantage of EEMD technique for effective assessment of wear in spurgears. © 2013 Elsevier Ltd.

Amarnath M.,Indian Institute of Information Technology, Design and Manufacturing | Praveen Krishna I.R.,Indian Institute of Space Science and Technology
Measurement: Journal of the International Measurement Confederation | Year: 2014

Gear is a vital transmission element, finding numerous applications in small, medium and large machinery. Excessive loads, speeds and improper operating conditions may cause defects on their bearing surfaces, thereby triggering abnormal vibrations in whole machine structures. This paper describes the implementation of empirical mode decomposition (EMD) method for monitoring simulated faults using vibration and acoustic signals in a two stage helical gearbox. By using EMD method, a complicated signal can be decomposed into a number of intrinsic mode functions (IMF) based on the local characteristic time scale of the signal. Vibration and acoustic signals are decomposed to extract higher order statistical parameters. Results demonstrate the effectiveness of EMD based statistical parameters to diagnose severity of local faults on helical gear tooth. Kurtosis values from EMD and that obtained from vibration and acoustic signals are compared to demonstrate the superiority of EMD based technique. © 2014 Elsevier Ltd. All rights reserved.

Jena N.R.,Indian Institute of Information Technology, Design and Manufacturing | Mishra P.C.,Banaras Hindu University
Free Radical Biology and Medicine | Year: 2012

DNA damage by endogenous and exogenous agents is a serious concern, as the damaged products can affect genome integrity severely. Damage to DNA may arise from various factors such as DNA base modifications, strand break, inter- and intrastrand crosslinks, and DNA-protein crosslinks. Among these factors, DNA base modification is a common and important form of DNA damage that has been implicated in mutagenesis, carcinogenesis, and many other pathological conditions. Among the four DNA bases, guanine (G) has the smallest oxidation potential, because of which it is frequently modified by reactive species, giving rise to a plethora of lethal lesions. Similarly, 8-oxo-7,8-dihydroguanine (8-oxoG), an oxidatively damaged guanine lesion, also undergoes various degradation reactions giving rise to several mutagenic species. The various products formed from reactions of G or 8-oxoG with different reactive species are mainly 2,6-diamino-4-oxo-5-formamidopyrimidine, 2,5-diamino-4H-imidazolone, 2,2,4-triamino-5-(2H)-oxazolone, 5-guanidino-4-nitroimidazole, guanidinohydantoin, spiroiminodihydantoin, cyanuric acid, parabanic acid, oxaluric acid, and urea, among others. These products are formed from either ring opening or ring opening and subsequent rearrangement. The main aim of this review is to provide a comprehensive overview of various possible reactions and the mechanisms involved, after which these ring-opened and rearranged products of guanine would be formed in DNA. The biological significance of oxidatively damaged products of G is also discussed. © 2012 Elsevier Inc.

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