Milano, Italy
Milano, Italy

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The present invention relates to compositions containing, as their only active ingredients, an extract of Curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and an extract selected from Echinacea spp extract or lipophilic extract of Zanthoxylum spp, which are useful in the topical and systemic treatment of peripheral pain and of superficial and deep inflammatory and painful conditions. The compositions according to the invention are particularly effective in the treatment of osteoarthritis and rheumatoid arthritis in patients unable to tolerate long-term treatment with NSAIDs or steroids.


Process for removing pesticides from Ginkgo biloba extracts, which involves submitting an extract obtained by conventional methods to the following steps:


The present invention relates to combinations of an agent that stimulates cell proliferation and an anti-inflammatory/analgesic, which are useful in the treatment of peripheral ulcers of various origins, such as radiation dermatitis, diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores, and the associated skin infections, proctitis, vulvovaginitis and haemorrhoids with vascular lesions. These combinations can be presented as formulations for topical use.


Disclosed are compositions containing an extract of Curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and a lipophilic extract of Zingiber officifiale, for use in the treatment of osteoarthritis.


Patent
INDENA S.p.A. | Date: 2016-12-14

The invention relates to a solid dispersion comprising Coenzyme Q_(10) and a phospholipid, in the presence of a cellulosic derivative and/or a polymeric material belonging to the groups of oligo and polysaccharides, linear and/or cross-linked polymers of N-vinyl-2-pyrrolidone, linear polymers of vinyl alcohol, polymers of vinyl acetate, co-polymers of methacrylic acid and ethyl acrylate, co-polymers of ethylene oxide and propylene oxide, polyethylene glycols.


The present invention relates to the use of glucomoringin (GMG) and of the corresponding isothiocyanate derivative glucomoringin des-thioglucoside (GMG-ITC) as modulators of peripheral pain with specific reference to that linked with diabetic peripheral neuropathy and chemotherapy-induced neuropathy.


Patent
Indena S.P.A. | Date: 2015-03-26

The present invention refers to an amorphous form of a thiocolchicine derivative, IDN 5404, to a process for producing it and to pharmaceutical compositions thereof. The amorphous form is characterised by the XRPD pattern, DSC profile and/or TG/DTA profile.


Disclosed is a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia for the treatment of itching, peripheral pain, superficial and deep inflammatory and painful states, pain associated with muscle spasms, herpes pain, and radiodermatitis caused by oncological radiotherapy, with or without fungal or bacterial infections.


Patent
INDENA S.p.A. and University of Antwerp | Date: 2016-09-21

The present invention relates to Gloriosa superba colchicine-poor extracts, useful in the treatment of cancers, in particular of pancreatic cancer.


Patent
Indena S.P.A. | Date: 2015-10-26

The present invention relates to a new method for isolating ingenol (C_(20)H_(28)O_(5)) from mixtures of diterpenoid esters and ingenol esters in a single step. Ingenol isolated by means of this method can be used as a precursor for the synthesis of biologically active ingenol derivatives, such as ingenol-3-angelate and ingenol-3-tigliate.

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