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Kalinga, India

Spontaneous glottis closure during expiration in infants is a normal protective refl ex that helps prevent alveolar and small airway collapse (due to compliant chest wall) and thereby maintains functional residual capacity. Endotracheal intubation eliminates this protective mechanism and puts the infant into the risk of hypoxaemia and hypercarbia. This report sums up the early detection of airway closure in a series of three intubated small infants undergoing surgery with general anaesthesia, by the appearance of typical pigtail shaped capnogram, associated with decreased end tidal carbon dioxide and mild hypoxaemia, which was successfully managed by early institution of positive end expiratory pressure. Source

Thakkar P.,Government Medical College and Hospital | Arora K.,Dayanand Medical College and Hospital | Goyal K.,Government Medical College and Hospital | Goyal K.,Dayanand Medical College and Hospital | And 4 more authors.
Journal of Perinatology

Objective:The objective of this study was to evaluate and compare the efficacy of combined sucrose and non-nutritive sucking (NNS) for analgesia in newborn infants undergoing heel-stick procedures.Study Design:This randomized control trial was conducted in the neonatal intensive care unit of a tertiary care hospital over a period of 1 year. One hundred and eighty full-term neonates with birth weight >2200 g and age >24 h were randomized to one of four interventions administered 2 min before the procedure: 2 ml of 30% sucrose (group I, n=45) or NNS (group II, n=45) or both (group III, n=45) or none (group IV, n=45). Primary outcome was composite score based on Premature Infant Pain Profile (PIPP) score.Result:Baseline variables were comparable among the groups. Median (interquartile range) PIPP score was 3 (2 to 4) in group III as compared with 7 (6.5 to 8) in group I, 9 (7 to 11) in group II and 13 (10.5 to 15) in group IV. Group III had significant decrease in the median PIPP score compared with other groups (P=0.000). Median PIPP score also decreased significantly with any intervention as compared with no intervention (P=0.000).Conclusion:Sucrose and/or NNS are effective in providing analgesia in full-term neonates undergoing heel-stick procedures, with the combined intervention being more effective compared with any single intervention. © 2016 Nature America, Inc. Source

Kar B.R.,IMS and SUM Hospital
Indian Journal of Dermatology

Nevus depigmentosus is a congenital hypomelanotic condition for which no effective treatments are available. The hypopigmentation is permanent and enlarges in proportion with growth in the person. Here, I report a patient of nevus depigmentosus on whom we performed suction blister grafting and the resultant pigmentation was satisfactory even at a follow-up after 10 years. Source

Tripathy P.,IMS and SUM Hospital
Neurologia i neurochirurgia polska

Primary intradural extramedullary ependymomas are very rare. They are called primary in this location as they do not have any connection with the central nervous system. They usually develop from an ectopic ependymal cell nest. To the best of our knowledge, only 10 cases have been described in the literature. We report two cases of large sausage-shaped intradural extramedullary ependymoma in the lumbosacral area. Source

Mohapatra D.,IMS and SUM Hospital | Behera M.,IMS and SUM Hospital
International Journal of Pharma and Bio Sciences

Pregnancy induced hypertension is one of the most common and challenging medical complication of pregnancy as this complex disease continues to defeat all efforts to bring about satisfactory and rewarding policy of management because of its poor understanding of pathological basics. It is the hypertension that results from direct gravid state and is one of the critical obstetric complications attributing to high incidence of fetal and maternal morbidity and mortality. This complication of pregnancy though responsible for large number of maternal and perinatal deaths, can be easily prevented and controlled by early detection of disease and proper management. In this study, we assessed the extent to which liver function tests can be used to predict the adverse maternal outcomes. Source

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