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Sordo L.,Institute Salud Carlos III | Sordo L.,CIBER ISCIII | Chahua M.,Institute Salud Carlos III | Bravo M.J.,Institute Salud Carlos III | And 11 more authors.
Addictive Behaviors | Year: 2012

The aim of this study was to determine the prevalence of recent (last 12. months) depression in regular young heroin users and to ascertain factors associated with depression in this population, broken down by gender. A sample of 561 participants completed a cross-sectional survey. Eligibility criteria were: age 30. years or younger, and having used heroin for at least 12. days in the last 12. months and at least one day in the last 3. months. Participants were recruited outside of health-care facilities in the cities of Barcelona, Madrid and Seville by targeted sampling and chain referral methods. Depression was assessed using the World Mental Health Composite International Diagnostic Interview. The prevalence of recent depression was 22.3% (35.2% among women and 17.3% among men, p < 0.001). In the multivariate analysis, the factors positively associated with recent depression in the whole sample were female gender, age 25 or less, inability to work due to health problems and high risk consumption of alcohol. Among woman, the related variables were age 25 or less, cocaine dependence in the last 12. months, and alcohol consumption in that period. Among men, employment status was the only related variable. Analysis of an overall sample without the gender breakdown may hide important differences in the factors associated with depression in men and women. Both prevention and treatment of depression should rely on specific gender analysis. © 2011 Elsevier Ltd. Source

Guitart A.M.,Agencia de Salut Publica de Barcelona | Guitart A.M.,Biomedical Research Institute Sant Pau | Espelt A.,Agencia de Salut Publica de Barcelona | Espelt A.,Biomedical Research Institute Sant Pau | And 14 more authors.
Gaceta Sanitaria | Year: 2011

Objectives: To estimate excess mortality in patients with an alcohol use disorder and to calculate the population-based impact attributable to this disorder, with emphasis on differences according to gender and age. Methods: We carried out a longitudinal study of a dynamic retrospective cohort in which 7,109 patients (76.5%men) aged 18-64 yearswho startedmedical day treatment between 1997 and 2006were recruited. Deaths weremonitored until the end of 2006 using a nationalmortality register. Standardizedmortality ratios (SMR) by age and gender and population attributable risks (PAR) by age group were estimated. Results: There were 557 deaths (83% were men). The total excess mortality was 8 times higher than in the general population aged 18-64 years, especially in the group aged 25-34 years old (SMR: 11.2 [95% CI: 7.8-16.0] in men and 24 [IC95%: 11.5-50.4] in women). Signi?cant differences by gender were found in all the variables analyzed. In Barcelona, alcohol use disorder was estimated to cause 73 deaths per year, representing 3.3% of the total annual deaths in this city in persons aged 18-64 years. This percentage was substantially higher in the groups aged 25-34 years (PAR: 19.4% [95% CI: 19.2-19.6]) and 18-24 years (PAR: 11.1% [95% CI: 10.7-11.4]). Conclusions: Women and young men with an alcohol use disorder have a higher risk of early mortality. Early detection of problematic alcohol consumption and selective and well-indicated prevention programs should be improved. © 2010 SESPAS. Source

Morales-Suarez-Varela M.,University of Valencia | Morales-Suarez-Varela M.,CIBER ISCIII | Morales-Suarez-Varela M.,Center for Public Health Research | Gonzalez-Candelas F.,CIBER ISCIII | And 30 more authors.
Maternal and Child Health Journal | Year: 2014

The aim of this study was to investigate the main characteristics of non-vaccinated pregnant women who were hospitalised for influenza A (H1N1) pdm09 pandemic versus pregnant women hospitalised for non-influenza-related reasons in Spain, and to characterise the clinical presentation of the disease in this population to facilitate early diagnosis and future action programmes. Understanding influenza infection during pregnancy is important as pregnant women are a high-risk population for increased morbidity from influenza infection. We investigated the socio-demographic and clinical features of 51 non-vaccinated, pregnant women infected with the pandemic influenza A (H1N1) virus in Spain (cases) and compared them to 114 controls (non-vaccinated and non-infected pregnant women) aged 15-44 years. Substantial and significant odd ratios (ORs) for pandemic influenza A (H1N1) were found for the pregnant women who were obese compared with controls (body mass index > 30) (OR 3.03; 95 % confidence intervals 1.13-8.11). The more prevalent symptoms observed in pandemic influenza-infected pregnant women were high temperature, cough (82.4 %), malaise (80.5 %), myalgia (56.1 %), and headaches (54.9 %). Our results suggest that the initial symptoms and risk factors for infection of pregnant women with the influenza A (H1N1) pdm09 virus are similar to the symptoms and risk factors for seasonal influenza, which make early diagnosis difficult, and reinforces the need to identify and protect high-risk groups. © 2013 Springer Science+Business Media New York. Source

Herrero M.J.,Imim Institute Of Recerca Of Lhospital Del Mar | Domingo-Salvany A.,Imim Institute Of Recerca Of Lhospital Del Mar | Domingo-Salvany A.,CIBER ISCIII | Brugal M.T.,CIBER ISCIII | And 2 more authors.
Journal of Substance Abuse Treatment | Year: 2011

A prospective study was carried out in Barcelona, Spain, to determine the incidence of mental disorders including substance use disorders (SUDs). From a cohort of 288 young adult (aged 18-30 years) cocaine and/or heroin users recruited in nonclinical settings, 158 were reinterviewed 18 months later using the Psychiatric Research Interview for Substance and Mental Disorders. During follow-up, 18% of subjects presented a new SUD, and nearly 11% a new non-SUD Axis I disorder. Incidence was highest for mood disorders (8%). Being a woman, a lower frequency of substance use at baseline, a younger age of heroin first use, and a worsening of SUD were associated with a higher likelihood of presenting a new Axis I disorder. Having received drug treatment ever (at baseline) or during follow-up was not associated with progress of SUD. An overall improvement in the psychiatric status of these young substance users was observed. © 2011 Elsevier Inc. Source

Toledo F.O.,University of Sao Paulo | Barros P.S.,University of Sao Paulo | Herdman M.,Imim Institute Of Recerca Of Lhospital Del Mar | Vilagut G.,Imim Institute Of Recerca Of Lhospital Del Mar | And 5 more authors.
Journal of Pain and Symptom Management | Year: 2013

Context: Chronic pain is a common complaint among patients with muscular disease. The Wisconsin Brief Pain Questionnaire (WBPQ) has been used to quantify pain severity and pain interference with daily functions. Objectives: To translate the WBPQ for use with Brazilian patients and to evaluate the psychometric properties of the adaptation. Methods: We conducted a cross-cultural adaptation of the original English version of the WBPQ for use in Brazil (WBPQ-B) and evaluated the psychometric properties of the adapted version. The original questionnaire was translated, evaluated by an expert panel, pilot tested in 40 patients, and back-translated. Subsequently, the tool was administered, in a cross-sectional study, to 100 adult patients who had muscular disease and were being attended to at our university hospital. Results: We performed a confirmatory factor analysis and assessed the reliability and validity of the questionnaire (Appendix). The two-factor structure (pain intensity and pain interference) was confirmed satisfactorily. Internal consistency for both scales was adequate (Cronbach's alpha = 0.74 and 0.79, respectively), as was the interrater stability (intraclass correlation coefficients = 0.88 and 0.92, respectively). Convergent validity with the 36-Item Short Form Health Survey was supported by confirmation of a priori hypotheses of negative and satisfactory correlations between the WBPQ-B and some of the 36-Item Short Form Health Survey domains. The pain interference scale correlated higher with the mental summary component. Known-group validity analysis showed that the pain intensity items and scale of the WBPQ-B were higher in the groups where patients with exercise intolerance were concentrated. Conclusion: We found the WBPQ-B to be a reliable and valid instrument for pain assessment of Brazilians who have muscular disease. The survey presents similar psychometric properties to the original version. © 2013 U.S. Cancer Pain Relief Committee.Published by Elsevier Inc. All rights reserved. Source

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