Deshmukh S.K.,TERI University |
Prakash V.,IILM Academy of Higher Learning |
Ranjan N.,TERI University
Phytochemistry Reviews | Year: 2017
Fungal endophytes have marked a significant impact on drug discovery reducing the burden and dependency on plants. The vast diversity of Pestalotiopsis sp. has emerged as promising source of wide range of bioactive natural compounds. Recently a series of numerous novel secondary metabolites have been discovered of which taxol has drawn attention of scientific community towards its medicinal potential. A wide variety of compounds like alkaloids, polyketides, terpenoids, flavonoids, coumarins, xanthones, quinones, semiquinones, peptides, phenols, phenolic acids, and lactones have been identified which have usage as antimicrobial, antifungal, antiviral antoneoplastic, and antioxidant activities. This review aims to highlight recent discoveries of different strains of Pestalotiopsis identified for producing natural bioactive compounds along with insights of their source of origin and potential in biotechnological applications. © 2017 Springer Science+Business Media Dordrecht
Prakash V.,IILM Academy of Higher Learning
Asian Journal of Pharmaceutical and Clinical Research | Year: 2017
Terpenoids accounts for the major class of secondary metabolites produced by plants. It shows defense activity against environmental stress and help to heal injuries. Medicinal plants are rich in monoterpenoids, diterpenoids, sesquiterpenes, triterpenes, tetraterpenes, and ceramide. A number of therapeutic applications such as antibacterial, antimicrobial, antitumor, anti-inflammatory activity have been identified. Terpenoids are compounds similar to terpenes derived from 5-carbon monomer isoprene units. The review puts and detail insight on different class of compounds isolated from natural source from 2000 to 2016 showing anti-inflammatory potential of pharmacologically interesting agent and their mechanism of action. © 2017 The Authors.
Yadav A.K.,Jamia Millia Islamia University |
Singh S.,IILM Academy of Higher Learning |
Gupta G.,Amity University |
Ghosh U.,IILM Academy of Higher Learning
Advanced Science Letters | Year: 2014
Betterment of standard of Living and industrialization leap up the pressure on the conventional sources of power. Depletion of conventional sources becomes a problem in present world. And ever rising cost of conventional fuel may be major impediment in economic and social growth of third world nations. So keeping in mind this present situation we have come up with a new concept of generating electricity through steps. The concept is that as we walk up or down on the stairs electricity is produced. This paper attempts to show how energy can be tapped and used at a commonly used floor steps. The usage of steps in every building is increasing day by day, since even every small building has some floors. A large amount of energy is wasted when we are stepping on the floors by the dissipation of heat and friction, every time a man steps up using stairs. There is great possibility of tapping this energy and generating power by making every staircase as a power generation unit. The generated power can be stored by batteries, and it will be used for lighting the building. For this purpose we are using lead screws, stepper motors to generate electricity and pair of capacitor to store the current and discharge it when it is needed. With performed some experiments and we found that the current produced with a single step action is 1.70 mA and the efficiency calculated is 85%. We will be able to produce a large amount of current on a larger scale which would be enough for our daily usage without depleting our natural resources and producing low cost electricity. © 2014 American Scientific Publishers. All rights reserved.
Parashar P.P.,IILM Academy of Higher Learning |
Parashar P.P.,Mangalore University
Recent Patents on Materials Science | Year: 2013
The present paper reviews recent patents on polymer-inorganic particle blends with reference to silver particulate films on softened polymer composites of polystyrene (PS)/ poly (2-vinyl pyridine) (P2VP) and PS/ poly (4- vinylpyridine) (P4VP) deposited at a rate of 0.4 nm/s held at a temperature of 457 K in vacuum of 8×10-6Torr by evaporation. There has been continuous development in the field of polymer-inorganic nano particle blends. Polymer-inorganic particle blends are incorporated into structures involving interfaces with additional materials can be used for forming desirable devices. Polymer blends with a vast variety of characteristics, architectures with properties that are often not accessible with individual components are prepared. A method is used to form metal nanoparticles having a desired shape and size by combining in a single solution, solvent, metal ions and copolymers under conditions such that metal nanoparticles are formed. Nanoparticles layers can be distributed on a substrate using various methods. Blending of insulating polymers with metal particle provides an insulating cover and cost reduction. Various methods are used to design nanoparticle on a dielectric substrate for desired applications like charge storage in electronic devices, system and optical sensors. © 2013 Bentham Science Publishers.
Parashar P.,IILM Academy of Higher Learning
Advanced Materials Research | Year: 2013
Dispersing silver nanoparticles homogeneously into a polymer matrix by ex situ methods is difficult because of the easy agglomeration of nanoparticles. Therefore, convenient and effective ways of preparing Ag nanoparticles in polymer materials are still in strong demand. Vacuum deposited thin discontinuous silver films on the composite of Poly (vinylpyrrolidone) (PVP) and poly (4-vinylpyridine) (P4VP) is an in situ and eco friendly method. Films on softened PVP give rise to a very high room temperature resistance approaching that of the substrate resistance indicating non uniform formation of silver clusters. On the other hand, films on softened P4VP gives rise to a room temperature resistance in the range of a few tens to a few hundred MΩ, which is desirable for device applications due adequate size and uniform dispersal of silver clusters in P4VP. Silver films on PVP/P4VP blend show room temperature resistances in the desirable range indicating uniform subsurface formation of silver films on PVP/P4VP. The Electrical, optical and plasmonic response of Ag NP onto thin layers of PVP/P4VP shows encapsulation of nanoparticles. Silver nanocomposite film exhibits characteristic UV absorbance spectrum at a wavelength of 430 nm, due to the surface plasmon resonance of nanosized silver. Silver ions being bioactive killed bacteria on infected wounds on living tissue and led physician to use wound dressing containing silver sulfadiazine and Ag NP to treat external infections. Silver lining food helps in treating various remedies and ailments. © (2013) Trans Tech Publications, Switzerland.
Ali W.R.,IILM Academy of Higher Learning |
Prasad M.,Indian Central Electronics Engineering Research Institute
Microsystem Technologies | Year: 2015
The purpose of the paper is to design and fabricate a ZnO-based MEMS acoustic sensor for higher sound pressure level (SPL) measurement in the range of 120–200 dB and low frequency infrasonic wave detection. The thickness of silicon diaphragm was optimized for higher SPL using MEMS-CAD-Tool COVENTORWARE. The microtunnel which relates the cavity to the atmosphere was designed and simulated analytically for low cut-off frequency of the sensor in infrasonic band. The resonance frequency of the sensor was obtained using modal analysis. The sensitivity of the sensor was also estimated using COVENTORWARE. The optimized Si-diaphragm thickness for the intended SPL range was determined and found to be 50 μm. The lower cut-off frequency of the sensor for a 10 μm-deep microtunnel was found to be 0.094 Hz. The resonance frequency of the sensor was obtained using modal analysis and found to be 78.9 kHz. Based on simulation results, the MEMS acoustic sensor with 10 μm-deep microtunnel was fabricated. The optimum sensitivity of sensor was calculated using simulated results and found to be 116.4 μVolt/Pa. The lower cut-off frequency of the sensor can be utilized to detect low frequency sounds. The high SPL sensing capability of the device up to 200 dB facilitates detection of high sound pressure level in launch vehicles, rocket motors and weapons’ discharge applications. © 2014, Springer-Verlag Berlin Heidelberg.