Time filter

Source Type

Patna, India

Pandey V.,Banaras Hindu University | Gangopadhyay A.N.,Banaras Hindu University | Gupta D.K.,Banaras Hindu University | Sharma S.P.,Banaras Hindu University | Kumar V.,IGIMS
Indian Journal of Thoracic and Cardiovascular Surgery | Year: 2015

Introduction: Video-assisted thoracoscopic surgery (VATS) is a less invasive and preferred modality for early stages of empyema (American Thoracic Society, Am Rev Respir Dis 85:935–6, 1962). Still, in the late organising phase, thoracotomy and decortication is the treatment of choice (American Thoracic Society, Am Rev Respir Dis 85:935–6, 1962). We aimed to evaluate the results of decortications through muscle-sparing axillary skin crease incision (MSASCI) in paediatric empyema thoracic. Methods: A prospective study was conducted between July 2011 and June 2013 including 28 patients of empyema thoracic in late organising phase. Decortication was performed through MSASCI in all cases. Utility of incision was assessed in terms of intra-operative exposure, access to all the lobes, size and visibility of scar. Result: Adequate exposure was possible in all cases. Complete excision of thickened parietal pleura with stripping of visceral peel was possible in all the cases with the release of entrapped lung. A chest tube was removed after a mean of 6.67 ± 4.62 days (5–14 days). Three patients had air leak. There were no other complications. All children had good lung expansion on chest radiography at 4 weeks. Scar was hardly visible in normal position in follow up. Conclusion: Muscle-sparing axillary skin crease incision is a good alternative to classical thoracotomy for decortication in paediatric age group for patients with organised empyema. © 2015, Indian Association of Cardiovascular-Thoracic Surgeons. Source

Shraddha J.,JNMC | Priya M.,IGIMS | Sunil K.,JNMC
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2013

We report a case of melanocarcinoma of sino-nasal region in a 42 year old female who presented with brownish-colored sino-nasal mass involving left orbit, spontaneous epistaxis, facial swelling on left side, and ulceration of overlying skin, cervical and distant metastasis in liver over a short time span of 3 months. On biopsy, the mass was diagnosed as melanocarcinoma of nose and paranasal sinuses. Primary mucosal malignant melanoma of the nasal cavity, paranasal sinuses, and nasopharynx is an aggressive disease and fortunately rare with current research data being mainly from western populations. The disease is known to be more common among elderly population in their seventies and to follow a prolonged course due to innocuous symptoms. This case is being reported for its rarity in our geographical region, early age of presentation and rapid progression of the disease over a span of 3 months. © 2012 Association of Otolaryngologists of India. Source

Anand U.,Paras HMRI Hospital | Pandey M.K.,Paras HMRI Hospital | Priyadarshi R.N.,IGIMS | Kumar R.,Paras HMRI Hospital | Chaudhary B.,AIIMS
Journal of Clinical and Diagnostic Research | Year: 2015

Tubullo-villous adenoma of duodenum is a rare entity. These are potentially malignant tumours and therefore, complete excision is the treatment of choice. However, at times preoperative diagnosis could not be always achieved posing difficulty in choosing the optimal surgical method of excision. We report a 40-year-old male patient presented with vague upper abdominal pain and vomiting for last 6 months. His computed tomography and endoscopy demonstrated intraluminal polypoidal mass. Endoscopic biopsies were negative for malignancy. Local surgical excision with tumour free margin was performed and histology revealed tubullo-villous adenoma. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source

Kumar S.,SRMSIMS | Pathak A.K.,IGIMS | Saikia D.,AIIMS | Kumar A.,SRMSIMS
Journal of Clinical and Diagnostic Research | Year: 2015

Introduction: Metformin is a preferred drug for starting treatment in type 2 diabetes mellitus. But, eventually most of the patients need additional drug to control blood sugar level. The choice of drug depends upon several factors including patient specific criteria, economical factors and treatment satisfaction. Aim: The aim of the present study is to investigate the effects of adding sitagliptin or glimepiride on efficacy, safety and treatment satisfaction in patients with type 2 diabetes mellitus. Materials and Methods: It was a retrospective observational study on 50 patients each in sitagliptin and glimepiride group, who are receiving treatment for at least 12 weeks and are stable on respective treatment regimen. Glycated haemoglobin (HBA1c) was the primary measure of efficacy. Safety was assessed by checking weight gain/loss, hypoglycaemia episodes and other laboratory investigations. Patient satisfaction was assessed by Diabetes Treatment Satisfaction Questionnaire. Results: The HbA1c level after 12-24 weeks of treatment was not found to be significant compared to each other or from baseline. Compared to baseline fasting plasma glucose & postprandial plasma glucose were lower in glimepiride group. Sitagliptin was associated with less episodes of hypoglycaemia. Weight gain was associated with glimepiride but it was non-significant (p=0.08). Overall treatment satisfaction score were better for sitagliptin but were not statistically significant. Conclusion: The efficacy of sitagliptin was comparable. Sitagliptin had superior adverse effect profile with less chances of hypoglycaemia and weight gain. Questionnaire scores were higher for sitagliptin indicating better treatment satisfaction compared to glimepiride. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source

Priyadarshi R.N.,IGIMS | Anand U.,Paras HMRI Hospital | Pandey M.K.,Paras HMRI Hospital | Chaudhary B.,AIIMS | Kumar R.,Paras HMRI Hospital
Journal of Clinical and Diagnostic Research | Year: 2015

Gartric lipomas are rare. They are mostly small in size, and usually remain asymptomatic. We report a case of giant (14×11cm) gastric lipoma in a 46-year-old male who presented with features of gastric outlet obstruction clinically mimicking gastric malignancy. Upper endoscopy showed a large smooth polypoid mass with broad base arising from posterior wall of gastric antrum with areas of superficial ulcerations. Multiple endoscopic biopsy specimens were nondiagnostic. A computed tomography (CT) scan of the abdomen revealed a huge cauliflower- like intraluminal mass with lobulated surface projecting into gastric lumen and pyloric canal. The mass demonstrated uniform fat density consistent with lipoma. The case is presented to stress the diagnostic problems related to this condition, and emphasize the role of CT in arriving at a correct diagnosis of lipomatous gastrointestinal tract tumours. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved. Source

Discover hidden collaborations