Edo State, Nigeria
Edo State, Nigeria

Igbinedion University Okada, established in 1999, is t private university in Nigeria. Located at Okada Wonderland in Okada, a town beside Benin City, Edo state. The university was founded by Sir Gabriel Osawaru Igbinedion CFR, a billionaire, philanthropist and a local leader.The university operates on a collegiate system of tertiary education. It has accredited faculties and courses in Law, Medicine, Natural and Applied science, Business and Management Studies, Pharmacy, Engineering and the Arts and Social science. It has an enrollment of about 5000 students and is supervised by the Vice Chancellor, Prof. Eghosa Osaghae. It also offers postgraduate courses in professional fields like law, accounting etc. The University has recorded several landmark achievements including being the first private university to produce medical doctors. In 2006, a student of the university, Mr Sunday Damilola Olawuyi obtained a First Class Honours degree in the highly competitive Nigerian Bar examinations, thereby making the university the only private university in Nigeria to have achieved that feat.Igbinedion University, Okada has devoted to developing and strengthening the academic programmes offered in the various colleges to meet international standards and preparing them for accreditation by the National Universities Commission , the federal agency that has responsibility for quality assurance and maintenance of standards, and the relevant national regulatory professional bodies. The latter bodies include the Medical and Dental Council of Nigeria, MDCN , Council of Legal Education , Council for the Regulation of Engineering in Nigeria, COREN , Computer Professional Council of Nigeria , and Institute of Chartered Accountants of Nigeria, ICAN . The accreditation of all the programmes including medicine, law, engineering and accounting by these bodies confirms the high quality of academic programme offered by the varsity. Also, more than 60% of its first degree graduands yearly, proceed for postgraduate studies abroad with high success rate and commendation according to its Vice Chancellor during the institution's convocation ceremony in November, 2013.Quite early in its life, and in line with its vision of being an internationally competitive university, IUO identified external linkages and networking with universities and development partners as strategic to the realization of its goals. By March 2007, the university had established linkages with the University of Westminster in the areas of staff development, diplomatic studies and ICT and Howard University, USA , and was finalizing an exchange programme with East Carolina University in the area of global development. The university was admitted into full membership of the Global University Network for Innovation, GUNI, based in Barcelona, Spain, the European Association for International Education, EAIE, and the Network Towards Unity for Health amongst other external affiliations. It was also part of the Consortium of Development Partnerships, CDP, a conglomerate of universities, research institutions, governments and development partners in North America, Europe and West Africa. IUO’s Centre for Presidential Studies coordinated and continues to coordinate Module 8 of the CDP’s project on Local Contexts of Conflict and Peace-building in West Africa that involves researchers from Ghana, Mali, Côte d'Ivoire, Senegal, the Netherlands and Nigeria. Wikipedia.

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Daramola O.-O.I.,Igbinedion University Okada
Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria | Year: 2015

The effects of T. occidentalis seed oil on some female reproductive indices were investigated in Wistar rats. The study was divided into two phases: (estrous cycle and pregnancy). Animals were grouped into four: group A received distilled water (control), groups B, C and D received 400, 600 and 800 mg/kg bw of T. occidentalis seed oil respectively. The pattern of estrous cycle was determined for three weeks before and during the treatment. Thereafter, each group was sub- divided into two. The sub-group-1 rats were mated with male breeders, the litter size and birth weight of their offsprings was determined. Sub-group-2 rats were sacrificed and histology of organs and serum levels of LH, FSH and estrogen were assayed. There was no significant difference between the pre-treatment and post-treatment estrous cycle length. However, there was a significant decrease in the frequency of diestrus phase during treatment in all the experimental groups when compared with pre-treatment period but there was no significant difference in the diestrus phase when compared with the control group. Serum estrogen concentration was significantly reduced in the group that was treated with 800 mg/kg bw of T. occidentalis seed oil. Histology of the ovary and uterus in the experimental groups were similar to that of the control group. Birth weight of pups was significantly increased in the group treated with 600 mg/kg bw of T. occidentalis seed oil when compared with the control group. The results of this study suggest that T. occidentalis seed oil does not alter estrous cycle in Wistar rats.

Olagbuji B.N.,University of Benin | Ezeanochie M.C.,University of Benin | Ande A.B.,University of Benin | Oboro V.O.,Igbinedion University Okada
Archives of Gynecology and Obstetrics | Year: 2010

Purpose: To compare the outcome of pregnancy between HIV positive pregnant women on highly active antiretroviral therapy (HAART) and HIV negative controls. Methods: A prospective matched case-control study. Results: HIV positive women were significantly more likely to have anaemia in pregnancy [p < 0.001, odds ratio (95% CI) 5.66 (3.0-10.5)], intrauterine growth restriction [p = 0.002, odds ratio (95%CI) 13.82 (1.8-106.7)], preterm labour [p = 0.03, odds ratio (95% CI) 2.89 (1.2-7.0)] and birth weight less than 2,500 g [p < 0.0001, odds ratio (95% CI) 5.43 (2.4-12.0)]. The 5-min apgar score less than 7, admission into neonatal unit, stillbirth and perinatal mortality were comparable between the two groups. Conclusion: Anaemia in pregnancy, intrauterine growth restriction, preterm labour and birth weight less than 2,500 g are important complications among HIV positive pregnant women. This information is vital for strategic antenatal care planning to improve obstetric and perinatal outcome in these women. © 2009 Springer-Verlag.

Henry Oladeinde B.,Igbinedion University Okada | Omoregie R.,University of Benin | Olley M.,Igbinedion University Okada | Anunibe J.A.,Igbinedion University Okada
North American Journal of Medical Sciences | Year: 2011

Aim: To determine the prevalence of urinary tract infection (UTI) in Okada, a rural community in Nigeria, and the effect of age and gender on its prevalence as well as the etiologic agents and the susceptibility profile of the bacterial agents. Patients and Method: Clean-catch midstream urine was collected from 514 patients (49 males and 465 females). The urine samples were processed and microbial isolates identified. Susceptibility testing was performed on all bacterial isolates. Result: The prevalence of urinary tract infection was significantly higher in females compared to males (female vs. male: 42.80% vs. 10.20%; OR = 6.583. 95% CI = 2.563,16.909; P < 0.0001). Age had no effect on the prevalence of UTI. Escherichia coli was the most prevalent isolate generally and in females, while Staphylococcus aureus was the predominant isolate causing urinary tract infection in males. The flouroquinnolones were the most active antibacterial agents. Conclusion: An overall prevalence of 39.69% was observed in this study. Females had a 3 to 17 fold increase risk of acquiring UTI, than their male counterpart. Escherichia coli were the predominant isolates causing UTI.

Anetor J.I.,Igbinedion University Okada | Anetor J.I.,University of Ibadan
Nigerian Journal of Physiological Sciences | Year: 2012

TCadmium (Cd) is a ubiquitous environmental pollutant of increasing worldwide concern. It is thought to be of greater concern to rapidly industrializing developing countries because of the increasing pace of industrial activities in these countries with increasing consumption and release into the environment. Traditionally, health concerns in exposed human populations have revolved around the association of Cd with bone disease, emphysema and possibly hypertension. Accumulating evidence suggest that Cd is involved in the disruption of many genomic processes, the mechanisms of which are being gradually understood. Changes in DNA Methylation may be induced by cadmium leading to epigenetic alterations. Additionally, though Cd is not thought to induce reactive oxygen species (ROS) directly because it is not capable of accepting or donating electrons under physiological conditions, 8-hydroxy deoxyguanosine (8-OHdG) (a marker of oxidative stress to DNA and a risk factor for cancer among others) has been shown to be elevated in the DNA of testes from rats treated with cadmium chloride, at least in part because Cd inhibits DNA repair mechanisms. Cadmium is also a metabolic antagonist to Zinc (Zn), an important micronutrient involved in numerous molecular activities. This antagonism alters the physiological stoichiometric relationship between Cd and Zn leading to high Cd/Zn ratio, one consequence of which is high error rate and lack of efficient DNA repair systems leading to high mutation and genome instability culminating in many carcinogenic states, particularly prostate carcinogenesis. Cadmium has also been shown to replace Zn in the tumor suppressor protein, p53 thereby impairing p53's DNA binding activity and associated repair processes. The expression of the p53 protein is significantly depressed by cadmium. Although the rising level of Cd in the environment is widely acknowledged, the occult threat it poses to genome stability largely through inhibition of normal DNA damage repair, oxidative stress and apoptosis and health is poorly recognized. This paper examines the involvement of Cd in the molecular pathways of human disease, providing insight for the prevention of genome instability and associated disease susceptibility particularly cancer across populations through micronutrient intervention, aiding upregulation of the antioxidant defense and DNA repair systems. © Physiological Society of Nigeria.

Adejoh S.O.,University of Lagos | Olorunlana A.,Igbinedion University Okada
Journal of Cancer Education | Year: 2016

Breast cancer is ranked second as the cause of cancer death among women. Of importance to the management of breast cancer is the interaction processes between the patients and their professional caregivers or healthcare providers. Against this background, this study explores the experiences of Nigerian women as breast cancer patients and their interaction with their caregivers in the management of their condition. The study was cross-sectional in design. Twenty diagnosed breast cancer patients participated in the study and were purposively selected using convenience and snow balling sampling technique. Patients affirmed that they were initially afraid when diagnosed but overcame their fear based on caregivers’ supports. Physical interactions and the use of mobile phones were common means of communication while the fear of death and financial burden of the disease were of major concerns to the patients. The majority of the patients were satisfied with the quality of care and treatment received in the private hospitals as they were encouraged and supported. It was discovered that professional caregivers are germane to patients’ survival from shock and adequate information on how to manage their condition and live a normal life. © 2016 American Association for Cancer Education

Mirabeau T.Y.,Niger Delta University | Samson E.S.,Igbinedion University Okada
African Journal of Traditional, Complementary and Alternative Medicines | Year: 2012

Extracts of some spices have been reported to play a contributory role in enhancing immune function. We evaluated and compared the effect(s) of single and combined oral administration of fresh aqueous onion (Allium cepa) and garlic (Allium sativum) extracts at different concentrations on some immunological determinants in rats. CD4 cells of the rats were estimated using Partec flow cytometric technique, while total and differential white blood cell (WBC) counts were estimated using the Sysmsex® automated haematology analyzing technique. Our findings revealed that, CD4 and total WBC counts were significantly increased (P≤0.05) in a dose-dependent manner in both onion (250mg/Kg/d: 349±11cell/ul and 2.75±0.15X103cell/l; 500mg/Kg/d: 389±10cells/μl and 3.05±0.05 X103cell/l; 750mg/Kg/d: 600±11cell/μl and 3.25±0.05X103cells/l) and garlic (250mg/Kg/d: 410±10cell/ul and 2.85±0.15X103cell/l; 500mg/Kg/d: 494±32cells/μl and 3.30±0.10 X103cell/l; 750mg/Kg/d: 684±11cell/μl and 3.55±0.05X103cells/l) treated rats when compared to the zero control (200±11cells/μl and 1.55±0.05X103cells/l, respectively). Extract of garlic at 750mg/Kg/d had significantly increased the CD4 cells and total white cell count when compared to other concentrations (P≤0.05). However, no significant effect was observed on these parameters when extracts were combined (250mg/Kg/d: 252±21cell/μl and 1.80±0.10X103cells/l; 500mg/Kg/d: 315±21cells/ul and 2.10±0.10X103cells/l; 750mg/Kg/d: 368±10cells/μl and 2.35±0.05X103cells/l, respectively), the differential WBC count showed a significant increase in the proportion of cell types (lymphocytes, neutophils and monocytes) (P≤0.05). The results from this study revealed the immune boosting capabilities of Allium cepa and Allium sativum, but underscored their synergistic activities. © African Journal of Traditional, Complementary and Alternative Medicines.

Amoran O.E.,Olabisi Onabanjo University | Senbanjo I.O.,Lagos State University | Asagwara C.E.,Igbinedion University Okada
BMC Public Health | Year: 2011

Background: The Africa Malaria Report shows that many countries are quite far from reaching the universal coverage targets of 80% coverage by 2010 and maintain it at this level. This paper examines ITN use and the factors associated with its adoption among the youths in Nigeria. This information will help in the design of effective methods of providing and distributing the nets in order to enhance its adoption and maximize the public health benefits of ITNs. Methods. This cross-sectional survey was carried out in 2006 among university leavers serving compulsory national service (youth corpers) using total sampling technique. The study was conducted using a self-administered questionnaire. Results: A total of 656 youth corp members were interviewed. Only 23.8% of these youths ever use ITN while 4.3% currently use ITN before reporting in camp. A significant proportion of the youths acquired information on ITN from Mass Media (p = 0.0001). Other statistically significant factors that encourage the use of ITN include inexpensive market price of ITN (p = 0.0001), frequency of Malaria infestation (p = 0.019) and perceived malaria preventive action of ITN (p = 0.000). Following logistic regression analysis, perceived effective malaria preventive action of ITN [OR = 29.3, C.I = 17.17-50.0] and high frequency of Malaria infestation [OR = 1.55, C.I = 0.97-2.47] were predictors of ITN use. Conclusion: The study shows that the use of ITN for the prevention of Malaria is low among these Nigerian youths. The major factors determining the adoption of ITN among the youths were perceived effective Malaria prevention action of ITN and high frequency of Malaria attack. These factors should be considered in the design of sustainable and effective locally relevant strategies for scale-up adoption of ITNs among a youthful African population. © 2011 Amoran et al; licensee BioMed Central Ltd.

Ojo G.U.,Igbinedion University Okada
Local Environment | Year: 2014

A notable feature of development aid since the 1960s has been a paradigm shift from centralised project planning and management to decentralised approaches. The transition from top-down to bottom-up elevates the concept of localism in project management for vulnerable groups. This change resonates well in community-based resource management schemes in privileging the locale in terms of generation of knowledge and how problems and remedies are enunciated. Localism conceptualised as devolving central-level government functions to non-state actors in social service delivery is contradictory and seems to negate state powers. This paper explores this trajectory to explicate the forms of localism and the contradictions from its multiple conceptualisations that influence energy access. Using qualitative methodology and interviews, it analyses renewable energy projects directed at poverty alleviation in rural communities in Nigeria while deploying a political ecology framework of power relations to highlight the dynamics of localism. While localism is touted as a constraint in the development process due to localism of action, the paper demonstrates its prospects and how scaling-up of operations may augur well for altering its conceptualisation and with far-reaching consequences for community sustainable energy projects. © 2013 © 2013 Taylor & Francis.

Ojo G.U.,Igbinedion University Okada
Singapore Journal of Tropical Geography | Year: 2012

Since its emergence as a research field in the 1980s, political ecology has provided a useful tool to explicate violent environments, notably as hallmarks of natural resource-dependent economies. Practitioners regularly address what might be called 'charismatic' natural resources such as oil and other precious minerals to describe contestation over access and control of natural resources. Yet, where this focus exists, the political ecology of less economically valuable or 'noncharismatic' resources is thereby obscured. Thus, Nigeria's dependency on oil production has generated much scholarly attention with its unstable political economy described as a rentier state. In contrast, this paper draws on extensive field experience and knowledge about the country to assess in a preliminary manner some of the dimensions and ramifications of a less well known second-tier natural resource commodity that is gaining attention as part of a possible national economic diversification strategy. Using the case of bitumen, a viscous hydrocarbon mainly used in road surfacing and roofing work, I assess the trajectory of this relatively overlooked resource, thereby opening a window onto the political ecology of a noncharismatic resource. In contrast to the ubiquitous violence in the oil-based Niger Delta, I suggest that bitumen political ecologies, while also provoking political conflict and debate, nonetheless seem to being marked by new power dynamics that might augur a less violence prone path in terms of Nigeria's political economy of natural resource production. © 2012 The Author. Singapore Journal of Tropical Geography © 2012 Department of Geography, National University of Singapore and Blackwell Publishing Asia Pty Ltd.

Ajeigbe K.O.,Igbinedion University Okada
African journal of traditional, complementary, and alternative medicines : AJTCAM / African Networks on Ethnomedicines | Year: 2013

Several medicinal plants have been documented for their haematological effects either at low or high concentration but very little is known about Aspilia africana. The aim of the study was to investigate the acute effects of aqueous leaf extract of Aspilia africana at different concentrations on some haematological parameters in rats. Following 14 days of oral administration of aqueous extract of A. africana, Haematocrit (HCT), Haemoglobin concentration (HB), Mean Cell Haemoglobin Concentration (MCHC), Red Blood Cell Count (RBC Count), Total White Blood Cell Count (Total WBC Count), Absolute Neutrophils count (NEUT#), Absolute Lymphocytes count (LYM#), Absolute Eosinophils Count (EOSIN#) and Absolute Monocytes (MONO#) were evaluated in twenty (20) male Wistar albino rats. The rats weighed 174 ± 20 g, and were randomly assigned into 4 groups viz: Group 1, Control; Group 2, 250 mg/Kg/d aqueous extract; Group 3, 500 mg/Kg/d aqueous extract; and Group 4, 750 mg/Kg/d aqueous extract. HCT, HB, MCHC, RBC Count, Total WBC Count, NEUT#, LYM#, EOSIN# and MONO# were significantly increased (P<0.001) in 500 mg/Kg/d of A. africana extract (61.13 ± 1.65%, 13.5 ± 1.29 g/dl, 23.33 ± 0.0.02 g/dl, 3.68 ± 0.02 X 10(12)Cells/l, 2.33 ± 0.02 X 10(9)Cells/l, 1.32 ± 0.04 X 10(9)Cells/l, 1.43 ± 0.05 X 10(9)Cells/l, 0.47 ± 0.02 X 10(9)Cells/l and 0.47 ± 0.04 X 10(9)Cells/l, respectively) when compared to the Control (51.13 ± 0.85%, 9.56 ± 0.43 g/dl, 19.22 ± 0.19 g/dl, 2.69 ± 0.01 X 10(12)Cells/l, 1.79 ± 0.01 X 10(9)Cells/l, 0.80 ± 0.00 X 10(9)Cells/l, 0.83 ± 0.00 X 10(9)Cells/l, 0.18 ± 0.00 X 10(9)Cells/l and 0.24 ± 0.00 X 10(9)Cells/l, respectively) which received no extract at all. The 500 mg/Kg of A. africana extract proved to be the most effective, while the 750 mg/Kg proved to be the least effective in comparison with the control. The results of this study further strengthened the earlier works on the medicinal benefits of Aspilia africana and its virtue as a good pharmacological source of haematopoiesis.

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