Ituiutaba, Brazil
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Patel L.D.,Gujarat University | Mani M.,IFTM
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2010

The present studies reveal that the anticonvulsant activity by PTZ and MES induced convulsions in wistar rats using Abutilon indicum leaf ethanolic (AIE) and aqueous (AIA) extracts extracted successively. The presence of alkaloids, glycosides, carbohydrates, steroids, tannins, phenolic compounds, proteins, amino acids, saponins, flavonoids, terpenoids, gums and mucilages in both the extracts. 100 mg/kg and 400 mg/kg of AIE and AIA were given orally. The latency of seizures, death time and % of mortality were observed. AIE gave significant protection against the PTZ (pentylene tetrazole) and MES (maximal electro shock) induced convulsions. The p value in PTZ is p ≤ 0.01 and MES, p ≤ 0.01 and p ≤ 0.001.

Martins R.G.,IFTM | Martins R.G.,Federal University of Uberlandia | Martins A.S.,IFTM | Neves L.A.,São Paulo State University | And 3 more authors.
Expert Systems with Applications | Year: 2017

Football is the team sport that mostly attracts great mass audience. Because of the detailed information about all football matches of championships over almost a century, matches build a huge and valuable database to test prediction of matches results. The problem of modeling football data has become increasingly popular in the last years and learning machine have been used to predict football matches results in many studies. Our present work brings a new approach to predict matches results of championships. This approach investigates data of matches in order to predict the results, which are win, draw and defeat. The investigated groups were different type of combinations of two by two pairs, win-draw, win-defeat and draw-defeat, of the possible matches results of each championship. In this study we employed the features obtained by scouts during a football match. The proposed system applies a polynomial algorithm to analyse and define matches results. Some machine-learning algorithms were compared with our approach, which includes experiments with information obtained from the football championships. The association between polynomial algorithm and machine learning techniques allowed a significant increase of the accuracy values. Our polynomial algorithm provided an accuracy superior to 96%, selecting the relevant features from the training and testing set. © 2017 Elsevier Ltd

Tambasco Bruno D.O.,Federal University of ABC | Do Nascimento M.Z.,Federal University of ABC | Do Nascimento M.Z.,Federal University of Uberlandia | Ramos R.P.,UNIVASF CENEL | And 3 more authors.
Expert Systems with Applications | Year: 2016

In computer-aided diagnosis one of the crucial steps to classify suspicious lesions is the extraction of features. Texture analysis methods have been used in the analysis and interpretation of medical images. In this work we present a method based on the association among curvelet transform, local binary patterns, feature selection by statistical analysis and distinct classification methods, in order to support the development of computer aided diagnosis system. The similar features were removed by the statistical analysis of variance (ANOVA). The understanding of the features was evaluated by applying the decision tree, random forest, support vector machine and polynomial (PL) classifiers, considering the metrics accuracy (AC) and area under the ROC curve (AUC): the rates were calculated on images of breast tissues with different physical properties (commonly observed in clinical practice). The datasets were the Digital Database for Screening Mammography, Breast Cancer Digital Repository and UCSB biosegmentation benchmark. The investigated groups were normal-abnormal and benign-malignant. The association of curvelet transform, local binary pattern and ANOVA with the PL classifier achieved higher AUC and AC values for all cases: the obtained rates were among 91% and 100%. These results are relevant, specially when we consider the difficulties of clinical practice in distinguishing the studied groups. The proposed association is useful as an automated protocol for the diagnosis of breast tissues and may contribute to the diagnosis of breast tissues (mammographic and histopathological images). © 2016 Elsevier Ltd. All rights reserved.

Srivastava R.,IFTM | Srivastava R.,Integral University | Sharma R.,Integral University | Mishra S.,IFTM | And 2 more authors.
Open Nutraceuticals Journal | Year: 2011

Oral cancer is the cancerous tissue growth located in the oral cavity. It may arise as a primary lesion originating in any of the oral tissues, by metastasis from a distant site of origin, or by extension from a neighboring anatomic structure, such as the nasal cavity or the maxillary sinus. Smoking and other tobacco use are associated with about 75 percent of oral cancer cases. Alcohol use is another high-risk activity associated with oral cancer. Infection with human papillomavirus (HPV), particularly type 16 (there are over 120 types), is a known risk factor and independent causative factor for oral cancer. Oncogenes, gain-of-function mutations of highly regulated normal cellular counterparts (proto-oncogenes), are likely involved in the initiation and progression of oral neoplasia. Cellular oncogenes were initially discovered by the ability of tumor cell DNA to induce transformation in gene transfer assays. Mechanisms of activation of these cellular oncogenes include point mutations and DNA re-arrangements. Several of these cellular oncogenes are homologs of retroviral oncogenes (e.g., the ras genes); others are new oncogenes. Tumor suppressor genes or anti-oncogenes have been documented to confer potent negative regulatory controls which are lost due to chromosomal alterations during tumor formation. Functional loss of multiple tumor suppressor genes is believed to be the major event leading to the development of malignancy. Treatment is done till date with the help of radiation therapy, considering the removal of tumor which proceeds with the surgery. Chemotherapy is also used but not to a wide extent and that too has to be done with radiation and research work is still going on the drug discovery for this disease, hence looking towards this fact we opted for the work in this area looking into the successful way of the treatment for oral cancer. The present review is compilation of the data pertaining to biochemistry and molecular biology of oral carcinoma and would certainly provide new insights to explore the development of nutraceuticals based on the hypothesis projected by future studies on computational biotechnology of oral carcinoma.

Torres J.L.R.,Federal Rural University of Rio de Janeiro | Santana M.J.,IFTM | Neto A.P.,Brazilian National Council for Scientific and Technological Development | Pereira M.G.,Brazilian National Council for Scientific and Technological Development | Vieira D.M.S.,Brazilian National Council for Scientific and Technological Development
Bioscience Journal | Year: 2013

The use of irrigation in the bean crop in the winter, grown in no tillage, are alternatives used to increase crop productivity, reduce evaporation and increase water retention capacity of the soil. This study aimed to evaluate the productivity of irrigated beans and biomass production of cover crops in Uberaba-MG. The experimental design was a randomized block in a 4×5×3 factorial, which included four types of cover crops (sunn hemp, bean-to-pig, millet and fallow), five irrigation (40%, 70%, 100%, 130% and 160% of daily crop evapotranspiration) and three repetitions. Were evaluated the dry mass of the roof at the point of maximum flowering, productivity, number of pods per plant and grains of the bean crop grown on the crop residues left by these coverages. The precipitation decisively influenced the production of dry biomass of the tested cover.The bean yield was higher when grown on millet and beans on the lower in the bean-to-pig area.

Castoldi R.,São Paulo State University | Charlo H.C.O.,IFTM | Melo D.M.,São Paulo State University | Candido W.S.,São Paulo State University | And 3 more authors.
Horticultura Brasileira | Year: 2014

Lettuce is the most consumed leafy vegetable in Brazil. Its production, nonetheless, is increasing in difficulties mainly due to the infestation of producing areas with Bremia lactucae. Thus, the use of horizontal resistant cultivars is the most viable alternative in controlling progress of disease. So, the objective of this study was to obtain resistant lettuce progenies to the races of downy mildew: SPBl:01, SPBl:02, SPBl:03, SPBl:04, SPBl:05, SPBl:06 and SPBl:07. The breeding consisted of two stages: crossover of parentals to obtain the resistant lettuce progenies and endurance test of the progeny to B. lactucae races. The parentals used to obtain progenies with resistance factor R-18 and R-38 were: JAB 4-13-7 and JAB 4-13-7. The Pedigree method was used for obtaining the progeny, using as default selections the Hortência cultivar and JAB 4-13-7genotype. After selection and selfing of the plants in the field, the resistance or susceptibility test was realized, by inoculation of the progenies from the crosses, with mixture of distilled water + sporangia of B. lactucae races SPBl:01, SPBl:02, SPBl:03, SPBl:04, SPBl:05, SPBl:06 and SPBl:07 obtained from isolates collected in the years 2008-2010. Fifteen days after inoculation, the seedlings were selected as resistant or susceptible, discarding those presenting sporulation and necrotic spots caused by B. lactucae. Through the Pedigree method we found 69 progenies F3 with good agronomic characteristics. However, after resistance or susceptibility test, only 19 showed all the plants resistant to downy mildew.

Castoldi R.,São Paulo State University | Gomes R.F.,São Paulo State University | Charlo H.C.O.,IFTM | Melo D.M.,São Paulo State University | Braz L.T.,São Paulo State University
Horticultura Brasileira | Year: 2014

The objective of this work was to evaluate the performance of three Japanese group cucumber hybrids, which were cultivated in two cultivation systems. The experiment was designed in a split-plot randomized block design with two cultivation systems (coconut fiber and soil) for commercial Japanese cucumber hybrids ('Tsuyataro', 'Yoshinari' and 'Nankyoku'). After harvesting the cucumbers, we evaluated the number of marketable fruits per plant, the average fruit length, the mean fruit diameter, the bottom fruit diameter, the marketable production of fruits per plant and the marketable yield per hectare. There were significant interactions between the cultivation system and the hybrid, as indicated by the number of marketable fruits. The Nankyoku hybrid had the highest average (14.54 fruits pl-1), although it did not differ from the Yoshinari hybrid when grown in coconut fiber. In soil culture, the Yoshinari hybrid had the highest average number of fruits per plant (10.12 fruits pl-1) and did not differ from the Tsuyataro hybrid. Cultivation in coconut fiber provided better results for production traits and plant productivity. 'Yoshinari' and 'Nankyoku' were the most productive hybrids. Based on the cucumber cultivation results from a protected environment, the cultivation of hybrid Japanese cucumbers and Yoshinari and Nankyoku hybrids in coconut fiber is recommended.

Charlo H.C.O.,IFTM | de Oliveira S.F.,São Paulo State University | Vargas P.F.,São Paulo State University | Castoldi R.,São Paulo State University | And 2 more authors.
Horticultura Brasileira | Year: 2012

The production of sweet peppers in greenhouse has been severely affected by soil pathogens. With this, producers are adopting new cultivation techniques, such as cultivation in substrates, but information about this type of cultivation are still scarce. The aim of the present work was to evaluate nutrient accumulation in sweet peppers cultivated in coconut fiber with fertirrigation in greenhouse. Initially, 160 plants (Eppo cultivar) were divided into four blocks, where two plants per block were analyzed every 21 days after transplanting. The sweet peppers were cultivated in plastic pots of 13 L, containing coconut fiber, and placed in double rows with spacing of 0.5 × 0.8 m between single rows and 1.10 m between double rows. The commercial production of the mature fruits was estimated to be 97.3 t ha-1, where all the production was classified as Extra (maximum quality). The accumulation of the various determined nutrients were: 8.22 g plant-1 of N, 1.14 g plant-1 of P, 7.84 g plant-1 of K, 3.25 g plant-1 of Ca, 1.34 g plant-1 of Mg, 2.24 g plant-1 of S, 16.65 mg plant-1 of B, 3.36 mg plant-1 of Cu, 45.98 mg plant-1 of Fe, 34.78 mg plant-1 of Mn and 22.28 mg plant-1 of Zn.

Torres J.L.R.,Instituto Federal Of Educacao E Tecnologia Triangulo Mineiro Iftm | Rodrigues Junior D.J.,Zootecnia do IFTM | Sene G.A.,Zootecnia do IFTM | Jaime D.G.,IFTM | Vieira D.M.S.,IFTM
Bioscience Journal | Year: 2012

The impact caused by cattle trampling has been implicated to cause soil compaction in areas of cultivated pastures and in those where there is the integration of crops and livestock. The objective of this study was to evaluate the influence of cattle trampling on the penetration resistance of grass in a pasture constituted Tifton 85, with and without irrigation, in Uberaba-MG. The experiment was arranged in a 2×6×4 factorial design, two treatments, consisting of area under irrigation (T1) and without irrigation (T2) with coverage of Tifton 85, six deep, with assessments every 0.10 m to 0.60 m, with four. We evaluated the mechanical resistance to penetration with an impact penetrometer, density and volumetric soil water content at depths evaluated and green mass production. Resistance to penetration was influenced by soil moisture in areas with and without irrigation, cattle trampling caused the increased density of the soil in non-irrigated, there was a positive correlation between density and moisture, the negative correlation between moisture content, density and resistance to penetration. The highest production of biomass always occurred in the irrigated area.

de Souza O.P.,Instituto Federal do Triangulo Mineiro IFTM | Zanini J.R.,São Paulo State University | Torres J.L.R.,IFTM | Barreto A.C.,IFTM | Souza E.L.C.,São Paulo State University
Bioscience Journal | Year: 2013

The pineapple crop has a permanent demand for water, variable and dependent on their stage of development, which may affect the production and fruit quality. This study aimed to evaluate the chemical quality of fruits Smooth cayenne pineapple submitted to different levels and frequency of water replacement in the soil. We used a randomized block design in a 4 × 2 factorial arrangement, consisting of four levels of soil water replenishment (50%, 75%, 100% and 125% of crop evapotranspiration) and two irrigation frequencies (1 and 3 days) with four replications. We evaluated the parameters: juice yield (RS), hydrogen potential (pH), total soluble solids (SST), titratable acidity (ATT), SST/ATT relationship, ascorbic acid (AA). It was observed that the blades and irrigation frequencies did not affect the juice yield (RS) and ascorbic acid (AA), the increase of the blades irrigation influenced positively the quality of the fruit as it increases the values of total soluble solids (SST) decreases the acidity (ATT), raises the relationship SST/ATT and hydrogen potential (pH).

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