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Mandate also includes collaboration with local hospital for innovative Surgical and Anti-Aging procedures EastGate Biotech Corp. (OTC PINK: ETBI), an emerging pharmaceutical company that develops innovative pharmaceutical products and produces and distributes innovative and healthy nutraceuticals based on natural therapies has announced that it has engaged the services of an agent affiliated with the Philippines pharmaceutical industry to seek out suitable joint venture partners and suppliers in the Philippines. The agent, Roger Munoz, a principal of i-Power Philippines, a subsidiary of the ICube Group (www.icube.ph) a large holding group mostly for Nippon SME business in the Philippines,  will work together with the company’s own Global Business Development team to act in EastGate’s interests in identifying local partners for the purposes of clinical testing, registration and marketing of the company’s diabetes-cardiovascular related products including its OTC products and the pharmaceutical product pipeline being developed by EastGate (www.EastGateBiotech.com). According to the World Health Organization, the Philippines is considered a diabetes hotspot.  Presently, 1 out of every 5 Filipinos has diabetes representing 20% of the population.  It is predicted that the Philippines will be part of the top 10 countries affected by diabetes due to the accelerated rate of its citizens developing the disease. The agent, also has a mandate within his own personal capacity to establish collaborations with local hospitals looking to introduce innovative anti-aging treatments and surgical procedures to be provided by EastGate’s wholly-owned subsidiary, OMNI Surgery + Anti-Aging Center (www.OmniSurgery.ca). The agent is already collaborating with a local Neurologist specialist for the purpose of attracting innovation to the Philippines. “We are excited about establishing Joint Venture partnerships in this emerging and growing Philippines market,” states Anna Gluskin, EastGate’s CEO.  “This effort will complement our ongoing business development activities and inroads in other densely-populated diabetes countries in the SEA region. From our early discussions that have been initiated in the Philippines and due to the growing concern for disease management we anticipate that we will be able to enter into productive and viable partnerships in the Philippines soon,” concluded Gluskin. EastGate Biotech develops innovative pharmaceutical products and produces and distributes innovative and healthy nutraceuticals that are based on natural therapies and absorbed naturally by the body.  We utilize advanced nanotechnologies to delivery healthy alternatives to conventional pharmaceuticals that all-too-often create dangerous side-effects and unexpected consequences for those trying to attain and maintain healthy lives. Our research and development team are dedicated to providing the best nutraceutical products and pharmaceutical products for your natural comfort, health and well-being.  We invite you to explore the naturally healthy benefits of EastGate Biotech (www.EastGateBiotech.com). OMNI is a fee-for-service, Surgery + Anti-Aging Centre offering plastic, orthopaedic, along with general surgical procedures. Alongside the surgical procedures, the Anti-Aging Centre is equipped with State-of-the-Art technology that work to contour, tone, and remove blemishes in order to reverse the aging process. As a Centre of Excellence in Saskatchewan, OMNI’s board-certified surgeons work to deliver high-quality care mindful of patients’ needs, while helping them achieve the results they want. All statements, other than statements of historical fact, contained or incorporated by reference in this news release constitute "forward-looking information" or "forward-looking statements" within the meaning of certain securities laws, including the provisions for "safe harbour" under the United States Private Securities Litigation Reform Act of 1995 and are based on expectations, estimates and projections as of the date of this news release. The words "anticipates", "plans", "expects", "indicate", "intend", "scheduled", "estimates", "forecasts", "focus", "guidance", "initiative", "model", "methodology", "outlook", "potential", "projected", "pursue", "strategy", "study", "targets", or "believes", or variations of or similar such words and phrases or statements that certain actions, events or results "may", "could", "would", or "should", "might", or "way forward", "will be taken", "will occur" or "will be achieved" and similar expressions identify forward-looking statements. Forward-looking statements are necessarily based upon a number of estimates and assumptions that are inherently subject to significant business, economic and competitive risks, uncertainties and contingencies. The risks, estimates, models and assumptions contained or incorporated by reference in this release, include those identified from time to time in the reports filed by EastGate with the SEC, which should be considered together with any forward-looking statement. EastGate undertakes no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise.


Mandate Also Includes Collaboration with Local Hospital for Innovative Surgical and Anti-Aging Procedures TORONTO, ON / ACCESSWIRE / May 15, 2017 / EastGate Biotech Corp. (OTC PINK: ETBI), an emerging pharmaceutical company that develops innovative pharmaceutical products and produces and distributes innovative and healthy nutraceuticals based on natural therapies has announced that it has engaged the services of an agent affiliated with the Philippines pharmaceutical industry to seek out suitable joint venture partners and suppliers in the Philippines. The agent, Roger Munoz, a principal of i-Power Philippines, a subsidiary of the ICube Group (www.icube.ph) a large holding group mostly for Nippon SME business in the Philippines, will work together with the company's own Global Business Development team to act in EastGate's interests in identifying local partners for the purposes of clinical testing, registration and marketing of the company's diabetes-cardiovascular related products including its OTC products and the pharmaceutical product pipeline being developed by EastGate (www.EastGateBiotech.com). According to the World Health Organization, the Philippines is considered a diabetes hotspot. Presently, 1 out of every 5 Filipinos has diabetes representing 20% of the population. It is predicted that the Philippines will be part of the top 10 countries affected by diabetes due to the accelerated rate of its citizens developing the disease. The agent, also has a mandate within his own personal capacity to establish collaborations with local hospitals looking to introduce innovative anti-aging treatments and surgical procedures to be provided by EastGate's wholly-owned subsidiary, OMNI Surgery + Anti-Aging Center (www.OmniSurgery.ca). The agent is already collaborating with a local Neurologist specialist for the purpose of attracting innovation to the Philippines. "We are excited about establishing Joint Venture partnerships in this emerging and growing Philippines market," states Anna Gluskin, EastGate's CEO. "This effort will complement our ongoing business development activities and inroads in other densely-populated diabetes countries in the SEA region. From our early discussions that have been initiated in the Philippines and due to the growing concern for disease management we anticipate that we will be able to enter into productive and viable partnerships in the Philippines soon," concluded Gluskin. EastGate Biotech develops innovative pharmaceutical products and produces and distributes innovative and healthy nutraceuticals that are based on natural therapies and absorbed naturally by the body. We utilize advanced nanotechnologies to delivery healthy alternatives to conventional pharmaceuticals that all-too-often create dangerous side-effects and unexpected consequences for those trying to attain and maintain healthy lives. Our research and development team are dedicated to providing the best nutraceutical products and pharmaceutical products for your natural comfort, health and well-being. We invite you to explore the naturally healthy benefits of EastGate Biotech (www.EastGateBiotech.com). OMNI is a fee-for-service, Surgery + Anti-Aging Centre offering plastic, orthopaedic, along with general surgical procedures. Alongside the surgical procedures, the Anti-Aging Centre is equipped with State-of-the-Art technology that work to contour, tone, and remove blemishes in order to reverse the aging process. As a Centre of Excellence in Saskatchewan, OMNI's board-certified surgeons work to deliver high-quality care mindful of patients' needs, while helping them achieve the results they want. All statements, other than statements of historical fact, contained or incorporated by reference in this news release constitute "forward-looking information" or "forward-looking statements" within the meaning of certain securities laws, including the provisions for "safe harbour" under the United States Private Securities Litigation Reform Act of 1995 and are based on expectations, estimates and projections as of the date of this news release. The words "anticipates", "plans", "expects", "indicate", "intend", "scheduled", "estimates", "forecasts", "focus", "guidance", "initiative", "model", "methodology", "outlook", "potential", "projected", "pursue", "strategy", "study", "targets", or "believes", or variations of or similar such words and phrases or statements that certain actions, events or results "may", "could", "would", or "should", "might", or "way forward", "will be taken", "will occur" or "will be achieved" and similar expressions identify forward-looking statements. Forward-looking statements are necessarily based upon a number of estimates and assumptions that are inherently subject to significant business, economic and competitive risks, uncertainties and contingencies. The risks, estimates, models and assumptions contained or incorporated by reference in this release, include those identified from time to time in the reports filed by EastGate with the SEC, which should be considered together with any forward-looking statement. EastGate undertakes no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise.


Shinde V.,ENSTA ParisTech | Longatte E.,ENSTA ParisTech | Baj F.,ENSTA ParisTech | Hoarau Y.,ICUBE | Braza M.,CNRS Institute of Fluid Mechanics of Toulouse
Journal of Computational Physics | Year: 2016

Galerkin projection of the Navier-Stokes equations on Proper Orthogonal Decomposition (POD) basis is predominantly used for model reduction in fluid dynamics. The robustness for changing operating conditions, numerical stability in long-term transient behavior and the pressure-term consideration are generally the main concerns of the Galerkin Reduced-Order Models (ROM). In this article, we present a novel procedure to construct an off-reference solution state by using an interpolated POD reduced basis. A linear interpolation of the POD reduced basis is performed by using two reference solution states. The POD basis functions are optimal in capturing the averaged flow energy. The energy dominant POD modes and corresponding base flow are interpolated according to the change in operating parameter. The solution state is readily built without performing the Galerkin projection of the Navier-Stokes equations on the reduced POD space modes as well as the following time-integration of the resulted Ordinary Differential Equations (ODE) to obtain the POD time coefficients. The proposed interpolation based approach is thus immune from the numerical issues associated with a standard POD-Galerkin ROM. In addition, a posteriori error estimate and a stability analysis of the obtained ROM solution are formulated. A detailed case study of the flow past a cylinder at low Reynolds numbers is considered for the demonstration of proposed method. The ROM results show good agreement with the high fidelity numerical flow simulation. © 2015 Elsevier Inc.


Salzenstein F.,ICube | Montgomery P.,ICube | Boudraa A.O.,Ecole Navale
Optics Express | Year: 2014

In this work, a new method for surface extraction in white light scanning interferometry (WLSI) is introduced. The proposed extraction scheme is based on the Teager-Kaiser energy operator and its extended versions. This non-linear class of operators is helpful to extract the local instantaneous envelope and frequency of any narrow band AM-FM signal. Namely, the combination of the envelope and frequency information, allows effective surface extraction by an iterative re-estimation of the phase in association with a new correlation technique, based on a recent TK crossenergy operator. Through the experiments, it is shown that the proposed method produces substantially effective results in term of surface extraction compared to the peak fringe scanning technique, the five step phase shifting algorithm and the continuous wavelet transform based method. In addition, the results obtained show the robustness of the proposed method to noise and to the fluctuations of the carrier frequency. © 2014 Optical Society of America.


Kopp J.-B.,ICube | Schmittbuhl J.,Ecole et Observatoire des science de la Terre | Lin J.,ICube | Fond C.,ICube
13th International Conference on Fracture 2013, ICF 2013 | Year: 2013

For rapid crack propagations, two kinds of material behavior have been observed. Typically, most materials show an increase of the fracture energy with the crack tip velocity. However, there do exist a few materials for which the fracture energy tends to decrease with the velocity [1, 2]. They are viscoplastic blend materials like polymers such as rubber toughened polymethylmethacrylate (RT-PMMA). For these materials, crack tips are seen to propagate at the same velocity whatever the loading rate is (or strain energy release rate). This critical velocity has been shown to be the crack branching velocity, at least at a macroscopic scale. Our study shows that the classical approach which considers that the amount of created surface during the propagation can be approximated as the sample thickness multiplied by the crack length is not appropriate. Indeed, this study shows that the exact fracture surface roughness has to be included in the amount of created surface in order to establish an intrinsic material fracture energy GID. As the fracture surface roughness depends on the scale at which the sample is observed, a self-affine model widely used for fracture surfaces is introduced [3, 4]. This statistical geometrical model of the fracture surface with two parameters, a Hurst exponent and a topothesy is shown to be effective and provides a better estimate of the intrinsic surface fracture energy. Copyright © (2013) by International Conference on Fracture.


Rubbert L.,Ecole Polytechnique Federale de Lausanne | Caro S.,École Centrale Nantes | Gangloff J.,University of Strasbourg | Renaud P.,ICube
Journal of Mechanical Design, Transactions of the ASME | Year: 2014

The rigid-body replacement method is often used when designing a compliant mechanism. The stiffness of the compliant mechanism, one of its main properties, is then highly dependent on the initial choice of a rigid-body architecture. In this paper, we propose to enhance the efficiency of the synthesis method by focusing on the architecture selection. This selection is done by considering the required mobilities and parallel manipulators in singularity to achieve them. Kinematic singularities of parallel structures are indeed advantageously used to propose compliant mechanisms with interesting stiffness properties. The approach is first illustrated by an example, the design of a one degree of freedom compliant architecture. Then, the method is used to design a medical device where a compliant mechanism with three degrees of freedom is needed. The interest of the approach is outlined after application of the method. Copyright © 2014 by ASME.


Mamoghli S.,LGeCo | Goepp V.,Icube | Botta-Genoulaz V.,INSA Lyon
Enterprise Information Systems | Year: 2015

Enterprise Resource Planning (ERP) systems offer standard functionalities that have to be configured and customised by a specific company depending on its own requirements. A consistent alignment is therefore an essential success factor of ERP projects. To manage this alignment, an ‘Operational Model Based’ method is proposed. It is based on the design and the matching of models, and conforms to the modelling views and constructs of the ISO 19439 and 19440 enterprise-modelling standards. It is characterised by: (1) a predefined design and matching order of the models; (2) the formalisation, in terms of modelling constructs, of alignment and misalignment situations; and (3) their association with a set of decisions in order to mitigate the misalignment risk. Thus, a comprehensive understanding of the alignment management during ERP projects is given. Unlike existing methods, this one includes decisions related to the organisational changes an ERP system can induce, as well as criteria on which the best decision can be based. In this way, it provides effective support and guidance to companies implementing ERP systems, as the alignment process is detailed and structured. The method is applied on the ERP project of a Small and Medium Enterprise, showing that it can be used even in contexts where the ERP project expertise level is low. © 2015 Taylor & Francis


Goepp V.,ICube | Petit M.,University of Namur
ICEIS 2013 - Proceedings of the 15th International Conference on Enterprise Information Systems | Year: 2013

The Strategic Alignment Model (SAM) remains one of the most relevant and cited models aiming at helping managers to achieve business/IT (Information Technology) alignment. Several alternative approaches extend or improve this model. A notable stream of research suggests applying Enterprise Architecture principles complementarily or independently to the SAM. We analyze these proposals and argue that they are sometimes fuzzy and hard to compare because they all use a specific structure or vocabulary making the objectivation of their strengths and weaknesses difficult. Some common vocabulary and concepts such as those of the ISO 15704 standard on Enterprise Reference Architectures and Methodologies are needed to make their comparison rigorous. We report on our ongoing research, using this standard to analyse the SAM.


Boisselier D.,IREPA LASER | Sankare S.,IREPA LASER | Engel T.,ICube
Physics Procedia | Year: 2014

The implementation of the continuous 5-axis configuration can extend the limits of the Laser Direct Metal Deposition (LDMD) processes, especially when the complexity of the parts to be built is growing. In order to follow the profile of a part, we use the orientation of its growth axis. Although 5-axis machining is well known nowadays, LDMD processes require a specific optimization that depends on many parameters. Unlike conventional machining, it has to be noted that the speed variation tool tip affects the stability of deposition. Thus, we have to smooth trajectories in order to provide fluid movements and also to ensure the stability of deposition. This article describes the method and results in the optimization of trajectories to build metallic parts with freeform. Optical sensors have been implemented in the focusing unit in order to follow the variations of the laser-powder-substrate interaction and also to detect the process instabilities. Thanks to the right use of a new and large 5 axis machine and specific setting trajectories, manufacturing parts in 5-axis, with no concession on the construction rate has been possible. © 2014 The Authors. Published by Elsevier B.V.


Petit M.,University of Namur | Goepp V.,ICube
Proceedings - CIE 45: 2015 International Conference on Computers and Industrial Engineering | Year: 2015

Business-IT alignment (BITA) is considered as a crucial challenge faced by enterprises. Several Enterprise-Architecture based solutions (that we call Enterprise Architecture Frameworks - EAFs for BITA) have been proposed in order to help to address this problem. However, currently, there is no systematic evaluation of EAFs to check if they are appropriate for BITA. In this paper, we propose a framework to help the evaluation of EAFs for BITA. The framework contains requirements coming from the ISO 15704 standard and some that we derive from the well-known Strategic Alignment Model of Henderson and Venkatraman. We then apply this evaluation framework to the de-facto standard EAF Archimate® proposed by the Open Group. The analysis allows us to identify a potential extension of Archimate® to make it more appropriate in a BITA context.

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