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Tomiyama N.,Seijoh University | Nakamura Y.,Niigata Hand Surgery Foundation | Mori Y.,Ichinomiyanishi Hospital | Hasegawa R.,Chubu University
Asian Journal of Gerontology and Geriatrics

Purpose. This study compared the effects of lower-extremity resistance exercise combined with either step or static balance exercise on strength and balance in older women. Methods. 27 community-dwelling older women completed a 10-week lower-extremity exercise programme combining resistance exercise with either a step (n=11) or static (n=16) balance exercise. Lower-extremity strength was evaluated using the 30-second chair stand test. Balance was assessed using the one leg stance test, multi-directional reach test, timed up and go test, and four square step test. Results. Respectively for the step and static exercise groups, the 30-second chair stand test for lower-extremity strength improved 36% and 24%, whereas the timed up and go test for balance improved 4% and 8% (with no interaction effect), and the four square step test for balance improved 21% and 1% (with interaction effect). Conclusion. A 10-week combined lower-extremity resistance and balance exercise programme may improve strength in older women, but improvement in balance varies depending on the balance exercise. The risk of fall may be reduced by a combination of resistance and balance exercises. © 2015, Hong Kong Academy of Medicine Press. All rights reserved. Source

Fushimi Y.,Ichinomiyanishi Hospital | Fushimi Y.,Kyoto University | Okada T.,Kyoto University | Yamamoto A.,Kyoto University | And 3 more authors.
Journal of Magnetic Resonance Imaging

Purpose: To investigate the relationship between peripheral pulse wave (PPW)-gating and the carotid systolic pulse wave in a large clinical patient cohort, and to establish a process for correct estimation of delay time from PPW-gating to foot (ie, beginning) or peak times of carotid systolic pulse waves. Materials and Methods: Subjects comprised 209 patients scanned using 3T magnetic resonance imaging (MRI) for PPW-gated phase contrast images at the common carotid artery. Stepwise multiple regression analysis was conducted for the relationship between foot or peak times and the following factors after excluding correlated factors with coefficients â¥0.5: pulse rate (PR); systolic blood pressure; diastolic blood pressure; height; body weight; body mass index; Brinkman index; diabetes mellitus; hypertension; and hyperlipidemia. Results: PR showed significant correlation with foot (r = -0.86, P < 0.001) and peak (r = -0.87, P < 0.001) times. The following equations were derived: foot time (msec) = -8.55 × PR + 993.1 and peak time (msec) = -9.21 × PR + 1142.3. No other factors showed significant correlations. Conclusion: PR was the only factor showing significant relationships to foot and peak times of carotid artery flow. The derived equations will facilitate various kinds of noncontrast MR acquisition with simple PPW-gating. Copyright © 2012 Wiley Periodicals, Inc. Source

Sano R.,Chubu Rosai Hospital | Ando A.,Chubu Rosai Hospital | Masaki M.,Ichinomiyanishi Hospital
Practica Oto-Rhino-Laryngologica

During the period from January 2003 to September 2013, 45 patients (44 males and 1 female, mean age 65 years) were diagnosed as having laryngeal carcinoma at Chubu Rosai hospital. We reviewed the clinical charts of these patients and investigated the treatment outcome and prognostic factor of laryngeal carcinoma. The clinical stage at initial presentation was stage I in 23 patients, stage II in 10 patients, stage III in 6 patients, and stage IV in 6 patients. As initial treatments, operation, radiotherapy (RT), chemoradiotherapy and chemotherapy were done for 7, 28, 9 and 1 patients, respectively. Five-year overall survival rates (OS) and disease-specific survival rates (DSS) for all laryngeal carcinoma patients were 65.4% and 79.0%, respectively. OS and DSS for 34 patients with glottic carcinoma were 71.4% and 84.7%, respectively. OS and DSS for 11 patients with supraglottic carcinoma were 40.0% and 53.3%, respectively. Both the OS and DSS for the glottic carcinoma were significantly higher than those for the supraglottic carcinoma (P=0.011, 0.017). The OS rates for all laryngeal carcinoma patients with stage I, II, III and IV were 92.3%, 40.0%, 33.3% and 40.0%, respectively. The ratio of laryngeal preservation was 71%. Twelve patients died due to laryngeal carcinoma in 6 patients, second primary carcinomas in 3 patients, and other causes in 3 patients. The OS for the patients with stages II and III were poor. Three patients with stage II died of other causes. Two patients with stage III, one of whom rejected surgery, and the other of whom had inoperable general condition, died of laryngeal carcinoma. Therefore the treatment for laryngeal carcinoma was possibly proper. All five patients with normal cord mobility with T2 glottic carcinoma who underwent RT are currently alive with no recurrence. RT may therefore be effective for T2 glottic carcinoma with normal cord mobility. Source

Fushimi Y.,Ichinomiyanishi Hospital | Miyasaki A.,Ichinomiyanishi Hospital | Taki H.,Ichinomiyanishi Hospital | Aoyama K.,Ichinomiyanishi Hospital | And 3 more authors.
Japanese Journal of Radiology

Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle has been recognized as a new type of glioneuronal tumor. RGNTs are typically located in the infratentorial midline with involvement of the fourth ventricle. They occasionally involve the aqueduct and/or vermis. RGNTs of unusual anatomical sites or those with unusual findings have been reported. The present case reports describe RGNT of the fourth ventricle with bilateral olivary degeneration. It is important to accumulate imaging findings and biological behaviors of RGNTs given the limited number of cases. © 2011 Japan Radiological Society. Source

Tanaka N.,Ichinomiyanishi Hospital | Ishihara H.,Ichinomiyanishi Hospital | Ohno H.,Ichinomiyanishi Hospital
Thrombosis Journal

Warfarin, dabigatran, and apixaban are used for preventing ischemic stroke due to non-valvular atrial fibrillation (NVAF). However, it is often challenging to select the appropriate anticoagulant. We present the case of a 70-year-old male patient with persistent NVAF who developed pulmonary thromboembolism (PTE), deep vein thrombosis (DVT), and left atrial thrombus during anticoagulant therapy with warfarin. Intravenous recombinant tissue plasminogen activator was administered during his acute PTE. Heparin and apixaban were administered over 28days; heparin was discontinued after the DVT resolved, while apixaban was administered to prevent ischemic stroke. Two days after heparin was discontinued, the patient experienced an ischemic stroke. Dabigatran was administered for secondary ischemic stroke prevention. Soluble fibrin (SF) levels remained elevated during treatment with heparin and apixaban and returned to normal after apixaban was replaced with dabigatran. Monitoring of SF may be useful as an index for selection of anticoagulants. © 2015 Kawakami et al. Source

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