Bucharest, Romania
Bucharest, Romania

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Begea M.,ICA Research and Development | Vladescu M.,ICA Research and Development
Romanian Biotechnological Letters | Year: 2010

Liquid biofuels are mainly bioethanol, which is produced by fermentation of sugars or starches derived from agricultural selected resources and biodiesel, produced by transesterification of vegetable oils. Despite the large amount of studies performed on bioethanol production, the theme continues to be of interest through the new yeast strains with increased performance in fermentation. In this study, 45 new yeast strains were isolated from fruits and their juices in the air and on special media. Their identification at species level was performed by classical methods. During the experiments seven strains of Sccharomyces cerevisiae were selected and tested both at laboratory and pilot level for their performances. Among these strains, two of them proved to be thermotolerant and reacted positively by moderate development on tested media after a longer period of time (3 to 4 days). The tests conducted in pilot station point out that S.cerevisiae F7 strain produced the largest quantity of alcohol in the fermented meal. Based to their ability to produce ethanol from corn meal, this strain could be used at industrial level for fermentation of various raw materials in order to obtain an increased production of bioethanol. © 2010 University of Bucharest.


Popa O.M.,University of Bucharest | Bojinca M.,University of Bucharest | Bojinca V.,University of Bucharest | Dutescu M.I.,Prof Dr C T Nicolau National Institute Of Blood Transfusion | And 5 more authors.
International Journal of Molecular Sciences | Year: 2011

Tumor necrosis factor alpha (TNF-alpha) is an important pro-inflammatory cytokine implicated in the pathogenesis of psoriatic arthritis. We have performed a case-control association study of three TNF-alpha gene polymorphisms in a group of Romanian psoriatic arthritis patients versus ethnically matched controls. A second group of patients with undifferentiated spondyloarthritis was used in order to look for similarities in the genetic background of the two rheumatic disorders. The -857C/T polymorphism was associated with susceptibility to psoriatic arthritis in our population at the individual level (p = 0.03, OR 1.65, 95% CI 1.05-2.57) and in combined haplotypes with the -238G/A and -308G/A SNPs. Regarding the investigated polymorphisms and derived haplotypes, no potential association was found with the susceptibility to undifferentiated spondyloarthritis in Romanian patients. © 2011 by the authors; licensee MDPI, Basel, Switzerland.


Stoicescu C.,ICA Research and Development | Begea M.,ICA Research and Development | Vladescu M.,ICA Research and Development | Baldea G.,ICA Research and Development | And 2 more authors.
Romanian Agricultural Research | Year: 2011

Biosynthesis of single cell biomass on an industrial level is closely related to biomass multiplication process, namely to the fermentation stage. This requires solving major technological problems, including those related to the choice of optimal conditions leading to higher rates and yields in biomass and to nutrient medium composition optimization. For the fermentation of different raw materials, specific yeast that grows fast, has high yields in biomass, is accommodated to the specific conditions of technological process and is more resistant to infections is required. Despite the large amount of studies performed on biomass production, the theme continues to be of interest due to the new yeast strains with increased performance in fermentation. In this study, 52 new yeast strains were isolated from fruits and their juices and from special media. Their identification at species level was performed by classical methods. After the preliminary experiments, seven strains of Saccharomyces cerevisiae were selected and tested both at laboratory and pilot scale for their performances. Based to their ability to ferment the molasses, these strains could be used at industrial level in order to obtain an increased production of single cell biomass. The tests conducted in pilot station point out that S. cerevisiae DFP strain produced the highest quantity of biomass in the fermented medium.


Serbancea F.,ICA Research and Development | Casulschi T.,ICA Research and Development
Quality - Access to Success | Year: 2011

In recent decades food chain has been complicated by the exponential development of processing methods driven by computerization and automation of processing technologies, equipment modernization and diversification of food. In this context a set of rules is needed to maintain an acceptable safety standard in the food sector. The implementation and operation of quality system in the food industry require large amounts human and financial resources. Operating expenses can be reduced by using an integrated monitoring system, operating on a software system.


Casulschi T.,ICA Research and Development | Serbancea F.,ICA Research and Development
Quality - Access to Success | Year: 2011

Millions of analytical measurements are made every day in thousands of laboratories around the world. Virtually every aspect of society is supported in some way by analytical measurement. The cost of carrying out these measurements is high and additional costs arise from decisions made on the basis of the results. Clearly it is important to determine the correct result and be able to show that it is correct. The aim of this work is to provide some good practice for quality assurance in a laboratory of food analysis. The paper covers both physical-chemical or microbiological analysis carried out on a food control laboratory, including particularities of food products.

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