Ibn Zohr Hospital

Marrakesh, Morocco

Ibn Zohr Hospital

Marrakesh, Morocco

Time filter

Source Type

Elharti E.,National Institute of Hygiene | Oumzil H.,National Institute of Hygiene | Amine M.,Laboratory of Epidemiology | Tassi N.,University Hospital of Marrakech | And 2 more authors.
African Health Sciences | Year: 2010

Objective: To evaluate the clinical and the immune status of newly HIV diagnosed patients, in Marrakech city and its neighboring area, in Morocco. Methods: We performed a retrospective study on 235 patients who have been previously confirmed for HIV infection, and underwent a CD4 T cells using flow cytometry (FacsCount, Becton Dickinson®). Results: The mean age of patients was 34,3 ± 8,4 years (range: 14-55), with a male predominance (sex-ratio M/F=1.4). On basis of clinical data of the patients, 62% (n=146) of them were categorized as "category C", 18.4% (n=43) as "category B", and 19.6% (n=46) as "category A" according to CDC (Center for Disease Control) HIV classification. Among all of them, 60.4% (n=142) had less than 200 CD4T cells, 26% (n=61) had between 200 and 499 CD4T cells, and only 13.6% (n=32) showed a number of CD4T cells less or equal to 500/mm 3. Conclusion: The results of this study reflect a significant delay in the diagnosis of HIV infected patients. Therefore, this delay may compromise timely management of HIV infected individuals and enhances propagation of the epidemic in our country. These data confirm the need for intensifying prevention efforts among high-risk population. Moreover, continuing education in HIV/AIDS among healthcare providers should be reinforced.


Abdel-Hamid N.,Kafr El Sheikh University | Al Jubori T.,Al Mansur Medical Technique Institute | Farhan A.,Al Mansur Medical Technique Institute | Mahrous M.,Minia University | And 3 more authors.
Current Diabetes Reviews | Year: 2013

It has been known that chronic liver treatments interfere with blood glucose metabolism. It was recognized that diabetes mellitus among chronic hepatitis C was greater in other types of chronic liver diseases. Hepatitis C directly promotes insulin resistance through the proteosomal degradation of insulin resistance substrate. It suppressed hepatocyte glucose uptake through down-regulation of surface expression of glucose transporter. Long-term exposure to cytokine over expression seems to be cytotoxic to both beta cells of the pancreas and to hepatocytes. Elevated tumor necrosis factor-a, or its neutralization, increased insulin sensitivity. Interferon-a may also elevate the serum level of interleukin-1 which is cytotoxic to pancreatic islet cells. Both Diabetes mellitus and resistance to interferon-a therapy are abnormally mediated by over-expression of suppressor of cytokine signaling-1 in hepatocytes of chronic hepatitis C patients. Conclusion: These data suggest that interferon-a therapy should be administered with caution in patients showing any predisposition to Diabetes mellitus. Anti inflammatory therapy is critically recommended as a protector against disease development due to cytokine mediated Diabetes mellitus during hepatitis C therapy, since inflammation seems to be a main candidate to interferon suspected diabetogenesis. © 2013 Bentham Science Publishers.


Gouri A.,Ibn Zohr Hospital | Dekaken A.,El Okbi Hospital | Bentorki A.A.,Ibn Zohr Hospital | Touaref A.,Ibn Zohr Hospital | And 2 more authors.
Clinical Laboratory | Year: 2014

Background: Elevated serum uric acid (SUA) was usually associated with an increased risk of cardiovascular events and mortality in the general population. However, there are few reports concerning the clinical impact and the pathogenic role of uric acid (UA) in hemodialysis (HD) patients. The aim of the study was to investigate the relationship between SUA and various cardiovascular (CV) risk factors in HD patients. Methods: This retrospective, observational cohort study includes 45 HD patients with a mean age of 51.26 ± 15.21 years. The differences of the CV risk factors between the patients according to their SUA levels were investigated. Results: Age, cardiovascular diseases (CVD), increased creatinine, fasting blood glucose (FBG), corrected calcium (cCa), phosphate (P), cCa x P product, and LDL cholesterol levels were associated with lower SUA levels, whereas a higher SUA level was associated with diabetes mellitus (DM), hypertension, and increased triglycerides level (p < 0.01). In multiple regression analysis, history of diabetes (β = 0.360, p < 0.05), reduced corrected serum calcium (cCa) (β = -1.456, p < 0.01), and phosphate (P) levels (β = -1.752, p < 0.01) were predictive of an increased SUA concentration. Conclusions: Despite what has been demonstrated in the general population and DM patients, a lower SUA level in HD patients was associated with higher cardiovascular risk factors and high co-morbidity burden. Moreover, higher SUA concentrations may be cardioprotective in dialysis patients.


Dekaken A.,El Okbi Hospital | Gouri A.,IBN Zohr Hospital | Bentorki A.A.,El Okbi Hospital | Yakhlef A.,IBN Zohr Hospital
Annales de Biologie Clinique | Year: 2014

Primary hyperparathyroidism is a common endocrine disorder, asymptomatic and diagnosed through a fortuitous hypercalcemia. Browntumors are exceptional but severe hyperparathyroidism bone complications.We report in this paper an original observation of hyperparathyroidism due to a parathyroid adenoma presenting as a brown tumor. A 28 year-old girl admitted for a bone tumor of the knee, the blood test shows hypercalcemia with hyperparathyroidism, bone biopsy revealed giant cell lesions characteristic of brown tumors.


Gouri A.,IBN ZOHR Hospital | Dekaken A.,EL OKBI Hospital | Bentorki A.A.,IBN ZOHR Hospital | Touaref A.,IBN ZOHR Hospital | And 3 more authors.
Pakistan Journal of Biological Sciences | Year: 2013

Elevated Serum Uric Acid (SUA) was usually associated with an increased risk of cardiovascular events and mortality in general population. However, there are few reports concerning the clinical impact and the pathogenic role of Uric Acid (UA) in Hemodialysis (HD) patients. The aim of the study was to investigate the relationship between SUA and various Cardiovascular (CV) risk factors in HD patients. This retrospective; observational cohort study includes 45 HD patients with a mean age of 51.26±15.21 years. The differences of the CV risk factors between the patients according to their SUA levels were investigated. Age, Cardiovascular Diseases (CVD), increased creatinine, Fasting Blood Glucose (FBG), Corrected Calcium (cCa), Phosphate (P), cCa x P product and LDL cholesterol levels were associated with lower SUA levels, whereas higher SUA level was associated with Diabetes Mellitus (DM), hypertension and increased triglycerides level (p<0.01). In multiple regression analysis, history of diabetes (β = 0.360, p<0.05), reduced corrected serum calcium (cCa) (β = -1.456, p<0.01) and Phosphate (P) levels (β = -1.752, p<0.01) were predictive of an increased SUA concentration. Despite from what has been demonstrated in the general population and DM patients, a lower SUA level in HD patients was associated with higher cardiovascular risk factors and high co-morbidity burden. Moreover, higher SUA concentrations may be cardioprotective in dialysis patients. © 2013 Asian Network for Scientific Information.


Gouri A.,Ibn Zohr hospital | Dekaken A.,El Okbi hospital | Yakhlef A.,Ibn Zohr hospital | Bentorki A.A.,Ibn Zohr hospital | Kouicem N.,Ibn Zohr hospital
Immuno-Analyse et Biologie Specialisee | Year: 2012

Dyslipidemia is often observed in hemodialysis patients (HD), resulting in abnormal concentrations and composition of plasma lipoproteins. Non-high-density-lipoprotein cholesterol (Non HDL-C) has been proposed as a good estimator of the atherogenic potential in general population; however, there are limited data of non-HDL-C in hemodialysis patients. The objective of this study was to assess the prevalence of lipid abnormalities in a cohort of Algerian hemodialysis patients and to test the ability of non-HDL-C to identify non-traditional lipoprotein subclass risk factors in this population. Forty-five hemodialysis patients with a mean age of 51.26 ± 15.21 years participated in this study. The most frequent lipid alteration recorded was decreased HDL-C (75.5%), followed by increased non-HDL-C (73.4%) and hypertriglyceridemia (24.5%). The levels of total cholesterol, LDL-C and the LDL-C/HDL-C ratio were significantly higher and the HDL-C levels were significantly lower in the high non-HDL-C group than those in the low non-HDL-C group. Furthermore, a significant correlation was found between non-HDL-C and LDL-C levels (r=0.84, P<0.001), total cholesterol levels (r=0.75, P<0.001) and atherogenic index (r=0.62, P<0.001) in this population. Our study suggests that non-HDL-C may be the best lipoprotein parameter for managing dyslipidemia and evaluating cardiovascular disease risk among HD patients. © 2012 Elsevier Masson SAS.


PubMed | IBN ZOHR Hospital and EL OKBI Hospital
Type: Journal Article | Journal: Pakistan journal of biological sciences : PJBS | Year: 2014

Elevated Serum Uric Acid (SUA) was usually associated with an increased risk of cardiovascular events and mortality in general population. However, there are few reports concerning the clinical impact and the pathogenic role of Uric Acid (UA) in Hemodialysis (HD) patients. The aim of the study was to investigate the relationship between SUA and various Cardiovascular (CV) risk factors in HD patients. This retrospective; observational cohort study includes 45 HD patients with a mean age of 51.26+/-15.21 years. The differences of the CV risk factors between the patients according to their SUA levels were investigated. Age, Cardiovascular Diseases (CVD), increased creatinine, Fasting Blood Glucose (FBG), Corrected Calcium (cCa), Phosphate (P), cCa x P product and LDL cholesterol levels were associated with lower SUA levels, whereas higher SUA level was associated with Diabetes Mellitus (DM), hypertension and increased triglycerides level (p<0.01). In multiple regression analysis, history of diabetes (beta= 0.360, p<0.05), reduced corrected serum calcium (cCa) (beta = -1.456, p<0.01) and Phosphate (P) levels (beta= -1.752, p<0.01) were predictive of an increased SUA concentration. Despite from what has been demonstrated in the general population and DM patients, a lower SUA level in HD patients was associated with higher cardiovascular risk factors and high co-morbidity burden. Moreover, higher SUA concentrations may be cardioprotective in dialysis patients.

Loading Ibn Zohr Hospital collaborators
Loading Ibn Zohr Hospital collaborators