Ibaraki Christian University is a private university in Hitachi, Ibaraki, Japan, established in 1967. The predecessor of the University, Ibaraki Christian College, was founded in 1949.Ibaraki Christian University has liaisons and student-exchange programs with a number of universities outside Japan. These include Oklahoma Christian University, with which McMillan was also involved.The institution has had an international focus from its inception. Wikipedia.
PubMed | Tokyo Gakugei University, Ibaraki Christian University and National Institute of Mental Health
Type: | Journal: Journal of clinical and experimental neuropsychology | Year: 2016
Action monitoring, the process for evaluating the appropriateness of ones own actions, is reported to be atypical in individuals with autism spectrum disorder (ASD).We examined the characteristics of action monitoring in 11 children with ASD and 12 children with typical development (TD), analyzing stimulus-locked and response-locked event-related potential components (i.e., N2; error-related negativity, ERN; and error positivity, Pe) related to execution of a flanker task.We found a smaller N2 amplitude in children with ASD than in those with TD. Children with ASD also had a larger amplitude of ERN for partial error responses (electromyographic activity corresponding to the inappropriate hand side before response execution) than did children with TD. Additionally, the ERN amplitude for the partial error response was correlated with the Autistic Mannerisms of the Social Responsiveness Scale. There were no significant differences in Pe amplitudes between children with ASD and those with TD.The results suggest that action monitoring in children with ASD is significantly different both before and after response execution. We hypothesized that the detail-focused processing style of ASD reduces the demands of action monitoring before response execution; however, autistic mannerisms evoke excessive concern regarding trivial mistakes after response execution.
Matsui Y.,Japan National Traffic Safety and Environment Laboratory |
Hitosugi M.,Dokkyo Medical University |
Takahashi K.,Japan National Traffic Safety and Environment Laboratory |
Doi T.,Ibaraki Christian University
Traffic Injury Prevention | Year: 2013
Objective: To reduce the severity of injuries and the number of pedestrian deaths in traffic accidents, active safety devices providing pedestrian detection are considered effective countermeasures. The features of car-to-pedestrian collisions need to be known in detail to develop such safety devices.Methods: Because information on real-world accidents is limited, this study investigated near-miss situations captured by drive recorders installed in passenger cars. We showed similarities of the contact situation between near-miss incidents and real-world fatal pedestrian accidents in Japan. We analyzed the near-miss incident data via video capturing pedestrians crossing the road in front of forward-moving cars. Using a video frame captured by a drive recorder, the time to collision (TTC) was calculated from the car velocity and the distance between the car and pedestrian at the moment that the pedestrian initially appeared.Results: The average TTC in the cases where pedestrians were not using a pedestrian crossing was shorter than that in the cases where pedestrians were using a pedestrian crossing. The average TTC in the cases where pedestrians emerged from behind obstructions was shorter than that in the cases where drivers had unobstructed views of the pedestrians.Conclusions: We propose that the specifications of the safety device for pedestrian detection and automatic braking should reflect the severe approach situation for a pedestrian and car including the TTC observed for near-miss incidents. © 2013 Copyright Taylor and Francis Group, LLC.
PubMed | Teikyo University, Ibaraki Christian University, National Institute of Mental Health, Tokyo Electron and Hyogo Childrens Sleep and Development Medical Research Center
Type: Journal Article | Journal: Brain & development | Year: 2016
The diagnosis of Developmental Coordination Disorder (DCD) requires a precise assessment of motor skills via a standardized tool such as the Movement Assessment Battery for Children-Second Edition (MABC-2). Although the MABC-2 has been widely used in English-speaking countries, to the best of our knowledge, no studies have examined its applicability to Japanese children. Thus, it has been difficult to diagnose DCD in Japan.As a preliminary investigation preceding its formal standardization in Japan, we examined the applicability of the MABC-2.Participants comprised 132 typically developing Japanese children who completed a test set of the MABC-2 for Age Band 2. We analyzed both internal consistency and factorial validity for our Japanese sample. We also included a comparison between our sample of Japanese children and the normative sample of the MABC-2, as well as an examination of gender differences.Our results indicated acceptable internal consistency and scale homogeneity. High factorial validity, which has not been examined in other populations, was also confirmed for the test set. Moreover, we found differences in component scores between the Japanese and normative children with respect to Manual Dexterity and Balance. We also found that girls obtained superior Manual Dexterity and Balance scores compared with boys.The present findings represent the first step towards the standardization of the MABC-2 in a Japanese population.
PubMed | Ibaraki Christian University and Tsukuba International University
Type: Journal Article | Journal: Anatomical record (Hoboken, N.J. : 2007) | Year: 2016
The purpose of this study was to quantitatively clarify differences in laminar structure and myeloarchitecture of sulcal and gyral regions of the cerebral cortex of ferrets. Histological sections of cerebrum from male and female ferrets at postnatal day 90 were made at the coronal plane, and were immunostained with anti-NeuN or anti-myelin basic protein (MBP). Thickness was estimated in the entire depth or three strata, that is, layer I, outer (layers II-III) and inner (layers IV-VI) strata of the neocortex in representative five sulcal and seven gyral regions. As with the entire cortical depth, outer and inner strata were significantly thinner in the sulcal bottoms than in the gyral crowns, whereas layer I had about twofold greater thickness in the sulcal bottoms. However, thicknesses of the entire cortical depth and each cortical stratum were not statistically different among five sulcal regions or seven gyral regions examined. By MBP immunostaining, myelin fibers ran tangentially through the superficial regions of layer I in gyral crowns. Those fibers were relatively denser in gyri of frontal and temporal regions, and relatively sparse in gyri of parietal and occipital regions, although their density in any gyri was not different between sexes. These results show a differential laminar structure and myeloarchitecture between the sulcal and gyral regions of the ferret cerebral cortex present in both sexes. Myelination of layer I tangential fibers varied among primary gyri and was weaker in phylogenetically higher-order cortical gyri. Anat Rec, 299:1003-1011, 2016. 2016 Wiley Periodicals, Inc.
PubMed | Osaka University, Japan National Institute of Radiological Sciences, Tsukuba International University, Saitama University and Ibaraki Christian University
Type: Journal Article | Journal: Congenital anomalies | Year: 2016
Growth-retarded mouse (grt/grt) is a spontaneous mutant that is known as an animal model for primary congenital hypothyroidism caused by resistance to TSH signaling. The regional pattern of cerebral cortical hypoplasia was characterized in grt/grt mice. Ex vivo computed tomography (CT)-based volumetry was examined in four regions of the cerebral cortex, i.e., prefrontal, frontal, parietal and occipito-temporal regions, which were demarcated by structural landmarks on coronal CT images. A region-specific reduced volume of the parietal cortical region covering most of the somatosensory cortex was noted in grt/grt mice rather than in both heterozygous (grt/+) and wild-type (+/+) mice. We concluded that the cortical hypoplasia in grt/grt was seen in identical cortical regions corresponding to human congenital hypothyroidism.
Matsui Y.,National Traffic Safety and Enviro Laboratory |
Doi T.,Ibaraki Christian University |
Oikawa S.,National Traffic Safety and Enviro Laboratory |
Ando K.,National Traffic Safety and Enviro Laboratory
SAE International Journal of Transportation Safety | Year: 2013
The number of traffic deaths in Japan was 4,612 in 2011. Looking at the road accident fatalities, it revealed that pedestrians accounted for the highest number in 2011 (1,686, 36.6%). To develop safety countermeasures to decrease the severity of injuries and to reduce the number of deaths in traffic accidents, the detailed characteristics of pedestrian injury in vehicle-to-pedestrian crashes are necessary. The purpose of this study is to understand the scenarios of vehicle accidents in which pedestrians suffer fatal injuries. In the present study, we investigated the characteristics of pedestrian injuries in fatal crashes from accident analyses and compared them to head injury severity levels in impact tests against a road pavement and vehicle contact surfaces. In the accident analyses, we investigated the main body regions injured, that is, the most serious extent of injuries over the whole body of pedestrians by using macro vehicle-pedestrian accident data from database of the Institute for Traffic Accident Research and Data Analysis (ITARDA) of Japan. In comparing the differences in injury frequencies for various body regions between 1999 and 2009, it is noted that the frequencies of pedestrian fatalities due to head injuries were significantly reduced. The result indicated that even though head injuries were the most frequent cause of pedestrian fatalities in traffic accidents, the introduction of pedestrian head protection regulation in Japan in 2005 could be considered effective in reducing fatal head injuries. On the other hand, the frequencies of pedestrian fatalities due to hip injuries increased significantly in sedans, light passenger cars, and light cargo vans. Using the macro accident data in 2009, we investigated the frequency of pedestrian fatalities by gender, age group, vehicle travel speed, and fatal head injuries due to vehicle impacts or road pavement impacts. The results also indicated that the frequencies of female pedestrian fatalities due to hip injuries were significantly higher than those of males. Additionally, the results showed that the frequency of pedestrian fatalities due to hip injuries for the age group of over 65 years was significantly higher than that of the industrial age group (aged 13-59). Focusing on the frequency of pedestrian fatalities due to hip injuries in all age groups, vehicle travel speed appeared likely not to be an extremely important factor in increasing fatal hip injuries. In examining the differences in the frequency of fatal head injuries due to contacts with vehicles or road pavements, it is noted that injury frequency in crashes involving vehicles travelling at high speeds were significantly higher than those at lower speeds for pedestrians over 60 years of age. Focusing on head injury severity levels in impact tests against a road and vehicle surfaces using an adult pedestrian headform impactor, the impacts against a road pavement (HIC 6525) was considered to be more severe than those against vehicle front components with high stiffness (HIC from 2600 to 4032). Copyright © 2013 SAE International.
Sengoku Y.,University of Tsukuba |
Nakamura K.,Ibaraki Christian University |
Ogata H.,University of Tsukuba |
Nabekura Y.,University of Tsukuba |
And 2 more authors.
International Journal of Sports Physiology and Performance | Year: 2015
The current case study intended to measure blood glucose fluctuation in 2 marathon runners during a 100-km race using a continuous glucose-monitoring system (CGMS) and investigate the relationship between glucose profile and change in running speed. Two experienced ultramarathon runners participated in this study. A CGMS glucose sensor was inserted into the subcutaneous abdominal tissue at 35 h before the 100-km race, and the glucose profile was monitored continuously until the end of the race. Race pace and energy intake during the race were recorded. Participants finished the race in 6h:51min:17s (runner A) and 8h:56min:04s (runner B), and the race-pace decrement ratios were 17.6% for runner A and 27.2% for runner B. The average relative intensity throughout the 100-km race was 89.9% ± 5.8% lactate threshold (LT) in runner A and 78.4% ± 8.6% LT in runner B. The total amount of carbohydrate intake during the race was 249 g and 366 g in runners A and B, respectively. Despite lower carbohydrate intake, runner A maintained a normal glucose level throughout the race, while runner B rapidly decreased blood glucose and became hypoglycemic after the 80-km point. These results suggest that elite ultramarathon runners may have the ability to prevent a large decrement in blood glucose level regardless of the amount of energy intake during the race to maintain higher relative running intensity. © 2015 Human Kinetics, Inc.
Matsuzaki H.,Tokyo University of Agriculture |
Katsumata S.-I.,Tokyo University of Agriculture |
Kajita Y.,Ibaraki Christian University |
Miwa M.,Tokyo University of Agriculture
Magnesium Research | Year: 2013
A magnesium (Mg) deficiency induces changes in calcium (Ca) and phosphorus (P) metabolism; however, the mechanisms responsible for these effects remain unclear. Since 1,25-dihydroxyvitamin D3 and type II sodium-phosphate (Na/Pi) cotransporters are essential regulators of Ca and P metabolism, this study examined the effects of Mg deficiency on the mRNA expression of vitamin D metabolizing enzymes (25-hydroxyvitamin D-1α-hydroxylase (1α(OH)ase) and 25-hydroxyvitamin D- 24-hydroxylase (24(OH)ase)), and Na/Pi cotransporters (type IIa and IIc) in the rat kidney. Rats were divided into two groups and fed a control diet (Mg concentration: 0.05%) or a Mg-deficient diet (Mg concentration: Mg-free) for 21 days. 1α(OH)ase mRNA levels were significantly decreased in rats fed the Mg-deficient diet, while 24(OH)ase mRNA levels were significantly increased, compared to rats fed the control diet. Type IIa and IIc Na/Pi cotransportermRNA levels in rats fed the Mg-deficient diet were significantly decreased compared to rats fed the control diet. These results suggest that Mg deficiency induces downregulation of 1α(OH)ase and type IIa and IIc Na/Pi cotransporters, and upregulation of 24(OH)ase in the kidney.
Matsuzaki H.,Tokyo University of Agriculture |
Kajita Y.,Ibaraki Christian University |
Miwa M.,Tokyo University of Agriculture
Magnesium Research | Year: 2013
A magnesium (Mg)-deficient diet results in decreased serum phosphorus (P) levels and increased urinary P excretion; however, the mechanisms responsible for these effects are unclear. Fibroblast growth factor-23 (FGF-23) is a potent regulator of P homeostasis. To determine the mechanisms responsible for the change in serum levels and urinary excretion of P with Mg deficiency, the present study examined the effects of Mg deficiency on serum FGF-23 levels. Male rats were randomized by weight into two groups and fed a control diet (Mg concentration: 0.05%) or a Mg-deficient diet (Mg concentration: Mg-free) for 21 days. Serum P levels in rats fed the Mg-deficient diet were significantly lower than in rats fed the control diet. Furthermore, urinary P excretion was significantly higher in rats fed the Mg-deficient diet compared to rats fed the control diet. Conversely, the tubular reabsorption rate of P was significantly lower in rats fed the Mg-deficient diet than in the controls. Serum FGF-23 levels in rats fed the Mg-deficient diet were significantly higher than those in animals fed the control diet. The results from the present study indicate that 1) Mg deficiency increases serum FGF-23 levels; and 2) Mg deficiency causes increased urinary P excretion via inhibition of renal P reabsorption, resulting in a lowering of serum P levels. Moreover, we suggest that the high serum FGF-23 levels induced by Mg deficiency contribute to the decrease in renal P reabsorption.
PubMed | Tokyo University of Agriculture and Ibaraki Christian University
Type: Journal Article | Journal: Magnesium research | Year: 2016
Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphorus (P) and vitamin D metabolism. Long-term dietary magnesium (Mg) deficiency increases circulating levels of FGF23, whereas the effects of short-term dietary Mg deficiency are unclear. Thus, the present study investigated whether short-term dietary Mg deficiency affects circulating levels of FGF23. We also assessed changes in renal mRNA expression of vitamin D metabolizing enzymes and type II sodium-phosphate (Na/Pi) cotransporters, since these are regulated by FGF23. Rats were fed a control diet (control group) or an Mg-deficient diet (Mg-deficient group) for 2, 4 or 7 days. Serum Mg levels were significantly lower in the Mg-deficient group than in the control group at all time points. Serum FGF23 levels were significantly higher in the Mg-deficient group than in the control group at day 7. The 25-hydroxyvitamin D-24-hydroxylase (24(OH)ase) mRNA levels were significantly higher in the Mg-deficient group than in the control group at day 7 . No significant differences in types IIa and IIc Na/Pi cotransporter mRNA levels were observed between the control and Mg-deficient groups. These results suggest that dietary Mg deficiency causes a rapid increase in circulating levels of FGF23 and renal 24(OH)ase mRNA levels.