Shanghai, China

Hutchison MediPharma

www.hmplglobal.com
Shanghai, China

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Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.


Crystalline forms of compound 6-(6,7-dimethoxyquinazolin-4-yloxy)-N,2- dimethylbenzofuran-3-carboxamide, pharmaceutical compositions and the methods of preparation and the use thereof.


Patent
Hutchison MediPharma | Date: 2017-08-02

This disclosure provides novel imidazopyridazine compounds of formula (I) and pharmaceutical acceptable salt thereof, pharmaceutical compositions containing them, a process for preparing them, and their practical effect in inhibiting PI3K and potential use in treating a disease responsive to inhibition of PI3K, for example, an inflammatory disease, autoimmune disease or cancer.


Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.


Provided are certain triazolopyridines, compositions thereof and their use in the treatment of cancer.


Provided are certain triazolopyrazines, compositions thereof and methods of use therefor.


Patent
Hutchison MediPharma | Date: 2014-03-14

The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R^(1), R^(2), R^(3), R^(4), R^(5), X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.


Patent
Hutchison MediPharma | Date: 2013-03-15

The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R^(1), R^(2), R^(3), R^(4), R^(5), X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.


Patent
Hutchison MediPharma | Date: 2013-03-15

Provided are novel heteroaryl and heterocycle compounds of formula (I-1), (I-2) or (I-3) and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of PI_(3)K and for treating inflammatory and autoimmune disorders diseases and cancer.


Disclosed are novel heteroaryl and heterocycle compounds of formula I-1, I-2 or I-3 and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of PI_(3)K and for treating inflammatory and autoimmune diseases and cancer.

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