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Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.


Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.


Provided are certain triazolopyridines, compositions thereof and their use in the treatment of cancer.


Provided are certain triazolopyrazines, compositions thereof and methods of use therefor.


Patent
Hutchison MediPharma | Date: 2014-03-14

The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R^(1), R^(2), R^(3), R^(4), R^(5), X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.


Patent
Hutchison MediPharma | Date: 2013-03-15

The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R^(1), R^(2), R^(3), R^(4), R^(5), X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.


Patent
Hutchison MediPharma | Date: 2013-03-15

Provided are novel heteroaryl and heterocycle compounds of formula (I-1), (I-2) or (I-3) and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of PI_(3)K and for treating inflammatory and autoimmune disorders diseases and cancer.


Patent
Hutchison MediPharma | Date: 2013-12-06

The present invention relates to pyridopyrazine compounds of formula (I), pharmaceutical compositions thereof and methods of use therefore, wherein R^(1), R^(2), R^(3), L, m, p and W are as defined in the specification.


Disclosed are novel heteroaryl and heterocycle compounds of formula I-1, I-2 or I-3 and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of PI_(3)K and for treating inflammatory and autoimmune diseases and cancer.


Compound of Formula A and pharmaceutically acceptable salts thereof and crystalline Forms I and II of Compound of Formula A! Also, methods for the preparation of such compounds, pharmaceutical compositions comprising such compounds, and methods for their uses.

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