Hubei University of Technology ; simplified Chinese: 湖北工业大学; traditional Chinese: 湖北工業大學; pinyin: Húběi gōngyè dàxué; Specializing in engineering,is founded in 1952, located in Wuhan, Hubei, China. It's a public key multi-discipline university of Hubei Province. Wikipedia.
Hubei University of Technology | Date: 2016-02-19
A method of calculating the potential sliding surface of the progressive failure of slope is provided, which is also abbreviated as a failure angle rotation method. The method performs the search calculation of the potential sliding surface of the slope to determine the potential sliding surface, under the assumption that the geological material failure satisfies the condition of the angle between the maximum shear stress surface and the minimum principal stress axis corresponding to the critical stress state being (45 +/2), and based on the fact that the principal stress directions at different positions are rotated while the slope is applied different external loads and gravity loads. The failure path is varied with the change of the stress during the failure process to perform the solution for the potential sliding surface of the slope based on numerical calculation.
Wang Z.,Hubei Engineering University |
Kang Y.,Hubei University of Technology |
Wang Z.,Hubei University of Technology
Journal of Polymer Engineering | Year: 2017
Crumb rubber (CR), as a final product from end-of-life tires through size reduction process, has proved an appropriate end product for accumulated discard waste tires all around the world. Unlike pre-existing pulverization methods, such as ambient or cryogenic grinding and solid-state shear extrusion, an entire cool pulverization process utilizing ultra-high pressure water jet (UHPWJ) was proposed in this paper. Pulverization experiments under various processing parameters were designed and conducted. The particle size distributions of produced CR were obtained using laser particle analyzer. Microscopic morphologies of CR and rubber fracture surface were observed under scanning electron microscopy. The crosslink density and gel fraction of produced CR were experimentally determined. Influence of four main processing parameters as pump pressure, transverse velocity, standoff distance and impacting angle was discussed in detail, and the most suitable processing parameters were recommended. The results show that the particle size distribution of produced CR with UHPWJ is between 45 μm and 200 μm, and the surface of CR is coarse and porous. High compressive shear effect and erosion are the main mechanisms in UHPWJ pulverization. Besides, the produced CR has already been partly devulcanized after UHPWJ pulverization, and polymer degradation occurred in the meanwhile. © 2017 Walter de Gruyter GmbH, Berlin/Boston.
PubMed | University of Alberta, Texas A&M University, University of Washington, Hubei University of Technology and University of Louisville
Type: | Journal: Gastroenterology research and practice | Year: 2016
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the world, and it comprises a spectrum of hepatic abnormalities from simple hepatic steatosis to steatohepatitis, fibrosis, cirrhosis, and liver cancer. While the pathogenesis of NAFLD remains incompletely understood, a multihit model has been proposed that accommodates causal factors from a variety of sources, including intestinal and adipose proinflammatory stimuli acting on the liver simultaneously. Prior cellular and molecular studies of patient and animal models have characterized several common pathogenic mechanisms of NAFLD, including proinflammation cytokines, lipotoxicity, oxidative stress, and endoplasmic reticulum stress. In recent years, gut microbiota has gained much attention, and dysbiosis is recognized as a crucial factor in NAFLD. Moreover, several genetic variants have been identified through genome-wide association studies, particularly rs738409 (Ile748Met) in PNPLA3 and rs58542926 (Glu167Lys) in TM6SF2, which are critical risk alleles of the disease. Although a high-fat diet and inactive lifestyles are typical risk factors for NAFLD, the interplay between diet, gut microbiota, and genetic background is believed to be more important in the development and progression of NAFLD. This review summarizes the common pathogenic mechanisms, the gut microbiota relevant mechanisms, and the major genetic variants leading to NAFLD and its progression.