Wuhan, China
Wuhan, China

The Hubei University , colloquially known in Chinese as Huda was founded in 1931 and is as a key comprehensive university in Hubei Province, People's Republic of China. The University originated in 1931, starting from what was then Hubei Provincial College of Education. Established with approval from the national government, its first director was Huang Jianzhong. The College moved between locations and changed its name several times during its half-century of development. Since 1984, it has been Hubei University. Wikipedia.


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Zhao Q.,National University of Singapore | Jiang W.,Wuhan University | Jiang W.,Hubei University | Srolovitz D.J.,University of Pennsylvania | Bao W.,National University of Singapore
Acta Materialia | Year: 2017

Experiments, theory and atomistic simulations show that finite triple junction mobility results in non-equilibrium triple junction angles in evolving polycrystalline systems. These angles have been predicted and verified for cases where grain boundary migration is steady-state. Yet, steady-state never occurs during the evolution of polycrystalline microstructures as a result of changing grain size and topological events (e.g., grain face/edge switching - “T1” process, or grain disappearance “T2” or “T3” processes). We examine the non-steady evolution of the triple junction angle in the vicinity of topological events and show that large deviations from equilibrium and/or steady-state angles occur. We analyze $∖tau$ the characteristic relaxation time of triple junction angles τ by consideration of a pair of topological events, beginning from steady-state migration. Using numerical results and theoretical analysis we predict how the triple junction angle varies with time and how τ varies with triple junction mobility. We argue that it is precisely those cases where grain boundaries are moving quickly (e.g., topological process in nanocrystalline materials), that the classical steady-state prediction of the triple junction angle about finite triple junction mobility is inapplicable and may only be applied qualitatively. © 2017 Acta Materialia Inc.


Wang Q.,Hubei University | Zhan H.,Hubei University | Zhan H.,Texas College
Journal of Hydrology | Year: 2017

Flow to a partially penetrating vertical well is made more complex by intra-wellbore losses. These are caused not only by the frictional effect, but also by the kinematic effect, which consists of the accelerational and fluid inflow effects inside a wellbore. Existing models of flow to a partially penetrating vertical well assume either a uniform-flux boundary condition (UFBC) or a uniform-head boundary condition (UHBC) for treating the flow into the wellbore. Neither approach considers intra-wellbore losses. In this study a new general solution, named the mixed-type boundary condition (MTBC) solution, is introduced to include intra-wellbore losses. It is developed from the existing solutions using a hybrid analytical-numerical method. The MTBC solution is capable of modeling various types of aquifer tests (constant-head tests, constant-rate tests, and slug tests) for partially or fully penetrating vertical wells in confined aquifers. Results show that intra-wellbore losses (both frictional and kinematic) can be significant in the early pumping stage. At later pumping times the UHBC solution is adequate because the difference between the MTBC and UHBC solutions becomes negligible. © 2017 Elsevier B.V.


Liu X.,Hubei University | Liu X.,Georgia Institute of Technology | Iocozzia J.,Georgia Institute of Technology | Wang Y.,Hubei University | And 5 more authors.
Energy and Environmental Science | Year: 2017

The controlled synthesis of nanohybrids composed of noble metals (Au, Ag, Pt and Pd, as well as AuAg alloy) and metal oxides (ZnO, TiO2, Cu2O and CeO2) have received considerable attention for applications in photocatalysis, solar cells, drug delivery, surface enhanced Raman spectroscopy and many other important areas. The overall architecture of nanocomposites is one of the most important factors dictating the physical properties of nanohybrids. Noble metals can be coupled to metal oxides to yield diversified nanostructures, including noble metal decorated-metal oxide nanoparticles (NPs), nanoarrays, noble metal/metal oxide core/shell, noble metal/metal oxide yolk/shell and Janus noble metal-metal oxide nanostructures. In this review, we focus on the significant advances in tailored nanostructures of noble metal-metal oxide nanohybrids. The improvement in performance in the representative solar energy conversion applications including photocatalytic degradation of organic pollutants, photocatalytic hydrogen generation, photocatalytic CO2 reduction, dye-sensitized solar cells (DSSCs) and perovskite solar cells (PSCs) are discussed. Finally, we conclude with a perspective on the future direction and prospects of these controllable nanohybrid materials. © The Royal Society of Chemistry 2017.


Qiu Y.W.,CAS South China Sea Institute of Oceanology | Qiu H.L.,Hubei University
IOP Conference Series: Earth and Environmental Science | Year: 2017

Trace metals in mangrove tissues (leaf, branch and root) of two species (Rhizophora stylosa and Sonneratia hainanensis) from Dongzhai Harbor and Sanya Bay of Hainan Island were studied. The total average concentrations of Cu, Pb, Zn, Cd, Cr, Hg and As in the two mamgrove species were 2.4±1.3, 1.1±0.7, 7.8±8.0, 0.03±0.05, 1.4±1.6, 0.03±0.01 and 0.2±0.2 μg g-1 dw, respectively. Metals concentrations among different tissues of mangroves showed different pattern. In general, Zn, Cd and Hg were slightly enriched in leaf, Cu, Pb and As was enriched in root, and Cr were enriched in branch. Metals levels in R. stylosa and S. hainanensis from both Dongzhai Harbor and Sanya Bay were compared, which suggested that different mangrove species have their unique mechanism to bioaccumulate metals and TOC in the mangrove sediment could be one of the important factors for regulating metals in mangrove tissues. The biota-sediment accumulation factors (BSAF) of metals in mangrove tissues were calculated. The distribution of metals concentrations in mangrove tissues against metals levels in sediment demonstrated that mangrove leaves could be employed as a bio-indicator for some metals (Cu, Zn, Cd and Hg) with temporal monitoring. © Published under licence by IOP Publishing Ltd.


Sun J.,Hubei University
Journal of Medical Humanities | Year: 2017

This essay applies Henri Lefebvre’s notion of the production of space, particularly his conceptualization of the tension formed by the perceived-conceived-lived triad to analyze how space is produced in wartime hospitals as demonstrated in Richard Selzer’s “The Whistlers’ Room.” Wounded soldiers participate in producing the triad of the social space of military hospitals through their multilayered performances as fighting soldiers serving the nation and as living human beings longing for human connections. Contradictory performances demonstrate the strategic positioning of wounded soldiers as active producers of different social spaces. By representing the lived spaces produced by wounded soldiers, Selzer challenges the hegemonic representations of the conceived spaces of military hospitals. Selzer’s exploration of soldiers’ contradictory performances opens up opportunities for discussion of writing physicians who assume a similar role by positioning themselves strategically within the medical institution. © 2017 Springer Science+Business Media New York


He R.,Hubei University | Wang Z.,Hubei University | Jin X.,Hubei University
Carbon | Year: 2017

A simple route to prepare graphitic carbon nanosheets (GCNSs) through thermal reaction between CO2 and calcium carbide (CaC2) is reported. The yield is about 85% at 700 °C according to the amount of CaC2 fed. The reaction encounters great kinetic difficulty at lower temperatures, while at higher temperatures, the yield would decrease due to the reaction between GCNSs and CO2. Spectroscopic analysis and morphologic observations demonstrate that the GCNSs have a thickness of about 10–50 nm and a lateral size of 1–10 μm. The as-prepared GCNSs delivered an initial reversible capacity of 513 mAh g−1 at a current density of 100 mA g−1 and a capacity of 494 mAh g−1 after 200 charge-discharge cycles in a potential range between 0.01 and 3.0 V vs. Li/Li+. It also showed a good rate performance with a reversible capacity of 293 mAh g−1 at 1000 mA g−1. These high performances can be linked to the special cambered crumpled structure of the GCNSs with some lattice defects, which ensure fast solid diffusion in addition to providing effective liquid channels in the electrode. Our findings promises an efficient route to convert the environmental carbon sources, including CO2, to high value GCNSs. © 2017 Elsevier Ltd


Cheng F.,Wuhan University | Li W.-X.,Hubei University | Xu C.-J.,University of Rouen
Mathematical Methods in the Applied Sciences | Year: 2017

In this paper, we consider the inviscid limit for the periodic solutions to Navier-Stokes equation in the framework of Gevrey class. It is shown that the lifespan for the solutions to Navier-Stokes equation is independent of viscosity, and that the solutions of the Navier-Stokes equation converge to that of Euler equation in Gevrey class as the viscosity tends to zero. Moreover, the convergence rate in Gevrey class is presented. © 2017 John Wiley & Sons, Ltd.


Zhang L.,Hubei University
Journal of Computational and Theoretical Nanoscience | Year: 2016

Bilateral negotiation based on agents is considered as a significant research issue in autonomous agent. There are also so many issues involved for the negotiators need to settle. In this paper, we propose a novel bilateral two-issue negotiation model that price and quantity are negotiated. Firstly, we construct the utility function of both agents and offer generation function. Then we propose an efficient negotiation algorithm which can reach an agreement aiming to maximize their owner's utility. A multiple and approximating offer method is introduced to handle non-monotonic utility functions. An important contribution of this paper is that we consider agents not necessarily to conflict over the quantity issue. The experimental results demonstrate the efficiency and effectiveness of the proposed negotiation model. Copyright © 2016 American Scientific Publishers All rights reserved.


Chen Y.,Hubei University | Jin Z.,Texas Southern University | Liu X.,Hubei University
Communications in Computer and Information Science | Year: 2017

When the service region of ports overlap, consignors’ selecting behaviors for shipping ports become homogeneous to commuters’ choosing behaviors on trips. The commuters’ travel behaviors can be described through a probabilistic model in transportation planning. In this study, we adopt the transportation probabilistic forecast model to forecast port throughput. First, we amend the model with a port attraction coefficient to forecast port throughput distributions between different ports. Then, forecast for each port throughput is obtained by reallocation of regional total port throughput to each nearby port. We use the port of Fuyang as an empirical research in this paper to validate the methodology. Results compared between this method and traditional regression model indicate that this method provides more persuasive reasoning. © Springer Nature Singapore Pte Ltd. 2017.


Li H.,Hubei University | Tang S.,Hubei University
International Journal of Simulation: Systems, Science and Technology | Year: 2016

Among the security issues in the environment of the Internet of things (IOT), the security of information source is a privilege to be protected. To protect data collection and control in IOT, the authenticity of information source must ascertained, therefore identity authentication technology is essential. In this paper, we propose an enhanced bidirectional authentication scheme suitable for Radio Frequency Identification (RFID) communications among devices or between devices and control devices. Specific improvement measures include three aspects: back-up terminals, a condition monitoring device to increase authentication properties, and an alarm mechanism. The enhanced bidirectional authentication protocol presented here has the characteristics of excellent performance in security and privacy protection, which could authenticate data contents, even positions and other data properties, and resist the replay or denial of service attacks. At the same time, it could overcome the defect of data asynchrony between the front and back ends, providing users with excellent forward security. The simulation experiments showed that system reliability was greatly enhanced by adopting the proposed protocol. © 2016, UK Simulation Society. All rights reserved.


Pan Y.,Hubei University of Medicine | Yuan Y.,Anyang Tumor Hospital | Liu G.,Nanchang University | Wei Y.,Hubei University
PLoS ONE | Year: 2017

Triple-negative breast cancer (TNBC) is an aggressive subgroup of breast cancer lack of effective target therapy. This study was to investigate the prognostic role of p53 and Ki-67 in 156 cases of TNBC patients. Logistic regression analysis was used to examine the association between clinical parameters and recurrence. Univariate and multivariate analyses were used to examine the association between clinical characteristics and disease-free survival (DFS) or overall survival (OS). Survival analyses using the Kaplan-Meier method were performed to examine the association between p53/Ki-67 and DFS and OS. Our data showed that p53 was positive in 71.3% and the Ki-67 high index was in 82.8% of TNBC. Elevated p53 and Ki-67 were associated with histological grade. The tumor size, lymph node involvement, and p53 expression are associated with risk of recurrence. Tumor size, lymph node involvement, family history, Ki-67 and p53 are independent variables associated with either DFS or OS. TNBC patients with positive p53 or Ki-67 high index or family history of cancer have a significant association with worse prognosis. This study suggests that p53, Ki-67 and family history are useful prognostic markers in TNBC. © 2017 Pan et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Liu Y.,Hubei University | Liu Y.,Hunan Agricultural University | Zou X.,Hubei University
Mathematical Biosciences | Year: 2017

In vitro, the recombinant HIV-1 Gag protein can generate spherical particles with a diameter of 25–30 nm in a fully defined system. It has approximately 80 building blocks, and its intermediates for assembly are abundant in geometry. Accordingly, there are a large number of nonlinear equations in the classical model. Therefore, it is difficult to compute values of geometry parameters for intermediates and make the mathematical analysis using the model. In this work, we develop a new model of HIV-like particle assembly in vitro by using six-fold symmetry of HIV-like particle assembly to decrease the number of geometry parameters. This method will greatly reduce computational costs and facilitate the application of the model. Then, we prove the existence and uniqueness of the positive equilibrium solution for this model with 79 nonlinear equations. Based on this model, we derive the interesting result that concentrations of all intermediates at equilibrium are independent of three important parameters, including two microscopic on-rate constants and the size of nucleating structure. Before equilibrium, these three parameters influence the concentration variation rates of all intermediates. We also analyze the relationship between the initial concentration of building blocks and concentrations of all intermediates. Furthermore, the bounds of concentrations of free building blocks and HIV-like particles are estimated. These results will be helpful to guide HIV-like particle assembly experiments and improve our understanding of the assembly dynamics of HIV-like particles in vitro. © 2017 Elsevier Inc.


Qiao J.,Hubei University | Hu B.Q.,Hubei University
Fuzzy Sets and Systems | Year: 2017

Overlap and grouping functions have been proposed by Bustince et al. for applications in image processing, classification problems and decision making based on fuzzy preference relations. In this paper, firstly, we generalize the concepts of overlap and grouping functions to the notions of interval overlap functions and interval grouping functions and investigate some vital related properties. In particular, we give the construction methods to obtain interval overlap functions and interval grouping functions, which are the best interval representation of the overlap and grouping functions, respectively. And then, we introduce the concepts of interval additive generators of interval overlap functions and interval grouping functions, which offer convenience for the selection of proper interval overlap functions or interval grouping functions in concrete problems. We also prove that the best interval representation of the additive generator pair of an additively generated overlap function is an interval additive generator pair of the best interval representation of this overlap function and the case for grouping function is analogous. © 2017 Elsevier B.V.


Luo J.,Hubei University | Jiang L.,Hubei University | Yang H.,University of New South Wales | Song B.-L.,Hubei University
Traffic | Year: 2017

Mammalian cells acquire most exogenous cholesterol through receptor-mediated endocytosis of low-density lipoproteins (LDLs). After internalization, LDL cholesteryl esters are hydrolyzed to release free cholesterol, which then translocates to late endosomes (LEs)/lysosomes (LYs) and incorporates into the membranes by co-ordinated actions of Niemann-Pick type C (NPC) 1 and NPC2 proteins. However, how cholesterol exits LEs/LYs and moves to other organelles remain largely unclear. Growing evidence has suggested that nonvesicular transport is critically involved in the post-endosomal cholesterol trafficking. Numerous sterol-transfer proteins (STPs) have been identified to mediate directional cholesterol transfer at membrane contact sites (MCSs) formed between 2 closely apposed organelles. In addition, a recent study reveals that lysosome-peroxisome membrane contact (LPMC) established by a non-STP synaptotagmin VII and a specific phospholipid phosphatidylinositol 4,5-bisphosphate also serves as a novel and important path for LDL-cholesterol trafficking. These findings highlight an essential role of MCSs in intracellular cholesterol transport, and further work is needed to unveil how various routes are regulated and integrated to maintain proper cholesterol distribution and homeostasis in eukaryotic cells. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd


He C.,Huazhong University of Science and Technology | Liu Z.,Hubei University | Peng H.,Huazhong University of Science and Technology | Yang Y.,South-Central University for Nationalities | And 2 more authors.
Electrochimica Acta | Year: 2016

Silver-doped graphene/MnO2 (SGM) hierarchical composites were readily fabricated by silver-ion-assisted room-temperature catalytic growth of urchin-like MnO2 spheres from the surface of graphene oxide (GO) followed by chemical reduction. This in-situ crafting strategy allows us to control the size of MnO2 spheres by tuning the concentration of silver ions in the reaction mixture. Graphene herein functions as a separator to prevent the agglomeration of MnO2 and a wrapper around MnO2 to avoid the electrochemical dissolution during charging/discharging cycles. MnO2 spheres grown from the surface of GO sheets ensure an intimate interface contact and large interface area between the two, and also prevent the stacking of graphene, thus affording open channels, high accessible surface, short diffusion paths of charges and high electrochemical utilization of the electrode. Furthermore, graphene sheets bridge a robust conductive network which facilitates fast transport of electrolyte ions and electrons throughout the electrode. As expected, an optimized SGM composite electrode delivers a much higher specific capacitance (∼273.1 F g−1 at 5 mV s−1, and ∼260 F g−1 at 0.2 A g−1) compared to the reduced GO (119.4 F g−1) and MnO2 (140.9 F g−1) counterparts. The retention of initial capacitance reaches 77.8% after a 20-fold increase in the scan rate, and remains 83.5% after 1200 cycles, indicating high rate capability and excellent cyclability. © 2016 Elsevier Ltd


Peng J.,Hubei University | Chen H.,Huazhong Agricultural University | Zhou Y.,University of Macau | Li L.,Hubei University
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing | Year: 2017

This paper proposes an ideal regularized composite kernel (IRCK) framework for hyperspectral image (HSI) classification. In learning a composite kernel, IRCK exploits spectral information, spatial information, and label information simultaneously. It incorporates the labels into standard spectral and spatial kernels by means of the ideal kernel according to a regularization kernel learning framework, which captures both the sample similarity and label similarity and makes the resulting kernel more appropriate for specific HSI classification tasks. With the ideal regularization, the kernel learning problem has a simple analytical solution and is very easy to implement. The ideal regularization can be used to improve and to refine state-of-the-art kernels, including spectral kernels, spatial kernels, and spectral-spatial composite kernels. The effectiveness of the proposed IRCK is validated on three benchmark hyperspectral datasets. Experimental results show the superiority of our IRCK method over the classical kernel methods and state-of-the-art HSI classification methods. © 2017 IEEE.


Zhao K.,Hubei University | Luo Y.,Hubei University | Xie J.,CAS Wuhan Institute of Geodesy and Geophysics
Geophysical Journal International | Year: 2017

In this study, we demonstrate the feasibility of imaging broad-band (10-150 s) Rayleigh wave phase velocity maps on a continental scale using ambient noise tomography (ANT).We obtain broad-band Rayleigh waves from cross-correlations of ambient noise data between all station pairs of USArray and measure the dispersion curves from these cross-correlations at a period band of 10-150 s. The large-scale dense USArray enables us to obtain over 500 000 surface wave paths which cover the contiguous United States densely. Using these paths, we generate Rayleigh wave phase velocity maps at 10-150 s periods. Our phase velocity maps are similar to other reported phase velocity maps based on ambient noise data at short periods (<50 s) and based on earthquake data at intermediate/long periods (50-90 s). This study extends ANT from short/intermediate periods (<50 s) to long periods up to 150 s in a continental scale of the USA. These broad-band phase velocity maps from ANT can be used to construct 3-D lithospheric and asthenospheric velocity structures. © The Authors 2016. Published by Oxford University Press on behalf of The Royal Astronomical Society.


Hui X.,Hubei University | Yu C.,Nantong University
Photonics Research | Year: 2017

In this work, we study the photonic band of cumulative Fibonacci lattices, of which the structure is composed of all generated units in a Fibonacci sequence. The results are compared with distributed Bragg reflector (DBR) structures with the same numbers of layers. Photonic bandgaps are found at two characteristic frequencies, symmetrically separated from the central bandgap in the DBR counterpart. Field amplitude and phase distribution in the Fibonacci lattice indicates an interferential origin of the bandgaps. Fourier transform on the refractive index profile is carried out, and the result confirms a determinate long-range periodicity that agrees well with the photonic band structure. © 2017 Chinese Laser Press.


Miao X.,Hubei University | Wang J.,Hubei University | Chen Y.,Hubei University
Journal of Pharmaceutical and Biomedical Analysis | Year: 2017

4,5-Dimethoxycanthin-6-one and 5-hydroxy-4-methoxycanthin-6-one are the active ingredients of P. quassiodes. In the present work, a LC–MS/MS method was developed for the determination of 4,5-dimethoxycanthin-6-one and its major metabolites 5-hydroxy-4-methoxycanthin-6-one (M1) and 4-hydroxy-5-methoxycanthin-6-one (M2) in rat plasma and tissues, and applied to study their pharmacokinetics and tissue distribution after intramuscular administration of 4,5-dimethoxycanthin-6-one to rats. By protein precipitation with methanol for plasma samples and liquid–liquid extraction with ethyl acetate for tissue samples, the analytes were separated on an ODS C18 column with a mobile phase consisted of methanol and water (0.1% formic acid), and quantified by a MS detector in positive multiple reaction monitoring (MRM) mode. MS transitions were m/z 281.0 → 167.1 for 4,5-dimethoxycanthin-6-one, m/z 267.0 → 168.1 for M1 and M2, m/z 251.0 → 195.1 for 3-methylcanthin-2,6-dione (IS). The pharmacokinetic results indicate that 4,5-dimethoxycanthin-6-one is absorbed rapidly (Tmax = 5.4–6.4 min), distributed rapidly and widely in the order of liver > kidney ≈ lung ≈ large intestine ≈ small intestine, and eliminated quickly (t1/2z = 64.9–77.7 min) following the intramuscular administration. Furthermore, M1 and M2 were detected only in rat plasma and liver at the indicated times after the intramuscular administration. © 2017 Elsevier B.V.


Microwave-assisted ferric chloride (FeCl3) pretreated rice straw was utilized for reducing sugars production and ethanol production with free and immobilized cells of Trichoderma viride and Sacharomyces cerevisiae. The maximum reducing sugars concentration (3.46 g/L) and YR/r (reducing sugars yield/rice straw consumption; 0.17 g/g) from pretreated rice straw with free cells of Trichoderma viride at 84 h were much higher than those from untreated rice straw (1.24 g/L, 0.06 g/g). Untreated and pretreated rice straw was converted to ethanol by free cells of Trichoderma viride and Sacharomyces cerevisiae. The maximum ethanol concentration from pretreated rice straw was 2.14 g/L representing the YE/r (ethanol yield/rice straw consumption) of 0.11 g/g, which was higher than those from untreated rice straw (1.13 g/L, 0.06 g/g). Pretreated rice straw was used to produce ethanol by free cells of Trichoderma viride and immobilized Sacharomyces cerevisiae, and by co-immobilized cells of Trichoderma viride and Sacharomyces cerevisiae. The maximum ethanol concentration obtained by co-immobilized Trichoderma viride and Sacharomyces cerevisiae was 2.75 g/L with the YE/r of 0.14 g/g at 84 h, which was higher than those achieved by free cells of Trichoderma viride and immobilized Sacharomyces cerevisiae (2.36 g/L, 0.12 g/g). Co-immobilized Trichoderma viride and Sacharomyces cerevisiae were reused five times in repeated batch experiments. The ethanol concentration and the YE/r in each batch were above 2.75 g/L and 0.14 g/g after 84 h, respectively. This proved the vitality and stability of co-immobilized Trichoderma viride and Sacharomyces cerevisiae. © 2016 American Society of Civil Engineers.


Yu Z.,Hubei University | Zhang Q.,Hubei University
Optics InfoBase Conference Papers | Year: 2016

A novel fiber-optics landslide monitoring system is proposed to achieve distributed, high-sensitivity and high-resolution strain measurement. The whole system adopts coherent OTDR technique to realize accurate monitoring with a resolution of 0.1με. © OSA 2016.


Wang P.,Hubei University | Tang S.,Hubei University | Huang P.,Hubei University | Lei A.,CAS Lanzhou Institute of Chemical Physics
Angewandte Chemie - International Edition | Year: 2017

An environmentally friendly electrocatalytic protocol has been developed for dehydrogenative C-H/S-H cross-coupling. This method enabled C-S bond formation under catalyst- and oxidant-free conditions. Under undivided electrolysis conditions, various aryl/heteroaryl thiols and electron-rich arenes afforded the C-S bond-formation products in 24-99% yield. A preliminary mechanistic study indicated that the generation of aryl radical cation intermediates is key to the success of this transformation. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.


Zhang H.,Hubei University | Dong Y.,Hubei University | Fan Q.,Hubei University
Signal Processing | Year: 2017

The recovery of sparse signal from noisy data arises in various application fields. One widely known approach for Gaussian noise image restoration with wavelet frame based sparse representation is the l0 norm regularized variational model. In this paper, the sparse and nonconvex noncontinuous l0 norm regularized model is proposed to recover the Poisson noise and blurred image. Then the resulted optimization problem is solved by the alternating direction method of multipliers(ADMM) scheme and two different approaches are adopted to solve the ADMM scheme in the numerical experiments. Extensive simulation results verify the convergence of the proposed algorithm and indicate that the proposed l0 norm based nonconvex model is efficient and comparable with some state-of-the-art approaches. © 2017 Elsevier B.V.


Chen Z.,Nanchang University | Wang J.-S.,Key Laboratory of Space Weather National Center for Space Weather | Deng Y.,University of Texas at Arlington | Huang C.-M.,Hubei University
Journal of Geophysical Research: Space Physics | Year: 2017

The spectral whitening method (SWM) has been previously proved to be very effective at identifying ionospheric disturbances on foF2 (the critical frequency of ionospheric F2 layer). To continuously investigate the strength of the new method, in this paper SWM has been used to extract the effect of geomagnetic activity on total electron content (TEC) and has been compared with the traditional 28day running median centered (RMC) method. First, ionospheric variations during quiet and disturbed conditions are analyzed by both SWM and RMC. The results from RMC, compared with those from SWM, overestimate the disturbance occurrence by about 5-20% during the geomagnetic storms and up to 35% during the quiet time. The possible reason is that the results can be contaminated by the residuals of periodic components in the RMC identified disturbances. Meanwhile, the power spectral analysis of the disturbance field shows that the annual and diurnal variations are still significant in RMC results but very weak in SWM results, which indicates that SWM has some advantage to clean up the background variation. Finally, the analysis of the spatial correlation of the disturbance field with F10.7 and Ap illustrates that the effects of solar and geomagnetic activities from SWM are significantly reduced and enhanced, respectively. It suggests that the SWM is more effective in extracting the effect of geomagnetic activity from TEC than RMC. The relative deviation of TEC derived by SWM is more sensitive to geomagnetic activity than solar activity. © 2017. American Geophysical Union. All Rights Reserved.


Tang S.,Hubei University | Gao X.,Hubei University | Lei A.,Hubei University | Lei A.,Jiangxi Normal University
Chemical Communications | Year: 2017

An electrocatalytic reaction protocol is developed for achieving intramolecular dehydrogenative annulation of N-aryl enamines. It offers a simple and efficient way for the synthesis of indoles in an undivided cell. Good to excellent yields are obtained under oxidant-free and transition-metal-free conditions. Moreover, imidazo[1,2-a]pyridines could also be produced when N-pyridyl enamines were used as the substrates. © 2017 The Royal Society of Chemistry.


CHEN Y.,University of Alberta | CHEN Y.,Hubei University
Journal of Biological Systems | Year: 2017

In theoretical ecology and community ecology, it is still unclear how phylogenetic community structure and species distributions are linked together. In this paper, a neutral model for evaluating phylogenetic constraints on species diversity and distribution patterns is developed to address these issues. To accomplish this, temporal species distribution and diversity patterns are evaluated and simulated by considering the impact of phylogenetic relatedness of species in a lattice landscape with square grids. A continuous patch for the resultant distributional range map of a species is defined as a group of grids in which the interior grids are adjacent to each other while the edge grids of the patch are isolated from other remaining grids in the range map. The adjacency or isolation of a grid with respect to another grid follows the von Neumann neighborhood criterion. The hypothesis tested is: phylogenetically closely related species tend to avoid each other (phylogenetic dilution), which produces a phylogenetic overdispersion pattern. In this case, all species have similar species abundances and distribution-patch size patterns. In contrast, if closely related species tend to associate together (phylogenetic concentration), a phylogenetic clustering pattern emerges: phylogenetically distinct species tend to have higher abundances and more large distribution patches. Using simulations, this paper presents results which demonstrate the reverse phenomenon: if it is assumed that phylogenetic relatedness of species is modeled as a dilution effect, the resultant distributional maps for evolutionarily distinct species present significantly increased numbers of continuous large patches. An evolutionarily distinct clade tends to have significantly higher relative abundance than other clades in all simulations. It was also found that if phylogenetic relatedness of species is modeled as a concentration effect, the simulated distributional map of each species would present a similar percentage of large patches for both evolutionarily unique and common clades for many cases when the community size is large enough. However, being similar to dilution effect, the resultant species relative abundance for evolutionarily unique clade is significantly higher than that for evolutionarily common clade. In conclusion, evolutionary distinct species will have more chances to survive with high populations and less fragmented distributional range in environments where the phylogenetic dilution effect is functioning. It is hoped that these results contributed to clarifying the complex associations generated by phylogenetic community structure in future ecological and evolutionary studies. © 2017 World Scientific Publishing Company


A growing body of evidence has indicated that long non-coding RNAs (lncRNAs) function as competing endogenous RNAs (ceRNAs) during tumorigenesis. In this study, the qRT-PCR results revealed that the lncRNA ferritin heavy chain 1 pseudogene 3 (FTH1P3) was over-expressed in oral squamous cell carcinoma (OSCC) and decreased the survival rate of OSCC patients. Ectopic expression of FTH1P3 facilitates cell proliferation and colony formation in OSCC cells. Moreover, FTH1P3 acted as a competitive endogenous RNA (ceRNA), effectively becoming sponge for miR-224-5p and thereby modulating the expression of fizzled 5. Importantly, expression analysis revealed that both FTH1P3 and fizzled 5 were up-regulated in OSCC cell lines and tissues, and over-expression of fizzled 5 also functioned as an oncogene in OSCC cells. Our data demonstrated FTH1P3 facilitated OSCC progression by acting as a molecular sponge of miR-224-5p to modulate fizzled 5 expression. Thus, targeting the ceRNA network referring FTH1P3 may be a therapeutic target for treatment of OSCC. © 2017 Elsevier B.V.


Huang X.,Hubei University
International Journal of Interactive Mobile Technologies | Year: 2016

Ant colony algorithm is a heuristic algorithm which is fit for solving complicated combination optimization. It showed great advantage on solving combinatorial optimization problem since it was proposed. The algorithm uses distributed parallel computing and positive feedback mechanism, and is easy to combine with other algorithms. This ant colony algorithm has already been widespread used in the field of discrete space optimization, however, is has been rarely used for continuous space optimization question. On the basis of basic ant colony algorithm principles and mathematical model, this paper proposes an ant colony algorithm for solving continuous space optimization question. Comparing with the ant colony algorithm, the new algorithm improves the algorithm in aspects of ant colony initialization, information density function, distribution algorithms, direction of ant colony motion, and so on. The new algorithm uses multiple optimization strategy, such as polynomial time reduction and branching factor, and improves the ant colony algorithm effectively.


Tong Y.,Hubei University | Han X.,Hubei University
Proceedings of SPIE - The International Society for Optical Engineering | Year: 2016

Inverted focometer is a transformation of the traditional focomete, and optical lens focal length is an important technical indicators of optical system.The inverted focometer was used to measure the optical lens focal length, an expression between the ruling span of poroo-plate glass and the focal length of measured optical system was deduced according to inverted focometer design, the S-F figure graphic representation was developed, the S-F graph which could express relation of data was obtained, and steps of designing poroo-plate glass were analyzed.The S-F figure graphic representation is simple, intuitive and easy to design. © 2016 SPIE.


Jin W.,Hubei University | Sun Y.,Hubei University
Pacific Asia Conference on Information Systems, PACIS 2015 - Proceedings | Year: 2015

Although there're studies that investigate the factors affecting the intention to purchase virtual items in virtual worlds, most of these studies focus on the technological factors that enhance user experience (e.g., social presence) while pay less attention to the social factors that facilitate user participation and involvement (e.g., user engagement). To fill this gap, taking MMORPGs as a kind of virtual world, this study examines both the impacts of technological factors and social factors from an integrative perspective of social presence and user engagement. A survey from 214 World of Warcraft players has been conducted to test the proposed research model. The results show that 1) both social presence and user engagement positively influence flow which further leads to intention to purchase virtual products 2) two technological factors interactivity and sociability affect social presence, and 3) two social factors social ties and social identity affect user engagement. Theoretical and practical implications of the study are also discussed.


Cao P.,Hubei University
Proceedings - 9th International Conference on Measuring Technology and Mechatronics Automation, ICMTMA 2017 | Year: 2017

With the development of education information, this paper expounds the reason why Wushu teaching system reform is imperative. In the teaching content, teaching methods, as well as teachers and other aspects of the problems need to reform. In order to promote the reform of martial arts teaching system, martial arts teachers should have the ability to use information and information technology, and martial arts knowledge and its ability to combine. Through the analysis of the teaching mode of information and communication technology, it is possible to update the existing martial arts teaching methods. In addition, the teaching effect of Wushu teaching and students' enthusiasm for Wushu have a significant promotion effect. © 2017 IEEE.


Chen I.-S.,Hubei University
Computers in Human Behavior | Year: 2017

This study examined the relationship between computer self-efficacy and learning performance and investigated learning engagement as a mediator of this relationship. The theoretical background is a combination of the conservation of resources (COR) theory and a theoretically extended job demands–resources model (JD-R model) proposed by Crawford, LePine, and Rich (2010). A daily diary design was carried out with 121 late-middle- and old-aged job seekers attending 10 computer cram schools. Participants completed a baseline questionnaire, seven daily diary questionnaires, and seven daily end-of-class computer skills examinations over the course of 1 week (N = 121∗7 = 847 occasions). The results of multi-level analyses showed that 1) computer self-efficacy is positively related to learning performance, 2) computer self-efficacy is positively related to learning engagement, 3) learning engagement is positively related to learning performance, and 4) learning engagement fully mediates the relationship between computer self-efficacy and learning performance. The theoretical contributions, research limitations, implications for future research, and practical implications of this study are discussed. © 2017 Elsevier Ltd


Binlin C.,Hubei University | Jianming F.,Hubei University
International Journal of Network Security | Year: 2017

Mobile social networks have become very popular in recent years. The popularity of mobile social networks has attracted a large number of companies to do marketing on it. However, the social marketing suffer from social bots, a kind of bot accounts. In this paper, SBDSF(social bots detection based on the number of shared friends), a social graph based approach is proposed to detect social bots . SBDSF use the feature of social graph to detect social bots. We measure the effectiveness of SBDSF, the result of evaluation shows that SBDSF can achieve 96.1% accuracy and 95.1% precision using the Neural Network classifier.


Ai Q.,Huazhong University of Science and Technology | Ai Q.,Hubei University | Chen P.,Huazhong University of Science and Technology | Feng Y.,Huazhong University of Science and Technology | Xu Y.,Huazhong University of Science and Technology
Journal of Applied Crystallography | Year: 2017

During the growth process of organic crystals, it is easy to induce thermal defects and impurities when using the conventional Bridgman technique. In the present study, a specially designed double-wall ampoule was used to solve this problem. High-quality p-terphenyl single crystals were successfully grown by the vertical Bridgman method with the improved ampoule. Powder X-ray diffraction analyses were performed to evaluate the crystallinity of the grown single crystals. Fluorescence spectrum studies show an enhancement of fluorescence properties due to the improvement in crystalline perfection. © 2017 International Union of Crystallography.


Sun K.-Y.,Hubei University | Peng T.,Hubei University | Chen Z.,Hubei University | Song P.,Hubei University | Zhou X.-H.,Hubei University
Aging | Year: 2017

Emerging studies have shown that long noncoding RNAs (lncRNAs) play critical roles in carcinogenesis and progression, including human nasopharyngeal carcinoma (NPC). The correlation between lncRNAs expression and NPC development has not been well identified in the recent literature. Recently, high-through put analysis reveals that LOC100129148 is highly expressed in NPC. However, whether the aberrant expression of LOC100129148 in NPC is corrected with tumorigenesis or prognosis has not been investigated. Herein, we identified that LOC100129148 was up-regulated in NPC tissues and cell lines, and higher expression of LOC100129148 resulted in a markedly poorer survival time. Over-expressed LOC100129148 favored, but silenced LOC100129148 hampered cell proliferation in NPC cells. Additionally, LOC100129148 enhanced the KLF12 expression through functioning as a competitive 'sponge' for miR-539-5p. Thus, our study reports a novel mechanism underlying NPC carcinogenesis, and provides a potential novel diagnosis and treatment biomarker for NPC.


Li M.,Hubei University
2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016 | Year: 2016

Generating robotic grasps for given tasks is a difficult problem. This paper proposes a learning-based approach to generate suitable partial power grasp for a set of tool-using tasks. First a number of valid partial power grasps are sampled in simulation and encoded as a probabilistic model, which encapsulates the relations among the task-specific contact, the graspable object feature and the finger joints. With the learned model, suitable grasps can be generated on-line given the task-specific contact. Moreover, a grasp adaptation strategy is proposed to locally adjust the specified contact in order to increase the grasp feasibility and also the quality of the final found grasp. We demonstrate the effectiveness of our approach using a 16 DOF robotic hand - Allegro Hand, on a variety of tool-using tasks. © 2016 IEEE.


Weixu Z.,Hubei University | Zhiyong Y.,Hubei University
2016 IEEE International Conference on Information and Automation, IEEE ICIA 2016 | Year: 2016

In the collective motion control of a robot swarm, physics-based approaches offer unique advantages. A virtual force field is assumed around each robot, and produces attractive or repulsive force to neighbouring robots. Yet physics-based approaches have some limitations, because a robot should have more complicated actions than a physical particle, and the force fields could bring unexpected local balances during foraging and obstacle avoiding. In this paper, we present a novel Azimuth-dependent and Flux-conserved Force Field (ADeFF) model, in which an azimuth-dependent force field is assumed around each robot and a flux-conserved force field around each obstacle and destination area. The azimuth-dependent force field allows the force to be set arbitrarily so that forces more than simply attraction and repulsion can be set to achieve more desired swarm configuration. The flux-conserved force field prevents local balances from happening during swarm foraging. Simulation results show that using the ADeFF model, homogeneous swarm can self-Arrange into lattice configurations which are difficult to achieve through previous physics-based approaches. And local balances can be effectively avoided using this new method. © 2016 IEEE.


Yang X.,Hubei University | Liu M.,Hubei University
Proceedings of the IEEE International Conference on Advanced Materials for Science and Engineering: Innovation, Science and Engineering, IEEE-ICAMSE 2016 | Year: 2016

Chinese ink animation occupies an important position in the world animation history, while its complex processes and painting techniques have always been the pride of Chinese people. With the advent of the digital age, the popularity of computer technology and network provides a new creative environment and platform for painting. Compared with traditional painting, computer painting not only is faster, more environmentally-friendly and more convenient, but also makes the artistic forms and types of animation more diverse. This paper will focus on the new trends of some new technology and development during the production of ink animation in the digital era. © 2016 IEEE.


Xuemei Y.,Hubei University
Proceedings of the IEEE International Conference on Advanced Materials for Science and Engineering: Innovation, Science and Engineering, IEEE-ICAMSE 2016 | Year: 2016

Ink animation demonstrates the blooming freshness, ethereal and refined effect of Chinese ink painting perfectly, greatly enhancing the artistic style of Chinese animation and its ways of manifestation, which wins worldwide respect for Chinese animation. However, the drawbacks of ink animation, two of which are complex process and long production period, make it difficult to promote. The application of digital painting technology not only greatly remedies this defect, but also lowers the production threshold of ink animation to a great deal. In this paper, the author mainly takes his own ink animation Elixir as an example to explain in detail the application of digital painting technology and related technology in the production of ink animation. © 2016 IEEE.


Man X.,Hubei University
Advanced Materials Research | Year: 2013

Nowadays, as a fast moving consumer good, beer is not male-dominated good anymore. Post 80's and 90's generation has crept into it and become a young potential market. In the context of this new market pattern, it calls for urgent consideration and solution to design unique product packaging that can meet visual needs of most young consumers and win huge success of market competition in current situation. © (2013) Trans Tech Publications, Switzerland.


Kuntner M.,Slovenian Academy of science and Arts | Gregoric M.,Slovenian Academy of science and Arts | Li D.,National University of Singapore | Li D.,Hubei University
Naturwissenschaften | Year: 2010

The architecture of vertical aerial orb webs may be affected by spider size and gravity or by the available web space, in addition to phylogenetic and/or developmental factors. Vertical orb web asymmetry measured by hub displacement has been shown to increase in bigger and heavier spiders; however, previous studies have mostly focused on adult and subadult spiders or on several size classes with measured size parameters but no mass. Both estimations are suboptimal because (1) adult orb web spiders may not invest heavily in optimal web construction, whereas juveniles do; (2) size class/developmental stage is difficult to estimate in the field and is thus subjective, and (3) mass scales differently to size and is therefore more important in predicting aerial foraging success due to gravity. We studied vertical web asymmetry in a giant orb web spider, Nephila pilipes, across a wide range of size classes/developmental stages and tested the hypothesis that vertical web asymmetry (measured as hub displacement) is affected by gravity. On a sample of 100 webs, we found that hubs were more displaced in heavier and larger juveniles and that spider mass explained vertical web asymmetry better than other measures of spider size (carapace and leg lengths, developmental stage). Quantifying web shape via the ladder index suggested that, unlike in other nephilid taxa, growing Nephila orbs do not become vertically elongated. We conclude that the ontogenetic pattern of progressive vertical web asymmetry in Nephila can be explained by optimal foraging due to gravity, to which the opposing selective force may be high web-building costs in the lower orb. Recent literature finds little support for alternative explanations of ontogenetic orb web allometry such as the size limitation hypothesis and the biogenetic law. © 2010 Springer-Verlag.


Lim M.L.M.,National University of Singapore | Li D.,National University of Singapore | Li D.,Hubei University
PLoS ONE | Year: 2013

Animal colour signals used in intraspecies communications can generally be attributed to a composite effect of structural and pigmentary colours. Notably, the functional role of iridescent coloration that is 'purely' structural (i.e., absence of pigments) is poorly understood. Recent studies reveal that iridescent colorations can reliably indicate individual quality, but evidence of iridescence as a pure structural coloration indicative of male quality during contests and relating to an individual's resource-holding potential (RHP) is lacking. In age- and size-controlled pairwise male-male contests that escalate from visual displays of aggression to more costly physical fights, we demonstrate that the ultraviolet-green iridescence of Cosmophasis umbratica predicts individual persistence and relates to RHP. Contest initiating males exhibited significantly narrower carapace band separation (i.e., relative spectral positions of UV and green hues) than non-initiators. Asymmetries in carapace and abdomen brightness influenced overall contest duration and escalation. As losers retreated upon having reached their own persistence limits in contests that escalated to physical fights, losers with narrower carapace band separation were significantly more persistence. We propose that the carapace UV-green iridescence of C. umbratica predicts individual persistence and is indicative of a male's RHP. As the observed UV-green hues of C. umbratica are 'pure' optical products of a multilayer reflector system, we suggest that intrasexual variations in the optical properties of the scales' chitin-air-chitin microstructures are responsible for the observed differences in carapace band separations. © 2013 Lim, Li.


Zhou H.,Hubei University | Wang T.,Hubei University | Wang T.,Peking University | Duan Y.Y.,Hubei University
Journal of Electroanalytical Chemistry | Year: 2013

Aiming to improve the charge transfer ability at the neural electrode interface, a new and simple method for amino-functionalization of carbon nanotubes (CNTs) has been attempted, and the amino-functionalized CNTs after quaternization were electrodeposited onto pretreated Pt microelectrodes using an 80 V cell voltage in anhydrous solvent. The formation of amino-functionalized CNTs and electrodeposition of the functionalized CNTs were confirmed by Fourier transform infrared (FT-IR) spectroscopy and SEM images respectively. The deposited electrodes exhibited a reduction by 91% in the electrode impedance at 1 kHz compared to smooth Pt electrodes. In addition, the CNT deposited electrodes possessed a large charge storage capacity, and provided an increased safe charge injection (Qinj) limit (1.6-2.0 mC/cm2) that is ten times higher than that of Pt electrodes. Electrochemical stability is another important characteristic required by neural electrodes. It was found that the CNT deposited microelectrodes were very stable during electrical stimulation, which is highly desirable for implantable neural electrodes. In summary, this study developed an easy and mild coating method for elevating the safe charge injection limit of neural microelectrodes, which can be applied to neural prostheses such as visual prostheses. © 2012 Elsevier B.V. All rights reserved.


Wu K.,Hubei University | Tian S.,Shanghai University of Sport | Zhou H.,University of California at Riverside | Wu Y.,University of California at Riverside
Biochemical Pharmacology | Year: 2013

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) exert pleiotropic effects on the cardiovascular system, in part through a decrease in reactive oxygen species (ROS) formation and reduction of vascular inflammation. To elucidate the molecular mechanisms involved in these effects, we investigated the effect of statins on TNF-α-induced ROS production, vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) expression in human aortic endothelial cells (HAECs). Exposure of HAECs to TNF-α caused production of ROS via Rac-1 membrane translocation and activation. The Rac-1 activation and ROS liberation mediated TNF-stimulated NF-κB activation and the subsequent VCAM-1 and ICAM-1 expression. Extracellular-signal-regulated kinase 5 (ERK5) plays a central role in inhibiting endothelial inflammation. Immune complex kinase assay of protein extracts from HAECs treated with atorvastatin revealed increased ERK5 activity in a time- and dose-dependent manner. In addition, pretreatment with atorvastatin inhibited TNF-α-induced ROS production and VCAM-1 and ICAM-1 expression. Chemical or genetic inhibition of ERK5 ablated the statins inhibition of Rac-1 activation, ROS formation, NF-κB, VCAM-1 and ICAM-1 expression induced by TNF-α. Taken together, statins, via ERK5 activation, suppress TNF-stimulated Rac-1 activation, ROS generation, NF-κB activation and VCAM-1 and ICAM-1 expression in human ECs, which provides a novel explanation for the pleiotropic effects of statins that benefit the cardiovascular system. © 2013 Elsevier Inc. All rights reserved.


Xiao C.,Hubei University | Liu M.,Hubei University | Xiao D.,Hubei University | Dong Z.,Cornell University | Ma K.-L.,University of California at Davis
IEEE Transactions on Circuits and Systems for Video Technology | Year: 2014

Image/video matting is one of the key operations in many image/video editing applications. Although previous methods can generate high-quality matting results, their high computational cost in processing high-resolution image and video data often limits their usability. In this paper, we present a unified acceleration method for closed-form image and video matting using a hierarchical data structure, which achieves an excellent compromise between quality and speed. We first apply a Gaussian KD tree to adaptively cluster the input high-dimensional image and video feature space into a low-dimensional feature space. Then, we solve the affinity-weighted Laplacian alpha matting in the reduced feature space. The final matting results are derived using detail-aware alpha interpolation. Our algorithm can be fully parallelized by exploiting advanced graphics hardware, which can further accelerate the matting computation. Our method accelerates existing methods by at least an order of magnitude with good quality, and also greatly reduces the memory consumption. This acceleration strategy is also extended to support other affinity-based matting approaches, which makes it a more general accelerating framework for a variety of matting methods. Finally, we apply the presented method to accelerate image and video dehazing, and image shadow detection and removal. © 2013 IEEE.


Xiang D.,Hubei University | Zhai K.,Hubei University | Xiang W.,Sichuan University of Arts and Science | Wang L.,Hubei University
Talanta | Year: 2014

A highly sensitive fluorescence method of quantitative detection for specific DNA sequence is developed based on molecular beacon (MB) and nucleic acid dye SYBR Green I by synchronous fluorescence analysis. It is demonstrated by an oligonucleotide sequence of wild-type HBV (target DNA) as a model system. In this strategy, the fluorophore of MB is designed to be 6-carboxyfluorescein group (FAM), and the maximum excitation wavelength and maximum emission wavelength are both very close to that of SYBR Green I. In the presence of targets DNA, the MBs hybridize with the targets DNA and form double-strand DNA (dsDNA), the fluorophore FAM is separated from the quencher BHQ-1, thus the fluorophore emit fluorescence. At the same time, SYBR Green I binds to dsDNA, the fluorescence intensity of SYBR Green I is significantly enhanced. When targets DNA are detected by synchronous fluorescence analysis, the fluorescence peaks of FAM and SYBR Green I overlap completely, so the fluorescence signal of system will be significantly enhanced. Thus, highly sensitive fluorescence quantitative detection for DNA can be realized. Under the optimum conditions, the total fluorescence intensity of FAM and SYBR Green I exhibits good linear dependence on concentration of targets DNA in the range from 2×10 -11 to 2.5×10-9 M. The detection limit of target DNA is estimated to be 9×10-12 M (3σ). Compared with previously reported methods of detection DNA with MB, the proposed method can significantly enhance the detection sensitivity. © 2014 Elsevier B.V.


Yuan Q.,Hunan University | Yuan Q.,University of Florida | Yuan Q.,Hubei University | Zhang Y.,University of Florida | And 8 more authors.
ACS Nano | Year: 2012

Herein a photon-manipulated mesoporous release system was constructed based on azobenzene-modified nucleic acids. In this system, the azobenzene- incorporated DNA double strands were immobilized at the pore mouth of mesoporous silica nanoparticles. The photoisomerization of azobenzene induced dehybridization/hybridization switch of complementary DNA, causing uncapping/capping of pore gates of mesoporous silica. This nanoplatform permits holding of guest molecules within the nanopores under visible light but releases them when light wavelength turns to the UV range. These DNA/mesoporous silica hybrid nanostructures were exploited as carriers for the cancer cell chemotherapy drug doxorubicin (DOX) due to its stimuli-responsive property as well as good biocompatibility via MTT assay. It is found that the drug release behavior is light-wavelength-sensitive. Switching of the light from visible to the UV range uncapped the pores, causing the release of DOX from the mesoporous silica nanospheres and an obvious cytotoxic effect on cancer cells. We envision that this photocontrolled drug release system could find potential applications in cancer therapy. © 2012 American Chemical Society.


Kuntner M.,Hubei University | Kuntner M.,Smithsonian Institution
Molecular Ecology Resources | Year: 2015

The philosophical basis and utility of DNA barcoding have been a subject of numerous debates. While most literature embraces it, some studies continue to question its use in dipterans, butterflies and marine gastropods. Here, we explore the utility of DNA barcoding in identifying spider species that vary in taxonomic affiliation, morphological diagnosibility and geographic distribution. Our first test searched for a 'barcoding gap' by comparing intra- and interspecific means, medians and overlap in more than 75 000 computed Kimura 2-parameter (K2P) genetic distances in three families. Our second test compared K2P distances of congeneric species with high vs. low morphological distinctness in 20 genera of 11 families. Our third test explored the effect of enlarging geographical sampling area at a continental scale on genetic variability in DNA barcodes within 20 species of nine families. Our results generally point towards a high utility of DNA barcodes in identifying spider species. However, the size of the barcoding gap strongly depends on taxonomic groups and practices. It is becoming critical to define the barcoding gap statistically more consistently and to document its variation over taxonomic scales. Our results support models of independent patterns of morphological and molecular evolution by showing that DNA barcodes are effective in species identification regardless of their morphological diagnosibility. We also show that DNA barcodes represent an effective tool for identifying spider species over geographic scales, yet their variation contains useful biogeographic information. © 2014 John Wiley & Sons Ltd.


Feng J.,Shandong University | Ma P.,Shandong University | Yang H.,Hubei University | Lu L.,National University of Singapore
Electrochimica Acta | Year: 2013

The compatibility with graphitic anode has been one key problem in developing flame-retarding additives for lithium ion batteries. To understand the interactions between flame-retarding additives and graphitic anode, two phosphonate esters (dimethyl methylphosphonate DMMP and diethyl ethylphosphonate DEEP) are selected and characterized as flame retardant addtives. DEEP is reported as a flame-retarding additive for the first time. Their interactions with graphite anode are characterized via current-static charge-discharge, ex-situ XRD, FE-SEM and AC impedance. The results reveal that the two phosphonate esters demonstrate different reaction mechanisms with graphitic anode, which result in different anode compatibility. These findings may be useful for designing better flame-retarding additives for lithium ion batteries. © 2013 Elsevier Ltd. All rights reserved.


Yu J.,Hubei University | Yu J.,CAS Wuhan Institute of Virology | Zhou X.,Peking University
Angewandte Chemie - International Edition | Year: 2011

Switched: The metal complex [Ru(dip) 2dppz] 2+ can induce the transition from B-DNA to Z-DNA and stabilize the Z conformation in aqueous low-salt solution (see scheme; dip=4,7-diphenyl-1,10-phenanthroline, dppz=dipyridophenazine). The transition is sequence-independent (including non-alternating pyrimidine-purine and AT-rich sequences) and was monitored by CD and 2D NMR spectroscopy, AFM, isothermal titration calorimetry, and gel electrophoresis. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Zhang X.,Hubei University | Yang Z.,University of Victoria | Li X.,Hubei University | Deng N.,Hubei University | Qian S.,Hubei University
Chemical Communications | Year: 2013

This work revealed that β-cyclodextrin was attached onto the surface of TiO2 predominately by its secondary ring side, which caused paradoxical functions of β-cyclodextrin in the photodegradation of the four bisphenols. The equilibrium between the guest adsorbed through β-cyclodextrin onto TiO2 and the one locked in β-CD in water could also change the role of β-cyclodextrin in the degradation of a certain guest. © 2013 The Royal Society of Chemistry.


Yang Z.,CAS Institute of Biophysics | Liang H.,CAS Institute of Biophysics | Zhou Q.,Hubei University | Li Y.,Hubei University | And 6 more authors.
Cell Research | Year: 2012

Interferon-stimulated gene 56 (ISG56) family members play important roles in blocking viral replication and regulating cellular functions, however, their underlying molecular mechanisms are largely unclear. Here, we present the crystal structure of ISG54, an ISG56 family protein with a novel RNA-binding structure. The structure shows that ISG54 monomers have 9 tetratricopeptide repeat-like motifs and associate to form domain-swapped dimers. The C-terminal part folds into a super-helical structure and has an extensively positively-charged nucleotide-binding channel on its inner surface. EMSA results show that ISG54 binds specifically to some RNAs, such as adenylate uridylate (AU)-rich RNAs, with or without 5′ triphosphorylation. Mutagenesis and functional studies show that this RNA-binding ability is important to its antiviral activity. Our results suggest a new mechanism underlying the antiviral activity of this interferon-inducible gene 56 family member. © 2012 IBCB, SIBS, CAS All rights reserved.


Ke J.,Hubei University | Tang Y.,Hubei University | Yi H.,Hubei University | Li Y.,Nanjing University of Posts and Telecommunications | And 4 more authors.
Angewandte Chemie - International Edition | Year: 2015

The selective radical/radical cross-coupling of two different organic radicals is a great challenge due to the inherent activity of radicals. In this paper, a copper-catalyzed radical/radical Csp3-H/P-H cross-coupling has been developed. It provides a radical/radical cross-coupling in a selective manner. This work offers a simple way toward β-ketophosphonates by oxidative coupling of aryl ketone o-acetyloximes with phosphine oxides using CuCl as catalyst and PCy3 as ligand in dioxane under N2 atmosphere at 130 C for 5 h, and yields ranging from 47% to 86%. The preliminary mechanistic studies by electron paramagnetic resonance (EPR) showed that, 1) the reduction of ketone o-acetyloximes generates iminium radicals, which could isomerize to α-sp3-carbon radical species; 2)phosphorus radicals were generated from the oxidation of phosphine oxides. Various aryl ketone o-acetyloximes and phosphine oxides were suitable for this transformation. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Huang L.,Hubei University | Huang L.,China National Institute of Biological Sciences | Yin P.,Hubei University | Zhu X.,China National Institute of Biological Sciences | And 3 more authors.
Nucleic Acids Research | Year: 2011

Plasmid pCXC100 from the Gram-positive bacterium Leifsonia xyli subsp. cynodontis uses a type Ib partition system that includes a centromere region, a Walker-type ATPase ParA and a centromere-binding protein ParB for stable segregation. However, ParB shows no detectable sequence homology to any DNA-binding motif. Here, we study the ParB centromere interaction by structural and biochemical approaches. The crystal structure of the C-terminal DNA-binding domain of ParB at 1.4 resolution reveals a dimeric ribbon-helix-helix (RHH) motif, supporting the prevalence of RHH motif in centromere binding. Using hydroxyl radical footprinting and quantitative binding assays, we show that the centromere core comprises nine uninterrupted 9-nt direct repeats that can be successively bound by ParB dimers in a cooperative manner. However, the interaction of ParB with a single subsite requires 18 base pairs covering one immediate repeat as well as two halves of flanking repeats. Through mutagenesis, sequence specificity was determined for each position of an 18-bp subsite. These data suggest an unique centromere recognition mechanism by which the repeat sequence is jointly specified by adjacent ParB dimers bound to an overlapped region. © 2011 The Author(s).


Yi M.,National University of Singapore | Yi M.,Hubei University | Hong N.,National University of Singapore | Hong Y.,National University of Singapore | Hong Y.,Chinese Academy of Sciences
Nature Protocols | Year: 2010

Embryonic stem (ES) cells are pluripotent cells capable of differentiation into various cell types. Haploid ES cells elegantly combine the advantages of haploidy and pluripotency and offer a unique in vitro system for genetic analyses of molecular, cellular and developmental events in various cell lineages. Our recent success in generating haploid ES cell lines from gynogenetic embryos of the medaka fish suggests that haploidy can support ES cell derivation and maintenance in a vertebrate. In this study, we present a step-by-step protocol for derivation and characterization of medaka haploid ES cells. We have used this procedure to produce three haploid ES cell lines from five primary cultures. It takes about 15 weeks to generate stable cultures, 5g-8 weeks to obtain pure haploid cells and 5-6 weeks to characterize ES cells in vitro and in vivo. © 2010 Nature America, Inc. All rights reserved.


Yang Z.,University of Victoria | Zhang X.,Hubei University | Cui J.,Hubei University
Applied Catalysis B: Environmental | Year: 2014

In this work, an efficient and simple supramolecular approach to introduce cyclodextrin on TiO2 was demonstrated using the protocatechuic acid functionalized β-cyclodextrin (PCA-β-CD) that had a bioinspired catecholic structure. Two types of PCA-β-CD/TiO2 heterosupramolecules were obtained through a facile dip coating of TiO2 nanoparticles (Hombikat UV-100 and Fe3O4@SiO2@TiO2) in PCA-β-CD aqueous solution. The high surface coverage of Hombikat UV-100 or Fe3O4@SiO2@TiO2 by the attached PCA-β-CD was calculated to be 49.4% or 74.2% in the PCA-β-CD/TiO2 based on the TGA results, and it was also confirmed by the optical properties study that PCA-β-CD located onto the TiO2 surface mainly through the coordination of the catechol part on the cyclodextrin small ring side and TiO2. Compared with the adsorption amount onto bare UV-100 and Fe3O4@SiO2@TiO2, the adsorption of bisphenol A onto PCA-β-CD/UV-100 and PCA-β-CD/Fe3O4@SiO2@TiO2 was 6.9 and 7.9 times higher, respectively, because of the high inclusion affinity between PCA-β-CD's cavity and bisphenol A. Moreover, the two PCA-β-CD/TiO2 heterosupramolecules showed a high photoactivity to bisphenol A under light irradiation extending to the visible-light range. The cyclic use and X-ray photoelectron spectroscopy analysis results revealed that the PCA-β-CD layer in PCA-β-CD/TiO2 was stable and that the catalyst possessed reusable properties. © 2013 Elsevier B.V.


Li X.,German Research Center for Geosciences | Li X.,Hubei University | Ge M.,German Research Center for Geosciences | Guo B.,Hubei University | And 2 more authors.
Geophysical Research Letters | Year: 2013

High-rate Global Navigation Satellite Systems (GNSS) has an increasing number of applications in geohazard monitoring. GNSS-derived displacements can provide important information for magnitude estimation and fault slip inversion, which is critical for seismic and tsunamigenic hazard mitigation. In this paper, we propose a new approach to quickly capture coseismic displacements with a single GNSS receiver in real time. The new approach can overcome the convergence problem of precise point positioning, and also avoids the integration process of the variometric approach. Using the results of the 2011 Tohoku-Oki earthquake, it is demonstrated that the proposed method can provide accurate displacement waveforms and permanent coseismic offsets at an accuracy of few centimeters, and can also reliably recover the moment magnitude and fault slip distribution. Key Points quickly capture seismic displacements with single GPS receiver in real-time It overcome convergence of PPP and integration process of variometric approach It provides accurate waveforms,permanent offsets,magnitude,slip distribution ©2013. American Geophysical Union. All Rights Reserved.


Gou S.-J.,Peking University | Yuan J.,Peking University | Yuan J.,Hubei University | Chen M.,Peking University | And 2 more authors.
Kidney International | Year: 2013

Studies in animal models suggest that complement activation is crucial in the pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV). Here we investigate the circulating complement activation profile of 66 patients with active stage AAV compared to that of 54 patients with AAV in remission. Plasma levels of C3a, C5a, soluble C5b-9, and Bb, all determined by enzyme-linked immunosorbent assay, were significantly higher in active stage than in remission of AAV, while plasma levels of properdin were significantly lower in the former than the latter disease stage. There was no significant difference in the plasma levels of C4d between active stage and remission. The plasma level of Bb in patients with active AAV significantly correlated with the proportion of total and cellular crescents in the renal biopsy, the erythrocyte sedimentation rate, and the Birmingham Vasculitis Activity Scores. Thus, systemic activation of complement by the alternative pathway takes place in human AAV. Circulating Bb might be a useful biomarker in assessing disease activity of AAV. © 2012 International Society of Nephrology.


Li X.,German Research Center for Geosciences | Li X.,Hubei University | Ge M.,German Research Center for Geosciences | Zhang H.,Hubei University | Wickert J.,German Research Center for Geosciences
Journal of Geodesy | Year: 2013

In order to improve the performance of precise point positioning (PPP), this paper presents a new data processing scheme to shorten the convergence time and the observation time required for a reliable ambiguity-fixing. In the new scheme, L1 and L2 raw observations are used and the slant ionospheric delays are treated as unknown parameters. The empirical spatial and temporal constraints and the ionospheric delays derived from a real-time available ionospheric model are all considered as pseudo-observations into the estimation for strengthening the solution. Furthermore, we develop a real-time computational procedure for generating uncalibrated phase delays (UPDs) on L1 and L2 frequencies. The PPP solution is first carried out on all reference stations based on the proposed scheme, undifferenced float ambiguities on L1 and L2 frequencies can be directly obtained from the new scheme. The L1 and L2 UPDs are then generated and broadcasted to users in real-time. This data product and also the performance of the new PPP scheme are evaluated. Our results indicate that the new processing scheme considering ionospheric characteristics can reduce the convergence time by about 30 % for float kinematic solutions. The observation time for a reliable ambiguity-fixing is shortened by 25 % compared to that of the traditional ambiguity-fixed kinematic solution. When the new method is used for static reference stations, the observation time for ambiguity-fixing is about 10 min in static mode and only 5 min if the coordinates are fixed to well-known values. © 2013 Springer-Verlag Berlin Heidelberg.


Wu Y.,University of California at Riverside | Zhou H.,University of California at Riverside | Wu K.,Hubei University | Lee S.,University of California at Riverside | And 3 more authors.
Antioxidants and Redox Signaling | Year: 2014

Aim: Oxidative stress induced by free fatty acids (FFA) contributes to metabolic syndrome-associated development of cardiovascular diseases, yet molecular mechanisms remain poorly understood. This study aimed at establishing whether phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and its subcellular location play a role in FFA-induced endothelial oxidative stress. Results: Exposing human endothelial cells (ECs) with FFA activated mammalian target of rapamycin (mTOR)/S6K pathway, and upon activation, S6K directly phosphorylated PTEN at S380. Phosphorylation of PTEN increased its interaction with its deubiquitinase USP7 in the nucleus, leading to PTEN deubiquitination and nuclear export. The reduction of PTEN in the nucleus, in turn, decreased p53 acetylation and transcription, reduced the expression of the p53 target gene glutathione peroxidase-1 (GPX1), resulting in reactive oxygen species (ROS) accumulation and endothelial damage. Finally, C57BL/6J mice fed with high-fat atherogenic diet (HFAD) showed PTEN nuclear export, decreased p53 and GPX1 protein expressions, elevated levels of ROS, and significant lesions in aortas. Importantly, inhibition of mTOR or S6K effectively blocked these effects, suggesting that mTOR/S6K pathway mediates HFAD-induced oxidative stress and vascular damage via PTEN/p53/GPX1 inhibition in vivo. Innovation: Our study demonstrated for the first time that S6K directly phosphorylated PTEN at S380 under high FFA conditions, and this phosphorylation mediated FFA-induced endothelial oxidative stress. Furthermore, we showed that S380 phosphorylation affected PTEN monoubiquitination and nuclear localization, providing the first example of coordinated regulation of PTEN nuclear localization via phosphorylation and ubiquitination. Conclusion: Our studies provide a novel mechanism by which hyperlipidemia causes vascular oxidative damage through the phosphorylation of PTEN, blocking of PTEN nuclear function, and inhibition of p53/GPX1 activity. Antioxid. © Copyright 2014, Mary Ann Liebert, Inc. 2014.


Tang Y.Y.,University of Macau | Yuan H.,University of Macau | Li L.,Hubei University
IEEE Transactions on Geoscience and Remote Sensing | Year: 2014

A sparsity-based model has led to interesting results in hyperspectral image (HSI) classification. Sparse representation from a test sample is used to identify the class label. However, an l1-based sparse algorithm sometimes yields unstable sparse representation. Inspired by recent progress in manifold learning, two manifold-based sparse representation algorithms are proposed to exploit the local structure of the test samples in corresponding sparse representations for enforcing smoothness across neighboring samples' sparse representations. Using techniques from regularization and local invariance, two manifold-based regularization terms are incorporated into the l1-based objective function. Extensive experiments show that our proposed algorithms obtain excellent classification performance on three classic HSIs. © 2014 IEEE.


Peng J.,Hubei University | Li L.,Hubei University | Tang Y.Y.,University of Macau
Chemometrics and Intelligent Laboratory Systems | Year: 2013

The key point in multivariate calibration is to build an accurate regression relationship between the predictors and responses. In this paper, we first use extreme learning machine (ELM) to build spectroscopy regression model. Then, we propose a combinational ELM (CELM) method in which the decision function is represented as a sum of a linear hidden-node output function (activation function) and a nonlinear hidden-node output function. As the output functions map the input spectral signal to linear and nonlinear feature spaces respectively, the proposed method can effectively describe the linear and nonlinear relations existed in spectroscopy regression by the CELM output weights vector which can be simply resolved by ridge least squares or alternative iterative regularization. The proposed method is compared, in terms of RMSEP, to PLS and ELM on simulated and real NIR data sets. Experimental results demonstrate the efficacy and effectiveness of the proposed method. © 2012 Elsevier B.V.


Wu D.,Hubei University | Long M.,Shanghai JiaoTong University
Surface and Coatings Technology | Year: 2011

While extending the application of TiO2 to substrates with low thermal resistance, enhanced visible-light activity of the self-cleaning TiO2-coated cotton fabrics has been realized by loading AgI particles. Several characterization tools, such as X-ray powder diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and UV-vis diffuse reflectance spectroscopy, were employed to study the phase structures, morphologies and optical properties of the samples. The photocatalytic properties of the prepared products were measured with the degradation of methyl orange at room temperature under visible light irradiation. In comparison with TiO2-cotton fabrics, the dramatic enhancement in the visible light photocatalytic performance of the AgI-TiO2-cotton fabrics could be attributed to AgI with narrow band gap and the effective electron-hole separations at the interfaces of the two semiconductors. The photocatalytic performances of the AgI-TiO2-cotton fabrics were maintained for the cycling experiments. In addition, based on the XRD patterns of the AgI-TiO2-cotton fabrics before and after reaction, AgI was stable in the composites under visible irradiation, indicating that AgI-TiO2-cotton fabrics could be used as stable and efficient visible-light-induced self-cleaning materials. © 2011 Elsevier B.V.


Zhou T.,University of Wollongong | Zhou T.,Hubei University | Pang W.K.,University of Wollongong | Pang W.K.,Australian Nuclear Science and Technology Organization | And 6 more authors.
ACS Nano | Year: 2014

Structural phase transitions can be used to alter the properties of a material without adding any additional elements and are therefore of significant technological value. It was found that the hexagonal-SnS2 phase can be transformed into the orthorhombic-SnS phase after an annealing step in an argon atmosphere, and the thus transformed SnS shows enhanced sodium-ion storage performance over that of the SnS2, which is attributed to its structural advantages. Here, we provide the first report on a SnS@graphene architecture for application as a sodium-ion battery anode, which is built from two-dimensional SnS and graphene nanosheets as complementary building blocks. The as-prepared SnS@graphene hybrid nanostructured composite delivers an excellent specific capacity of 940 mAh g-1and impressive rate capability of 492 and 308 mAh g-1 after 250 cycles at the current densities of 810 and 7290 mA g-1, respectively. The performance was found to be much better than those of most reported anode materials for Na-ion batteries. On the basis of combined ex situ Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and ex situ X-ray diffraction, the formation mechanism of SnS@graphene and the synergistic Na-storage reactions of SnS in the anode are discussed in detail. The SnS experienced a two-structural-phase transformation mechanism (orthorhombic-SnS to cubic-Sn to orthorhombic-Na3.75Sn), while the SnS2 experienced a three-structural-phase transformation mechanism (hexagonal-SnS2 to tetragonal-Sn to orthorhombic-Na3.75Sn) during the sodiation process. The lesser structural changes of SnS during the conversion are expected to lead to good structural stability and excellent cycling stability in its sodium-ion battery performance. These results demonstrate that the SnS@graphene architecture offers unique characteristics suitable for high-performance energy storage application. © 2014 American Chemical Society.


Chen Z.-W.,Shanghai JiaoTong University | Liu B.,Hubei University | Tang N.-W.,Shanghai JiaoTong University | Xu Y.-H.,Shanghai JiaoTong University | And 6 more authors.
Nucleic Acids Research | Year: 2014

Human single-strand (ss) DNA binding proteins 1 (hSSB1) has been shown to participate in DNA damage response and maintenance of genome stability by regulating the initiation of ATM-dependent signaling. ATM phosphorylates hSSB1 and prevents hSSB1 from ubiquitin-proteasome-mediated degradation. However, the E3 ligase that targets hSSB1 for destruction is still unknown. Here, we report that hSSB1 is the bona fide substrate for an Fbxl5-containing SCF (Skp1-Cul1-F box) E3 ligase. Fbxl5 interacts with and targets hSSB1 for ubiquitination and degradation, which could be prevented by ATM-mediated hSSB1 T117 phosphorylation. Furthermore, cells overexpression of Fbxl5 abrogated the cellular response to DSBs, including activation of ATM and phosphorylation of ATM targets and exhibited increased radiosensitivity, chemosensitivity and defective checkpoint activation after genotoxic stress stimuli. Moreover, the protein levels of hSSB1 and Fbxl5 showed an inverse correlation in lung cancer cells lines and clinical lung cancer samples. Therefore, Fbxl5 may negatively modulate hSSB1 to regulate DNA damage response, implicating Fbxl5 as a novel, promising therapeutic target for lung cancers. © 2014 The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.


Chen Z.,Hubei University | Zhou M.,Hubei University | Cao Y.,Hubei University | Cao Y.,Pacific Northwest National Laboratory | And 3 more authors.
Advanced Energy Materials | Year: 2012

A simple ball-milling method is used to synthesize a tin oxide-silicon carbide/few-layer graphene core-shell structure in which nanometer-sized SnO 2 particles are uniformly dispersed on a supporting SiC core and encapsulated with few-layer graphene coatings by in situ mechanical peeling. The SnO 2-SiC/G nanocomposite material delivers a high reversible capacity of 810 mA h g -1 and 83% capacity retention over 150 charge/discharge cycles between 1.5 and 0.01 V at a rate of 0.1 A g -1. A high reversible capacity of 425 mA h g -1 also can be obtained at a rate of 2 A g -1. When discharged (Li extraction) to a higher potential at 3.0 V (vs. Li/Li +), the SnO 2-SiC/G nanocomposite material delivers a reversible capacity of 1451 mA h g -1 (based on the SnO 2 mass), which corresponds to 97% of the expected theoretical capacity (1494 mA h g -1, 8.4 equivalent of lithium per SnO 2), and exhibits good cyclability. This result suggests that the core-shell nanostructure can achieve a completely reversible transformation from Li 4.4Sn to SnO 2 during discharging (i.e., Li extraction by dealloying and a reversible conversion reaction, generating 8.4 electrons). This suggests that simple mechanical milling can be a powerful approach to improve the stability of high-performance electrode materials involving structural conversion and transformation. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Yu J.,Chongqing University of Posts and Telecommunications | Hu H.,Hubei University | Zhou S.,Chongqing University | Lin X.,Chongqing University
Automatica | Year: 2013

In this paper, the stability of multi-variable fractional order nonlinear dynamic system is investigated. We propose the definition of generalized Mittag-Leffler stability with multi-variable and introduce the fractional Lyapunov direct method with multi-variable. Meanwhile, a novel approach is suggested to study generalized Mittag-Leffler stability in multi-variable fractional order nonlinear dynamic systems. An interesting multi-variable fractional order Lotka-Volterra predator-prey model is used to illustrate the proposed method and its effectiveness. © 2013 Elsevier Ltd. All rights reserved.


Feng C.,Hubei University | Li L.,Hubei University | Guo Z.,University of Wollongong | Li H.,Hubei University
Journal of Alloys and Compounds | Year: 2010

Nanocomposites composed of tin dioxide/multiwall carbon nanotubes (MWCNTs) were synthesized by a chemical precipitation method. The content of SnO 2 in the nanocomposites was adjusted by changing the mass ratio of SnCl4·4H2O to MWCNTs. The crystalline structure and morphology of the as-prepared samples were characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The electrochemical properties of the composites were investigated with a battery testing system. The results show that the electrochemical performance of a composite is strongly dependent on the content of SnO2 in the composites. A nanocomposite containing 50 wt.% of SnO2 gave the best performance, exhibiting relatively higher reversible capacity (523 mAh/g) and excellent cycling ability. The possible reasons why the composite has such an outstanding electrochemical performance are discussed also. © 2010 Published by Elsevier B.V.


He Z.,Hubei University | He Z.,Centers for Disease Control and Prevention | Zhu H.,Centers for Disease Control and Prevention | Zhou P.,Hubei University
Journal of Fluorescence | Year: 2012

This paper describes the development of a simplified and rapid method for the aqueous synthesis of quantum dots (QDs) with CdTe cores and gradient CdS external shells (CdTe/CdS QDs) aided by microwave irradiation. Several synthesis parameters, such as molar ratio of reagents, pH, reaction temperature, and reaction time, were studied in details. Under the optimized conditions, highly effective CdTe/CdS QDs could be synthesized in aqueous phase in only 15 min. In order to improve the biocompatibility of the CdTe/CdS QDs, these QDs were then interacted with carboxymethyl chitosan (CMC) so as they could be used as fluorescent probes in the aqueous phase. With the incorporation of CMC, the stability of modified QDs was found to have improved significantly (from 4 months to more than 10 months at room temperature). The photoluminescence quantum yield (PLQY) of the modified QDs could reach 75%, other parameters include a full width at half maximum of the emission (FWHM) spectrum as 40~60 nm, and an average size, estimated from electron microscopic images, as 3.5 nm. As fluorescent probes, these modified QDs were successfully used for imaging live Madin-Darby canine kidney (MDCK) cells, in which the preliminary results indicated that these modified QDs demonstrated good biocompatibility and showed promising applications for bio-labeling and imaging. © 2011 Springer Science+Business Media, LLC.


Wei H.,University of Cincinnati | Wei H.,East China Institute of Technology | Shen J.,University of Cincinnati | Shen J.,Hubei University | And 5 more authors.
Earth-Science Reviews | Year: 2015

The recovery of marine ecosystems following a mass extinction event involves an extended interval of increasing biotic diversity and ecosystem complexity. The pace of recovery may be controlled by intrinsic ecosystem or extrinsic environmental factors. Here, we present an analysis of changes in marine conditions following the end-Permian mass extinction with the objective of evaluating the role of environmental factors in the protracted (~. 5-Myr-long) recovery of marine ecosystems during the Early Triassic. Specifically, our study examines changes in weathering, productivity, and redox proxies in three sections in South China (Chaohu, Daxiakou, and Zuodeng) and one in northern India (Mud). Our results reveal: 1) recurrent environmental perturbations during the Early Triassic; 2) a general pattern of high terrestrial weathering rates and more intensely reducing marine redox conditions during the early Griesbachian, late Griesbachian, mid-Smithian, and (more weakly) the mid-Spathian; 3) increases in marine productivity during the aforementioned intervals except for the early Griesbachian; and 4) stronger and more temporally discrete intervals of environmental change in deepwater sections (Chaohu and Daxiakou) relative to shallow and intermediate sections (Zuodeng and Mud). Our analysis reveals a close relationship between episodes of marine environmental deterioration and a slowing or reversal of ecosystem recovery based on metrics of biodiversity, within-community (alpha) diversity, infaunal burrowing, and ecosystem tiering. We infer that the pattern and pace of marine ecosystem recovery was strongly modulated by recurrent environmental perturbations during the Early Triassic. These perturbations were associated with elevated weathering and productivity fluxes, implying that nutrient and energy flows were key influences on recovery. More regular secular variation in deepwater relative to shallow-water environmental conditions implies that perturbations originated at depth (i.e., within the oceanic thermocline) and influenced the ocean-surface layer irregularly. Finally, we compared patterns of environmental disturbance and ecosystem recovery following the other four "Big Five" Phanerozoic mass extinctions to evaluate whether commonalities exist. In general, the pace of ecosystem recovery depends on the degree of stability of the post-crisis marine environment. © 2014 Elsevier B.V.


Du G.,University of Wollongong | Guo Z.,University of Wollongong | Wang S.,Hubei University | Zeng R.,University of Wollongong | And 2 more authors.
Chemical Communications | Year: 2010

Restacked MoS2 with enlarged c lattice parameter and surface area was prepared by exfoliation and restacking process, exhibiting high reversible lithium storage capacity and superior rate capability as anode material for lithium ion batteries. © 2010 The Royal Society of Chemistry.


Xiao Z.,Hubei University | Zeng Z.,Hubei University | Komatsu G.,University of Chieti Pescara
Icarus | Year: 2014

The origin of central pit craters on the Moon has long been an enigma, and a primary reason is that their geographic distribution and morphometric characteristics were unknown. We investigated a global inventory of lunar central pit craters using high-resolution image and topography data obtained from the Lunar Reconnaissance Orbiter. 56 certain and 35 probable central pit craters are found on both the lunar maria and highlands. The certain pit craters are ~9-57. km in diameter. The average diameter ratio between the central pits and their parent craters is ~0.12 and the average depth/diameter ratio for the central pits is ~0.072. With irregular-shaped rims, the central pits have conical profiles and some have flat floors. The central pits occur on both crater floors and central peaks. The floor pits are generally larger, deeper, and with more irregular shape compared with summit pits. Both the summit and floor pit craters have formed in every lunar stratigraphic epoch from Nectarian to Copernican. Target properties of background terrains affect the morphology and size of central pits, but they do not determine whether or not a central pit forms during a cratering event. The lunar central pits may have formed by deformation of central peaks caused by some mechanical processes during or soon after the cratering process of their parent craters. © 2013 Elsevier Inc.


Li L.,University of Wollongong | Seng K.H.,University of Wollongong | Feng C.,University of Wollongong | Feng C.,Hubei University | And 3 more authors.
Journal of Materials Chemistry A | Year: 2013

In this work, we synthesize mesoporous and hollow germanium@carbon nanostructures through simultaneous carbon coating and reduction of a hollow ellipsoidal GeO2 precursor. The formation mechanism of GeO 2 ellipsoids and the ratio of Ge4+ to Sn4+ as the starting materials are also investigated. Compared to the solid ellipsoidal Ge@carbon (Ge@C-3), the hollow ellipsoidal Ge@C-1 sample exhibits better cycling stability (100% capacity retention after 200 cycles at the 0.2 C rate) and higher rate capability (805 mA h g-1 at 20 C) compared to Ge@C-3 due to its unique hollow structure; therefore, this hollow ellipsoidal Ge@carbon can be considered as a potential anode material for lithium ion batteries. © 2013 The Royal Society of Chemistry.


Chen Z.,Hubei University | Cao Y.,Pacific Northwest National Laboratory | Qian J.,Hubei University | Ai X.,Hubei University | Yang H.,Hubei University
Journal of Physical Chemistry C | Year: 2010

A simple synthetic route was developed to transform micrometer-sized Sb powders into new Sb-sandwiched nanocomposite particles (SiC-Sb-C) with Sb nanoparticles pinned on rigid SiC nanocores and surfacecoated with carbon by use of a high-energy mechanical milling technique at ambient temperature. The asprepared SiC-Sb-C nanoparticles exhibited excellent cycling ability and rate capability, delivering a specific capacity of >440 mAh g-1 after 120 cycles and a quite high capacity of >220 mAh g-1 at a very high-rate of 4 C (2000 mA g-1). This greatly improved electrochemical performance could be attributed to the structural stability of this material, which can not only effectively confine the volume expansion of the sandwiched Sb layer but also prevent the aggregation of Sb nanocrystallites and keep the mechanical integrity of the electrodes. In addition, this new synthetic method is completely green with a full utilization of raw materials and without any emission of wastes, easily adopted for large-scale production and also extended for other attractive lithium storage metals and alloys. © 2010 American Chemical Society.


Feng Z.,University of Tokyo | Pang J.,University of Tokyo | Pang J.,Hubei University | Kobayashi K.,University of Tokyo | And 2 more authors.
Global Change Biology | Year: 2011

Two modern cultivars [Yangmai16 (Y16) and Yangfumai 2 (Y2)] of winter wheat (Triticum aestivum L.) with almost identical phenology were investigated to determine the impacts of elevated ozone concentration (E-O3) on physiological characters related to photosynthesis under fully open-air field conditions in China. The plants were exposed from the initiation of tillering to final harvest, with E-O3 of 127% of the ambient ozone concentration (A-O3). Measurements of pigments, gas exchange rates, chlorophyll a fluorescence and lipid oxidation were made in three replicated plots throughout flag leaf development. In cultivar Y2, E-O3 significantly accelerated leaf senescence, as indicated by increased lipid oxidation as well as faster declines in pigment amounts and photosynthetic rates. The lower photosynthetic rates were mainly due to nonstomatal factors, e.g. lower maximum carboxylation capacity, electron transport rates and light energy distribution. In cultivar Y16, by contrast, the effects of E-O3 were observed only at the very last stage of flag leaf ageing. Since the two cultivars had almost identical phenology and very similar leaf stomatal conductance before senescence, the greater impacts of E-O3 on cultivars Y2 than Y16 cannot be explained by differential ozone uptake. Our findings will be useful for scientists to select O3-tolerant wheat cultivars against the rising surface [O3] in East and South Asia. © 2010 Blackwell Publishing Ltd.


Wu H.,Hubei University | Wu H.,University of Wollongong | Wexler D.,University of Wollongong | Liu H.,University of Wollongong
Journal of Solid State Electrochemistry | Year: 2011

We report graphene nanosheets as a durable alternative support material for Pt nanoparticle catalysts for oxygen reduction in proton exchange membrane (PEM) fuel cells and compared them to XC-72. The materials were characterized by X-ray diffraction and transmission electron microscopy. Electrochemical surface oxidation of XC-72 and graphene, and of Pt/XC-72 and Pt/graphene has been compared following treatments for up to 120 h. The electrochemical performance of the specimens was evaluated by cyclic voltammetry and linear sweep voltammetry at different surface oxidation time intervals. Electrochemical measurements indicate that the graphene exihibits greatly enhanced electrochemical durability. It is suggested that graphene nanosheet is a promising, low-cost, and durable electrocatalyst support for oxygen reduction in the PEM fuel cell. © 2011 Springer-Verlag.


Wang H.,University of Wollongong | Zhang C.,University of Wollongong | Chen Z.,University of Wollongong | Liu H.K.,University of Wollongong | And 2 more authors.
Carbon | Year: 2015

A novel type of one-dimensional ordered mesoporous carbon fiber has been prepared via the electrospinning technique by using resol as the carbon source and triblock copolymer Pluronic F127 as the template. Sulfur is then encapsulated in this ordered mesoporous carbon fibers by a simple thermal treatment. The interwoven fibrous nanostructure has favorably mechanical stability and can provide an effective conductive network for sulfur and polysulfides during cycling. The ordered mesopores can also restrain the diffusion of long-chain polysulfides. The resulting ordered mesoporous carbon fiber sulfur (OMCF-S) composite with 63% S exhibits high reversible capacity, good capacity retention and enhanced rate capacity when used as cathode in rechargeable lithium-sulfur batteries. The resulting OMCF-S electrode maintains a stable discharge capacity of 690 mAh/g at 0.3 C, even after 300 cycles. © 2014 Elsevier Ltd. All rights reserved.


Chang C.,Hubei University | Zhang L.,Hubei University | Zhou J.,Hubei University | Kennedy J.F.,Advanced Science and Technology Institute
Carbohydrate Polymers | Year: 2010

Hydrogels have been successfully prepared from cellulose in NaOH/urea aqueous solution by using epichlorohydrin (ECH) as a cross-linker, and via heating and freezing methods. Structure and properties of the hydrogels were measured with UV-vis spectroscopy, SEM, XRD, solid-state 13C NMR, rheometry and water absorption testing. The results indicated that hydrogels prepared by heating displayed macroporous inner structure, while fiber-like structure could be observed in the hydrogels prepared by freezing. The light transparency and equilibrium swelling ratio of the hydrogels decreased, while the reswelling water uptake and the storage modulus increased, with an increase of the cellulose content. Compared with the hydrogels post-treated by freezing, the hydrogels prepared by heating displayed better light transmittance, higher equilibrium swelling ratios and reswelling water uptakes, and relatively weaker mechanical strength. Therefore, the structure and properties of the hydrogels could be adjusted by changing the cellulose content and the post-treatment methods. © 2010 Elsevier Ltd. All rights reserved.


Cao Y.,Pacific Northwest National Laboratory | Cao Y.,Hubei University | Xiao L.,Pacific Northwest National Laboratory | Xiao L.,Central China Normal University | And 8 more authors.
Nano Letters | Year: 2012

Hollow carbon nanowires (HCNWs) were prepared through pyrolyzation of a hollow polyaniline nanowire precursor. The HCNWs used as anode material for Na-ion batteries deliver a high reversible capacity of 251 mAh g -1 and 82.2% capacity retention over 400 charge-discharge cycles between 1.2 and 0.01 V (vs Na +/Na) at a constant current of 50 mA g -1 (0.2 C). Excellent cycling stability is also observed at an even higher charge-discharge rate. A high reversible capacity of 149 mAh g -1 also can be obtained at a current rate of 500 mA g -1 (2C). The good Na-ion insertion property is attributed to the short diffusion distance in the HCNWs and the large interlayer distance (0.37 nm) between the graphitic sheets, which agrees with the interlayered distance predicted by theoretical calculations to enable Na-ion insertion in carbon materials. © 2012 American Chemical Society.


Wu H.,Hubei University | Wexler D.,University of Wollongong | Liu H.,University of Wollongong
Materials Chemistry and Physics | Year: 2012

20 wt.% PtNi/C catalysts were prepared using a chemical reduction method, with Vulcan XC-72 conducting furnace black and graphene as the carbon support, respectively, and compared to commercial BASF 20 wt.% Pt/C (using Vulcan XC-72 carbon as support). The materials were characterized by X-ray diffraction, and transmission electron microscopy (TEM). The electrochemical performance of the PtNi/C catalysts was evaluated by cyclic voltammetry, and by steady-state measurements. Electrochemical measurements indicate that the PtNi nanocatalysts exhibited improved activity in the oxygen reduction reaction (ORR) on graphene compared with those on Vulcan XC-72 carbon, and graphene could potentially provide much higher durability than XC-72. This suggests that graphene is a more effective catalyst support than Vulcan XC-72 carbon. © 2012 Elsevier B.V. All rights reserved.


Chen Z.,Hubei University | Cao Y.,Hubei University | Cao Y.,Pacific Northwest National Laboratory | Qian J.,Hubei University | And 2 more authors.
Journal of Materials Chemistry | Year: 2010

A simple synthetic route was developed to obtain Sn-sandwiched composite nanoparticles by mechanical ball-milling ductile Sn particles with rigid SiC nanocores to form a SiC@Sn core-shell nanocomposite and then carbon-coating the SiC@Sn nanoparticles with graphite to produce the SiC@Sn@C nanoparticles. Such a novel nanostructure can effectively buffer the mechanical stress and prevent the aggregation of the Sn nanolayer and therefore improve the electrochemical utilization and cycling stability of electroactive Sn during Li-storage reaction. The Sn-sandwiched nanoparticles as-prepared exhibited a considerable high Li-storage capacity of ∼600 mA h g-1 and an excellent cycling stability with ∼90% capacity retention at 100 cycles, showing a prospect for practical lithium battery applications. In particular, the reported synthetic method is very simple, low-cost and pollution-free, enabling it to be readily adopted for large-scale production and also to be extended for other attractive lithium storage metals and alloys. © 2010 The Royal Society of Chemistry.


Wu H.,Hubei University | Wexler D.,University of Wollongong | Liu H.,University of Wollongong
International Journal of Hydrogen Energy | Year: 2012

The effects of different amounts palladium loading on the hydrogen sorption characteristics of double-walled carbon nanotubes (DWCNTs) have been investigated. The physical properties of the pristine DWCNTs and Pd/DWCNTs were systematically characterized by X-ray diffraction, transmission electron microscopy, and Brunauer-Emmett-Teller surface area measurements. Pd nanoparticles were loaded on DWCNT surfaces for the dissociation of H 2 into atomic hydrogen, which spills over to the defect sites on the DWCNTs. When we use different Pd content, the particle size and dispersion will be different, which affects the hydrogen storage capacity of the DWCNTs. In this work, the hydrogen storage capacities were measured at ambient temperature and found to be 1.7, 1.85, 3.0, and 2.0 wt% for pristine DWCNTS, 1.0 wt%Pd/DWCNTs, 2.0 wt%Pd/DWCNTs, and 3.0 wt%Pd/DWCNTs, respectively. We found that the hydrogen storage capacity can be enhanced by loading with Pd nanoparticles and selecting a suitable content. Furthermore, the sorption can be attributed to the chemical reaction between the atomic hydrogen and the dangling bonds of the DWCNTs. © 2011, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights.


Zhang T.,Hubei University | Zhou K.,Nanjing University of Information Science and Technology | Chen Z.Q.,Hubei University
Physica Status Solidi (B) Basic Research | Year: 2015

Thermoelectric β-Zn4Sb3 samples prepared by spark plasma sintering method have been studied by resistivity measurement, X-ray diffraction (XRD) and positron annihilation spectroscopy (PAS). The existence of Zn vacancies in β-Zn4Sb3 structure is confirmed by PAS, which contribute a positron lifetime component of 212±3 ps. Positron lifetime calculation has been performed for different defect structural models of β-Zn4Sb3. By comparing the calculated lifetime values with the experimental result, we find that each Zn vacancy must have at least two close interstitial Zn atoms in the crystal structure of β-Zn4Sb3. Two separate phase transitions observed by resistivity measurement occur at about 232 and 252 K, whereas the positron annihilation measurements indicate they are about 225 and 240 K. Positron lifetime and Doppler broadening results reveal α' phase is a transition phase between α and β phases. The results also indicate the disordering of interstitial clusters into interstitial Zn sites during the α' to β phase transition. The interstitial Zn clusters are found to act as shallow positron traps which apparently capture positrons below 200 K. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Chen H.,Hubei University | Chen H.,Georgia Regents University | Wu X.,Hubei Maternity and Child Care Hospital | Pan Z.K.,University of Toledo | Huang S.,Georgia Regents University
Cancer Research | Year: 2010

Ovarian cancer is mainly confined in peritoneal cavity and its metastasis is often associated with the formation of malignant ascites. As lysophosphatidic acid (LPA) is present at high levels in ascites of ovarian cancer patients and potently stimulates cell migration, we reason that LPA-stimulated cell migration may play an important role in ovarian cancer metastasis. Here, we show that only ovarian cancer cell lines with LPA migratory response undergo peritoneal metastatic colonization. LPA-stimulated cell migration is required for metastatic colonization because knockdown of LPA receptor subtype 1 (LPAR1) abolishes this event. However, the difference in metastatic potentials is not caused by the absence of LPAR1 because both metastatic and nonmetastatic lines express similar levels of LPAR1. Instead, we find that LPA can activate Rac only in metastatic cells and that metastatic colonization of ovarian cancer cells necessitates Rac activity. These results thus suggest that LPA-induced Rac activation is a prerequisite for ovarian cancer metastasis. In metastatic cells, Rac activation is facilitated by SOS1/EPS8/ABI1 tri-complex and the integrity of this tri-complex is essential for LPAstimulated cell migration and metastatic colonization. We show that at least 1 member of SOS1/EPS8/ABI1 tricomplex is absent in nonmetastatic ovarian cancer cells and reexpressing the missing one conferred them with metastatic capability. Importantly, coexpression of SOS1, EPS8, and ABI1, but not of any individual member of SOS1/EPS8/ABI1 tri-complex, correlates with advanced stages and shorter survival of ovarian cancer patients. Our study implicates that the integrity of SOS1/EPS8/ABI1 tri-complex is a determinant of ovarian cancer metastasis. ©2010 AACR.


Tang X.-L.,Hubei University | Zhou Y.-X.,Hubei University | Wu S.-M.,Hubei University | Wu S.-M.,Wuhan Medical Treatment Center | And 3 more authors.
Journal of Infection | Year: 2014

The development of effective Mycobacterial antigen diagnostic reagents remains a high priority. The 6-kDa early secreted antigenic target (ESAT6) and 10-kDa culture filtrate protein (CFP10) are secreted early by virulent Mycobacterium tuberculosis (M. tb) and are not present in the non-virulent Bacillus Calmette-Guerin (BCG). In this study, we used a Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technique to screen for a functional ssDNA aptamer "antibody" that specifically bound to ESAT6-CFP10 (CE) protein. The selected single ssDNA aptamers (CE24 and CE15) demonstrated the highest specificity and binding affinity to CFP10 (CE24: Kd=3.75×10-7M) and ESAT6 (CE15: Kd=1.6×10-7M). We further detected CFP10 and ESAT6 proteins in serum samples from active pulmonary tuberculosis (TB) patients, extrapulmonary TB patients and healthy donors by using an enzyme-linked oligonucleotide assay (ELONA). The results showed that the sensitivity and specificity were 100% and 94.1% (using CE24 aptamer-based ELONA) and 89.6% and 94.1% (using CE15 aptamer-based ELONA), respectively. A good correlation was observed between aptamer-based ELONA and T-SPOT TB assay. Thus, our study suggests that CE24 and CE15 have potentially broad applications as early antigen diagnostic agents not only for active pulmonary TB, extrapulmonary TB, but also possibly for latent TB infection and TB with immune-deficiency. © 2014 The British Infection Association.


Xiao Z.,Hubei University | Xiao Z.,University of Arizona | Komatsu G.,University of Chieti Pescara
Planetary and Space Science | Year: 2013

Impact craters with ejecta flows and/or central pits have been found on Venus, the Moon, Earth, Mars, and some icy satellites. Using the MESSENGER camera data obtained during the orbital mission, we found craters with ejecta flows and central pits on Mercury. The ejecta flows differ from normal ballistically emplaced ejecta deposits in their long mobilized distances. They all flowed in downslope directions and exhibited a layered morphology. Analog study suggests that the ejecta flows probably have formed by fluidization in the ejecta deposits. Crustal volatiles are not required to form the ejecta flows on Mercury, although they may have helped. The ejecta flows are most likely to be a type of avalanche features in forms of dry granular flows. Central pits in impact craters on Mercury are located on summits of central peaks when viewing in sufficiently high-resolution images, but some of the central pits may occur on crater floors. The central pit craters are all fresh craters located on smooth plains and intercrater plains. The pits are different from the other forms of rimless and irregularly-shaped depressions on Mercury in the size, morphology, and/or occurrence. Crustal volatiles are not required in forming the central pit craters and they may form in a similar way with the central pit craters on the Moon. © 2013 Elsevier B.V. All rights reserved.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: KBBE-2007-3-1-03 | Award Amount: 11.21M | Year: 2008

Replacing fossil oil with renewable resources is perhaps the most urgent need and the most challenging task that human society faces today. Cracking fossil hydrocarbons and building the desired chemicals with advanced organic chemistry usually requires many times more energy than is contained in the final product. Thus, using plant material in the chemical industry does not only replace the fossil material contained in the final product but also save substantial energy in the processing. Of particular interest are seed oils which show a great variation in their composition between different plant species. Many of the oil qualities found in wild species would be very attractive for the chemical industry if they could be obtained at moderate costs in bulk quantities and with a secure supply. Genetic engineering of vegetable oil qualities in high yielding oil crops could in a relatively short time frame yield such products. This project aims at developing such added value oils in dedicated industrial oil crops mainly in form of various wax esters particularly suited for lubrication. This project brings together the most prominent scientists in plant lipid biotechnology in an unprecedented world-wide effort in order to produce added value oils in industrial oil crops within the time frame of four years as well as develop a tool box of genes und understanding of lipid cellular metabolism in order for rational designing of vast array of industrial oil qualities in oil crops. Since GM technologies that will be used in the project are met with great scepticism in Europe it is crucial that ideas, expectations and results are communicated to the public and that methods, ethics, risks and risk assessment are open for debate. The keywords of our communication strategies will be openness and an understanding of public concerns.


Liu Y.,Guangdong University of Finance | Luo S.,Guangdong University of Finance | Ye Y.,Hubei University
Computers and Mathematics with Applications | Year: 2013

This paper is concerned with the blow-up of the solution to a parabolic problem with a gradient nonlinearity under nonlinear boundary conditions. Lower bound for blow-up time is derived when the blow-up does occur. © 2013 Elsevier Ltd. All rights reserved.


Xie Y.,Eastern Michigan University | Sha Z.,Hubei University | Bai Y.,CAS Institute of Botany
ISPRS Journal of Photogrammetry and Remote Sensing | Year: 2010

Large and growing archives of orbital imagery of the earth's surface collected over the past 40 years provide an important resource for documenting past and current land cover and environmental changes. However uses of these data are limited by the lack of coincident ground information with which either to establish discrete land cover classes or to assess the accuracy of their identification. Herein is proposed an easy-to-use model, the Tempo-Spatial Feature Evolution (T-SFE) model, designed to improve land cover classification using historical remotely sensed data and ground cover maps obtained at later times. This model intersects (1) a map of spectral classes (S-classes) of an initial time derived from the standard unsupervised ISODATA classifier with (2) a reference map of ground cover types (G-types) of a subsequent time to generate (3) a target map of overlaid patches of S-classes and G-types. This model employs the rules of Count Majority Evaluation, and Subtotal Area Evaluation that are formulated on the basis of spatial feature evolution over time to quantify spatial evolutions between the S-classes and G-types on the target map. This model then applies these quantities to assign G-types to S-classes to classify the historical images. The model is illustrated with the classification of grassland vegetation types for a basin in Inner Mongolia using 1985 Landsat TM data and 2004 vegetation map. The classification accuracy was assessed through two tests: a small set of ground sampling data in 1985, and an extracted vegetation map from the national vegetation cover data (NVCD) over the study area in 1988. Our results show that a 1985 image classification was achieved using this method with an overall accuracy of 80.6%. However, the classification accuracy depends on a proper calibration of several parameters used in the model. © 2009 International Society for Photogrammetry and Remote Sensing, Inc. (ISPRS).


Gao Y.,Hubei University | Liu H.W.,Hubei University | Lin Y.,Hubei University | Shao G.,University of Bolton
Thin Solid Films | Year: 2011

A novel PV cell structure in the form of a p-i-n construction is proposed by inserting a layer of FeSi2 between two layers of crystalline silicon. The energy band diagram and PV properties are simulated. The structure parameters, such as the thickness, doping concentration and defect density of states of each layer, are taken into account. The optimized structure with a thickness less than 1 μm shows a large open circuit voltage (Voc) of 0.68 V and a high photoelectric conversion efficiency (Eff) of 24.7%, which is significantly larger than that of the FeSi2/Si double-layer pn-heterojunction structure, and is comparable with the performance of crystalline Si solar cells with a thickness of 250 μm. The Voc and Eff increase further when replacing the crystalline Si at both sides of the FeSi2 layer with amorphous Si layers. The present work is expected to open a new avenue in developing low-cost thin film solar cells on the basis of the well established Si technology. © 2011 Elsevier B.V. All rights reserved.


Yang Y.,Hubei University | Hou Z.-C.,China Agricultural University | Qian Y.-H.,Hubei University | Kang H.,Hubei University | Zeng Q.-T.,Hubei University
Molecular Phylogenetics and Evolution | Year: 2012

Previous phylogenetic analyses of the melanogaster species group have led to conflicting hypotheses concerning their relationship; therefore the addition of new sequence data is necessary to discover the phylogeny of this species group. Here we present new data derived from 17 genes and representing 48 species to reconstruct the phylogeny of the melanogaster group. A variety of statistical tests, as well as maximum likelihood mapping analysis, were performed to estimate data quality, suggesting that all genes had a high degree of contribution to resolve the phylogeny. Individual locus was analyzed using maximum likelihood (ML), and the concatenated dataset (12,988. bp) were analyzed using partitioned maximum likelihood (ML) and Bayesian analyses. Separated analysis produced various phylogenetic relationships, however, phylogenetic topologies from ML and Bayesian analysis based on concatenated dataset, at the subgroup level, were completely identical to each other with high levels of support. Our results recovered three major clades: the ananassae subgroup, followed by the montium subgroup, the melanogaster subgroup and the oriental subgroups form the third monophyletic clade, in which melanogaster (takahashii, suzukii) forms one subclade and ficusphila [. eugracilis (elegans, rhopaloa)] forms another. However, more data are necessary to determine the phylogenetic position of Drosophila lucipennis which proved difficult to place. © 2011 Elsevier Inc.


Feng Y.,University of Minnesota | Feng Y.,Hubei University | Zhang X.,University of Minnesota | Graves P.,New York Medical College | Zeng Y.,University of Minnesota
RNA | Year: 2012

Dicer cleaves double-stranded RNAs (dsRNAs) or precursor microRNAs (pre-miRNAs) to yield ∼22-nt RNA duplexes. The pre-miRNA structure requirement for human Dicer activity is incompletely understood. By large-scale in vitro dicing assays and mutagenesis studies, we showed that human Dicer cleaves most, although not all, of the 161 tested human pre-miRNAs efficiently. The stable association of RNAs with Dicer, as examined by gel shift assays, appears important but is not sufficient for cleavage. Human Dicer tolerates remarkable structural variation in its pre-miRNA substrates, although the dsRNA feature in the stem region and the 2-nt 3′-overhang structure in a pre-miRNA contribute to its binding and cleavage by Dicer, and a large terminal loop further enhances pre-miRNA cleavage. Dicer binding protects the terminal loop from digestion by S1 nuclease, suggesting that Dicer interacts directly with the terminal loop region. Copyright © 2012 RNA Society.


Ding Q.,CAS Institut Pasteur of Shanghai | Cao X.,CAS Institut Pasteur of Shanghai | Lu J.,CAS Institut Pasteur of Shanghai | Huang B.,CAS Institut Pasteur of Shanghai | And 5 more authors.
Journal of Hepatology | Year: 2013

Background & Aims Hepatitis C virus (HCV) is a major human viral pathogen that causes chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. In most cases, acute HCV infection becomes persistent, at least in part due to viral evasion of host innate immune response. Although HCV genomic RNA contains pathogen-associated molecular pattern (PAMP) that is able to induce host interferon responses, HCV can shut down the responses by using the viral NS3/4A protease to cleave MAVS/VISA and TRIF, two key adaptor molecules essential for the interferon signaling activation. The aim of this study was to explore a novel NS3/4A-independent mechanism HCV utilizes to evade host innate immune responses. Methods We used the interferon promoter-reporter system to screen HCV encoded proteins for their activities to suppress the interferon signaling and to determine the molecular targets of viral proteins. Co-immunoprecipitation, confocal microscopy, and siRNA-based gene silencing were used to investigate the molecular mechanism. Results We found that, in addition to NS3/4A, NS4B can suppress double-stranded RNA or RNA virus induced interferon activation. NS4B interacts with STING/MITA, an important molecule that mediates the HCV PAMP induced interferon signaling. Mechanistic studies indicated that NS4B disrupts the interactions between STING/MITA and TBK1. Conclusions In conclusion, we reported an additional mechanism for HCV evasion of host interferon responses in which viral NS4B protein targets STING/MITA to suppress the interferon signaling. Our results present important evidence for the control of interferon response by HCV, and shed more light on the molecular mechanisms underlying the persistence of HCV infection. © 2013 European Association for the Study of the Liver. Published.


Xu J.,CAS Institute of Genetics and Developmental Biology | Wang W.,Qinghai Normal University | Yin H.,Qinghai Normal University | Liu X.,CAS Institute of Genetics and Developmental Biology | And 2 more authors.
Plant and Soil | Year: 2010

The effects of nitric oxide (NO) on cadmium toxicity in Medicago truncatula seedlings were studied by investigating root growth and uptake of antioxidants, IAA and ions. Exposure to cadmium reduced root growth and NO accumulation, and increased the production of reactive oxygen species (ROS) in roots. Supplementation with NO improved root growth and reduced ROS accumulation in roots. The NO-scavenger cPTIO, the nitrate reductase (NR) inhibitor tungstate, and the NO synthase (NOS) inhibitor L-NAME all inhibited the accumulation of NO in roots and reversed the effects of NO in promoting the root growth and accumulation of proline and glutathione. Application of NO reduced auxin degradation by inhibiting the activity of IAA oxidase. Exogenous NO also enhanced the uptake of K + and Ca 2+. These results suggest that NO improves cadmium tolerance in plants by reducing oxidative damage, maintaining the auxin equilibrium and enhancing ion absorption. © Springer Science + Business Media B.V. 2009.


Kong X.,Peking Union Medical College | Wang R.,Peking Union Medical College | Xue Y.,Hubei University | Liu X.,Peking Union Medical College | And 4 more authors.
PLoS ONE | Year: 2010

Background: Sirtuin 3 (SIRT3) is one of the seven mammalian sirtuins, which are homologs of the yeast Sir2 gene. SIRT3 is the only sirtuin with a reported association with the human life span. Peroxisome proliferator-activated receptor c coactivator-1a (PGC-1a) plays important roles in adaptive thermogenesis, gluconeogenesis, mitochondrial biogenesis and respiration. PGC-1a induces several key reactive oxygen species (ROS)-detoxifying enzymes, but the molecular mechanism underlying this is not well understood. & Results: Here we show that PGC-1a strongly stimulated mouse Sirt3 gene expression in muscle cells and hepatocytes. Knockdown of PGC-1a led to decreased Sirt3 gene expression. PGC-1a activated the mouse SIRT3 promoter, which was mediated by an estrogen-related receptor (ERR) binding element (ERRE) (2407/2399) mapped to the promoter region. Chromatin immunoprecipitation and electrophoretic mobility shift assays confirmed that ERRa bound to the identified ERRE and PGC-1a co-localized with ERRa in the mSirt3 promoter. Knockdown of ERRa reduced the induction of Sirt3 by PGC-1a in C2C12 myotubes. Furthermore, Sirt3 was essential for PGC-1a-dependent induction of ROS-detoxifying enzymes and several components of the respiratory chain, including glutathione peroxidase-1, superoxide dismutase 2, ATP synthase 5c, and cytochrome c. Overexpression of SIRT3 or PGC-1a in C2C12 myotubes decreased basal ROS level. In contrast, knockdown of mSIRT3 increased basal ROS level and blocked the inhibitory effect of PGC-1a on cellular ROS production. Finally, SIRT3 stimulated mitochondrial biogenesis, and SIRT3 knockdown decreased the stimulatory effect of PGC-1a on mitochondrial biogenesis in C2C12 myotubes. & Conclusion: Our results indicate that Sirt3 functions as a downstream target gene of PGC-1a and mediates the PGC-1a effects on cellular ROS production and mitochondrial biogenesis. Thus, SIRT3 integrates cellular energy metabolism and ROS generation. The elucidation of the molecular mechanisms of SIRT3 regulation and its physiological functions may provide a novel target for treating ROS-related disease. © 2010 Kong et al.


Zhang X.,Hubei University | Gunzburger M.,Florida State University | Ju L.,University of South Carolina | Ju L.,Beijing Computational Science Research Center
Computer Methods in Applied Mechanics and Engineering | Year: 2016

In this paper, we study nodal-type quadrature rules for approximating hypersingular integrals and their applications to numerical solution of finite-part integral equations and nonlocal diffusion problems. We first derive explicit expressions for the quadrature coefficients and establish corresponding error estimates. Some collocation schemes are then constructed based on these rules to numerically solve certain type of finite-part integral equations and nonlocal diffusion problems in one dimension, and condition number and optimal error estimates for the proposed schemes are also rigorously obtained. On uniform grids, these schemes are of Toeplitz structure which results in many advantages in developing fast linear solvers. Various numerical experiments are also performed to illustrate the theoretical results. © 2015 Elsevier B.V.


Macroporous pH-sensitive graphene oxide (GO)/poly(acrylic acid-co-acrylamide) (PAA) nanocomposite hydrogels were prepared by frontal polymerization (FP) using a solvent mixture composed of DMF and a small quantity of GO water solution as a heat conductive medium. A flat frontal can be obtained. The high temperature on the propagating front evaporated water to produce many vapor bubbles, which were trapped into the hydrogel matrix and consequently formed a macroporous structure (i.e. diameter ca. 120 μm). The increase in the concentration of GO solution led to an increase in front velocity (Vf) and the highest front temperature (Tmax). Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) indicated that GO nanosheets were crosslinked into the PAA hydrogel. Scanning electron microscope (SEM) analysis illustrated that the size of pores in GO/PAA nanocomposite hydrogels highly depended on the concentration of GO solution. The macroporous structure of nanocomposite hydrogels had a significant influence on the pH-sensitive swelling behaviors of the nanocomposite hydrogels. The highest compressive strength of the GO/PAA nanocomposite hydrogel can reach 44.9 MPa. © The Royal Society of Chemistry 2016.


Pan F.,Hubei University | Wu X.,Wuhan University of Technology
Procedia Engineering | Year: 2011

The purpose of this thesis is to discuss the sustainable development of high-rise building in Chinese cities. As the construction climax of high-rise building has arrived in China, many constructed or constructing high-rise buildings are still in the state of environment-unfriendly, low standard and efficiency, high consumption and pollution, and featureless. This kind of development is not sustainable. The method used in this study is analysis of environment protection, safety, and efficiency of the high-rise building, which tend to solve these above problems and make a sustainable development. The paper suggests that it is necessary to establish the green high-rise building system, which to be composed of external environment, internal floorplan and Architectural Form. © 2011 Published by Elsevier Ltd.


Fan C.,Hubei University | Liao L.,Hubei University | Zhang C.,Sun Yat Sen University | Liu L.,Hubei University
Journal of Materials Chemistry B | Year: 2013

To develop hydrogels with high mechanical strength for cell encapsulation and three-dimensional culture is a critical challenge for cartilage tissue engineering. In this study, novel double network (DN) hydrogels were fabricated and phosphate buffer solution (PBS) was used as the solvent to facilitate cell encapsulation. The tough DN hydrogels were prepared through a two-step photopolymerization using neutral oligo(2,2-dimethyltrimethylene carbonate)-poly(ethylene glycol)-oligo(2,2-dimethyltrimethylene carbonate)-diacrylate (DPD-DA) chains for the first network and methacrylated hyaluronic acid (HA-GMA) chains for the second network. The fracture stress values of the optimized and cell-laden DN hydrogels were 8.38 ± 0.67 MPa and 6.28 ± 1.26 MPa, respectively, which showed comparable mechanical strength with natural articular cartilage tissue. The live/dead cell viability assay of cell-laden DN hydrogels demonstrated the tough DN hydrogels have comparable cytocompatibility with PEG hydrogels. After long-term culture, cartilage-specific extra cellular matrix accumulated in these DN hydrogels. The results indicated the potential of the novel DN hydrogels as cartilage tissue engineering scaffolds. This journal is © The Royal Society of Chemistry 2013.


Yang F.J.,Tohoku University | Yang F.J.,Hubei University | Sakuraba Y.,Tohoku University | Kokado S.,University of Shizuoka | And 3 more authors.
Physical Review B - Condensed Matter and Materials Physics | Year: 2012

The anisotropic magnetoresistance (AMR) effect was systematically investigated in epitaxially grown Co 2Fe xMn 1-xSi films against Fe composition x and the annealing temperature. A change of sign in the AMR ratio from negative to positive was clearly detected when x increased from 0.6 to 0.8. This sign reversal can reasonably be explained by the change in the dominant s-d scattering process from s →d to s →d caused by the creation of large d-states at the Fermi level, suggesting the disappearance of half-metallicity at x = 0.8. The variations in the remanent density of states in the half-metallic gap against annealing temperature are also discussed from the viewpoint of the AMR ratio on the basis of the s-d scattering model. © 2012 American Physical Society.


Xu X.,Hubei University | Huang J.,Hubei University | Li J.,Xiamen University | Yan J.,Xiamen University | And 2 more authors.
Chemical Communications | Year: 2011

Graphene oxide (GO) was found to effectively enhance the selectivity of aggregation-induced emission (AIE) biosensors, and a new method based on GO and AIE molecules was proposed to detect bovine serum albumin (BSA) with high sensitivity and selectivity. © 2011 The Royal Society of Chemistry.


Joachimski M.M.,Friedrich - Alexander - University, Erlangen - Nuremberg | Lai X.,Hubei University | Shen S.,CAS Nanjing Institute of Geology and Palaeontology | Jiang H.,Hubei University | And 4 more authors.
Geology | Year: 2012

High-resolution oxygen isotope records document the timing and magnitude of global warming across the Permian-Triassic (P-Tr) boundary. Oxygen isotope ratios measured on phosphate-bound oxygen in conodont apatite from the Meishan and Shangsi sections (South China) decrease by 2‰ in the latest Permian, translating into low-latitude surface water warming of 8 °C. The oxygen isotope shift coincides with the negative shift in carbon isotope ratios of carbonates, suggesting that the addition of isotopically light carbon to the ocean-atmosphere system by Siberian Traps volcanism and related processes resulted in higher greenhouse gas levels and global warming. The major temperature rise started immediately before the main extinction phase, with maximum and harmful temperatures documented in the latest Permian (Meishan: bed 27). The coincidence of climate warming and the main pulse of extinction suggest that global warming was one of the causes of the collapse of the marine and terrestrial ecosystems. In addition, very warm climate conditions in the Early Triassic may have played a major role in the delayed recovery in the aftermath of the Permian-Triassic crisis.


Dan W.,CAS Institute of Geology and Geophysics | Dan W.,University of Chinese Academy of Sciences | Li X.-H.,CAS Institute of Geology and Geophysics | Li X.-H.,Hubei University | And 4 more authors.
Gondwana Research | Year: 2012

The Alxa Block is the westernmost part of the North China Craton (NCC). In the past, it has been considered to be part of the Archean NCC. However, formation and evolution of this block remain poorly understood, and this has hampered a broader understanding of the NCC. In this study we analyzed the in situ zircon U-Pb age and Hf-O isotopes for the two oldest rock units in the eastern Alxa Block, namely the Bayanwulashan and Diebusige Complexes. The Bayanwulashan Complex consists mainly of metamorphic rocks with mafic and felsic protoliths. SIMS U-Pb zircon dating results indicate that the primary magmatic ages of the mafic and felsic igneous rocks are ca. 2.34Ga and ca. 2.32-2.30Ga, respectively, and both sets of rocks were overprinted by two metamorphic events at ca. 1.89Ga and ca. 1.79Ga. Geochemical and zircon Hf-O isotopic data suggest that the ca. 2.34Ga amphibolites within the Bayanwulashan Complex are characteristically high in TiO 2 (up to 3.2%), Zr (up to 394ppm) and Ti/V (>30), resembling the basaltic rocks formed within continental rifts. The ca. 2.32-2.30Ga felsic rocks were generated by remelting of dominant meta-igneous rocks that have zircon Hf model ages of 2.92-2.81Ga. The Diebusige Complex is composed of amphibolites, mafic gneisses and paragneisses. It was intruded by granites dated at ca. 1.97-1.98Ga, and subjected to high grade metamorphic events at ca. 1.89Ga and ca. 1.79Ga. Re-examination of U-Pb ages for detrital and metamorphic zircons indicate that the depositional ages of protoliths of the Diebusige paragneisses may be considered to be between ca. 2.45 and 2.0Ga. These U-Pb zircon age data do not support the existence of exposed Archean rocks in the eastern Alxa Block, although the possibility of Archean rocks at deeper crustal levels cannot be ruled out entirely.The eastern Alxa Block contrasts to the neighboring Yinshan Block and Khondlite Belt, as well as the Trans-North China Orogen, in terms of the timing and evolution of magmatism and metamorphism. Thus, we conclude that the Alxa Block is a separated Paleoproterozoic terrane from the Western Block of the NCC, rather than the western extension of the Yinshan Block or part of the Khondalite Belt, as previously proposed. © 2011 International Association for Gondwana Research.


Wang G.,Hubei University | Huang B.,Hubei University | Xiao L.,Hubei University | Ren Z.,Hubei University | And 5 more authors.
Journal of the American Chemical Society | Year: 2014

The dependence on Pt catalysts has been a major issue of proton-exchange membrane (PEM) fuel cells. Strategies to maximize the Pt utilization in catalysts include two main approaches: to put Pt atoms only at the catalyst surface and to further enhance the surface-specific catalytic activity (SA) of Pt. Thus far there has been no practical design that combines these two features into one single catalyst. Here we report a combined computational and experimental study on the design and implementation of Pt-skin catalysts with significantly improved SA toward the oxygen reduction reaction (ORR). Through screening, using density functional theory (DFT) calculations, a Pt-skin structure on AuCu(111) substrate, consisting of 1.5 monolayers of Pt, is found to have an appropriately weakened oxygen affinity, in comparison to that on Pt(111), which would be ideal for ORR catalysis. Such a structure is then realized by substituting the Cu atoms in three surface layers of AuCu intermetallic nanoparticles (AuCu iNPs) with Pt. The resulting Pt-skinned catalyst (denoted as PtSAuCu iNPs) has been characterized in depth using synchrotron XRD, XPS, HRTEM, and HAADF-STEM/EDX, such that the Pt-skin structure is unambiguously identified. The thickness of the Pt skin was determined to be less than two atomic layers. Finally the catalytic activity of PtSAuCu iNPs toward the ORR was measured via rotating disk electrode (RDE) voltammetry through which it was established that the SA was more than 2 times that of a commercial Pt/C catalyst. Taking into account the ultralow Pt loading in PtSAuCu iNPs, the mass-specific catalytic activity (MA) was determined to be 0.56 A/mgPt@0.9 V, a value that is well beyond the DOE 2017 target for ORR catalysts (0.44 A/mgPt@0.9 V). These findings provide a strategic design and a realizable approach to high-performance and Pt-efficient catalysts for fuel cells. © 2014 American Chemical Society.


Shen J.,CAS Shanghai Institutes for Biological Sciences | Li Y.,Huazhong University of Science and Technology | Li Y.,Hubei University | Gu H.,Hubei University | And 2 more authors.
Chemical Reviews | Year: 2014

The detection of proteins, nucleic acids, small molecules, and ions is of great importance in both the study of their fundamental functions and the development of molecular diagnostics. These biological molecules and ions not only are involved in the construction of living organisms, but also carry out most biological functions, including storage and transmission of genetic information, regulating biochemical activities and reactions, storing and transporting energy, and providing mechanical support. With the development of biotechnology, different recognition molecules, such as antibodies, oligonucleotide sequences, and aptamers, have been applied to specifically and selectively recognize protein, DNA, small molecules, and ions. At the same time, the feasibility of modifying the antibody with different signaling markers, such as fluorescein, radionuclides, enzymes, and redox tags, in turn allows for a broader variety of readouts in a sandwich-structured assay.


Hu S.,Hubei University | Cheng Q.,Wuhan University | Cheng Q.,York University | Wang L.,State University of New York at Buffalo | Xu D.,Wuhan University
Landscape and Urban Planning | Year: 2013

Characterizing the spatial distribution of urban land price is essential for improving urban planning and management, as well as for effectively modeling and predicting changes in urban land use. Previous studies have shown that in using conventional geostatistics methods to characterize the local structure of land price, there is controversy regarding the effectiveness of interpolation. In this paper, a recently developed Multifractal Inverse Distance Weighted (MIDW) interpolation method is applied to characterize the spatial structure of land price, and a spectrum analysis method (S- A) based on a fractal filtering technique is applied to separate the singularity from the background of land price distribution; these methods are applied to a study site in the city of Wuhan (China). It is shown that the MIDW interpolation method is a valid and effective alternative for characterizing land price distribution by comparison with ordinary IDW and Kriging methods. Based on deviation and parameters, the results of the MIDW method not only fit better with the surveyed values, but they also incorporate both the singularity and spatial association in data interpolation. The singularity of land price, which could be attributed to local special landscapes, such as the Yangtze River and East Lake, was successfully separated from its background by the S- A method. The background, which represents the overall spatial trend of land price distribution, was reclassified by the fractal concentration-area method. The derived singularity and background will better aid the decision-making process for urban planning. © 2012.


Guo Z.,University of Namur | Guo Z.,Hubei University | Liu W.,CAS Lanzhou Institute of Chemical Physics | Su B.-L.,University of Namur | Su B.-L.,Wuhan University of Technology
Journal of Colloid and Interface Science | Year: 2011

Nature is the creation of aesthetic functional systems, in which many natural materials have vagarious structures. Inspired from nature, such as lotus leaf, butterfly' wings, showing excellent superhydrophobicity, scientists have recently fabricated a lot of biomimetic superhydrophobic surfaces by virtue of various smart and easy routes. Whilst, many examples, such as lotus effect, clearly tell us that biomimicry is dissimilar to a simple copying or duplicating of biological structures. In this feature article, we review the recent studies in both natural superhydrophobic surfaces and biomimetic superhydrophobic surfaces, and highlight some of the recent advances in the last four years, including the various smart routes to construct rough surfaces, and a lot of chemical modifications which lead to superhydrophobicity. We also review their functions and applications to date. Finally, the promising routes from biomimetic superhydrophobic surfaces in the next are proposed. © 2010 Elsevier Inc.


Sun L.,Wuhan University of Technology | Wu W.,Hubei University | Yang S.,Central South University | Zhou J.,Wuhan University of Technology | And 4 more authors.
ACS Applied Materials and Interfaces | Year: 2014

Our study reports a novel iron oxide/noble metal/semiconductor ternary multilayer hybrid structure that was synthesized through template synthesis and layer-by-layer deposition. Three different morphologies of α-Fe 2O3/Ag/SiO2/SnO2 hybrid architectures were obtained with different thicknesses of the SiO2 interlayer which was introduced for tailoring and controlling the coupling of noble metal Ag nanoparticles (NPs) with the SnO2 semiconductor. The resulting samples were characterized in terms of morphology, composition, and optical property by various analytical techniques. The as-obtained α-Fe2O3/Ag/SiO2/SnO2 nanocomposites exhibit enhanced visible light or UV photocatalytic abilities, remarkably superior to commercial pure SnO2 products, bare α-Fe2O3 seeds, and α-Fe2O 3/SnO2 nanocomposites. Moreover, the sample of α-Fe2O3/Ag/SiO2/SnO2 also exhibits good chemical stability and recyclability because it has higher photocatalytic activity even after eight cycles. The origin of enhanced photocatalytic activity on the multilayer core-shell α-Fe 2O3/Ag/SiO2/SnO2 nanocomposites was primarily ascribed to the coupling between noble metal Ag and the two semiconductors Fe2O3 and SnO2, which are proven to be applied in recyclable photocatalysis. © 2013 American Chemical Society.


Chen Y.,Hubei University | Zeng S.,Hubei University | Qian J.,Hubei University | Wang Y.,Wuhan University of Technology | And 3 more authors.
ACS Applied Materials and Interfaces | Year: 2014

Si has been considered as a promising alternative anode for next-generation lithium ion batteries (LIBs), but the commercial application of Si anodes is still limited due to their poor cyclability. In this paper, we propose a new strategy to enhance the long-term cyclability of Si anode by embedding nano-Si particles into a Li+-conductive polymer to form a Si/polymer composite with core-shell structure, in which nano-Si cores act as active Li-storage phase and the polymeric matrix serves not only as a strong buffer to accommodate the volume change, but also as a protection barrier to prevent the direct contact of Si surface with electrolyte, so as to maintain the mechanical integrity of Si anode and suppress the repeated destruction and construction of solid electrolyte interphase (SEI) on the Si surface. To realize this strategy, we synthesize a Si/PPP (polyparaphenylene) composite simply by ball-milling the Si nanoparticles with PPP polymer that has n-doping activity. Our experimental results demonstrate that the thus-prepared Si/PPP composite exhibits a high capacity of 3184 mA h g-1 with an initial coulombic efficiency of 78%, an excellent rate capability with a considerably high capacity of 1670 mA h g-1 even at a very high rate of 16 A g-1, and a long-term cyclability with 60% capacity retention over 400 cycles, showing a great prospect for battery application. In addition, this structural design could be adopted to other Li-storable metals or alloys for developing cycle-stable anode materials for Li-ion batteries. © 2014 American Chemical Society.


Shen J.,Hubei University | Algeo T.J.,University of Cincinnati | Zhou L.,Hubei University | Feng Q.,Hubei University | And 2 more authors.
Geobiology | Year: 2012

The Dongpan section in southern Guangxi Province records the influence of local volcanic activity on marine sedimentation at intermediate water depths (~200-500m) in the Nanpanjiang Basin (South China) during the late Permian crisis. We analyzed ~100 samples over a 12-m-thick interval, generating palynological, paleobiological, and geochemical datasets to investigate the nature and causes of environmental changes. The section records at least two major volcanic episodes that culminated in deposition of approximately 25- to 35-cm-thick ash layers (bentonites) and that had profound effects on conditions in both the Dongpan marine environment and adjacent land areas. Intensification of eruptive activity during each volcanic cycle resulted in a shift toward conifer forests, increased wildfire intensity, and elevated subaerial weathering fluxes. The resulting increase in nutrient fluxes stimulated marine productivity in the short term but led to a negative feedback on productivity in the longer term as the OMZ of the Nanpanjiang Basin expanded, putting both phytoplankton and zooplankton communities under severe stress. Radiolarians exhibit large declines in diversity and abundance well before the global mass extinction horizon, demonstrating the diachroneity of the marine biotic crisis. The latest Permian crisis, which was probably triggered by the Siberian Traps flood basalts, intensified the destructive effects of the earlier local eruptions on terrestrial and marine ecosystems of the South China craton. © 2011 Blackwell Publishing Ltd.


Ou L.,University of Science and Arts of Iran | Ou L.,Hubei University | Chen S.,Hubei University
Journal of Physical Chemistry C | Year: 2013

DFT geometry optimization and minimum energy path calculations were used to investigate the mechanisms of oxygen reduction reaction (ORR) on the Pd(111) and Pt(111) surfaces, including the adsorption and dissociation of O2 molecule and the protonation of dissociated adsorbates. The results indicated that in the presence of a hydrated proton ORR on the Pd(111) surface proceeded through the adsorption and dissociation of O2 molecule, whereas ORR on the Pt(111) surface may involve in parallel the adsorption and dissociation of O2 molecule as well as the formation and dissociation of OOH species. During the entire four-electron ORR, the protonation of adsorbed O atom to form OH is the rate-determining step (rds) on both of the Pd(111) and Pt(111) surfaces. Such a finding about the rds of ORR can well explain why Pt- and Pd-based catalysts that more weakly bind atomic oxygen have better ORR activity. Comparison of the ORR mechanisms on the Pd(111) and Pt(111) surfaces revealed that the adsorption and dissociation processes of O2 molecule more easily occurred on the Pt(111) surface and that the serial protonation of the dissociative product to form H2O molecule also more easily occurred on the Pt(111) surface than on the Pd(111) surface. Therefore, the difference between the catalytic activities for ORR between both metals was large, explaining why Pt can serve as ORR electrocatalysts and the inexpensive Pd cannot. © 2013 American Chemical Society.


Yang F.J.,Hubei University | Yang F.J.,Tohoku University | Wei C.,Hubei University | Chen X.Q.,Hubei University
Applied Physics Letters | Year: 2013

In this paper, the anisotropic magnetoresistance (AMR) effect was investigated to check the half-metallic/non-half-metallic nature of epitaxial Co2FeSi films. The evolution of the microstructure shows that the B2 and L21-ordering of Co2FeSi films will increase with increasing annealing temperature which causes a decrease of the d-states in the down-spin channel. When Co2FeSi films are annealed at 650 °C, better B2 and L21-ordering will change the dominant s-d scattering from s↑→d↓ to s↑→d↑. The change from a non-half-metallic to a half-metallic nature of the Co2FeSi films induces a sign change of the AMR ratio from positive to negative and a small value of the Gilbert constant (α 0.0022). © 2013 AIP Publishing LLC.


Fan C.,Hubei University | Zhang C.,Sun Yat Sen University | Jing Y.,Sun Yat Sen University | Liao L.,Hubei University | Liu L.,Hubei University
RSC Advances | Year: 2013

A series of biodegradable hydrogels based on oligo(2,2-dimethyltrimethylene carbonate)-block-poly(ethylene glycol)-block-oligo(2,2-dimethyltrimethylene carbonate) diacrylate (DPD-DA) precursor with varied length of hydrophilic poly(ethylene glycol) (PEG) segment and hydrophobic oligo(2,2- dimethyltrimethylene carbonate) (ODTC) segment were prepared by photopolymerization. Hydrophobic interaction was found to affect the properties of the hydrogel. The elastic modulus and toughness of the hydrogel could be tuned by altering the lengths of the hydrophobic ODTC segment as well as the hydrophilic PEG segment. In a monolayer culture, the number of swine cartilage chondrocytes (SCCs) attached to the hydrogel surface increased along with an increase in the length of ODTC segment in the precursor. SCCs cultured on the surface of hydrogel and photo-encapsulated in the hydrogel demonstrated comparable cytocompatibility with the widely recognized PEG hydrogel. This journal is © The Royal Society of Chemistry.


Wang Y.,Hubei University | Wang Y.,Guizhou University | Xu J.,Hubei University | Li J.,Hubei University | Wu F.,Hubei University
Journal of Hazardous Materials | Year: 2013

Photooxidation of arsenite(As(III)) in a suspension of natural montmorillonite under the irradiation of metal halide lamp (λ≥313nm)has been investigated. The results showed that the natural montmorillonite induced the photooxidation of As(III) by generating hydroxyl radicals (HO) and hydroperoxyl/superoxide radicals (HO2/O2 -). HO which was responsible for the As(III) photooxidation. Approximately 38% of HO was generated by the photolysis of ferric ions, and the formation of the remaining 62% was strongly dependent on the HO2/O2 -. The presence of free ironions (Fe2+ and Fe3+), made significant contributions to the photogeneration of these reactive oxygen species (ROS). The photooxidation of As(III) in natural montmorillonite suspensions was greatly influenced by the pH values. The photooxidation of As(III) by natural montmorillonite followed the Langmuir-Hinshelwood equation. In addition, the photooxidation of As(III) could be enhanced by the addition of humic acid. This work demonstrates that photooxidation may be an important environmental process for the oxidation of As(III) and may be a way to remove As(III) from acidic surface water containing iron-bearing clay minerals. © 2013 Elsevier B.V.


Zhang N.,Wuhan University of Technology | Deng Y.,Wuhan University of Technology | Tai Q.,Wuhan University of Technology | Cheng B.,Hubei University | And 10 more authors.
Advanced Materials | Year: 2012

A nanostructured platform that combines electrospun TiO 2 nanofibers (TiNFs)-deposited substrate and cell-capture agent realizes significant capture of circulating tumor cells (CTCs). The enhanced local topographic interactions between the horizontally packed TiNFs deposited substrates and extracellular matrix scaffolds, in addition to anti-EpCAM/EpCAM biological recognition, contributes to the significantly enhanced capture efficiency compared to flat surfaces. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Yu J.,Wuhan University of Technology | Fan J.,Wuhan University of Technology | Zhao L.,Wuhan University of Technology | Zhao L.,Hubei University
Electrochimica Acta | Year: 2010

Dye-sensitized solar cells (DSSCs) are fabricated based on hollow anatase TiO2 (HA-TiO2) spheres synthesized by a chemically induced self-transformation (CIST) strategy using urea as a base catalyst, whose walls are composed of anatase nanocrystals and exhibit hierarchical porosity. TiO2 hollow structured materials not only have low density, high specific surface areas, and hierarchically porous structures, but also exhibit high light-collection efficiency and fast motion of charge carriers. Effects of calcination temperatures on the performance of HA-TiO2 solar cells are investigated and discussed. With increasing calcination temperatures, the light-electricity conversion efficiencies (η) increase. At 600 °C, HA-TiO2 cells reach the highest efficiency. The performances of HA-TiO2 cells are also compared with Degussa P-25 (P25) TiO2 nanoparticle cells at the same film thickness, and their optimal efficiencies at 600 °C are 4.82 and 4.35%, respectively. The enhanced performance of HA-TiO2 cells is due to their high surface area and hierarchically nanoporous structures when compared with the nonporous TiO2 nanoparticles (P25). © 2009 Elsevier Ltd. All rights reserved.


Jin L.,Wuhan University of Technology | Wu Y.,Hubei University
Journal of Molecular Recognition | Year: 2011

δ-Dendrotoxin, isolated from mamba snake venom, has 57 residues cross-linked by three disulfide bridges. The protein shares a pharmacological activity with other animal toxins, the potent blockade of potassium channels, but is structurally unrelated to toxins of different species. We employed alanine-scanning mutagenesis to explore the molecular mechanism of δ-dendrotoxin binding to potassium channels, using protein-protein docking and molecular dynamic simulations. In our reasonable model of the δ-dendrotoxin-ShaKv1.1 complex, δ-dendrotoxin interacted mainly with the N-terminal region and the turn of two antiparallel β-sheets of the channel. This binding mode could well explain the functional roles of critical residues in δ-dendrotoxin and the ShaKv1.1 channel. Structural analysis indicated that the critical Lys6 residue of δ-dendrotoxin plugged its side chain into a channel selectivity filter. Another two critical δ-dendrotoxin residues, Lys3 and Arg10, were found to contact channel residues through strong polar and nonpolar interactions, especially salt-bridge interactions. As for the ShaKv1.1 channel, the channel turrets were found in the "half-open state," and two of four Glu423 in the turrets of the channel B and D chains could interact, respectively, with Lys3 and Lys26 of δ-dendrotoxin through electrostatic interactions. The essential Asp431 channel residue was found to associate electrostatically with Arg10 of δ-dendrotoxin, and a critical Tyr449 channel residue was just under the channel-interacting surface of δ-dendrotoxin. Together, these novel data may accelerate the structure-function research of toxins in the dendrotoxin family and be of significant value in revealing the diverse interactions between animal toxins and potassium channels. Copyright © 2010 John Wiley & Sons, Ltd.


Chen B.,Friedrich - Alexander - University, Erlangen - Nuremberg | Joachimski M.M.,Friedrich - Alexander - University, Erlangen - Nuremberg | Shen S.-Z.,CAS Nanjing Institute of Geology and Palaeontology | Lambert L.L.,University of Texas at San Antonio | And 4 more authors.
Gondwana Research | Year: 2013

A high-resolution oxygen isotope record based on 356 measurements of conodont apatite from several low latitudinal sections in South China, USA and Iran was composed in order to unravel Permian palaeotemperature and ice volume history. The conodont apatite δ18O record is compared to published brachiopod calcite δ18O records. Brachiopods and conodonts from different palaeocontinents show significantly different δ18O values, suggesting differences in local climatic conditions (e.g., evaporation/precipitation ratio). As a consequence, secular changes in palaeotemperature and oxygen isotope composition of Permian sea water cannot be reconstructed from records combined from different areas, but have to be based on records from a specific area.Oxygen isotope analyses of different conodont taxa suggest that Streptognathodus and Hindeodus lived in near-surface seawater and recorded surface water temperature, whereas the habitat of gondolellid genera was variable depending on sea level, with both near-surface and deeper waters as potential life habitat. The oxygen isotope record measured on conodonts from South China exhibits relative high values between 22 and 23‰ VSMOW during the glaciated Early Permian, translating into warm seawater temperature between 26 and 30°C, assuming that the Late Palaeozoic ice volumes were comparable to the Pleistocene glacial maxima. In contrast to the earlier view that the Late Palaeozoic Ice Age (LPIA) terminated in the late Sakmarian, the South China conodont apatite oxygen isotope record suggests waning of the ice sheets in the Kungurian. Ice melting is indicated by a pronounced decrease in δ18O of 2‰ VSMOW, which is interpreted as reflecting the combined effect of climatic warming and glacial ice melting. Significant temperature fluctuations (4°C warming succeeded by 6 to 8°C cooling) are observed during the Guadalupian-Lopingian transition, interpreted as combined climate changes induced by Emeishan volcanism and changes in habitat depth of gondolellid conodonts. Oxygen isotope values increase to 22‰ VSMOW in the Changhsingian, which suggests climate cooling and Clarkina moving to deeper waters because of the Changhsingian sea level rise. Across the Permian-Triassic boundary, δ18O values decrease from 22 to 19‰ VSMOW, parallel to the significant negative carbon isotope excursion and the eruption of the Siberian Traps. The latter is pointing to a cause-effect relationship as a consequence of the massive release of volcanic greenhouse gases derived from the Siberian volcanism and related processes. © 2012 International Association for Gondwana Research.


Ma D.-Z.,Hubei University | Wu J.-P.,Bohai University | Zhang J.,Bohai University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2014

By the Poincare sections, the dynamical behaviors of the ring string in the anti-de Sitter-Gauss-Bonnet black hole are studied. A threshold value of the Gauss-Bonnet parameter λ is found by the numerical method, below which the behavior of this dynamical system is nonchaotic and above which the behavior becomes gradually chaotic. The chaotic behavior becomes stronger with the increases of the Gauss-Bonnet parameter. It is different from the case in the anti-de Sitter-Schwarzschild black hole, which is weakly chaotic. Furthermore, we confirm our findings by the fast Lyapunov indicator. © 2014 American Physical Society.


Harada Y.,Hubei University | Goossens S.,University of Maryland Baltimore County | Matsumoto K.,Japan National Astronomical Observatory | Yan J.,Hubei Engineering University | And 3 more authors.
Nature Geoscience | Year: 2014

Tidal heating of a solid planetary body occurs by viscous dissipation, depending on its internal structure and thermal and orbital states. Calculations of the response of the Moon to tidal forces have considered lunar interior structure, but have not reproduced the geodetically observed dependence of dissipation on the lunar tidal period. The attenuation of seismic waves in the deep lunar interior is expected to be consistent with a low-viscosity layer at the core-mantle boundary, which may explain the observed frequency dependence. Here we numerically simulate the viscoelastic tidal response of a Moon that contains a low-viscosity layer at the core-mantle boundary and compare with geodetic observations. In our simulations, a layer with a viscosity of about 2 × 1016 Pa s leads to frequency-dependent tidal dissipation that matches tidal dissipation measurements at both monthly and annual periods. Compared with the lunar asthenosphere, the calculated viscosity is extremely low, and suggests partial melting at the lunar core-mantle boundary. We also find that tidal dissipation is not evenly distributed in the lunar interior, but localized within the low-viscosity layer, which implies that this layer may act as a thermal blanket on the lunar core and influence the Moon's thermal evolution. © 2014 Macmillan Publishers Limited.


Tse Y.-L.S.,James Franck Institute | Chen C.,James Franck Institute | Chen C.,Hubei University | Lindberg G.E.,Northern Arizona University | And 2 more authors.
Journal of the American Chemical Society | Year: 2015

Significant effort has been undertaken to better understand the molecular details governing the propensity of ions for the air-water interface. Facilitated by computationally efficient reactive molecular dynamics simulations, new and statistically conclusive molecular-scale results on the affinity of the hydrated excess proton and hydroxide anion for the air-water interface are presented. These simulations capture the dynamic bond breaking and formation processes (charge defect delocalization) that are important for correctly describing the solvation and transport of these complex species. The excess proton is found to be attracted to the interface, which is correlated with a favorable enthalpic contribution and consistent with reducing the disruption in the hydrogen bond network caused by the ion complex. However, a recent refinement of the underlying reactive potential energy function for the hydrated excess proton shows the interfacial attraction to be weaker, albeit nonzero, a result that is consistent with the experimental surface tension measurements. The influence of a weak hydrogen bond donated from water to the protonated oxygen, recently found to play an important role in excess hydrated proton transport in bulk water, is seen to also be important for this study. In contrast, the hydroxide ion is found to be repelled from the air-water interface. This repulsion is characterized by a reduction of the energetically favorable ion-water interactions, which creates an enthalpic penalty as the ion approaches the interface. Finally, we find that the fluctuation in the coordination number around water sheds new light on the observed entropic trends for both ions. © 2015 American Chemical Society.


Ni B.,University of California at Los Angeles | Shprits Y.,University of California at Los Angeles | Hartinger M.,University of California at Los Angeles | Angelopoulos V.,University of California at Los Angeles | And 2 more authors.
Journal of Geophysical Research: Space Physics | Year: 2011

In this study we perform an energy channel dependent cross-satellite calibration of Time History of Events and Macroscale Interactions during Substorms (THEMIS) solid state telescope (SST) flux measurements based on electron phase space density (PSD) conjunctions at fixed phase space coordinates. By comparing PSD around L* = 6 between THEMIS SST and Los Alamos National Laboratory (LANL) satellite LANL-01A synchronous orbit particle analyzer (SOPA) for a half year period starting from 1 July 2007, we evaluate systematic errors in the THEMIS SST measurements and quantify the cross-instrument calibration factors for the 11 SST energy channels from 40 to 2159 keV. Good consistency in electron PSD conjunctions between the five THEMIS probes indicates that the SST instrument aboard each spacecraft responds quite similarly to the ambient electron radiation environment. Compared to the LANL-01A SOPA instrument, the THEMIS SST underestimates the electron fluxes within a factor of 2 for the 40-140 keV energy channels and overestimates the electron fluxes within a factor of 3 for the 204-2159 keV energy channels. Using the cross-satellite calibrated SST flux data for the five THEMIS spacecraft and the SOPA measurements from the LANL-01A and 1989-048 satellites, we analyze the response of radiation belt electrons to a sudden solar wind pressure enhancement event. The electron PSD conjunctions between the THEMIS probes and the two geostationary satellites show good agreement, suggesting a reasonable cross-satellite calibration of the SST measurements. Our results also indicate a clear correlation between electron PSD dropouts and the solar wind pressure pulse, which is likely due to the combination of magnetopause shadowing and outward radial diffusion. The gradual buildup of electron PSD after the abrupt pressure enhancement most likely results from a combined effect of local acceleration and inward and outward radial diffusion that refills the main phase PSD dropout when the magnetopause moves outward. A longer-term quantitative analysis of the temporal evolution and radial profile of electron PSD based on multiple satellite measurements, including the cross-satellite calibrated THEMIS SST data, will be required to improve our understanding of the dynamic responses of radiation belt electrons to solar activity. Copyright 2011 by the American Geophysical Union.


Zhou D.,Hubei University | Lu X.,Hubei University | Xu J.,CAS Wuhan Institute of Physics and Mathematics | Yu A.,Hubei University | And 3 more authors.
Chemistry of Materials | Year: 2012

Dry gel conversion (DGC) technique is first applied in the synthesis of organic-inorganic hybrid aluminosilicate zeolites. By using the DGC method, methylene-bridged organic-inorganic hybrid zeolites with an MOR topology are synthesized without organic additive, which are structurally characterized by powder XRD, FTIR, solid-state 29Si, 13C, 27Al MAS NMR, SEM, elemental analysis, XRF, XPS, and N 2 adsorption techniques. This work first reports that thus-synthesized methylene-bridged hybrid zeolites can be successfully bestowed with excellent catalytic activities through different modification treatments. Co 2+-exchanged hybrid zeolites are applied in the epoxidation of alkenes with air to achieve good conversions and selectivities. Especially, methylene-bridged hybrid zeolites can be sulfonated with fuming sulfuric acid to form acidic MOR-SO 3H catalyst, which exhibits highly catalytic activity for the acid-catalyzed condensation reaction of cyclohexanone and glycol. This method will be one potential route for the fabrication of organic-inorganic hybrid zeolite or related molecular sieve catalysts. © 2012 American Chemical Society.


Zheng Y.-L.,Hubei University | Li Y.-X.,Wuhan University | Lei D.-M.,Wuhan University of Technology
International Journal of Advanced Manufacturing Technology | Year: 2012

This paper considered fuzzy flexible job scheduling problems with makespan and maximum machine workload and proposed a multi-objective swarm-based neighborhood search (MOSNS). In MOSNS, ordered operation-based doublet string and three-dimension array are used to indicate the solution of two subproblems, two swaps and an insertion are applied to produce new solutions, simple weighted objective-based methods are used to update swarm and external archive to obtain a set of nondominated solutions. Some numerical experiments are conducted by using some instances and computational results show that MOSNS performs better than the existing methods from literature. © 2011 Springer-Verlag.


Xia X.,Hubei Engineering University | Wang Q.,Xinjiang Normal University | Li Y.,Hubei University
International Journal of Modelling, Identification and Control | Year: 2013

A novel quantum genetic algorithm based on cellular automata (CA) is proposed called cellular automata model quantum genetic algorithm (CA-QGA). In CA-QGA, each individual in population is mapped to a cell in CA, and the evolutionary of population is realised by the cells" iteration based on a function. Under the guidance of the function, some helpful information in each excellent individual can spread out across the whole population through much iteration. Aimed to maintain the diversity of population and help algorithm jump out of a local optimal solution, a quantum catastrophe is adopted when the best individual no longer improves. It is proved that this algorithm has lower time complexity and can converge to a global optimal solution with probability 1. Experimental results illustrate that the proposed algorithm has better performance. © 2013 Inderscience Enterprises Ltd.


Wang A.,Wuhan University of Technology | Wang A.,Hubei University | Wang W.,Wuhan University of Technology | Long C.,Wuhan University of Technology | And 4 more authors.
Journal of Materials Chemistry C | Year: 2014

An easy and flexible two-step approach consisting of annealing and subsequently selective pitting corrosion has been developed to prepare porous carbonyl iron flakes (CIFs). Based on the dependence of the morphologies and compositions of the resultant CIFs on the annealing temperature and corrosion time, a formation mechanism for the porous CIFs has been substantiated. In our protocol, the annealing process carried out as the first step in the formation process causes an increase in the grain size and forces the Fe nanocrystals to react with the N impurities in the raw CIFs to generate dispersed Fe 4N domains. These domains subsequently induce selective pitting corrosion, resulting in porous CIFs. As a result of the porous structure, the as-obtained porous CIFs have a specific surface area of 16.92 m2 g-1, a saturation magnetization of 140 emu g-1 and a coercivity of 61 Oe. Compared with the raw CIFs, they have a large permeability at high frequencies and a modest permittivity. Consequently, composites containing 20 vol% of the porous CIFs in paraffin wax display a reflection loss ≤-20 dB over a wide frequency range of 2.9-20 GHz when the thickness is varied between 0.9 and 4.5 mm. The results reported here suggest a facile approach to preparing porous nanocrystalline metals. Our results offer a promising strategy for the fabrication of absorbents for thin-thickness and strong-absorption microwave absorbing materials with working frequencies adjustable over a wide range simply by varying the thickness. © 2014 the Partner Organisations.


Wu F.-X.,University of Saskatchewan | Wu L.,University of Saskatchewan | Wang J.,Central South University | Liu J.,Hubei University | And 2 more authors.
Scientific Reports | Year: 2014

We have often observed unexpected state transitions of complex systems. We are thus interested in how to steer a complex system from an unexpected state to a desired state. Here we introduce the concept of transittability of complex networks, and derive a new sufficient and necessary condition for state transittability which can be efficiently verified. We define the steering kernel as a minimal set of steering nodes to which control signals must directly be applied for transition between two specific states of a network, and propose a graph-theoretic algorithm to identify the steering kernel of a network for transition between two specific states. We applied our algorithm to 27 real complex networks, finding that sizes of steering kernels required for transittability are much less than those for complete controllability. Furthermore, applications to regulatory biomolecular networks not only validated our method but also identified the steering kernel for their phenotype transitions.


Fan X.,CAS Beijing National Laboratory for Molecular | Cui C.,CAS Beijing National Laboratory for Molecular | Fang G.,Wuhan University | Wang J.,Hubei University | And 4 more authors.
Advanced Functional Materials | Year: 2012

Polymer solar cells (PSCs) with poly(3-hexylthiophene) (P3HT) as a donor, an indene-C 70 bisadduct (IC 70BA) as an acceptor, a layer of indium tin oxide modified by MoO 3 as a positive electrode, and Ca/Al as a negative electrode are presented. The photovoltaic performance of the PSCs was optimized by controlling spin-coating time (solvent annealing time) and thermal annealing, and the effect of the spin-coating times on absorption spectra, X-ray diffraction patterns, and transmission electron microscopy images of P3HT/IC 70BA blend films were systematically investigated. Optimized PSCs were obtained from P3HT/IC 70BA (1:1, w/w), which exhibited a high power conversion efficiency of 6.68%. The excellent performance of the PSCs is attributed to the higher crystallinity of P3HT and better a donor-acceptor interpenetrating network of the active layer prepared under the optimized conditions. In addition, PSCs with a poly(3,4-ethylenedioxy-thiophene) :poly(styrenesulfonate) (PEDOT:PSS) buffer layer under the same optimized conditions showed a PCE of 6.20%. The results indicate that the MoO 3 buffer layer in the PSCs based on P3HT/IC 70BA is superior to that of the PEDOT:PSS buffer layer, not only showing a higher device stability but also resulting in a better photovoltaic performance of the PSCs. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Shu S.,Hubei University | Li J.,Hua Zhong Normal University
Physical Review C - Nuclear Physics | Year: 2010

The Friedberg-Lee (FL) model is studied at finite temperature and density. The soliton solutions of the FL model in the deconfinement phase transition are solved and thoroughly discussed for certain boundary conditions. We indicate that the solitons before and after the deconfinement have different physical meanings: the soliton before deconfinement represents hadrons, while the soliton after the deconfinement represents the bound state of quarks which leads to a strongly interacting quark-gluon plasma phase. The corresponding phase diagram is given. © 2010 The American Physical Society.


Zheng X.,Rutgers University | Cao B.,Rutgers University | Liu T.-L.,Hubei University | Zhang X.,Rutgers University | Zhang X.,Hubei University
Advanced Synthesis and Catalysis | Year: 2013

The high enantioselective rhodium-catalyzed hydroformylation of 1,1-disubstituted allylphthalimides has been developed. By employing chiral ligand 1,2-bis[(2S,5S)-2,5-diphenylphospholano]ethane [(S,S)-Ph-BPE], a series of β3-aminoaldehydes can be prepared with up to 95% enantioselectivity. This asymmetric procedure provides an efficient alternative route to prepare chiral β3-amino acids and alcohols. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Wang J.,University of Houston | Zhang K.-Y.,Daye Peoples Hospital | Liu S.-M.,Hubei University | Sen S.,University of Houston
Molecules | Year: 2014

MicroRNAs (miRNAs), the 17- to 25-nucleotide long noncoding RNAs that modulate the expression of mRNAs and proteins, have emerged as critical players in cancer initiation and progression processes. Deregulation of tissue miRNA expression levels associated with specific genetic alterations has been demonstrated in cancer, where miRNAs function either as oncogenes or as tumor-suppressor genes and are shed from cancer cells into circulation. The present review summarizes and evaluates recent advances in our understanding of the characteristics of tumor tissue miRNAs, circulating miRNAs, and the stability of miRNAs in tissues and their varying expression profiles in circulating tumor cells, and body fluids including blood plasma. These advances in knowledge have led to intense efforts towards discovery and validation of differentially expressing tumorassociated miRNAs as biomarkers and therapeutic targets of cancer. The development of tumor-specific miRNA signatures as cancer biomarkers detectable in malignant cells and body fluids should help with early detection and more effective therapeutic intervention for individual patients. © 2014 by the authors; licensee MDPI, Basel, Switzerland.


Gao S.,Hubei University | Gui X.-E.,Hubei University | Liang K.,Hubei University | Liu Z.,Shuqu Hospital | And 2 more authors.
AIDS Research and Human Retroviruses | Year: 2012

In this study, one hundred and three HIV-positive Chinese Han patients treated with a nevirapine (NVP)-based regimens were investigated for the association between nevirapine hypersensitivity reaction (NVP HSR) and human leukocyte antigen (HLA) allele. HLA-Cw, -DRB1 alleles were determined in 32 NVP HSR cases and 71 NVP-tolerant patients. We found that considerable overlap was observed for the clinical and demographic characteristics of the 32 hypersensitive patients and 71 tolerant patients. Twelve out of 32 NVP HSR cases developed allergic hepatotoxicity. More HLA-Cw*04 alleles were observed in NVP HSR cases than in NVP-tolerant cases (p=0.029). The frequency of HLA-DRB1*15 in NVP-tolerant cases was significant higher than that in NVP HSR cases ( p=0.018). Multivariate logistic regression identified that HLA-Cw*04 presence was a risk factor related to NVP HSR (p=0.030, OR=3.611, 95% CI of OR: 1.135-11.489). To clearly understanding its value in clinical practice, further studies involving larger cohorts of patients from different races with different levels of immune suppression are needed. © Copyright 2012, Mary Ann Liebert, Inc.


Ge X.,Central China Normal University | Asiri A.M.,King Abdulaziz University | Du D.,Central China Normal University | Du D.,Washington State University | And 3 more authors.
TrAC - Trends in Analytical Chemistry | Year: 2014

Nanomaterial-enhanced paper-based biosensors, including lateral-flow test-strip (LFTS), and paper microfluidic devices, provide powerful analytical platforms for the development of affordable, portable, low-cost technologies for point-of-care and in-field assays. By combining with different kinds of nanoparticles (NPs), the nanomaterial-based LFTS and paper microfluidic devices are showing great potential in enhancing detection sensitivity and selectivity. In this review, we provide a general overview of paper-based biosensing techniques, in which various NPs are involved, especially applications in biomedical and environmental studies. The first part provides detailed examples in LFTSs, while the second part gives a brief overview of paper microfluidics. Nanomaterial-enhanced paper-based biosensors could be used in physicians' office laboratories, nursing homes, hospitals, and the home. They may also make a great impact in global health in diagnosing health conditions in developing countries. © 2014 Elsevier Ltd.


Wu Q.,Hubei University | Meng X.,Central China Normal University | Zhong C.,Hubei University | Chen X.,Hubei University | Qin J.,Hubei University
Journal of the American Chemical Society | Year: 2014

This paper describes the synthesis, crystal structure, and photophysical properties of a new compound Rb2CdBr2I2. It crystallizes in the noncentrosymmetric space group Ama2. In the crystal, all the distorted tetrahedron [CdBr2I2]2- groups are arranged in a way such that all the Cd-I bonds are located in the same side of the Cd atoms resulting in a net polarization. Rb2CdBr 2I2 showed a powder second harmonic generation (SHG) response 4 times that of KH2PO4 (KDP). The preliminary measurement indicated that it exhibits a large laser-induced damage threshold (LDT) of 190 MW/cm2 which is 6 times that of AgGaS2. It also exhibits a wide transparent region (0.37-14 μm) with a relatively high (up to 490 °C) thermal stability. All these indicate that Rb 2CdBr2I2 is a new promising candidate for NLO materials in the IR region. © 2014 American Chemical Society.


Fang Y.,Hubei University | Xiao L.,Central China Normal University | Qian J.,Hubei University | Ai X.,Hubei University | And 2 more authors.
Nano Letters | Year: 2014

FePO4 nanospheres are synthesized successfully through a simple chemically induced precipitation method. The nanospheres present a mesoporous amorphous structure. Electrochemical experiments show that the FePO 4/C electrode demonstrates a high initial discharging capacity of 151 mAh g-1 at 20 mA g-1, stable cyclablilty (94% capacity retention ratio over 160 cycles), as well as high rate capability (44 mAh g -1 at 1000 mA g-1) for Na-ion storage. The superior electrochemical performance of the FePO4/C nanocomposite is due to its particular mesoporous amorphous structure and close contact with the carbon framework, which significantly improve the ionic and electronic transport and intercalation kinetics of Na ions. © 2014 American Chemical Society.


Tian T.,Xiangtan University | Wang X.F.,Xiangtan University | Li W.,Hubei University
Solid State Communications | Year: 2013

As high-temperature structural materials, L12 intermetallic compounds have attracted the strong interest from both fundamental and industrial aspects. Understanding of elastic property is a basis for the complete investigations of mechanical behavior of L12 alloys. In an effort to explore the electronic origin of elastic properties of L12 intermetallics, we have performed a systematic study on elastic constants for single crystals, and Young's modulus, shear modulus, bulk modulus and Poisson's ratio for poly-crystals of 22 known Al3X and X3Al-type (X=transition or main group metal) intermetallics using the ab initio calculations. Based on the calculations of elastic constants and extreme (both positive and negative) Poisson's ratios, we found a pronounced correlation between the extreme Poisson's ratio and the elastic anisotropy, i.e., approximate 40% of the investigated L12 intermetallics exhibit intrinsic auxetic behavior. Furthermore, based on the distribution of bonding charge densities, we revealed that the ductility and extreme Poisson's ratios were attributable to the directionality of bonds of these alloys. Our findings provide a new method to predict mechanical behavior of intermetallics. © 2012 Elsevier Ltd.


Liu M.,Central China Normal University | Nie Y.,Central China Normal University | Yu J.,Hubei University
Shengtai Xuebao/ Acta Ecologica Sinica | Year: 2012

Soil infiltration is the basic hydrological process for water penetrating into the soil, and the amount of water infiltrating the soil surface directly affects the quantity of surface runoff and soil erosion, even the recharge of both soil and underground water. The initial soil water content is an important factor to soil infiltration, and its role in runoff controlling and soil erosion prevention has been taken into account by many researches. In this study, the double-ring infiltration method was used to quantitatively measure the infiltrability of surface soil (0-5 cm depth) covered with forestland and grassland, which were under two antecedent soil water contents of 12% and 40%, respectively. In addition, the changes of soil infiltration process over time were estimated with different infiltration models. The results indicated that the initial soil infiltration rate of forestland and grassland tended to decrease with increasing initial soil water content. And an increase in initial soil water content results in an increase in steady infiltration rate and cumulative infiltration rate. Whether forestland or grassland, soil infiltration process with higher initial soil water content reaches the steady infiltration stage earlier than that with lower initial soil water content. For forestland with initial soil gravimetric water content rate of 12%, the initial soil infiltration rate was 8.95 mm/min, which was four times to the initial infiltration rate for forestland soil with gravimetric water content rate of 40%. However, its steady infiltration rate 0.24 mm/min was only one eighth of the forestland with initial soil gravimetric water content rate of 40%, and the cumulative infiltration in an hour was only two thirds of that. This phenomena may attribute to the faster wetting rate of drier soil in infiltration process, which cause stronger slaking forces of the soil and severe aggregates breakdown, enhance surface sealing or promote the destruction of soil structure, and then significantly decrease the soil infiltrability. For grassland surface soil with ample organic matter, soil infiltrability and infiltration process suggested lower sensitivity to initial soil water content. Initial infiltration rate, steady infiltration rate, and one hour cumulative infiltration of grassland with 12% soil water content were 2.21 mm/ min, 0.62 mm/min, 59.16 mm, respectively. And these parameters of grassland with 41% soil water content were 2.07 mm/min, 1.7 mm/min, 110.27 mm, which suggested less significant difference than that of forestland. Whether covered with forestland or grassland, soil instant infiltration rate decreased rapidly at the beginning of the infiltration process, and then decreased approximately linearly with time until approached to constant, especially under the condition of the initial soil water content to be 12%. The least square method was used to simulate the infiltration rate changes with time, and the results indicated that soil infiltration process of forestland and grassland were all fitted better by Horton and Kostiakov infiltration models than by Philip infiltration model. Besides, Horton infiltration model was the best model to describe soil infiltration process, which made it suitable to describe the soil infiltration process of forestland and grassland in the Three Gorges Reservoir area.


Lili L.,Central China Normal University | Xu H.,Central China Normal University | Song D.,Central China Normal University | Cui Y.,Central China Normal University | And 2 more authors.
Journal of Chromatography A | Year: 2010

A new dispersive liquid-liquid microextraction based on solidification of floating organic droplet method (DLLME-SFO) was developed for the determination of volatile aldehyde biomarkers (hexanal and heptanal) in human blood samples. In the derivatization and extraction procedure, 2,4-dinitrophenylhydrazine (DNPH) as derivatization reagent and formic acid as catalyzer were injected into the sample solution for derivatization with aldehydes, then the formed hydrazones was rapidly extracted by dispersive liquid-liquid microextraction with 1-dodecanol as extraction solvent. After centrifugation, the floated droplet was solidified in an ice bath and was easily removed for analysis. The effects of various experimental parameters on derivatization and extraction conditions were studied, such as the kind and volume of extraction solvent and dispersive solvent, the amount of derivatization reagent, derivatization temperature and time, extraction time and salt effect. The limit of detections (LODs) for hexanal and heptanal were 7.90 and 2.34nmolL-1, respectively. Good reproducibility and recovery of the method were also obtained. The proposed method is an alternative approach to the quantification of volatile aldehyde biomarkers in complex biological samples, being more rapid and simpler and providing higher sensitivity compared with the traditional dispersive liquid-liquid microextraction (DLLME) methods. © 2010 Elsevier B.V.


Fang Y.,Hubei University | Xiao L.,Central China Normal University | Ai X.,Hubei University | Cao Y.,Hubei University | Yang H.,Hubei University
Advanced Materials | Year: 2015

Hierarchical carbon framework wrapped Na3V2(PO4)3 (HCF-NVP) is successfully synthesized through chemical vapor deposition on pure Na3V2(PO4)3 particles. Electrochemical experiments show that the HCF-NVP electrode can deliver a large reversible capacity (115 mA h g-1 at 0.2 C), superior high-rate rate capability (38 mA h g-1 at 500 C), and ultra-long cycling stability (54% capacity retention after 20 000 cycles). © 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.


Ye W.,Qingdao University | Lu C.,Qingdao University | You P.,Qingdao University | Liang K.,Hubei University | Zhou Y.,Xiangtan University
Journal of Applied Crystallography | Year: 2013

In recent years, inconsistent space groups of monoclinic B1a1 and orthorhombic B2cb have been reported for the room-temperature ferroelectric phases of both Bi4Ti3O12 and lanthanide-substituted Bi4Ti3O12. In this article, the electron diffraction technique is employed to unambiguously clarify the crystal symmetries of ferroelectric Bi4Ti3O12 and Bi3.15Nd0.85Ti3O12 single crystals at room temperature. All the reflections observed from the two crystals match well with those derived from B1a1, but the observed reflections 010, 030, 10 and 30 should be forbidden in the case of B2cb. This fact indicates that both the ferroelectrics are of the space group B1a1 rather than B2cb, which is confirmed by convergent-beam electron diffraction observations. On the basis of the monoclinic space group B1a1, the lattice parameters of both the ferroelectrics were calculated by the Rietveld refinement of powder X-ray diffraction data. © 2013 International Union of Crystallography.


Jianming L.,State Grid Corporation of China | Bingzhen Z.,Hubei University
CCIS2011 - Proceedings: 2011 IEEE International Conference on Cloud Computing and Intelligence Systems | Year: 2011

Energy and information are two important parts of utility services. Smart grid applies the information and communications technology in the energy industry which will bring new methods and techniques for the application of the renewable energy, smart home and other smart services. By using Optical Fiber Composite Low-voltage Cable (OPLC), Power Fiber to the Home (PFTTH) realizes the transmission of energy and information over the same cable which will bring about the multipurpose use of resources. Therefore, PFTTH is the top choice for constructing the smart grid utilization network integrating energy industry and information industry which will not only meet the requirements of electric power supply of smart grid, but also meet the diversity requirements of the users including service providers and residential customers, such as leasing the optical fiber resources to the telecom operator and serving the 'triple play' to the residential customers. The PFTTH constructs a multi-utility services platform and the scope of the smart power consumption will be extended that both energy and information services can be provided simultaneously based on this platform. This paper describes the PFTTH's key technologies and its applications in the construction of smart grid, and then introduces the capability and the application scenario of the constructed platform. Finally, further open issues of the future development of PFTTH and the constructed platform are presented. © 2011 IEEE.


Hu G.,Wenzhou University | Hu G.,University of Northern British Columbia | Li J.,Wenzhou University | Li J.,University of Northern British Columbia | Hou H.,Hubei University
Journal of Hazardous Materials | Year: 2015

A combination of solvent extraction and freeze thaw was examined for recovering oil from the high-moisture petroleum refinery wastewater treatment pond sludge. Five solvents including cyclohexane (CHX), dichloromethane (DCM), methyl ethyl ketone (MEK), ethyl acetate (EA), and 2-propanol (2-Pro) were examined. It was found that these solvents except 2-Pro showed a promising oil recovery rate of about 40%, but the recycling of DCM solvent after oil extraction was quite low. Three solvents (CHX, MEK and EA) were then selected for examining the effect of freeze/thaw treatment on improving the quality of recovered oil. This treatment increased the total petroleum hydrocarbon (TPH) content in recovered oil from about 40% to 60% for both MEK and EA extractions, but little effect was observed for CHX extraction. Although the solid residue after oil recovery had a significantly decreased TPH content, a high concentration of heavy metals was observed, indicating that this residue may require proper management. In general, the combination of solvent extraction with freeze/thaw is effective for high-moisture oily hazardous waste treatment. © 2014 Elsevier B.V.


Eaton D.A.R.,University of Chicago | Fenster C.B.,University of Maryland University College | Hereford J.,University of Maryland University College | Huang S.-Q.,Hubei University | Ree R.H.,Field Museum of Natural History
Ecology | Year: 2012

A pervasive hypothesis at the interface of ecology and evolution is that biotic interactions contribute to regional biodiversity by accelerating adaptation and speciation. We investigated this question in the context of closely related, bumble bee-pollinated plants (Pedicularis spp.) in the Hengduan Mountains of south-central China, where they exhibit spectacular levels of richness, endemism, and floral diversity. Because these species co-occur frequently, flower synchronously, and share pollinators during the brief reproductive season, we predict that pollinator-mediated interactions may influence their community assembly and evolutionary diversification. If disparity in floral traits reduces competitive interactions between species, as would happen if floral isolation mitigates reproductive interference caused by heterospecific pollen flow, then species with dissimilar flowers should co-occur more often, yielding greater floral diversity at local scales than expected by chance. Moreover, if such interactions have repeatedly driven character displacement, then floral traits should exhibit homoplasy, the phylogenetic signature of labile evolution. We present evidence supporting these predictions, and find that local species richness is best explained by a model including both floral diversity and phylogenetic distance. Our results suggest that a dynamic mosaic of pollinator-mediated interactions among Pedicularis in the Hengduan region promotes ecological sorting through recurrent selection against reproductive interference, causing rapid species turnover at local scales, and accelerating the rate of floral divergence among species. Together these processes may have contributed to the remarkable accumulation of florally diverse species of Pedicularis endemic to the Hengduan Mountains biodiversity hotspot. © 2012 by the Ecological Society of America.


Sun Y.,Hubei University | Wang N.,University of Science and Technology of China | Guo X.,Harbin Institute of Technology | Peng Z.,East China University of Science and Technology
Journal of Electronic Commerce Research | Year: 2013

The advancement of mobile technology and the increasing importance of health promote the boom in mobile health services (MHS) around the world. Although there have been several studies investigating the health technology acceptance behavior from a variety of theoretical perspectives, they have not provided a unified understanding. To fill this research gap, this paper: (1) reviews the health technology acceptance literature and discusses three prominent models (e.g., the technology acceptance model, the theory of planned behavior or the unified theory of use and acceptance of technology, and the protection motivation theory), (2) empirically compares the three models, and (3) formulates and empirically validates the unified model in the context of mobile health services. In the unified model of health technology acceptance, we propose that users' intention to use mobile health services is determined by five key factors: performance expectancy, effort expectancy, social influence, facilitating conditions, and threat appraisals. The results show that the unified model outperforms the three alternative models by significantly improving the R-squares. Finally, the implications for theory and practice are put forward.


Zou B.,Hubei University | Li L.,Hubei University | Xu Z.,Xi'an Jiaotong University | Luo T.,Xi'an Jiaotong University | Tang Y.Y.,Macau University of Science and Technology
IEEE Transactions on Neural Networks and Learning Systems | Year: 2013

Fisher linear discriminant (FLD) is a well-known method for dimensionality reduction and classification that projects high-dimensional data onto a low-dimensional space where the data achieves maximum class separability. The previous works describing the generalization ability of FLD have usually been based on the assumption of independent and identically distributed (i.i.d.) samples. In this paper, we go far beyond this classical framework by studying the generalization ability of FLD based on Markov sampling. We first establish the bounds on the generalization performance of FLD based on uniformly ergodic Markov chain (u.e.M.c.) samples, and prove that FLD based on u.e.M.c. samples is consistent. By following the enlightening idea from Markov chain Monto Carlo methods, we also introduce a Markov sampling algorithm for FLD to generate u.e.M.c. samples from a given data of finite size. Through simulation studies and numerical studies on benchmark repository using FLD, we find that FLD based on u.e.M.c. samples generated by Markov sampling can provide smaller misclassification rates compared to i.i.d. samples. © 2012 IEEE.


Yang J.,Xiangtan University | Li W.,Xiangtan University | Li W.,Hubei University
Journal of Alloys and Compounds | Year: 2013

A low-cost and simple methodology is successfully developed for preparation of superhydrophobic surfaces on Al alloys. By the selection of an optimal concentration of the etching solution, a relatively large contact angle of 160° and a small roll angle small to 4° can be achieved. Such superhydrophobic surfaces also exhibit the remarkable anti-icing characteristics. In particular, the icing time on the surfaces can be delayed considerably. Therefore our study suggests that the present methodology and the prepared superhydrophobic surfaces could be applied in various engineering fields. © 2013 Elsevier B.V. All rights reserved.


Wu L.,Hubei University | Lu H.,Hubei University | Xiao L.,Central China Normal University | Ai X.,Hubei University | And 2 more authors.
Journal of Materials Chemistry A | Year: 2015

Pitaya-like Sb@C microspheres are prepared successfully by facile aerosol spray drying synthesis. Structural and morphological characterizations reveal that the Sb@C microspheres have a uniform pitaya-like structure, with well crystallized Sb nanoparticles embedded homogeneously in the carbon matrix. The Sb@C microsphere electrodes exhibit high Na storage capacity of 655 mA h g-1 at C/15 with excellent cyclability (93% of capacity retention over 100 cycles), as well as remarkable rate capability. Also, the morphological evolution of the Sb@C microspheres is unravelled to account for its excellent electrochemical performance, caused by maintenance of the pitaya-like configuration during cycling. This structural stability guarantees tight contact of Sb with carbon buffer, as well as uniform distribution of Sb to balance the localized mechanical stress, ensuring excellent electrochemical performance. The structural design and synthetic method reported in this work may provide an effective way to stabilize electrochemical performance of Na-storable alloy materials and therefore provide a new prospect for creation of cycle-stable alloy anodes for high capacity Na-ion batteries. © 2015 The Royal Society of Chemistry.


Wen J.,Rutgers University | Jiang J.,Hubei University | Zhang X.,Rutgers University
Organic Letters | Year: 2016

The strategy of secondary interaction enables enantioselectivity for homogeneous hydrogenation. By introducing hydrogen bonding of substrates with thiourea from the ligand, α,β-unsaturated carbonyl compounds, such as amides and esters, are hydrogenated with high enantiomeric excess. The substrate scope for this chemical transformation is broad with various substituents at the β-position. Control experiments revealed that each unit of the ligand ZhaoPhos is irreplaceable. No nonlinear effect was observed for this Rh/ZhaoPhos-catalyzed asymmetric hydrogenation. © 2016 American Chemical Society.


Wu J.,Hubei University | Wu J.,CAS Institute of Automation
Journal of Informetrics | Year: 2015

Distributing scientific funding to the suitable universities and research fields is very important to the innovation acceleration in science and technology. Using a longitudinal panel dataset of the National Natural Science Foundation of China (NSFC), the total 224,087 sponsored projects is utilized to investigate the distributions of scientific funding across universities and research disciplines. The inequality of funding distribution is studied through the investigation of Gini coefficient, and its fundamental rules are discovered through the technique of distribution fitting. It is found that the inequality of distributions of NSFC funding across 1971 universities is decreasing, and the distribution of funding and supported universities of 971 research fields follow Generalized Pareto distribution and Geometric distribution function, respectively. This study is dedicated to give an entire landscape to help make policy of distributing scientific funding. © 2015 Elsevier Ltd.


Bond D.P.G.,University of Leeds | Hilton J.,University of Birmingham | Wignall P.B.,University of Leeds | Ali J.R.,University of Hong Kong | And 3 more authors.
Earth-Science Reviews | Year: 2010

A Middle Permian mass extinction, first discovered in 1994, has become known as the "end-Guadalupian event" in the literature. However, recent studies of foraminifera- and brachiopod-range truncations in conodont-dated sections on the South China Block have shown that the losses occur below this level, in the middle of the Capitanian Stage. Extinctions were suffered by several other groups, notably the corals, whilst the mollusc record is more enigmatic. A major bivalve crisis has been reported in some studies, the giant alatoconchids being notable victims, but not others. Gastropods were unaffected by the crisis whilst a roughly contemporaneous ammonoid mass extinction may have occurred in the Early Wuchiapingian, a few million years after the main marine losses. Compilation of data from plant species in South China reveals a significant 24% loss, suggesting that the Capitanian crisis also occurred on land. An intra-Capitanian extinction of 56% of plant species in North China Block sequences may also have coincided with these losses. Correlation of these marine and terrestrial extinction events, using the palaeomagnetic record, provides two alternatives: either turnover amongst plant species is contemporaneous with the marine extinction (and the eruption of the Emeishan flood basalt province in southwest China); or plant losses post-date the marine extinction and instead coincide with the waning phase of the igneous province. Current understanding of the major dinocephalian extinction suggests this event occurred during the preceding stage (the Wordian), but future improvements in both sampling and dating this tetrapod crisis may reveal a synchronicity of plant, animal and marine invertebrate extinctions. The clear temporal link of the Capitanian marine extinction with Emeishan volcanism suggests that these flood basalt eruptions triggered the crisis. A contemporaneous, major negative C isotope excursion suggests that, like many other mass extinction events, methane release from hydrates may also be implicated. However, in the best-dated Chinese sections the main excursion is found to slightly post-date the extinction which occurs at the end of an unusual (and unexplained) interval of exceptionally heavy δ13C values. Other "usual suspects" for mass extinctions either lack geological and palaeontological evidence (e.g. marine anoxia and global cooling) or do not precisely correlate with the extinction (e.g. major, eustatic regression). © 2010 Elsevier B.V.


Wu X.,Hubei University | Zhou C.,Hong Kong Baptist University | Chen G.,City University of Hong Kong | Lu J.,Hubei University
Chaos | Year: 2011

How to recover the underlying connection topology of a complex network from observed time series of a component variable of each node subject to random perturbations is studied. A new technique termed Piecewise Granger Causality is proposed. The validity of the new approach is illustrated with two FitzHugh-Nagumo neurobiological networks by only observing the membrane potential of each neuron, where the neurons are coupled linearly and nonlinearly, respectively. Comparison with the traditional Granger causality test is performed, and it is found that the new approach outperforms the traditional one. The impact of the network coupling strength and the noise intensity, as well as the data length of each partition of the time series, is further analyzed in detail. Finally, an application to a network composed of coupled chaotic Rössler systems is provided for further validation of the new method. © 2011 American Institute of Physics.


Zeng X.,Hubei University | Carlet C.,French National Center for Scientific Research | Shan J.,Hubei University | Hu L.,University of Chinese Academy of Sciences
IEEE Transactions on Information Theory | Year: 2011

In this paper, three constructions of balanced Boolean functions with optimal algebraic immunity are proposed. It is checked that, at least for small numbers of input variables, these functions have good behavior against fast algebraic attacks as well. Other cryptographic properties such as algebraic degree and nonlinearity of the constructed functions are also analyzed. Lower bounds on the nonlinearity are proved, which are similar to the best bounds obtained for known Boolean functions resisting algebraic attacks and fast algebraic attacks. Moreover, it is checked that for the number n of variables with 5≤ n ≤ 19, the proposed n-variable Boolean functions have in fact very good nonlinearity. © 2011 IEEE.


Yan Y.E.,Hubei University | Turale S.,Ewha Womans University | Stone T.,Yamaguchi University | Petrini M.,Hubei University
International Nursing Review | Year: 2015

Background: Globally, nurses becoming more aware of getting better prepared for disaster relief, but in China, disaster nursing knowledge, courses and research are still limited. Introduction: China has long been prone to disasters, but disaster nursing education and training is in its infancy. Aim: This study explored the skills, knowledge and attitudes required by registered nurses from across China who worked in the aftermath of three large earthquakes to try to determine future disaster nursing education requirements. Method: The Questionnaire ofNurses'DisasterNursingSkills atEarthquakeSites, assessing nursing skills, knowledge and attitudes, was distributed to 139 registered nurses in 38 hospitals in 13 provinces across China who had worked in one or more earthquake disaster zones. Descriptive statistics were used for quantitative data, and content analysis for qualitative data. Results: Eighty-nine questionnaires were returned, a response rate of 68.3%. No respondent had ever received specific disaster nursing training prior to their post-earthquake nursing. Skills most often used by respondents were haemostasis bandaging, fixation, manual handling, observation and monitoring, debridement and dressing, and mass casualty transportation. Respondents identified that the most important groups of skills required were cardiopulmonary resuscitation; haemostasis, bandaging, fixation, and manual handling; and emergency management. They emphasized the need for psychological care of victims as well as that of fellow health workers. Conclusion: No respondent had ever received disaster nursing training prior to engagement at the earthquake disaster sites. All believed that there were important gaps in their knowledge and skills, and supported disaster nursing courses in the future. Implications for nursing and health policy: China urgently needs to develop disaster nursing courses, with the support of nurse leaders, educationalists and government, to implement training using an all hazards approach in accordance with international best practice and trainees' background clinical experience and knowledge. International Nursing Review © 2015 International Council of Nurses.


Du J.,Nanchang University | Yang M.-N.,University of Manchester | Yang S.-F.,Hubei University
Applied Thermal Engineering | Year: 2016

In this paper, the study is focused on a double flow plate-fin heat exchanger (PFHE) which heat transfer element is staggered offset fin, and heat transfer model and the energy equations for the structure have been established, seven geometric parameters such as the fin height, fin length and fin wrinkling angle are taken as the decision variables for optimization. A genetic algorithm (GA) combined with orthogonal design is used to search for the optimal overall structure and the correlations about the fin heat transfer factor j and the friction factor f. The maximum total heat transfer rate and the minimum total pressure drop are taken as objective functions in the GA, respectively. Performance of the optimized structure is evaluated and correspondingly the heat transfer and hydrodynamic characteristics of the full-size PFHE are calculated by using a porous media approach. Numerical results show that the total heat transfer rate of the optimized structure is improved about 6.2% comparing with the original design, the total pressure drop decreases by about 40% and the volume can reduce about 2.7%. © 2016 Elsevier Ltd


Li L.,Hubei University | Li L.,Key Laboratory of Green Preparation and Application for Materials | Liu X.L.,Hubei University | Geng H.Y.,Hubei University | And 3 more authors.
Journal of Materials Chemistry A | Year: 2013

The adsorption of methylene blue (MB) from aqueous solution on a HKUST-1/GO (MOFs:HKUST-1) composite was studied in view of the adsorption isotherm, kinetics and regeneration of the sorbent. The adsorption isotherms of methylene blue (MB) on the HKUST-1/GO composite followed both the Freundlich isotherm and the Langmuir isotherm. Adsorption kinetics and thermodynamic parameters were determined from the experimental data. The used HKUST-1/GO could be regenerated by acetone, so it can be recycled for reuse. The high adsorption capacity and excellent reusability make HKUST-1/GO attractive for the removal of MB from aqueous solution. © 2013 The Royal Society of Chemistry.


Guo Q.,Hubei University | Reardon E.J.,University of Waterloo
Applied Clay Science | Year: 2012

Fluoride removal from water by a mechanochemically synthesized anion clay (meixnerite) and its calcination product was studied at initial fluoride:meixnerite molar ratios (F I:meix) of 0.1 to 2.0 - the theoretical fluoride uptake limit for meixnerite. Fluoride removal efficiency of calcined meixnerite was higher than uncalcined meixnerite at the same F I:meix, and the difference increased as the initial fluoride concentration increased. For the sorption runs performed at F I:meix=2.0, 29% and 52% of the uptake capacity were attained for the uncalcined and calcined meixnerites, respectively. Analysis of sorption reaction rate data indicates that fluoride diffusion from solution to intraparticle active sites and its chemical sorption on active sites are important mechanisms in the uptake for both meixnerites, and the intraparticle fluoride diffusion in uncalcined meixnerite was slower than in calcined meixnerite. Moreover, XRD analyses indicate that secondary fluoride-containing phases (nordstrandite and sellaite) precipitated at high initial fluoride concentrations. When fluoride precipitates did not form at lower F I:meix (<0.6), the higher fluoride uptake by calcined meixnerite is promoted by greater availability of F - ions to the meixnerite interlayers since the interlayers were generated during reaction of the F-containing solution with the calcined material. Thus some F - did not have to diffuse into the interlayers to replace existing OH - ions as it did for the uncalcined meixnerite. At F I:meix≥0.6, precipitation of F-bearing nordstrandite also contributes to calcined meixnerite's improved ability to remove fluoride. © 2011 Elsevier B.V.


Wan N.,Texas State University | Zhan F.B.,Texas State University | Zhan F.B.,Hubei University | Lu Y.,Texas State University | Tiefenbacher J.P.,Texas State University
Health and Place | Year: 2012

This paper reports a study examining the association between colorectal cancer (CRC) survival and access to healthcare in Texas using data from the Texas cancer registry. We geo-referenced the data to the census tract level and used an enhanced 2-step floating catchment area method and factor analysis to estimate people's spatial and non-spatial access to healthcare. In addition, Cox proportional hazard regression was employed to assess the influence of different factors on CRC survival, and a spatial scan statistic was used to investigate the geographic disparity of CRC survival and the influence of access to healthcare. The analyses revealed that Hispanics, non-Hispanic blacks, and residents from several regions in Texas were more likely to die from CRC than others. Disadvantaged population groups based on factors rather than spatial access had an increased risk of CRC-specific mortality. Spatial access to oncologists has a significant association with CRC survival in non-urban areas but not in urban areas. Geographic disparities of CRC survival were largely influenced by factors rather than spatial access to healthcare. © 2011 Elsevier Ltd.


Tian N.,Texas State University | Gaines Wilson J.,University of Texas at Brownsville | Benjamin Zhan F.,Texas State University | Benjamin Zhan F.,Hubei University
Health and Place | Year: 2010

Although breast cancer is the second leading cause of cancer deaths among women in the Unites States, to date there have been no nationwide studies systematically analyzing geographic variation and clustering. An assessment of spatial-temporal clusters of cancer mortality by age and race at the county level in the lower 48 United States indicated a primary cluster in the Northeast US for both younger (RR=1.349; all RR are p≤0.001) and older (RR=1.283) women in the all-race category. Similar cluster patterns in the North were detected for younger (RR=1.390) and older (RR=1.292) white women. The cluster for both younger (RR=1.337) and older (RR=1.251) black women was found in the Midwest. The clusters for all other racial groups combined were in the West for both younger (RR=1.682) and older (RR=1.542) groups. Regression model results suggest that lower socioeconomic status (SES) was more protective than higher status at every quartile step (Medium-high SES, OR=0.374; Medium-low, OR=0.137; Low, OR=0.061). This study may provide insight to aid in identifying geographic areas and subpopulations at increased risk for breast cancer. © 2009 Elsevier Ltd. All rights reserved.


Yang X.,Hubei University | Yang X.,Georgia State University | Wang X.,Wake forest University | Liu D.,Hubei University | And 5 more authors.
Molecular Endocrinology | Year: 2014

Adipose tissue macrophages (ATMs) undergo a phenotypic switch from alternatively activated antiinflammatory M2 macrophages in lean individuals to classically activated proinflammatory M1 macrophages in obese subjects. However, the molecular mechanism underlying this process remains unclear. In this study we aim to determine whether DNA methyltransferase 3b (DNMT3b) regulates macrophage polarization and inflammation. We found that the expression of DNMT3b was significantly induced in macrophages exposed to the saturated fatty acid stearate, was higher in ATMs isolated from obese mice, but was significantly lower in alternatively activated M2 vs classically activated M1 ATMs, suggesting a role for DNMT3b in regulation of macrophage polarization and inflammation in obesity. DNMT3b knockdown promoted macrophage polarization to alternatively activated M2 phenotype and suppressed macrophage inflammation, whereas overexpressing DNMT3b did the opposite. Importantly, in a macrophage-adipocyte coculture system, we found that DNMT3b knockdown significantly improved adipocyte insulin signaling. The promoter of peroxisome proliferator activated receptor (PPAR)γ1, a key transcriptional factor that regulates macrophage polarization, is enriched with CpG sites. Chromatin immunoprecipitation assays showed that DNMT3b bound to the methylation region at PPARγ1 promoter, which was further enhanced by stearate. Moreover, pyrosequencing analysis revealed that stearate increased DNA methylation at PPARγ1, which was prevented by DNMT3b deficiency. Therefore, our data demonstrate that DNMT3b plays an important role in regulating macrophage polarization through epigenetic mechanisms. In obesity, elevated saturated fatty acids enhance DNMT3b expression, leading to DNA methylation at the PPARγ1 promoter, which may contribute to deregulated adipose tissue macrophage polarization, inflammation, and insulin resistance. © 2014 by the Endocrine Society.


Xiong Y.-H.,Hubei University | Xiong Y.-H.,Peoples Hospital of Gansu Province | He L.,Hubei University | Fei J.,Nanchang University
International Immunopharmacology | Year: 2014

Cytotoxic T-lymphocyte antigen-4 (CTLA-4), a molecule expressed predominantly on activated T cells, plays an important role in the down-regulation of T-cell activation. To evaluate the potential effects of CTLA-4 gene polymorphisms on susceptibility to cervical cancer, we genotyped polymorphisms in CTLA-4 (- 318 T/C, CT60 G/A, + 49 G/A, - 658 T/C, and - 1661 G/A) and calculated odds ratios for the genotype and allele distributions between patients and controls. We then examined the functional relevance of the polymorphisms using enzyme-linked immunosorbent assays (ELISAs), in vitro lymphocyte proliferation assay, and cytotoxic assay. The CTLA-4 - 318 CC, CT60 AA, and + 49 GG genotype frequencies were lower in patients than in controls (p < 0.05). The frequencies of CTLA-4 - 318 T allele and CT60G allele carriers were significantly higher in patients than in controls (p < 0.05). Upon stimulation, peripheral blood mononuclear cells (PBMCs) carrying the - 318TT and CT60GG genotypes exhibited significantly lower proliferation, IL-2, and IL-4 levels; fewer cytolytic activities; and higher TGF-β levels compared with PBMCs carrying the - 318 CC/CT or CT60 AA/AG genotypes. We also found that CTLA-4 - 318 T/C and CT60 G/A single nucleotide polymorphisms were associated with the severity of cervical cancer. These results indicate that CTLA-4 - 318 T/C and CT60 G/A can affect cervical cancer susceptibility by altering the immune status of an individual. © 2013 Elsevier B.V. All rights reserved.


Chen H.,Nanchang University | Hu P.,Hubei University
IET Control Theory and Applications | Year: 2013

This article mainly studies the problem of the exponential stability for singular systems with two interval timevarying delays. By constructing a modified Lyapunov-Krasovskii functional (LKF) and utilising a convex polyhedron method to estimate the derivative of LKF, some new delay-dependent criteria can be established in terms of linear matrix inequalities. Compared with some existing literatures, the novelties in this study are that the needed decisive variables are fewer and the obtained delay-dependent stability criteria are less conservative. Finally, two illustrative numerical examples are given to show the effectiveness of the derived results. © The Institution of Engineering and Technology 2013.


Shen J.-J.,PLA Academy of National Defense Information | Yang C.-L.,Hubei University | Xu Y.-Q.,PLA Academy of National Defense Information
Advanced Materials Research | Year: 2014

The traditional Tactical Internet (TI) simulative training didn't consider the terrain environment and maneuver simulation, so its fidelity was low. The paper aimed to resolve it. Firstly, the paper gave the modeling process of TI terrain environment, and put forward the corresponding ways to some parts of the modeling process. Secondly, the paper gave the optimization steps of TI terrain model, it improved the simulation running efficiency; and then the paper utilized the large area database management technique to solve dynamic loading and rendering problem of large terrain model. Lastly, the paper gave the maneuver simulation way to the communication vehicles of TI, it solved the problems of maneuver collision and precise maneuvering along the road. The paper presented the realization results in each part, and it proved the effectiveness of the given ways. © (2014) Trans Tech Publications, Switzerland.


Tian J.,Texas State University | Zhao N.,Mayan Esteem Project | Samson E.L.,Beijing Institute of Technology | Wang S.,Hubei University
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing | Year: 2014

Since economic reforms in 1978, China's huge growth has led to a rapid increase in demand for freight traffic. Timely assessments of past and current amounts of freight traffic are basis for predicting future demands of freight traffic and appropriately allocating transportation resources. Sum lights (summed digital number (DN) value of pixels of nighttime light imagery) for years 2000, 2004, and 2008 respectively are extracted from corresponding Defense Meteorological Satellite Program's Operational Linescan System (DMSP-OLS) stable lights annual image composites. The sum lights are then regressed on total freight traffic (TFT), railway freight traffic (RFT), and highway freight traffic (HFT), respectively, at the province level. Results show that sum light strongly correlates to TFT and HFT, so sum light can be used as a proxy for TFT and HFT at the province level. However, due to lack of strong correlations between RFT and GDP, sum light is not appropriate to be as a proxy of RFT. Finally we disaggregate each province/municipality's HFT to each pixel in proportion to the DN value of the pixel of the nighttime light image to produce a Chinese HFT map of 2008 with 1 km x 1 km resolution. Compared to traditional census-based freight traffic data, the freight traffic data derived from the nighttime light imagery contain more spatial information. © 2013 IEEE.


Wang M.,Hubei University | Hu F.,Satellite Surveying and Mapping Application Center | Li J.,University of Waterloo
ISPRS Journal of Photogrammetry and Remote Sensing | Year: 2011

This paper presents a practical epipolarity model for high-resolution linear pushbroom satellite images acquired in either along-track or cross-track mode, based on the projection reference plane in object space. A new method for epipolar resampling of satellite stereo imagery based on this model is then developed. In this method, the pixel-to-pixel relationship between the original image and the generated epipolar image is established directly by the geometric sensor model. The approximate epipolar images are generated in a manner similar to digital image rectification. In addition, by arranging the approximate epipolar lines on the defined projection reference plane, a stereoscopic model with consistent ground sampling distance and parallel to the object space is thus available, which is more convenient for three-dimensional measurement and interpretation. The results obtained from SPOT5, IKONOS, IRS-P5, and QuickBird stereo images indicate that the generated epipolar images all achieve high accuracy. Moreover, the vertical parallaxes at check points are at sub-pixel level, thus proving the feasibility, correctness, and applicability of the method. © 2011 International Society for Photogrammetry and Remote Sensing, Inc. (ISPRS).


Jingyan S.,Wuhan Bioengineering Institute | Yuwen L.,Hubei University | Zhiyong W.,Hubei University | Cunxin W.,Hubei University
Journal of Pharmaceutical and Biomedical Analysis | Year: 2013

The thermal behavior of dry solid ascorbic acid in nitrogen atmosphere in the temperature range of 25-800°C was investigated by TG-FTIR. During the thermal decomposition process, five evolved gaseous species, including H2O, CO2, CO, CH4 and HCOOH, were identified and monitored, in which HCOOH was detected for the first time. The results indicated that ascorbic acid began to decompose at 191°C. Its decomposition process consisted of three stages, and dehydration and decarboxylation to form furfural were the possible principal mechanism. The kinetic analysis for the first decomposition stage was also carried out by the isoconversional method and the master plots method. The results indicated that this process can be described by the model of 1st order reaction. © 2013 Elsevier B.V.


Magney T.S.,University of Idaho | Eusden S.A.,Bowdoin College | Eitel J.U.H.,University of Idaho | Logan B.A.,Bowdoin College | And 3 more authors.
New Phytologist | Year: 2014

Summary: Terrestrial laser scanning (TLS) data allow spatially explicit (x, y, z) laser return intensities to be recorded throughout a plant canopy, which could considerably improve our understanding of how physiological processes vary in three-dimensional space. However, the utility of TLS data for the quantification of plant physiological properties remains largely unexplored. Here, we test whether the laser return intensity of green (532-nm) TLS correlates with changes in the de-epoxidation state of the xanthophyll cycle and photoprotective non-photochemical quenching (NPQ), and compare the ability of TLS to quantify these parameters with the passively measured photochemical reflectance index (PRI). We exposed leaves from five plant species to increasing light intensities to induce NPQ and de-epoxidation of violaxanthin (V) to antheraxanthin (A) and zeaxanthin (Z). At each light intensity, the green laser return intensity (GLRI), narrowband spectral reflectance, chlorophyll fluorescence emission and xanthophyll cycle pigment composition were recorded. Strong relationships between both predictor variables (GLRI, PRI) and both explanatory variables (NPQ, xanthophyll cycle de-epoxidation) were observed. GLRI holds promise to provide detailed (mm) information about plant physiological status to improve our understanding of the patterns and mechanisms driving foliar photoprotection. We discuss the potential for scaling these laboratory data to three-dimensional canopy space. © 2013 New Phytologist Trust.


Li L.,Hubei University | Davis A.P.,University of Maryland University College
Environmental Science and Technology | Year: 2014

Multiple chemical forms of nitrogen in urban stormwater make its management challenging. Sixteen storm events were monitored and analyzed for total nitrogen (TN), particulate organic nitrogen (PON), nitrate (NO3-N), nitrite (NO2-N), ammonium (NH3-N), and dissolved organic nitrogen (DON) in stormwater runoff and in treated discharge through a conventional bioretention cell. Influent PON can be effectively removed via bioretention sedimentation/filtration, NH3-N by ion exchange/sorption, and NO2-N by oxidation. However, significant DON and NO3-N leached from the bioretention cell, resulting in only 9% net overall TN concentration reduction. Captured PON and vegetation detritus in the bioretention cell can be leached as DON or mineralized into NO 3-N. The effluent N is dominated by NO3-N (46%) and DON (42%). Therefore, in addition to creating denitrification conditions for NO 3-N, preventing DON leaching is also critical for effective nitrogen removal though bioretention systems. The bioretention cell exhibited a moderate mass load reduction for TN (41%), which mainly results from runoff volume reduction. © 2014 American Chemical Society.


Tan X.,Hubei University
Energy Education Science and Technology Part A: Energy Science and Research | Year: 2014

With the wide application of web big data, in response to the Internet users are about the same theme of mass information effectively filter and extraction, this paper focus on this news mining and fusion of large scale usage data in web big data and proposes a document based on particle size of the news MGNF fusion algorithm, particle size document means that face now the newest microblog and short documents and traditional news dissemination documents, both document length although different, but as based on the calculation of grassroots journalism and communication mode. Through mining the different particle size of the document different views, we can find out the potential to be found for the information. The experimental results verify the effectiveness and energy cost efficiently of the proposed algorithm. © Sila Science. All Rights Reserved.


Wang X.,Hubei University | Liu T.,Hubei University | He Q.,Hubei University | Wang Y.,Hubei University | Zhang X.,Hubei University
PLoS ONE | Year: 2014

Prostate cancer is relatively common cancer occurring in males. Radical prostatectomy (RP) is the most effective treatment for a localized tumor but erectile dysfunction (ED) is common complication, even when bilateral nerve-sparing RP (BNSRP) is performed. Clinical trials have shown varied effectiveness of phosphodiesterase type-5 inhibitors (PDE5-Is) for treatment of post-BNSRP ED, but there remains controversy over the application of this treatment and no formal systematic review and meta-analysis for the use of PDE5-Is for this condition has been conducted. This review was to systematically assess the efficacy and safety of oral PDE5-Is for post-BNSRP ED. A database search was conducted to identify randomized controlled trials (RCTs). The comparative efficacy of treatments was analyzed by fixed or random effect modeling. Erectile function was measured using the International Index of Erectile Function (IIEF), Sexual Encounter Profile (SEP) question-2, 3 and the Global Assessment Question (GAQ). The rate and incidence of adverse events (AEs) were determined. The quality of included studies was appraised using the Cochrane Collaboration bias appraisal tool. Eight RCTs were included in the analyses. PDE5-Is were effective for treating post-BNSRP ED compared to placebo when erectile function was determined using the IIEF score [mean difference (MD) 5.63, 95% confidence interval (CI) (4.26-6.99)], SEP-2 [relative risk (RR) 1.63, 95% CI (1.18-2.25) ], SEP-3 [RR 2.00, 95% CI (1.27-3.15) ] and GAQ [RR 3.35, 95% CI (2.68-4.67) ]. The subgroup analysis could find a trend that longer treatment duration, higher dosage, on-demand dosing, sildenafil and mild ED are associated with more responsiveness to PDE5-Is. PDE5-Is were overall well tolerated with headache being the most commonly reported AE. Our data provides compelling evidence for the use of PDE5-Is as a primary treatment for post-BNSRP ED. However, further studies are required to optomize usage parameters (such as dosage and duration of treatment). © 2014 Wang et al.


Wang Z.,University of British Columbia | Wang Z.,Hubei University | Shen Y.,University of British Columbia | Haapasalo M.,University of British Columbia
Dental Materials | Year: 2014

Objectives Oral bacteria have evolved to form biofilms on hard tooth surfaces and dental materials. The antibiofilm effect of materials used for the restoration of oral function affects oral health. In this review we describe the features involved in the formation of oral biofilms on different surfaces in the oral cavity and the antibiofilm properties of dental materials. Methods An electronic search of scientific papers from 1987 to 2013 was performed with PubMed, ScienceDirect and Google search engines using the following search terms: antibiofilm, dental material, dental hard tissue, endodontic material, implant material, oral biofilm, and restorative material. Results Selected inclusion criteria resulted in 179 citations from the scientific, peer-reviewed literature. Oral biofilms form not only on dental hard tissue, but also on a wide range of dental materials used in cariology, endodontics, restorative dentistry and periodontology, resulting in destruction of dental hard tissue and even infection. Therefore, there has been a continuous effort to develop the antibiofilm properties of dental materials used for different purposes. Specific antimicrobial design in the composition and application of new materials (e.g. bioceramic sealer, resin composite, implant coating) demonstrates an improvement of the antibiofilm properties of these materials compared to earlier generations. Significance A significant number of dental materials have been shown to affect biofilm growth by inhibiting the adhesion of bacteria, limiting their growth or killing microbes in the biofilms formed in vitro. Incorporation of an appropriate amount of antibacterial agent could provide dental materials with antibiofilm activity without significantly influencing their mechanical properties. However, more randomized and double-blind clinical studies of sufficient length with these materials are needed to confirm long term success following their use in the dental clinic. © 2013 Academy of Dental Materials.


Zhang X.,Hubei University | Zuo X.,Hubei University | Yang B.,Hubei University | Li Z.,Hubei University | And 14 more authors.
Cell | Year: 2014

MicroRNAs are well known to mediate translational repression and mRNA degradation in the cytoplasm. Various microRNAs have also been detected in membrane-compartmentalized organelles, but the functional significance has remained elusive. Here, we report that miR-1, a microRNA specifically induced during myogenesis, efficiently enters the mitochondria where it unexpectedly stimulates, rather than represses, the translation of specific mitochondrial genome-encoded transcripts. We show that this positive effect requires specific miR:mRNA base-pairing and Ago2, but not its functional partner GW182, which is excluded from the mitochondria. We provide evidence for the direct action of Ago2 in mitochondrial translation by crosslinking immunoprecipitation coupled with deep sequencing (CLIP-seq), functional rescue with mitochondria-targeted Ago2, and selective inhibition of the microRNA machinery in the cytoplasm. These findings unveil a positive function of microRNA in mitochondrial translation and suggest a highly coordinated myogenic program via miR-1-mediated translational stimulation in the mitochondria and repression in the cytoplasm. © 2014 Elsevier Inc.


Wan X.,Hubei University
IET Conference Publications | Year: 2013

VHF radar shows great promise in detecting stealth targets, since it works in resonance regions. Wideband VHF radar, as a new radar system, has an enormous potential. In this paper, target detection with wideband VHF radar that compensates for the fluctuation of targets' RCS between different frequencies in the resonance region is introduced. The Boeing 747-200 model and the Predator model were designed for the study, and the aircrafts were studied in the 40∼80MHz frequency band. Results show that: (1) the wideband detection is better than the narrowband single frequency detection; and (2) for greatly fluctuating targets, the wideband detection is better than the multi-frequency detection.


Cao N.,Hubei University | Hu K.,Hubei University | Luo W.,Hubei University | Luo W.,Suzhou University | Cheng G.,Hubei University
Journal of Alloys and Compounds | Year: 2014

Well dispersed RuCu nanoparticles (NPs) supported on graphene were in situ synthesized by a one-step co-reduction of aqueous solution of ruthenium (III) chloride, cupric (II) chloride, and graphite oxide (GO) with ammonia borane (AB) under ambient condition. The nature of the NPs was fully characterized by TEM, HRTEM, XRD, energy dispersive spectroscopy (EDX), and X-ray photoelectron spectroscopy (XPS). The as-synthesized NPs exhibit much higher catalytic activity for hydrolytic dehydrogenation of AB than the monometallic Ru and Cu, bimetallic RuCu/graphene reduced by NaBH4, and graphene free RuCu counterparts. Additionally, the as-synthesized NPs supported on graphene exhibit higher catalytic activity than the catalysts with other conventional supports, such as SiO2, γ-Al2O3, and carbon black. The activity of Ru1Cu7.5/graphene NPs in terms of turnover frequency (TOF) is 135 mol H2 min-1 (mol Ru) -1, which is higher than Ru/graphene, and most reported Ru-based or other noble metal-based NPs for the catalytic hydrolysis of AB. The activation energy for hydrolysis of AB in the presence of Ru1Cu 7.5/graphene NPs was determined as 30.59 kJ mol-1, which is lower than most of the reported catalysts. Furthermore, the as-prepared NPs exert satisfied durable stability for the hydrolytic dehydrogenation of AB.


Zhu T.,Hubei University | Qin J.,Hubei University | Halasyamani P.S.,University of Houston
Dalton Transactions | Year: 2011

Two new mixed-valent tellurium oxides with vanadium(v), A4V 6[Te2 4+Te6+]O24 (A = K and Rb), have been synthesized by hydrothermal and conventional solid state techniques. Their structures were determined by single-crystal X-ray diffraction analysis. These two iso-structural compounds exhibit layered structural topologies consisting of [V6Te3O24] 4- anionic units. In these anionic structural units, a Te 6+O6 octahedron is connected to six VO4 tetrahedra by corner-sharing to generate a [V6TeO24] unit, and each of these [V6TeO24] units are interconnected by sharing two Te4+O3 polyhedra to complete the infinite [V6Te3O24]4- sheets. Infrared spectroscopy, UV-Visible diffuse reflectance spectroscopy, and thermogravimetric analysis were also performed on these two compounds. Crystal data: K 4V6Te3O24, trigonal, space group R3c (No. 167) with a = b = 9.7075(6) Å, c = 42.701(3) Å, V = 3484.9(4) Å3, and Z = 6; Rb4V6Te3O 24, trigonal, space group R3c (No. 167) with a = b = 9.8399(9) Å, c = 43.012(4) Å, V = 3606.6(6) Å3, and Z = 6. © The Royal Society of Chemistry 2011.


Wang G.,Hubei University | Wang G.,CAS Lanzhou Institute of Chemical Physics | Wang H.,CAS Lanzhou Institute of Chemical Physics | Guo Z.,Hubei University | Guo Z.,CAS Lanzhou Institute of Chemical Physics
Chemical Communications | Year: 2013

A thin film of polyaniline (PANI) nanofibers on the stainless steels with fluoro-thiol modification was prepared through an optimal polymerization time of aniline using HClO4 as a dopant, showing robust superhydrophobic, transparent and anti-fingerprint properties. © 2013 The Royal Society of Chemistry.


Ke J.,Hubei University | He C.,Hubei University | Liu H.,Hubei University | Li M.,Hubei University | And 2 more authors.
Chemical Communications | Year: 2013

A novel silver-mediated highly selective synthesis of polysubstituted pyrroles by the C-H/C-H oxidative cross-coupling/cyclization of terminal alkynes with β-enamino esters has been developed. This protocol represents a simple, efficient and selective way to construct polysubstituted pyrroles in good yields from basic chemical materials. © 2013 The Royal Society of Chemistry.


Lu Y.,Hubei University | Li T.,Renmin University of China | Zhao X.,Renmin University of China | Li M.,Renmin University of China | And 3 more authors.
Biomaterials | Year: 2010

The search for new electrode materials including new electrode modification methods is crucial for improving long-term performance of neuroprosthetic devices. In this study, an investigation of electrochemically co-deposited polypyrrole/single-walled carbon nanotube (PPy/SWCNT) films for improving the electrode-neural interface was reported. The PPy/SWCNT microelectrodes exhibited a particularly high safe charge injection (Qinj) limit of ∼7.5mC/cm2 and low electrode impedance at 1kHz, as well as good stability. Cell attachment and neurite outgrowth of rat pheochromocytoma (PC12) cells on the PPy/SWCNT deposited substrates were clearly observed by Calcein-AM staining and scanning electron microscope (SEM) analysis. Furthermore, tissue response was studied by a 6-week implantation in the cortex of rats. A significantly lower (p<0.05) glial fibrillary acidic protein (GFAP) and higher (p<0.05) neuronal nuclei (NeuN) immunostaining were found on comparison of the test group (n=11) with the control group (n=8), in the zone within the distance of 100μm to the implant interface. All of these characteristics are desirable for chronically implantable neural probes with high density microelectrodes. Importantly, this technique can easily incorporate other modification methods to build a more advanced electrode-neural interface. © 2010 Elsevier Ltd.


Huang S.,Hubei University | Li X.,Chengdu University of Technology | Wang Y.,Hubei University
Environmental Earth Sciences | Year: 2012

A new evaluation model for geo-environmental impact assessment of mining (GEIAM) is proposed. The evaluation framework in this model considers three groups of criteria, namely, geo-hazards risks, environmental risks, and resource damages. Fuzzy-analytic hierarchy process (AHP) was used to establish a multiple-criteria evaluation system and simultaneously command weighting to avoid vagueness and ambiguity in expert judgment. Membership function was employed to deal with the vagueness boundary problem of indices scoring and to help complete the ultimate fuzzy synthetic ranking. The model expresses the evaluation results with an integrated objective ranking and three criteria ranking. It was tentatively applied to assess an opencast limestone mine. The results indicated that the indices sequences were consistent with the mine background and the expert professional experience and better revealed the impact of geo-hazards risks. Specific assessment factors such as geo-hazards potential, engineering geological condition, and hydrogeological condition were prioritized for further improvement. Compared with existing GEIAM evaluation methods, the proposed assessment model focuses more on expert experience and judgment, breaks through the limitation of local estimation to variable attributes and, most importantly, satisfies the multi-purpose requirements to incorporate real considerations together for mining safety, geo-environmental protection, and natural resource conservation. © 2011 Springer-Verlag.


Branched-chain amino acid aminotransferase (BCAT) plays a key role in the biosynthesis of hydrophobic amino acids (such as leucine, isoleucine and valine), and its substrate spectrum has not been fully explored or exploited owing to the inescapable restrictions of previous assays, which were mainly based on following the formation/consumption of the specific branched-chain substrates rather than the common amino group donor/acceptor. In our study, detailed measurements were made using a novel coupled assay, employing (R)-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans as an auxiliary enzyme, to provide accurate and reliable kinetic constants. We show that Escherichia coli BCAT can be used for asymmetric synthesis of a range of non-natural amino acids such as l-norleucine, l-norvaline and l-neopentylglycine and compare the kinetic results with the results of molecular modelling. A full two-substrate steady-state kinetic study for several substrates yields results consistent with a bi-bi ping-pong mechanism, and detailed analysis of the kinetic constants indicates that, for good 2-oxoacid substrates, release of 2-oxoglutarate is much slower than release of the product amino acid during the transamination reaction. The latter is in fact rate-limiting under conditions of substrate saturation. © 2013 FEBS.


Based on ZhangShi YiTong written by ZHANG Lu of Qing dynasty, and the record that external application of Baijiezi (seeds of Brassica Alba) for treating asthma of cold syndrome, retrospective study is conducted to modern literature of treating winter diseases in summer with acupoint sticking therapy for preventing and treating chronic cough and asthma. Learning from thoughts and methods of evidence-based medicine, and according to subject characteristics of TCM and acupuncture, acupoints and point-selecting discipline of prescription for preventing and treating chronic cough and asthma in summer with acupoint sticking are analyzed. The results show that the top ten common acupoints used for acupoint sticking therapy of treating winter diseases in summer are Feishu (BL 13), Dingchuan (EX-B 1), Xinshu (BL 15), Geshu (BL 17), Danzhong (CV 17), Shenshu (BL 23), Gaohuang (BL 43), Dazhui (GV 14), Pishu (BL 20), Tiantu (CV 22), most of which belong to the Bladder Meridian of Foot-Taiyang, Conception Vessel and Governor Vessel or extra-meridian points. It refers that the core acupoints of acupoint sticking therapy are Feishu (BL 13), Dingchuan (EX-B 1), Xinshu (BL 15), Geshu (BL 17), Danzhong (CV 17), and adjunct points can be selected by syndrome, disease different stage, disease or symptoms.


Pan J.,Hubei University | Li Y.,Hubei University | Han J.,Hubei University | Li G.,Hubei University | And 4 more authors.
Energy and Environmental Science | Year: 2013

Alkaline polymer electrolytes (APEs) are a new class of polyelectrolytes enabling the use of nonprecious metal catalysts in electrochemical devices, such as fuel cells and water electrolyzers. However, the current development of APEs is facing a severe difficulty, the conductivity-stability dilemma. Specifically, to acquire high ionic conductivity, the polymer backbone has to be grafted with enough cationic functional groups, typically quaternary ammonium (-NR3 +), but such a modification in structure has damaged the chemical inertness of the polymer backbone and induced degradation in an alkaline environment. Here we demonstrate a strategy for disentangling such a dilemma. To alleviate the damage to the polymer backbone, we reduce the grafting degree (GD) of functional groups, but design two cations on each grafted functional group so as to retain sufficient ion concentration. Such a seemingly simple change in structure has brought a notable effect in performance: not only can both high ionic conductivity and much improved chemical stability be achieved, but also the intermolecular interaction between polymer chains has thus been enhanced, rendering the resulting APE membrane much stronger in mechanical strength and highly anti-swelling in water even at 80 °C. © The Royal Society of Chemistry 2013.


Wang Z.,University of British Columbia | Wang Z.,Hubei University | Shen Y.,University of British Columbia | Haapasalo M.,University of British Columbia
Journal of Endodontics | Year: 2013

Introduction: This study examined the effect of the smear layer on the antibacterial effect of different disinfecting solutions in infected dentinal tubules. Methods: Cells of Enterococcus faecalis were forced into dentinal tubules according to a previously established protocol. After a 3-week incubation period of infected dentin blocks, a uniform smear layer was produced. Forty infected dentin specimens were prepared and subjected to 3 and 10 minutes of exposure to disinfecting solutions including sterile water, 2% and 6% sodium hypochlorite (NaOCl), 2% chlorhexidine (CHX), 17% EDTA, and QMiX (Dentsply Tulsa Dental, Tulsa, OK). The following combinations were also included: 2% NaOCl + 2% CHX, 2% NaOCl + QMiX, 6% NaOCl + QMiX, and 6% NaOCl + 17% EDTA + 2% CHX. Four other dentin specimens similarly infected but with no smear layer were subjected to 3 minutes of exposure to 2% CHX and 6% NaOCl for comparison. Confocal laser scanning microscopy and viability staining were used to analyze the proportions of dead and live bacteria inside the dentin. Results: In the presence of a smear layer, 10 minutes of exposure to QMiX, 2% NaOCl + QMiX, 6% NaOCl + QMiX, and 6% NaOCl + 17% EDTA + 2% CHX resulted in significantly more dead bacteria than 3 minutes of exposure to these same disinfecting solutions (P <.05). No statistically significant difference between 3 and 10 minutes was found in other groups (P >.05); 6% NaOCl + QMiX and 6% NaOCl + 17% EDTA + 2% CHX showed the strongest antibacterial effect. In the absence of a smear layer, 2% CHX and 6% NaOCl killed significantly more bacteria than they did in the presence of a smear layer (P <.05). Conclusions: The smear layer reduces the effectiveness of disinfecting agents against E. faecalis in infected dentin. Solutions containing 6% NaOCl and/or QMiX showed the highest antibacterial activity. © 2013 American Association of Endodontists.


Wang Y.C.,Hubei University
Zhongguo zhen jiu = Chinese acupuncture & moxibustion | Year: 2010

OBJECTIVE: To explore the mechanism of electroacupuncture therapy on Parkinson's disease (PD). METHODS: Fifty Wistar rats were randomly divided into a normal group, a sham-operation group, a model group, a Fengfu-Taichong group and a Shuanggu Yitong group. PD model was duplicated by microinjection of 6-Hydroxyl-Dopamine into right corpora striata, and by microinjection of normal saline in sham-operation group. Rats in normal group, sham-operation group and model group were not treated. In Fengfu-Taichong group, the rats were treated by electroacupuncture at "Fengfu" (GV 16) and "Taichong" (LR 3) on the basis of the PD model, and by electroacupuncture at "Fengfu" (GV 16), "Taichong" (LR 3), "Guanyuan" (CV 4) and "Zusanli" (ST 36) in Shuanggu Yitong group, once daily for 2 weeks. GDNF and Ret expression were detected by immunohistochemistry and western blotting, respectively. RESULTS: The number of GDNF positive cells and the content of Ret receptor increased significantly in the two electroacupuncture groups compared with those in the other groups (all P < 0.01), and the expression of GDNF increased significantly in Shuanggu Yitong group compared with that in Fengfu-Taichong group (P < 0.01). CONCLUSION: Electroacupuncture can not only increase the expression of GDNF, but also enhance its effect. "Shuanggu Yitong" method is better than simple acupuncture at "Fengfu" (GV 16) and "Taichong" (LR 3) in increasing expression of GDNF.


Du Y.,Hubei University | Cao N.,Hubei University | Yang L.,Hubei University | Luo W.,Hubei University | Cheng G.,Hubei University
New Journal of Chemistry | Year: 2013

In this study, well dispersed Cu@Co core-shell nanoparticles (NPs) on rGO surfaces were successfully synthesized via a one-step in situ procedure using methylamine borane (MeAB) as reductant under ambient conditions. The Cu@Co/rGO NPs exhibit superior catalytic activity than their alloy (CuCo/rGO) and graphene-free (Cu@Co) counterparts toward the hydrolytic dehydrogenation of ammonia borane (AB). Additionally, compared with the NPs reduced by AB, the as-synthesized Cu@Co/rGO NPs generated by the weaker reducing agent MeAB exhibit higher catalytic activities. Furthermore, the as-synthesized NPs exerted satisfactory catalytic activities and recycle stabilities for the hydrolysis of MeAB. Moreover, this general method indicates that MeAB can be used as both a potential hydrogen storage material and an efficient reductant which can be easily extended to the facile preparation of other rGO-supported metal NPs. © 2013 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.


Gao J.,Hubei University | Yu X.,Hubei University | Xie Z.,Hubei University
Journal of Bacteriology | Year: 2012

We sequenced the genome of the high-siderophore-yielding strain Pseudomonas sp. HYS and then analyzed its iron acquisition systems. The 5.6-Mb draft genome sequence has a special pattern of pyoverdine synthesis clusters and contains an hmuRSTUV heme uptake cluster, which has a homolog only in some strains of the order Enterobacteriales. © 2012, American Society for Microbiology.


Zhu R.,Hubei University | Nie Z.,Hubei University
Pediatrics and Neonatology | Year: 2016

Background We aimed to study the changes of serum N-terminal pro-brain natriuretic to peptide (NT-proBNP) levels after asphyxia-induced myocardial injury in children and explore the relationship between serum NT-proBNP levels and neonatal asphyxia. Methods One hundred and six cases of neonatal asphyxia were randomly selected for the study, including 46 severe cases with myocardial injury and 60 mild cases with no cardiac injury. Sixty-three healthy newborns were selected as the control group. The serum NT-proBNP level was detected using electrochemiluminescence. Creatine kinase MB (CK-MB) and serum sodium and calcium were measured simultaneously. Results The serum NT-proBNP level in the myocardial injury group was significantly higher than that of the noncardiac injury and control groups (p < 0.01). Asphyxia serum NT-proBNP and cardiac enzymes were significantly correlated. The median value of neonatal NT-proBNP was 1491 pg/mL at postnatal Day 3 (P3) and 1077 pg/mL at postnatal Day 14 (P14). The cutoff value for children with myocardial injury was 3612.5 pg/mL; the area under the receiver operating characteristic curve was 0.80 (p < 0.001), with a sensitivity of 83.3%, a specificity of 80.5%, a positive predictive value of 82.8%, and a negative predictive value of 79.4%. After treatment, the serum NT-proBNP level in children with myocardial damage showed a significant decrease. Conclusion The serum NT-proBNP level can reflect myocardial injury in neonates with asphyxia and can guide its diagnosis. Copyright © 2016, Taiwan Pediatric Association.


Zhang L.,Hubei University | Lou X.,Hubei University | Yu Y.,Hubei University | Qin J.,Hubei University | Li Z.,Hubei University
Macromolecules | Year: 2011

To develop sensitive and selective S2- chemosensors, a new disubstituted polyacetylene (P2) bearing pyridine moieties in the side chains was prepared conveniently through a postfunctional method, the strong green fluorescence of which could be completely quenched by Cu2+ ions at the concentration as low as 2.0 × 10-6 mol/L in diluted solutions. Based on the displacement strategy, by utilizing the much higher stability constant of the complex of S2- and Cu2+, the quenched fluorescence of the solution of P2 by Cu2+ ions could recover upon the addition of trace S2- anions, with the detection limit down to 5.0 × 10-7 mol/L. Moreover, no interference were observed from other anions, including SO3 2-, HSO 3 -, SO4 2-, ClO4 -, I-, Br-, Cl-, F-, IO3 -, HPO4 2-, PO4 3-, C2O4 2-, S2O 3 2-, CO3 2-, AcO-, CN -, and P2O7 4-, making P2 a novel, sensitive, and selective sulfide probe. © 2011 American Chemical Society.


Zhuang L.,Fudan University | Zeng X.,Hubei University | Yang Z.,Fudan University | Meng Z.,Fudan University
PLoS ONE | Year: 2013

Background: The effect of interferon(IFN) in the management of hepatocellular carcinoma (HCC) remains controversial, and no clear recommendations have been proposed. Objectives: To evaluate the effect and safety of IFN for HCC. Methods: PubMed, OvidSP, and Cochrane Library were searched from their establishment date until August 30, 2012. Studies that met the inclusion criteria were systematically evaluated and then subjected to meta-analysis. Results: Thirteen randomized control trials (RCTs) involving 1344 patients were eligible for this study. When IFN was used as an adjuvant therapy for HCC patients after curative therapy, the meta-analysis showed that IFN reduced the 1-, 2-, 3-, 4-, and 5-year recurrence rates. Subgroup analysis showed that IFN reduced the 2-, 3-, 4-, and 5-year recurrence rates of hepatitis C viral (HCV)-related HCC. The effect of IFN for on hepatitis B virus(HBV)-related HCC patients could not be determined because of isufficient data. After surgical resection, adjuvant IFN therapy reduced the 4- and 5- recurrence rates. All studies reported that IFN could not improve the overall survival of HCV-realated HCC patients after curative therapies. Only one study showed that IFN was associated with better overall survival in HCC patients after curative therapy and subgroup of HCC patients after surgical resection. Thus, meta-analysis was not performed. Different treatment options were used as control to study the effect of IFN for intermediate and advanced HCC patients, thus meta-analysis was not appropriate. All included studies, except for one, reported that IFN treatment was well tolerated. Conclusions: After curative therapies, adjuvant IFN reduced the recurrence of HCC. IFN did not improve the survival of HCV-related HCC patients after curative therapy. Whether IFN is effective for intermediate and advanced HCC patients could not be determined because of insufficient data. The toxicity of IFN was acceptable. © 2013 Zhuang et al.


Liu Q.,Hubei University | Wang X.,Hubei University
Experimental and Therapeutic Medicine | Year: 2013

Transient receptor potential vanilloid 2 (TRPV2), a nonselective cation channel, has become an attractive target gene for tumor studies due to its wide range of physiological and pathological functions. However, its specific role in bladder cancer development and progression remains unclear. The aim of the present study was to investigate the effects of TRPV2 on the proliferation, migration and invasion of 5637 bladder cancer cells in vitro. Rat TRPV2 cDNA was transfected into 5637 bladder cancer cells and changes in the behavior of the cells were detected. It was observed that TRPV2 enhanced bladder cancer cell migration and invasion; however, it did not affect cell proliferation in vitro. TRPV2 activity, which may be mediated by direct matrix metalloproteinase 2 (MMP2) regulation, is important in bladder tumor development and progression. The results of this study suggest that TRPV2 channels are a potential therapeutic target for bladder carcinoma.


Li H.,Huazhong University of Science and Technology | Wei Y.,Huazhong University of Science and Technology | Li L.,Hubei University | Yuan Y.,CAS Xi'an Institute of Optics and Precision Mechanic
Neurocomputing | Year: 2012

Recently, derived kernel method which is a hierarchical learning method and leads to an effective similarity measure has been proposed by Smale. It can be used in a variety of application domains such as object recognition, text categorization and classification of genomic data. The templates involved in the construction of the derived kernel play an important role. To learn more effective similarity measure, a new template selection method is proposed in this paper. In this method, the redundancy is reduced and the label information of the training images is used. In this way, the proposed method can obtain compact template sets with better discrimination ability. Experiments on four standard databases show that the derived kernel based on the proposed method achieves high accuracy with low computational complexity. © 2012 Elsevier B.V.


Huang Y.M.,Changzhou University | Ma Q.-L.,Hubei University | Zhai B.-G.,Changzhou University
Solid State Phenomena | Year: 2012

Upon the 325 nm excitation from a helium-cadmium laser, the photoluminescence (PL) from aged porous silicon was investigated with fluorescence spectroscopy. Each PL spectrum of the aged porous silicon films contained two luminescent bands, one of the luminescent bands peaked at about 466.7 nm whereas the other luminescent band peaked at about 596.1 nm. The origin of the blue PL from aged porous silicon was discussed, and our results indicated that the blue photoluminescence of porous silicon films originated from the silicon oxide itself. © (2012) Trans Tech Publications, Switzerland.


Liu C.,Hubei University | Li Y.,South China University of Technology | Li Y.,Hubei University | Yang C.,Hubei University | And 3 more authors.
Chemistry of Materials | Year: 2013

A series of multibranched oligofluorenes with a phosphine oxide center were designed and synthesized through Suzuki cross-coupling reaction. Their thermal, photophysical, and electrochemical properties were investigated. The phosphine oxide linkage can disrupt the conjugation, and then allow the molecule system to extend to improve the solution processability and photoluminescent quantum yields without depreciating the deep blue emission. The noncoplanar molecular structures resulting from the phosphine oxide triangular pyramidal configuration can suppress the intermolecular interaction. All compounds display strong deep-blue emission both in solution and the solid state. Solution-processed devices based on these oligofluorenes exhibit highly efficient deep-blue electroluminescence, and the device performances are significantly enhanced with the extension of the oligofluorene branches. The double-layered device featuring PPO-TF3 as emitter shows a maximum current efficiency of 1.88 cd A-1 and a maximum external quantum efficiency of 3.39% with Commission Internationale de l′Eclairage (CIE) coordinates of (0.16, 0.09) that are very close to the National Television Standards Committee's blue standard. © 2013 American Chemical Society.


Wang Q.,Hubei University | Huang W.,Hubei University | Yuan H.,Hubei University | Cai Q.,Hubei University | And 3 more authors.
Journal of the American Chemical Society | Year: 2014

Asymmetric hydrogenation of tetrasubtitued α-acetoxy β-enamido esters with rhodium catalysts based on chiral diphosphine ligands provides an efficient and concise route to the synthesis of chiral α-hydroxyl-β-amino acid derivatives in excellent enantioselectivities. The products are valuable chiral building blocks in many biologically active compounds and have important applications in organic synthesis. © 2014 American Chemical Society.


Zhu L.,Hubei University | Zhu L.,Saint Louis University | Zhou X.,China Earthquake Administration
Physics and Chemistry of the Earth | Year: 2016

Source inversion of small-magnitude events such as aftershocks or mine collapses requires use of relatively high frequency seismic waveforms which are strongly affected by small-scale heterogeneities in the crust. In this study, we developed a new inversion method called gCAP3D for determining general moment tensor of a seismic source using Green's functions of 3D models. It inherits the advantageous features of the “Cut-and-Paste” (CAP) method to break a full seismogram into the Pnl and surface-wave segments and to allow time shift between observed and predicted waveforms. It uses grid search for 5 source parameters (relative strengths of the isotropic and compensated-linear-vector-dipole components and the strike, dip, and rake of the double-couple component) that minimize the waveform misfit. The scalar moment is estimated using the ratio of L2 norms of the data and synthetics. Focal depth can also be determined by repeating the inversion at different depths. We applied gCAP3D to the 2013 Ms 7.0 Lushan earthquake and its aftershocks using a 3D crustal-upper mantle velocity model derived from ambient noise tomography in the region. We first relocated the events using the double-difference method. We then used the finite-differences method and reciprocity principle to calculate Green's functions of the 3D model for 20 permanent broadband seismic stations within 200 km from the source region. We obtained moment tensors of the mainshock and 74 aftershocks ranging from Mw 5.2 to 3.4. The results show that the Lushan earthquake is a reverse faulting at a depth of 13–15 km on a plane dipping 40–47° to N46° W. Most of the aftershocks occurred off the main rupture plane and have similar focal mechanisms to the mainshock's, except in the proximity of the mainshock where the aftershocks' focal mechanisms display some variations. © 2016 Elsevier Ltd


Chen Y.F.,Hubei University
Advanced Materials Research | Year: 2014

The merits of HVDC, such as long-distance power transmission, less line lose,ability to transmit high-power and so on,were introduced. The obstacles in development of HVDC,including failure of commutation,hazards of higher harmonics,limitations of transmission direction, problems of insulation and so on,were analyzed. The research progress both at home and abroad in development of HVDC were summarized. At last,research and application prospects of HVDC were prospected briefly. © (2014) Trans Tech Publications, Switzerland.


Tang Y.,Hubei University | Li L.,Hubei University | Li X.,CAS Xi'an Institute of Optics and Precision Mechanic
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics | Year: 2011

In the field of machine learning, it is a key issue to learn and represent similarity. This paper focuses on the problem of learning similarity with a multikernel method. Motivated by geometric intuition and computability, similarity between patterns is proposed to be measured by their included angle in a kernel-induced Hilbert space. Having noticed that the cosine of such an included angle can be represented by a normalized kernel, it can be said that the task of learning similarity is equivalent to learning an appropriate normalized kernel. In addition, an error bound is also established for learning similarity with the multikernel method. Based on this bound, a boosting-style algorithm is developed. The preliminary experiments validate the effectiveness of the algorithm for learning similarity. © 2010 IEEE.


Hu X.,Huazhong University of Science and Technology | Zeng M.,Hubei University | Wang A.,Huazhong University of Science and Technology | Zhu L.,Huazhong University of Science and Technology | And 2 more authors.
Optics Express | Year: 2015

We fabricate a nonlinear optical device based on a fiber pigtail cross-section coated with a single-layer graphene grown by chemical vapor deposition (CVD) method. Using such graphene-assisted nonlinear optical device, we experimentally demonstrate tunable wavelength conversion of a 10 Gbaud quadrature phase-shift keying (QPSK) signal by exploiting degenerate four-wave mixing (FWM) progress in graphene. We study the conversion efficiency as functions of the pump power and pump wavelength and evaluate the bit-error rate (BER) performance. The observed optical signal-to-noise ratio (OSNR) penalties for tunable QPSK wavelength conversion are less than 2.2 dB at a BER of 1 × 10-3. © 2015 Optical Society of America.


Hu B.Q.,Wuhan University | Hu B.Q.,Hubei University
Knowledge-Based Systems | Year: 2016

Three-way decisions on three-way decision spaces are based on fuzzy lattices, i.e. complete distributive lattices with involutive negators. However, now some popular structures, such as hesitant fuzzy sets and type-2 fuzzy sets, do not constitute fuzzy lattices. It limits applications of the theory of three-way decision spaces. So this paper attempts to generalize measurement on decision conclusion in three-way decision spaces from fuzzy lattices to partially ordered sets. First three-way decision spaces and three-way decisions are discussed based on general partially ordered sets. Then this paper points out that the collection of non-empty subset of [0, 1] and the family of hesitant fuzzy sets are both partially ordered sets. Finally this paper systematically discusses three-way decision spaces and three-way decisions based on hesitant fuzzy sets and interval-valued hesitant fuzzy sets and obtains many useful decision evaluation functions. © 2015 Elsevier B.V. All rights reserved.


Ma C.,Hubei University | Chen H.,Hubei University | Sun N.,Hubei University | Ye Y.,Hubei University
Food Analytical Methods | Year: 2012

A molecularly imprinted polymer (MIP) monolith has been prepared and characterized. Its application to the assay of thiamphenicol in milk with high-performance liquid chromatography-photodiodes array detector was validated. The newly developed MIP monolith was produced using an analogue to thiamphenicol as the template molecule to avoid major traditional drawback associated with MIPs of residual template bleeding. The MIP monolith synthesized in a micropipette tip could be connected with syringes in different sizes simply to perform solid-phase microextraction process without any other treatment. This molecularly imprinted polymer monolith microextraction (MIPMME) method showed high selectivity and enrichment ability for thiamphenicol (TAP). Several parameters affecting MIPMME were investigated, including the flow rate, volume, pH and salt concentration of sample, the type and volume of washing solution, and the type and flow rate of eluent. The recovery of this method for TAP was investigated and high recoveries of 93. 5 ~ 96. 8% from milk were obtained with relative standard deviations less than 6. 3%. © 2012 Springer Science+Business Media, LLC.


Liu X.,Hubei University
Applied Mechanics and Materials | Year: 2014

As the third Generation mobile communication technology develops quickly, all sorts of smartphone development platform are constantly launched, including Google's Android mobile phone, and the promising future of Android cannot be ignored. Allow for the situation, the design and implementation of the Video on Demand System based on Android has realistic significance. Our article mainly states the development of Android Video on Demand application, JAVA service application and network communication. Summarize the principle of VOD system and draw flow-process diagram of it. We develop VOD application using JAVA language on Android which is based on the flow-process diagram successfully. Finally, debugging the programming on a Google's Android mobile phone, finding the bugs existing in the program and modify the mistakes to improve the software. My paper concluded the framework of VOD system on Android and verified it's availability by realizing it on a Android cellphone to provide a model for future VOD system. © (2014) Trans Tech Publications, Switzerland.


In this study, the overall property of fiber reinforced polymer (FRP) was researched. It is currently widely used in all areas, mainly in civil engineering. The huge need of this material drives the research of its mechanical property and corrosion mechanism. It is proven that the FRP can significantly strengthen the whole structure due to the support of fiber. And by applying osmosis hypothesis into the explanation of corrosion of FRP, we concluded that its corrosion rate is much slower than common materials, like steel. Generally, based on these conclusions, FRP is suitable for most of the facilities in civil engineering. © 2014 IFSA Publishing, S. L.


Zou Y.,Hubei University | Zhang Y.H.,Hubei University | He P.X.,Hubei University
Designed Monomers and Polymers | Year: 2013

Amphoteric terpolymers composed of acrylamide, 2-methylacryloylxyethyl trimethyl ammonium chloride, and 2-acrylamido- 2-methyl-1-propane sulfonate were prepared via free-radical polymerization in aqueous solution of ammonium sulfate (AS), using poly(2-methylacryloylxyethyl trimethyl ammonium chloride) as stabilizer to yield terpolymers with random distributions. The particle size of the synthesized amphoteric polyacrylamide (AmPAM) ranged from 1 to 8 μm and the intrinsic viscosity ranged from 5.6 to 14.2 dL/g. The influences of aqueous solution of AS concentration, stabilizer concentration, initiator concentration, monomer concentration on the conversion of monomer, the intrinsic viscosity, and the particle size were systematically investigated. The characteristic of amphoteric polymer was also be studied. Throughout the study, we found that the isoelectric point of the amphoteric polyelectrolyte we synthesized is about 7. With the increase in sodium chloride, the reduced viscosity of AmPAM increased. Among the different type of inorganic salt, the degree of influence of anionic is I > Br > Cl. Copyright © 2013 Taylor & Francis.


He W.,Wuhan University | Qian J.,Hubei University | Cao Y.,Wuhan University | Ai X.,Hubei University | Yang H.,Hubei University
RSC Advances | Year: 2012

Layered Li[Li 0.2Co 0.13Ni 0.13Mn 0.54]O 2 nanoparticles were synthesized by a simple polymer-pyrolysis method and then coated with 3 wt% Al 2O 3 to form a ∼4 nm thick protective skin. The Al 2O 3-coated Li[Li 0.2Co 0.13Ni 0.13Mn 0.54]O 2 electrode demonstrates a high initial coulombic efficiency of 96.1%, a large reversible capacity of ∼311 mAh g -1, and a good cyclability with 83.8% capacity retention after 70 cycles. Particularly, this material can deliver a quite high capacity of ∼239 mAh g -1 at a high rate of 400 mA g -1. This superior electrochemical performance results from the well-crystallized nanocores and effective surface modification of the material. The former provides a short diffusion path and fast transport channels for lithium ion insertion/extraction reactions and the latter restrains the elimination of oxide ion vacancies and metal ion rearrangement during charge-discharge cycling. Due to their simplicity and applicability, the synthetic method along with the surface modification technique is easily adopted to make high performance xLi 2MnO 3·(1 - x)LiMO 2 materials for practical battery applications. © 2012 The Royal Society of Chemistry.


Du H.-N.,Hubei University
Current Protein and Peptide Science | Year: 2012

Myriad covalent post-translational modifications of histones have been demonstrated to play crucial roles in regulating gene transcription, gene repression, DNA damage and repair, and beyond. It has been long known that these modifications are often dynamic, such as histone ubiquitination and deubiquitination, and the processes through adding and/or removing these modified marks catalyzed by various classes of enzymes commonly influence many important physiological functions. In recent few years, studies on histone ubiquitination re-garners much attention arising from lots of new exciting findings emerged. Several important histone ubiquitination sites have been mapped in different organisms. In addition, the identification and characterization of numerous ubiquitin modifying enzymes, especially ligases and deubiquitinases, have facilitated the progress in understanding the roles of histone ubiquitination/deubiquitination events. Of particular interest, histone ubiquitination interplays with many other chromatin modifications, namely "crosstalk", which contributes to a variety of cellular events. In this review, I summarize the enzymes and factors involved in regulating the attachment and removal of ubiquitin from histones, and focus on what essential roles this modification plays. I also present new evidence that links histone ubiquitination with other histone modifications, which comprises an intricate crosstalk network. © 2012 Bentham Science Publishers.


Lou X.,Hubei University | Mu H.,Hubei University | Gong R.,Hubei University | Fu E.,Hubei University | And 2 more authors.
Analyst | Year: 2011

By utilizing a displacement method, a macrocyclic compound 1, could report the presence of sulfide anion, with the detection limit of 7.0 × 10 -7 mol/L; moreover, no interference was observed from other anions, including SO3 2-, HSO3 -, SO 4 2-, ClO4 -, I-, Br -, Cl-, F-, IO3 -, HPO4 2-, PO4 3-, C2O 4 2-, S2O3 2-, CO 3 2-, AcO-, CN- and P 2O7 4-, making compound 1 a new, highly sensitive and selective sulfide anion chemosensor. © The Royal Society of Chemistry 2011.


Ma Q.-L.,Changzhou University | Xiong R.,Hubei University | Ming Huang Y.,Changzhou University
Solid State Phenomena | Year: 2012

A typical liquid crystal (LC) N,N-(terephthalylidene) bis(4- decylbenzenamine) (TB10A) was firstly synthesized at room temperature. The synthesized LC TB10A were investigated by differential scanning calorimetry (DSC), polarizing optical microscopy (POM), ultraviolet-visible (UV-vis) spectrophotometry, photoluminecence (PL) spectroscopy and electronic structure calculations. Upon the 325 nm excitation, the dilute tetrahydrofuran solutions of TB10A could give off blue PL. With Huckel tight-binding method, the electronic structures of the TB10A were calculated. Our results demonstrated that the deep-blue PL observed at about 489 nm (2.54 eV) can be assigned to the φ* → n transition for the TB10A. © (2012) Trans Tech Publications, Switzerland.


Shu H.,Hubei University | Cao L.,Hubei University | Chang G.,Hubei University | He H.,Hubei University | And 2 more authors.
Electrochimica Acta | Year: 2014

Dendrite-like gold nanostructures (DGNs) were directly electrodeposited onto the surface of a glassy carbon electrode (GCE) via the potentiostatic method without any templates, surfactants, or stabilizers. The effects of the deposition time, potential and the concentration of precursor solution on the evolution of the nanostructure and on the electrocatalytic activity of the DGNs were systematically investigated using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and electrochemical methods including cyclic voltammetry, linear voltammetry and chronoamperometry. The results confirmed that DGNs have good electrocatalytic activity towards the electro-oxidation of glucose in a neutral phosphate buffer solution (PBS, pH 7.4). A non-enzymatic glucose sensor fabricated with the DGNs as an electrocatalyst showed a quick response (less than 2 s), a low detection limit (0.05 mM), a wide and valuable linear range (0.1 - 25 mM), a high sensitivity (190.7 μA cm-2 mM-1) and good repeatability and stability. In addition, the commonly interfering species, such as ascorbic acid (AA), uric acid (UA), and 4-acetaminophen (AP), did not cause obvious interference because of the use of a low detection potential (0.15 V vs. Ag/AgCl). This work demonstrates a simple and an effective sensing platform for the non-enzymatic detection of glucose. © 2014 Elsevier Ltd.


Yuan D.,Wuhan University | Hu X.,Hubei University | Qian J.,Hubei University | Pei F.,Jiangxi Electric Power Research Institute | And 5 more authors.
Electrochimica Acta | Year: 2014

Na0.67Mn0.65Fe0.35-xNixO 2 as a Na storage cathode material was prepared by a sol-gel method. The XRD measurement demonstrated that these samples have a pure P2 phase. The charging/discharging tests exhibit that the Na0.67Mn 0.65Fe0.35O2 electrode has a high initial capacity of 204 mAh g-1 with a slow capacity decay to 136 mAh g -1, showing higher capacity and considerable cycling performance. When partially substituting Ni for Fe, the Na0.67Mn 0.65Fe0.2Ni0.15O2 electrode exhibits higher reversible capacity of 208 mAh g-1 and improved cycling stability with 71% capacity retention over 50 cycles. The greatly improved electrochemical performance for the Na0.67Mn0.65Fe 0.2Ni0.15O2 electrode apparently belongs to the contribution of the Ni substitution, which facilitates to improve the electrochemical reversibility of the electrode and alleviate the Jahn-Teller distortion of Mn(III). Therefore, the Ni-substituted Na0.67Mn 0.65Fe0.2Ni0.15O2 possibly serves as a promising high capacity and stable cathode material for sodium ion battery applications. © 2013 Elsevier Ltd. All rights reserved.


Zhang S.,Hubei University | Shi Z.,Hubei University | Wang J.,Hubei University | Cheng Q.,Huazhong University of Science and Technology | Wu K.,Huazhong University of Science and Technology
Electrochimica Acta | Year: 2014

Polystyrene microspheres with diameter of 350 nm were prepared, and then used to arrange on the surface of glassy carbon electrode (GCE) as structure-directing template. By successive cyclic sweeps between -1.0 V and 2.0 V in pH 7 phosphate buffer containing 10 mM cysteine, polycysteine film was electrodeposited on polystyrene microspheres-arranged GCE. After removing polystyrene template, a three-dimensionally ordered macroporous (3-DOM) polycysteine film was achieved, as confirmed by scanning electron microscopy measurements. Electrochemical responses of K3[Fe(CN)6] probe indicated that 3-DOM polycysteine film-modified GCE exhibited larger active area, compared with GCE, polycysteine film-modified GCE and electrochemically oxidized GCE. The application of 3-DOM polycysteine film in electrochemical detection of 4-chlorophenol was studied. Due to ordered porous structures, the 3-DOM polycysteine film-modified GCE displayed signal enhancement effects, and enhanced the oxidation peak currents of 4-chlorophenol. As a result, a sensitive electrochemical method was developed for the detection of 4-chlorophenol, and the detection limit was 1.67 × 10-8 M. This new method was used to detect 4-chlorophenol in water samples, and the value of recovery was over the range from 99.6% to 107%. © 2014 Elsevier Ltd.


Zhang Q.,Hubei University | Liu Y.,Hubei University | Chen S.,Hubei University
Journal of Electroanalytical Chemistry | Year: 2013

DFT calculations are combined with thermodynamic and kinetic modeling to study the effect of temperature on the electrochemical adsorption of hydrogen and the exchange current density (j0) of the hydrogen electrode reactions (HERs) on Pt(111). The nature of the underpotential and overpotential deposited hydrogen (UPD H and OPD H), the potential dependence of their coverage and the corresponding voltammetric curves for hydrogen adsorption are evaluated for temperatures from 273 K to 373 K. By introducing a coverage-dependent correction term in the free energy expression to account for the effect of the interaction between hydrogen ad-atoms on the configurational entropy, the DFT calculations give isotherms and voltammetric curves for hydrogen adsorption agreeing reasonably with those observed in experiments. It is shown that both the UPD and OPD H on Pt(111) surface could be the H atoms adsorbed at the 3-fold fcc hollow sites. A linear dependence of lnj0 on T-1 is found under temperatures from 273 K to 373 K, which, however, deviates from that predicted by the Arrhenius relation. The values of j0 and activation enthalpy for HERs on Pt(111) surface are estimated. © 2012 Elsevier B.V. All rights reserved.


Wang B.,Hubei University | Wang B.,CAS Lanzhou Institute of Chemical Physics | Zhang Y.,Hubei University | Zhang Y.,CAS Lanzhou Institute of Chemical Physics | And 4 more authors.
Journal of Materials Chemistry | Year: 2012

The underlying theories interpreting wetting phenomena are still mainly focused on the Young's equation, the Wenzel equation, and the Cassie-Baxter equation, despite the fact that wetting phenomena have been studied over the past decades. Based on these theories, people have understood that both surface chemical composition and its morphology can influence the contact angle of liquid droplets on solid surfaces. However, such equations are not sufficient to thoroughly explain the mechanisms of wetting phenomena, although they are still necessary. In this feature article, we review the theory, from the classical wetting models to the most recent theoretical advances, of superhydrophobic surfaces with regard to the wetting process, and some promising breakthroughs in the advance of the theory are proposed in the final section. © 2012 The Royal Society of Chemistry.


Li J.,Hubei University | Zhuang X.,Hubei University | Querol X.,CSIC - Institute of Environmental Assessment And Water Research
Fuel | Year: 2011

The Lincang (Yunnan Province, Southwest China) and Wulantuga (Inner Mongolia, Northeast China) coal deposits are known because of the high-Ge content. These coals have also a high concentration of a number of other elements. To determine the mode of occurrence of the enriched elements in both coals, six density fractions from <1.43 to >2.8 g/cm3 were obtained from two representative samples using heavy-liquids. A number of peculiar geochemical patterns characterize these high-Ge coals. Thus, the results of the chemical analysis of these density fractions showed that both coals (very distant and of a different geological age) are highly enriched (compared with the usual worldwide coal concentration ranges) in Ge, As, Sb, W, Be, and Tl. This may be due to similar geochemistry of hydrothermal fluids influencing the Earth Crust in these regions of China. Moreover, Wulantuga coal (Early Cretaceous subbituminous coal) is also enriched in Ca, Mg, and Na, and Lincang coal (Neogene subbituminous coal) in K, Rb, Nb, Mo, Sn, Cs, and U. A group of elements consisting of Ge, W, B, Nb, and Sb mostly occur with an organic affinity in both coals. Additionally, Be, U, and Mo (and partially Mn and Zn) in Lincang, and Na and Mg in Wulantuga occur also with a major organic affinity. Both coals have sulfide-arsenide mineral assemblages (Fe, S, As, Sn, and Pb, and in addition to Tl, Ta, and Cs in the Lincang coal). The occurrence of Al, P, Li, Sc, Ti, V, Cr, and Zr in both coals, and Ba in Lincang, are associated with the mineral assemblage of silico-aluminates and minor heavy minerals. Furthermore, P, Na, Li, Sc, Ti, Ga, Rb, Zr, Cr, Ba, Th, and LREE (La, Ce, Pr, Nd, and Gd) in Lincang are associated with mineral assemblages of phosphates and minor heavy minerals. The two later mineral assemblages are derived from the occurrence of detrital minerals. Finally, the two coal samples have also the sulfate mineral assemblage (Ca and Sr) that probably occur as a consequence of a diagenetic oxidation and alteration of the coal seams. The enrichment of Ge in coal occurred when the organic matter was still reactive to trap Ge, but several features indicate that the enrichment was diagenetic. © 2010 Elsevier Ltd. All rights reserved.


Deng C.-H.,Hubei University | Zhang Q.-P.,Hubei University
Chinese Medical Journal | Year: 2010

Objective To review the central role of leukemia stem cells (LSCs) in drug resistance and metastasis, aiming to provide key insights into leukemogenic pathology and developing novel therapeutic strategies against the relapse of leukemia. Data sources The data used in this review were obtained mainly from the studies reported in PubMed using the key terms "tumor-initiating cells", "leukemia stem cells", "drug resistance" and "metastasis". Study selection Relevant articles on studies of leukemia stem cells were selected. Results Increasing numbers of studies have suggested the importance of cancer stem cells (CSCs) in the initiation and maintenance of cancer, especially in leukemia. This review has summarized the origin, characteristics, isolation and identification of LSCs. It highlights the crucial role of LSCs in drug resistance and metastasis of leukemia by illustrating possible mechanisms and aims to provide novel therapeutic strategies for LSCs-targeted treatment. Conclusion LSCs play a crucial role in drug resistance and metastasis of leukemia and new promising LSCs-targeted therapies warrant investigation in both experimental models and clinical practice.


Liang C.,Hubei University
Zhongguo zhen jiu = Chinese acupuncture & moxibustion | Year: 2010

To probe a better therapy for chronic persistent asthma. Thirty-six cases of chronic persistent asthma were randomly divided into a beat-sensitive moxibustion group (17 cases) and a western medication group (19 cases). In heat-sensitive moxibustion group, the sensitization points between Feishu (BL 13) and Geshu (BL 17) were selected with heat-sensitive moxibustion; in western medication group, Seretide inhalant was applied. The patients of both groups were continuously treated for 3 months and the therapeutic effects were evaluated by clinical symptom scores and pulmonary ventilation function test. After treatment, the effective rate of 88.2% (15/17) in heat-sensitive moxibustion group was superior to that of 47.4% (9/19) in western medication group (P < 0.05); the clinical symptom scores and pulmonary ventilation function were obviously improved in the two groups, and the heat-sensitive moxibustion group was superior to the western medication group (all P < 0.05). For chronic persistent bronchial asthma, heat-sensitive moxibustion can improve the clinical symptoms and the pulmonary ventilation function, and it is better than Seretide inhalant.


Hu D.-H.,Hubei University
19th International Conference on Industrial Engineering and Engineering Management: Engineering Economics Management | Year: 2013

This paper aims to explore what the organizational routines are, how organizational routines form and change, as well as theirs effect to performance feedback. The paper also tells how organization performance feedback affects organizational routines from the individual, job team, and organizational level. It points that organizational routines help to improve enterprise performance, however, the organizational routines need adjust according to change of organizational environment, and the positive effect could be lasting only in this way. © Springer-Verlag Berlin Heidelberg 2013.


Yang X.,Hubei University | Zhang S.,Hubei University | Pang X.,Hubei University | Fan M.,Hubei University
Journal of Cellular Biochemistry | Year: 2012

Postnatal dental pulp stem cells (DPSCs) represent a unique precursor population in the dental pulp, which have multipotential and harbor great potential for tissue engineering purposes. However, for therapy applications, transplanted cells are often exposed to unfavorable conditions such as cytokines released from necrotic or inflammatory cells in injured tissues. It is not clear how stem cells exposed to these conditions changes in their characteristics. In this study, the effects of pro-inflammatory cytokines, such as IL-1 and TNF, on DPSCs were investigated. Cells were treated with IL-1, TNF, or both for 3, 7, and 12 days. The cultures were evaluated for cell proliferation, ALP activity, and real-time PCR. We found that a short treatment (3 days) of pro-inflammatory cytokines induced the odontogenic differentiation of DPSCs. Furthermore, post 3 days treatment with pro-inflammatory cytokines, the cell-scaffold complexes were implanted subcutaneously in mice for 8 weeks. Histological analysis demonstrated that the cultures gave obviously mineralized tissue formation, especially for both IL-1 and TNF applied. These data suggest that IL-1 and TNF produced in the early inflammatory reaction may induce the mineralization of DPSCs. © 2011 Wiley Periodicals, Inc.


Mao Y.,Hubei University | Luick J.L.,South Australian Research And Development Institute
Journal of Geophysical Research: Oceans | Year: 2014

New mechanisms for stratification and upwelling in the southern Great Barrier Reef (GBR) are identified, and dynamic details of Capricorn Eddy, a transient feature located off the shelf at the southern extremity of the GBR, are revealed using the newly available surface current from High Frequency (HF) radar combined with other remote sensing and mooring data. The HF radar surface currents were used for tidal harmonic analysis and current-wind correlation analysis. These analyses, combined with Sea Surface Temperature (SST) data, mooring data, and altimetry-based geostrophic currents, enabled the effects of forcing from the large-scale oceanic currents (including the East Australian Current (EAC)), wind, and tides in a topographically complex flow regime to be separately identified. Within the indentation region where the width of the shelf abruptly narrows, current is strongly coupled with the EAC. Here strong residual flows, identified on current maps and SST images, fall into three patterns: southward flow, northwestward flow, and an eddy. Multiple data sets shed light on the prerequisite for the formation of the eddy, the reasons for its geometric variation, and its evolution with time. Intrusions of the eddy onto the shelf result in stratification characterized by a significant increase of surface temperature. Upwelling driven by wind or oceanic inflow is shown to cause stratification of previously well-mixed shelf water. The upwelling appears to be associated with equatorward-traveling coastal-trapped waves. The integrative method of analysis embodied here is applicable to other coastal regions with complex circulation. Key Points New mechanisms for stratification and upwelling in the SGBR are identified Detailed properties of the Capricorn Eddy are observed The integrative method is powerful in studying complex coastal circulation © 2014. American Geophysical Union. All Rights Reserved.


Gong Y.,Hubei University
Information Systems Frontiers | Year: 2016

Crowdsourcing has become an increasingly attractive practice for companies to abstain on-demand workforce and higher level of flexibility in open contexts. While knowledge-intensive crowdsourcing is expected to be prosperous, most current crowdsourcing calls are still about general and low-priced tasks. An obstacle of conducing knowledge-intensive crowdsourcing is the lack of diversity of expertise and the small scale of crowd in isolated crowdsourcing marketplaces. In this paper, a network of crowdsourcing marketplaces is envisioned for efficient knowledge-intensive crowdsourcing and engagement of massive and diverse participants across different marketplaces. Based on an algorithm for estimating participants for knowledge-intensive crowdsourcing tasks, an experiment with 100 simulations indicates that conducting crowdsourcing tasks in a network of crowdsourcing marketplaces results in higher customer satisfaction than doing that in isolated marketplaces. This finding advocates the development of a network of crowdsourcing marketplaces to open up the potential of knowledge-intensive crowdsourcing. © 2016 Springer Science+Business Media New York


Gan W.,Hubei University
Zhonghua nan ke xue = National journal of andrology | Year: 2011

To evaluate the efficacy and safety of Tolterodine Tartrate combined with the alpha-receptor blocker in the treatment of benign prostatic hyperplasia with detrusor overactivity (BPH-DO). A total of 113 patients with BPH-DO were randomly assigned to receive Tolterodine Tartrate combined with Cardura (Group A) and Cardura alone (Group B), both for 12 weeks. Then we recorded and compared their average 24 h urinary frequency, IPSS and QOL score, maximum urinary flow rate, residual urine volume and urinary retention times before and after the treatment. After the treatment, Group A showed significantly better improvement in the average 24 h urinary frequency and scores on IPSS and QOL than Group B. No significant differences were found between the two groups in the maximum urinary flow rate and residual urine volume. No acute urinary retention occurred in either group. The combined use of Tolterodine Tartrate and the alpha-receptor blocker can effectively relieve the symptoms of dysuria, urinary frequency and urinary urgency in patients with BPH-DO, with neither significant adverse effects on the maximum flow rate and residual urine volume nor increase in the incidence of acute urinary retention.


Wang L.,Hubei University | Zhou G.,Hubei University
Advanced Materials Research | Year: 2013

Data aggregation is the important method to reduce data traffic and lower energy expenditure in wireless sensor networks (WSN). This paper analyzes the characteristics of data sampled by nodes, and gives the method to decide spatial correlation between neighboring nodes and the criteria to classify and decide data in WSN. On the basis of this, this paper proposes a spatial correlation based data aggregation algorithm for WSN, SCBD. SCBD classifies and decides data according to data criteria and spatial correlation among nodes in normal nodes and cluster heads at the same time, and then aggregates different types of data. The results show that SCBD outperforms RAA in terms of energy consumption, rate of data detection and quality of data aggregation. © (2013) Trans Tech Publications, Switzerland.


Tang H.T.,Hubei University
Zhongguo zhen jiu = Chinese acupuncture & moxibustion | Year: 2011

To observe the correlation relationship between acupuncture at Dicang (ST 4), Hegu (LI 4) and Houxi (SI 3) on the affected side of peripheral facial paralysis patients and activated areas in brain functional areas and central regulation mechanism of acupuncture at Hegu (LI 4) treatment. Eighteen cases with left peripheral facial paralysis were randomly divided into a Hegu group, a Dicang group and a Houxi group, 6 cases in each group. They were treated with electroacupuncture at left Dicang (ST 4), Hegu (LI 4) and Houxi (SI 3), respectively, and were examined with fMRI covering the whole brain at the same time. The fMRI data was analyzed by SPM software. It was found that the left precentral gyrus area and the left postcentral gyrus area were activated when electroacupuncture at left Hegu (LI 4), and the right precentral gyrus area and the bilateral postcentral gyrus area were activated when electroacupuncture at left Dicang (ST 4), and there was no activated area at precentral gyrus area and post central gyrus area when electroacupuncture at left Houxi (SI 3). The sensory importation information from Hegu (LI 4) and Dicang (ST 4) can converge and coincide in the brain and may influence each other.


Zheng Y.,Hubei University
Lecture Notes in Electrical Engineering | Year: 2013

In this paper, we put forward an intrusion detection method based on k-means algorithm in accordance with the existing network intrusion detection problem. As can be seen from experimental result, the use of algorithm can be effectively separated normal and abnormal data. The application of k-means algorithm is feasible and effective. © 2013 Springer Science+Business Media.


Zhang H.,Hubei Engineering University | Zhang L.,Hubei Engineering University | Shen H.,Hubei University
Signal Processing | Year: 2012

The spatial resolution of a hyperspectral image is often coarse because of the limitations of the imaging hardware. Super-resolution reconstruction (SRR) is a promising signal post-processing technique for hyperspectral image resolution enhancement. This paper proposes a maximum a posteriori (MAP) based multi-frame super-resolution algorithm for hyperspectral images. Principal component analysis (PCA) is utilized in both parts of the proposed algorithm: motion estimation and image reconstruction. A simultaneous motion estimation method with the first few principal components, which contain most of the information of a hyperspectral image, is proposed to reduce computational load and improve motion field accuracy. In the image reconstruction part, different image resolution enhancement techniques are applied to different groups of components, to reduce computational load and simultaneously remove noise. The proposed algorithm is tested on both synthetic images and real image sequences. The experimental results and comparative analyses verify the effectiveness of this algorithm. © 2012 Elsevier B.V. All rights reserved.


Wu S.,Hubei University | Weng Z.,Hubei University | Liu X.,Hubei University | Yeung K.W.K.,University of Hong Kong | Chu P.K.,City University of Hong Kong
Advanced Functional Materials | Year: 2014

As baby boomers age, diabetes mellitus, cancer, osteoarthritis, cardiovascular diseases, and orthopedic disorders are more widespread and the demand for better biomedical devices and functional biomaterials is increasing rapidly. Owing to the good biocompatibility, chemical stability, catalytic efficiency, plasticity, mechanical properties, as well as strength-to-weight ratio, titanium dioxide (TiO2) based nanostructured materials are playing important roles in tissue reconstruction and diagnosis of these diseases. Here, recent advance in the research of nanostructured TiO2 based biomaterials pertaining to bone tissue engineering, intravascular stents, drug delivery systems, and biosensors is described. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Li Q.,Hubei University | Shi J.,Hubei University | Li H.,Hubei University | Li S.,Hubei University | And 6 more authors.
Journal of Materials Chemistry | Year: 2012

A series of "H" type dye sensitizers with pyrrole as the conjugated bridge were synthesized, in which two pieces of N-arylpyrrole-based organic dye moieties were linked together through various aromatic rings. Interestingly, the introduced aromatic isolation group not only gave a new possibility to modify the construction structure, but also controlled the topological structure of the resultant dyes in some degree. As a result, their performance could be adjusted, and the configuration of "H"-type could suppress the aggregations on the TiO 2 surface. The performance of the DSCs based on these dyes as the sensitizers demonstrated that the structure of these dyes was beneficial to the devices, and the conversion efficiency of the solar cell based on dye LI-22 with carbazole as the isolation group was as high as 5.22%. © The Royal Society of Chemistry 2012.


Tang S.,Hubei University | Yuan J.,Hubei University | Liu C.,Hubei University | Lei A.,Hubei University | Lei A.,CAS Lanzhou Institute of Chemical Physics
Dalton Transactions | Year: 2014

Esterification is a fundamental transformation in chemistry. Traditional esterification only largely occurs between carboxylic acid derivatives and alcohols, and often involves multistep processes. Developments in the transition-metal-catalysed and metal-free direct esterification of alcohols under oxidative conditions has opened a door to the efficient, sustainable and environmentally friendly synthesis of esters from readily available materials. This Perspective gives an overview which covers the recent development of this emerging field. © the Partner Organisations 2014.


Fan C.,Hubei University | Yang C.,Hubei University
Chemical Society Reviews | Year: 2014

Owing to the electron spin-orbit coupling (SOC) and fast intersystem crossing (ISC), heavy-metal complexes (such as iridium(iii), platinum(ii) and osmium(ii) complexes, etc.) are phosphorescent emitters at room temperature. Since 1998, heavy-metal complexes as phosphors have received considerable academic and industrial attention in the field of organic light-emitting diodes (OLEDs), because they can harvest both the singlet (25%) and triplet (75%) excitons for emission during the electro-generated processes. Among all the visible colors (blue, green, yellow, orange and red), the yellow/orange heavy-metal complexes play an important role for realizing full-color OLEDs as well as high-efficiency white OLEDs, and thus the development of highly efficient yellow/orange heavy-metal complexes is a pressing concern. In this article, we will review the progress on yellow/orange heavy-metal complexes as phosphors in OLEDs. The general principles and useful tactics for designing the yellow/orange heavy-metal complexes will be systematically summarized. The structure-property relationship and electrophosphorescence performance of the yellow/orange heavy-metal complexes in monochromatic phosphorescent OLEDs (PhOLEDs) and white OLEDs (WOLEDs) will be comprehensively surveyed and discussed. © The Royal Society of Chemistry 2014.


Yang Y.-K.,University of Sydney | Yang Y.-K.,Hubei University | He C.-E.,Hubei University | Peng R.-G.,Hubei University | And 5 more authors.
Journal of Materials Chemistry | Year: 2012

Chemical reduction of graphite oxide (GO) to produce graphene nanosheets often results in irreversible agglomeration and precipitation. Herein, stable well-dispersed graphene sheets in solvents were obtained by simultaneous functionalization and reduction of GO under alkaline conditions, in the presence of sodium borohydride and imidazolium ionic liquids (Imi-ILs) containing two vinyl-benzyl groups. In this case, positively charged imidazolium groups of Imi-ILs underwent ion-exchange with negatively charged GO sheets and were linked to their edges, while Imi-ILs were non-covalently attached onto the large surfaces of graphene through π-π and/or cation-π stacking interactions. The vinyl-benzyl reactive sites were then copolymerized in situ with methyl methacrylate to fabricate graphene/poly(methyl methacrylate) (PMMA) composites. Functionalized graphene sheets were uniformly dispersed in the PMMA matrix and contributed to large increases in storage modulus (+58.3%) and glass transition temperature (+19.2 °C) at 2.08 vol.% loading. High electrical conductivity was also achieved at graphene loading levels beyond 1 vol.% (ca. 2.55 Sm -1) with a low percolation threshold (0.25 vol.%) for the composites. Hence, a general methodology which facilitates the development of a multifunctional advanced material has been successfully established. This can be extended to other vinyl polymer-based composites containing graphene. © The Royal Society of Chemistry 2012.


This overview article gives a picture of multichannel analysis of high-frequency surface (Rayleigh and Love) waves developed mainly by research scientists at the Kansas Geological Survey, the University of Kansas and China University of Geosciences (Wuhan) during the last eighteen years by discussing dispersion imaging techniques, inversion systems, and real-world examples. Shear (S)-wave velocities of near-surface materials can be derived from inverting the dispersive phase velocities of high-frequency surface waves. Multichannel analysis of surface waves-MASW used phase information of high-frequency Rayleigh waves recorded on vertical component geophones to determine near-surface S-wave velocities. The differences between MASW results and direct borehole measurements are approximately 15% or less and random. Studies show that inversion with higher modes and the fundamental mode simultaneously can increase model resolution and an investigation depth. Multichannel analysis of Love waves-MALW used phase information of high-frequency Love waves recorded on horizontal (perpendicular to the direction of wave propagation) component geophones to determine S-wave velocities of shallow materials. Because of independence of compressional (P)-wave velocity, the MALW method has some attractive advantages, such as 1) Love-wave dispersion curves are simpler than Rayleigh wave's; 2) dispersion images of Love-wave energy have a higher signal to noise ratio and more focused than those generated from Rayleigh waves; and 3) inversion of Love-wave dispersion curves is less dependent on initial models and more stable than Rayleigh waves.To derive S-wave velocities of near-surface materials from high-frequency surface waves only utilizes their phase information. Feasibility of using their amplitude information to estimate near-surface quality factors (Qs and/or Qp) has been studied. Attenuation coefficients of high-frequency surface (Rayleigh and/or Love) waves can be calculated from their amplitude. And by inverting attenuation coefficients, it is feasible to obtain quality factors. Similar to inverting phase velocities of Love waves for S-wave velocities, attenuation coefficients of Love waves are independent of Qp, which makes inversion of attenuation coefficients of Love waves to estimate Qs simpler than that of Rayleigh waves.Both MASW and MALW methods to estimate near-surface S-wave velocities are non-invasive, non-destructive, environment-friendly, low-cost, fast, and in situ seismic methods and possess stable and efficient inversion algorithms to invert phase velocities of surface waves. Real world examples demonstrated that near-surface S-wave velocities derived from phase information are reliable and that methods discussed in the paper to estimate near-surface quality factors from amplitude information are feasible. © 2014 Elsevier B.V.


Lou X.,Hubei University | Zeng Q.,Hubei University | Zhang Y.,Hubei University | Wan Z.,Hubei University | And 2 more authors.
Journal of Materials Chemistry | Year: 2012

By dissolution of Au NPs, new polyacetylene-functionalized Au NPs were successfully developed as "turn-on" fluorescent probes for the detection of cyanide sensitively and selectively. The lowest concentration to quantify cyanide ions could be down to 3.0 × 10 -6 M, and other common anions including AcO -, Br -, C 2O 4 2-, Cl -, CO 3 2-, F -, HCO 3 -, NO 2 -, NO 3 -, PO 4 3-, S 2O 8 2-, SCN -, SO 3 2-, SO 4 2-, HPO 4 2-, and P 2O 7 4- had almost no influence. Furthermore, several real water samples spiked with cyanide, including local groundwater, tap water, boiled water, and lake water, were analyzed with RSD values less than 4%, and the experimental results demonstrated that our developed sensing system worked well in the above water samples. © The Royal Society of Chemistry 2012.


Wang H.,Hubei University | Wang T.,Hubei University | Wang X.,Hubei University | Liu R.,Hubei University | And 4 more authors.
Journal of Materials Chemistry | Year: 2012

A series of high-density double- and single-shelled ZnO/CdSe/CdTe, ZnO/CdTe/CdSe, ZnO/CdTe and ZnO/CdSe nanocable arrays were synthesized as photoanodes by an electrodeposition method using ZnO nanorod arrays as cores. For ZnO/CdSe/CdTe nanocable arrays, the uniform CdSe and CdTe nanoshells were composed of zinc-blende phase nanocrystals with a respective average size range of 10-20 nm and 7-15 nm, and formed a compact and continuous interface in between. Based on the band offset of the bulk material before contact and the interfacial Fermi level shift after contact, the energy level alignments at the CdSe/CdTe and CdTe/CdSe interface were deduced for the double-shelled nanocable arrays. The CdTe/CdSe interface of the ZnO/CdTe/CdSe nanocables has a negative band offset of -0.16 eV whilst for ZnO/CdSe/CdTe nanocables, the band edge of CdTe lies above CdSe with a conduction band offset of 0.16 eV at the CdSe/CdTe interface. Such a stepwise band alignment, together with the compact interface, fewer grain boundaries along the radial direction, and the fast transfer rate along the axial direction of the nanocables, makes the ZnO/CdSe/CdTe nanocable arrays photoanode have a saturated photocurrent of ∼14.3 mA cm -2. This is under the irradiation of AM1.5G simulated sunlight at 45 mW cm -2, which is greatly higher than ZnO/CdTe/CdSe, ZnO/CdSe or ZnO/CdTe nanocable arrays. © 2012 The Royal Society of Chemistry.


Huang J.,Hubei University | Sun N.,CAS Changchun Institute of Applied Chemistry | Yang J.,Hubei University | Tang R.,Hubei University | And 4 more authors.
Journal of Materials Chemistry | Year: 2012

In this paper, three benzene-cored fluorophors with TPE moiety peripheries (PhTPE, Ph2TPE and Ph3TPE), are synthesized and their thermal, optical and electronic properties are investigated. All of them are nearly non-emissive when readily dissolved in solution but become highly emissive in the aggregate state, making them promising candidates for optoelectronic materials. Non-doped OLEDs with these luminogens as emissive layers exhibit sky-blue to deep blue emissions from 488 to 457 nm with L max, η C, max and η P, max up to 3966 cd m -2, 5.0 cd A -1 and 3.87 lm W -1, respectively, owing to the twisted conformation between the benzene core and TPE units. © 2012 The Royal Society of Chemistry.


Gong S.,Hubei University | He X.,Hubei University | Chen Y.,CAS Changchun Institute of Applied Chemistry | Jiang Z.,Hubei University | And 4 more authors.
Journal of Materials Chemistry | Year: 2012

Two simple CBP isomers, namely m-CBP and o-CBP, were designed and synthesized by finely tuning the linking topology between the carbazole and the central biphenyl units of CBP, and their thermal, photophysical and electrochemical properties were investigated. Such simple modification of the linking topology endows the CBP isomers with high triplet energy and relative high thermal and morphological stability. The high triplet energies of m-CBP and o-CBP ensure efficient energy transfer from the host to the phosphor and triplet exciton confinement on the phosphor, as indicated by the transient photoluminescence decay of 3 wt% FIrpic doped into m-CBP and o-CBP. Blue phosphorescent devices employing FIrpic as guest and the two CBP isomers as hosts exhibit high efficiencies. The best EL performance is achieved for the o-CBP-based device, with a maximum current efficiency of 29.9 cd A -1, and a maximum external quantum efficiency of 14.2%, which are over 2 times higher than those of CBP. © 2012 The Royal Society of Chemistry.


Feng Q.,Hubei University | Algeo T.J.,Hubei University | Algeo T.J.,University of Cincinnati
Earth-Science Reviews | Year: 2014

The ~. 90% biodiversity loss among marine invertebrate species during the end-Permian mass extinction, the most severe Phanerozoic biocrisis, has been attributed to widespread oceanic anoxia ("superanoxia"). Recent studies of the lithofacies, inorganic geochemistry, and biomarkers of Permian-Triassic boundary (PTB) sections have yielded an inferred pattern of oceanic redox changes that is complex and sometimes inconsistent. In this contribution, we review the ecology of radiolarians, an important microzooplankton group during the Permo-Triassic transition, and consider its implications for contemporaneous changes in paleoceanographic conditions. Our analysis shows that (1) Late Permian radiolarian faunas were cosmopolitan with different orders having specific depth preferences, i.e., albaillellarians favoring deeper waters and spherical forms (entactinarians and spumellarians) shallower waters; (2) deep-water taxa declined earlier than shallow-water taxa; (3) many Paleozoic-type taxa survived into the Early Triassic but went extinct during a second crisis in the Dienerian ("dead clade walking"), followed by the appearance or expansion of Mesozoic-type taxa during the Olenekian; and (4) the survival of Paleozoic-type taxa during the Early Triassic was greater at higher paleolatitudes than in the tropics. These observations are consistent with a first-order redox control on radiolarian faunal distributions, specifically a shallowing and poleward expansion of the oceanic oxygen-minimum zone during the PTB crisis. The consequent adaptation of some deepwater taxa to shallower environments resulted in Early Triassic radiolarian faunas in continental basins becoming more similar to those in pelagic settings. Enhanced survival of Paleozoic-type taxa in high-latitude regions indicates that the main stressor on Permo-Triassic radiolarian communities was reduced oceanic oxygen levels (stronger in the tropics) rather than climatic warming (stronger at the poles). © 2014 Elsevier B.V.


Huang J.,Hubei University | Yang X.,Huazhong University of Science and Technology | Wang J.,Hubei University | Zhong C.,Hubei University | And 3 more authors.
Journal of Materials Chemistry | Year: 2012

In this paper, two new TPE-based conjugated molecules, constructed using tetraphenylethene (TPE) and carbazole or spirofluorene moieties, have been successfully prepared. They exhibited aggregation induced emission (AIE) properties, high thermal and morphological stabilities, and low oxidation potential, making them promising properties for optoelectric materials. The fabricated non-doped multilayer OLEDs demonstrate that devices using these luminophors as the emitting layer show relatively good performance, and the device of SFTPE gives a maximum luminance and efficiency of 8196 cd m -2 and 3.33 cd A -1, respectively, with the maximum emission wavelength at about 466 nm, thanks to the adjusted molecular structure and AIE characteristic of TPE. © 2012 The Royal Society of Chemistry.


Wu D.,Hubei University | Li Y.,Hubei University
Library and Information Science Research | Year: 2016

The Internet has become an important source of health information for elderly people in China. A controlled user experiment was conducted to understand how Chinese elderly people search for online health information. Twenty elderly people completed three search tasks based on three different health information seeking contexts. Online health information seeking behavior patterns of the elderly were found to include reselecting from results pages, following hyperlinks, and using a query reformulation patter. There was no significant difference with respect to emotion and the three task contexts, as elderly people have positive attitudes regarding the health information seeking process, but cognition within the three task contexts displayed significant differences. There was a significant correlation between education and Internet search proficiency regarding task search performance, while health condition, familiarity with the Internet and credibility of online health information were found to be primary factors that influenced the decision of the elderly to search for online health information. © 2016 Elsevier Inc.


Li J.,CAS Lanzhou Institute of Chemical Physics | Shi L.,CAS Lanzhou Institute of Chemical Physics | Chen Y.,CAS Lanzhou Institute of Chemical Physics | Zhang Y.,CAS Lanzhou Institute of Chemical Physics | And 5 more authors.
Journal of Materials Chemistry | Year: 2012

Stable superhydrophobic coatings were successfully achieved from thiol-ligand nanocrystals. Nanocrystals included VIII and IB metals and oxide nanoparticles, such as Fe, Co, Ni, Cu and Ag. We present a simple and available method that facilitates the synthesis of superhydrophobic textiles and sponges, in which the interaction between the nanocrystals and thiol plays a significant role in the formation of a special wetting surface. Meanwhile, the superhydrophobic textiles could also be endowed with new functionalities. For example, textiles with Fe 3O 4 nanocoatings possess magnetic properties, and Ag nanocrystals provide an antibacterial effect. If perfluoroalkyl thiol was used to replace alkyl thiol, the as-modified surfaces became oleophobic from superoleophilic. The proposed strategy was fit for various nanoparticles from as-established methods, including the preparation in different polar solvents, and the usage of surfactants as capping agents. As-prepared superhydrophobic nanocoatings show good durability towards hot water, surfactant aqueous solutions, and ultrasonic treatment in nonpolar solvents. The superhydrophobic and superoleophilic nanocoatings were effectively used for application in oil/water separation. © 2012 The Royal Society of Chemistry.


Jiang J.,Hubei University
International Journal of Simulation: Systems, Science and Technology | Year: 2016

A system based on Zigbee Technology is developed to solve the management problem of university laboratory. The overall framework and function modules of the system are studied in detail. The software and hardware of wireless data transmission node are designed. The functional tests met the requirements of the monitoring system. It achieved real-time speed in monitoring the laboratory safety and effectively improved the efficiency of the intelligently managing the open laboratory equipment. © 2016, UK Simulation Society. All rights reserved.


Hui F.,Hubei University
International Journal of Simulation: Systems, Science and Technology | Year: 2016

Research of complex network is widely conducted and applied in numerous fields. Its core issue is the relationship between nodes and edges, but its main direction is structural evolution, power distribution and propagation characteristics. In a dynamic complex environment, the change of the edge weight has the potential to be improved, the traditional consideration is the local characteristics, while it is difficult to achieve the goal of the overall optimization objectives. The white matter of the brain’s biological characteristics and complex network has many similarities, especially on axons myelin and edges weight. In this paper, we try to explore establishing an artificial white matter model of brain, and focus on the impact of the environment on complex networks. © 2016, UK Simulation Society. All rights reserved.


Zhu M.,Hubei University | Zou J.,South China University of Technology | Hu S.,South China University of Technology | Li C.,Hubei University | And 4 more authors.
Journal of Materials Chemistry | Year: 2012

New triphenylamine-based iridium(iii) dendritic complexes are demonstrated as active components for white polymer light-emitting diodes (WPLEDs). Initially the orange PLEDs are fabricated through dispersing the dendrimers into PVK in the presence of an electron-transport material 2-tert-butylphenyl-5-biphenyl-1, 3,4-oxadiazole (PBD). High performance of orange PLEDs is acquired by use of the low-conductivity anode buffer layer P8000, with the maximum current/power/external quantum efficiencies of 52.4 cd A -1/21.6 lm W -1/21.0%. Based on the excellent performance of the orange PLEDs, single-layer white polymer light-emitting devices (WPLEDs) are fabricated by double-doping sky-blue emitter iridium(iii) bis(2-(4,6-difluorophenyl)- pyridinato-N,C 2)picolinate (FIrpic) and the orange iridium dendrimers. These WPLEDs achieve the maximum current/power/external quantum efficiencies of 37.0 cd A -1/19.4 lm W -1/18.5%, which are among the highest efficiencies for dual-color WPLEDs ever reported. This work presents a premiere attempt on applying dendritic phosphor in highly efficient all-phosphor WPLEDs and a step forward to panchromatic application of Ir(iii) dendrimers. © 2012 The Royal Society of Chemistry.


Dang X.,Hubei University | Dang X.,Wuhan University | Hu H.,Wuhan University | Wang S.,Hubei University | Hu S.,Wuhan University
Microchimica Acta | Year: 2014

Electrochemical sensing has been demonstrated to represent an efficient way to quantify nitric oxide (NO) in challenging physiological environments. A sensing interface based on nanomaterials opens up new opportunities and broader prospects for electrochemical NO sensors. This review (with 141 refs.) gives a general view of recent advances in the development of electrochemical sensors based on nanomaterials. It is subdivided into sections on (i) carbon derived nanomaterials (such as carbon nanotubes, graphenes, fullerenes), (ii) metal nanoparticles (including gold, platinum and other metallic nanoparticles); (iii) semiconductor metal oxide nanomaterials (including the oxides of titanium, aluminum, iron, and ruthenium); and finally (iv) nanocomposites (such as those formed from carbon nanomaterials with nanoparticles of gold, platinum, NiO or TiO2). The various strategies are discussed, and the advances of using nanomaterials and the trends in NO sensor technology are outlooked in the final section. © 2014, Springer-Verlag Wien.


Zhao Q.P.,Hubei University | Zhao Q.P.,CAS Wuhan Institute of Hydrobiology | Jiang M.S.,Hubei University | Dong H.F.,Hubei University | Nie P.,CAS Wuhan Institute of Hydrobiology
PLoS Neglected Tropical Diseases | Year: 2012

Background: Schistosoma japonicum still causes severe parasitic disease in mainland China, but mainly in areas along the Yangtze River. However, the genetic diversity in populations of S. japonicum has not been well understood across its geographical distribution, and such data may provide insights into the epidemiology and possible control strategies for schistosomiasis. Methodology/Principal Findings: In this study infected Oncomelania snails were collected from areas in the middle and lower (ML) reaches of the Yangtze River, including Hubei, Hunan, Anhui, Jiangxi and Jiangsu provinces, and in the upper reaches of the river, including Sichuan and Yunnan provinces in southwest (SW) China. The adult parasites obtained from experimentally infected mice using isolated cercariae were sequenced individually for several fragments of mitochondrial regions, including Cytb-ND4L-ND4, 16S-12S and ND1. Populations in the ML reaches exhibited a relatively high level of diversity in nucleotides and haplotypes, whereas a low level was observed for populations in the SW, using either each single fragment or the combined sequence of the three fragments. Pairwise analyses of F-statistics (Fst) revealed a significant genetic difference between populations in the ML reaches and those in the SW, with limited gene flow and no shared haplotypes in between. It is rather obvious that genetic diversity in the populations of S. japonicum was significantly correlated with the geographical distance, and the geographical separation/isolation was considered to be the major factor accounting for the observed difference between populations in the ML reaches and those in the SW in China. Conclusions: S. japonicum in mainland China exhibits a high degree of genetic diversity, with a similar pattern of genetic diversity as observed in the intermediate host snails in the same region in China. © 2012 Zhao et al.


Li J.,Hong Kong Polytechnic University | Li J.,Hubei University | Yan F.,Hong Kong Polytechnic University
ACS Applied Materials and Interfaces | Year: 2014

High-performance low-voltage flash memories based on organic floating-gate field-effect transistors are prepared by a solution process for the first time. Transistors with a high-mobility n-type polymer semiconductor, poly{[N,N ′-bis(2-octyldodecyl)naphthalene-1,4,5,8-bis(dicarboximide)-2, 6-diyl]-alt-5,5′-(2,2′-bithiophene)}, and a high-k polymer gate dielectric, poly(vinylidene fluoride-trifluoroethylene-chlorofluoroethylene) (k ≈ 60), are successfully fabricated on flexible substrates. A thin layer of Au nanoparticles is embedded in the gate dielectric, which can store injected charge from the channel and result in a memory effect. The organic memories demonstrate high carrier mobilities (>0.3 cm2/(V s)), low program/erase voltages (±6 V), little degradation after 105 program/erase cycles, and good retention after 105 s, which suggest great promise in the application of nonvolatile memories in flexible electronics. © 2014 American Chemical Society.


Zou Y.,Hubei University | Ye T.,CAS Changchun Institute of Applied Chemistry | Ma D.,CAS Changchun Institute of Applied Chemistry | Qin J.,Hubei University | Yang C.,Hubei University
Journal of Materials Chemistry | Year: 2012

Two new hole-transporting materials, namely HFB-Cz and HFB-Dpa, were designed and synthesized by attaching carbazole and diphenylamine units to the hexakis(9,9-dihexyl-9H-fluoren-2-yl)benzene (HFB) core via Buchwald-Hartwig coupling reaction. The long alkyl chain and core rigidity endow these compounds with good solution processability and high thermal stability. HFB-Cz and HFB-Dpa exhibit significantly high glass transition temperatures (225 and 154 °C) relative to widely used hole-transporting materials, such as N,N′-bis(3-methylphenyl)-1,1′-biphenyl-4, 4′-diamine (TPD, 65 °C) and 1,4-bis((1-naphthylphenyl)amino)biphenyl (NPB, 96 °C). Solution-processed green OLED devices using HFB-Cz and HFB-Dpa as hole-transporting materials exhibit very high efficiencies with a maximum current efficiency up to 6.2 cd A-1. These efficiencies are substantially higher than the NPB-based control device, and are among the highest for the hole-transporting materials in similar device configuration. © The Royal Society of Chemistry 2012.


Li C.,Hubei University | Li H.,Hubei University
Pattern Recognition Letters | Year: 2012

It is well known that the naive Bayesian classifier assumes the attribute independence given the class. According to our observation, some distance functions also assume the attribute independence, such as Value Difference Metric (VDM). Short and Fukunaga Metric (SFM) is another widely used distance function, which does not assume the attribute independence. In this paper, we investigate the attribute independence assumption in VDM, and propose a Modified Short and Fukunaga Metric (MSFM) based on the attribute independence assumption. We find that MSFM is surprisingly similar to VDM. In fact, based on some assumptions, our MSFM can be regarded as a logarithmic modification of VDM. That is to say, in some sense, a logarithmic modification of SFM is equivalent to a logarithmic modification of VDM. Our experimental results on a large number of UCI benchmark datasets show that MSFM significantly outperforms SFM and SF2LOG (another improved version of SFM), and almost ties VDM. © 2012 Elsevier B.V. All rights reserved.


Zhu H.,Hubei University | Zhu H.,CAS Lanzhou Institute of Chemical Physics | Guo Z.,Hubei University | Guo Z.,CAS Lanzhou Institute of Chemical Physics | Liu W.,CAS Lanzhou Institute of Chemical Physics
Chemical Communications | Year: 2014

The adhesion behaviors of superhydrophobic surfaces have become an emerging topic to researchers in various fields as a vital step in the interactions between materials and organisms/materials. Controlling the chemical compositions and topological structures via various methods or technologies is essential to fabricate and modulate different adhesion properties, such as low-adhesion, high-adhesion and anisotropic adhesion on superhydrophobic surfaces. We summarize the recent developments in both natural superhydrophobic surfaces and artificial superhydrophobic surfaces with various adhesions and also pay attention to superhydrophobic surfaces switching between low- and high-adhesion. The methods to regulate or translate the adhesion of superhydrophobic surfaces can be considered from two perspectives. One is to control the chemical composition and change the surface geometric structure on the surfaces, respectively or simultaneously. The other is to provide external stimulations to induce transitions, which is the most common method for obtaining switchable adhesions. Additionally, adhesion behaviors on solid-solid interfaces, such as the behaviors of cells, bacteria, biomolecules and icing on superhydrophobic surfaces are also noticeable and controversial. This review is aimed at giving a brief and crucial overview of adhesion behaviors on superhydrophobic surfaces. © 2014 the Partner Organisations.


Liang F.,Kanazawa Medical University | Liang F.,Hubei University | Koya D.,Kanazawa Medical University
Diabetes, Obesity and Metabolism | Year: 2010

Insulin resistance (IR) is closely associated with obesity, type 2 diabetes mellitus (T2DM), hypertension, polycystic ovary syndrome (PCOS), non-alcohol fatty liver diseases (NAFLD) and metabolic syndrome and is also a risk factor for serious diseases such as cardiovascular diseases. Pharmacological treatments available for IR are limited by drug adverse effects. Because acupuncture has been practiced for thousands of years in China, it has been increasingly used worldwide for IR-related diseases. This review analyses 234 English publications listed on the PubMed database between 1979 and 2009 on the effectiveness of acupuncture as a treatment for IR. These publications provide clinical evidence, although limited, in support of the effectiveness of acupuncture in IR. At this stage, well-designed, evidence-based clinical randomized controlled trial studies are therefore needed to confirm the effects of acupuncture on IR. Numerous experimental studies have demonstrated that acupuncture can correct various metabolic disorders such as hyperglycemia, overweight, hyperphagia, hyperlipidemia, inflammation, altered activity of the sympathetic nervous system and insulin signal defect, all of which contribute to the development of IR. In addition, acupuncture has the potential to improve insulin sensitivity. The evidence has revealed the mechanisms responsible for the beneficial effects of acupuncture, though further investigations are warranted. © 2010 Blackwell Publishing Ltd.


This paper introduces the concept of green building and sustainable development as well as the relationship between them, combine with Weifang art and cultural center project, explains the design idea of green building and the concept of sustainable development, Finally, it proposes that only to coordinate the relationship among the construction, natural, human and society, can really achieve the green building which is sustainable development. © (2013) Trans Tech Publications, Switzerland.


This paper takes Weifang cultural arts center project total contract management as an example with the practice for total contract management mode of land replacement in order to present the background and problems of total contract management mode of land replacement and to investigate the management characteristics of total contract management mode of land replacement. The innovational management structure, management mechanism and basic management methods of total contract management mode of land replacement were proposed. These works have a good guide for reforming and improving the total contract management mode, behavior and system of land replacement. © (2013) Trans Tech Publications, Switzerland.


Liu F.X.,Hubei University
Zhonghua nan ke xue = National journal of andrology | Year: 2013

To explore the effect of seminal plasma lipoprotein (a) in abnormal semen liquefaction and its clinical significance. According to The WHO Laboratory Manual for the Examination and Processing of Human Semen, we conducted semen routine analyses of 101 patients with abnormal semen liquefaction and 26 normal healthy controls. We added chymotrypsin to the semen for 30 minutes of incubation at 37 degrees C. When there were filaments, we centrifuged the semen and obtained the upper seminal plasma to determine the level of lipoprotein (a). The level of lipoprotein (a) was significantly higher in the 101 patients ([526.2 +/- 243.5] mg/L) than in the 26 normal controls ([296.9 +/- 105.2] mg/L) (P < 0.01) . Lipoprotein (a) can inhibit fibrin dissolution, and delayed fibrin dissolution in semen liquefaction may be related to the increased level of seminal plasma lipoprotein (a). The seminal plasma lipoprotein (a) level should be taken into account in the clinical diagnosis of male infertility caused by abnormal semen liquefaction.


Xia L.,Hubei University | Li S.-L.,Hubei University | Ai X.-P.,Hubei University | Yang H.-X.,Hubei University | Cao Y.-L.,Hubei University
Energy and Environmental Science | Year: 2011

A novel temperature-sensitive cathode material, LiCoO 2@P3DT, exhibits not only improved cycling performance at ambient temperature, but also a thermal shutdown action at an elevated temperature of 110 °C, providing a self-activating thermal protection for lithium ion batteries. © 2011 The Royal Society of Chemistry.


Zhao L.M.,Nanyang Technological University | Tang D.Y.,Nanyang Technological University | Liu D.,Hubei University
Applied Physics B: Lasers and Optics | Year: 2010

Ultrahigh-repetition-rate (over 100 GHz) boundsoliton pulses were experimentally generated in a fiber laser. Through incorporating a Loyt-type filter made of a piece of high birefringent fiber and an intracavity polarizer in a fiber laser, we found that not only ultrahigh-repetition-rate single-pulse soliton but also bound-soliton trains could be generated. Numerical simulations confirm the experimental observations. © Springer-Verlag 2010.


Liu P.,Hubei University | Peng Z.H.,Hubei University
Applied Mechanics and Materials | Year: 2013

Virtual reality technology is a hot research topic in computer science and the introduction of virtual roaming to the field of urban planning provides a new means for urban design. This paper first analyzes the development, features and technology of virtual reality technology and the virtual city roaming and its applications and advantages in urban planning with focus on how to implement a virtual city roaming system by means of the scene development software Vega and finally concludes the importance of virtual city roaming in urban planning. © (2013) Trans Tech Publications, Switzerland.


Wang Y.,Hubei University
IEEE Technology and Society Magazine | Year: 2013

Ying Wang shares his views on Information ethics in reuse of public sector information (PSI) in China. Ying Wang examines the ethical status of statements made on Chinese public sector web sites with respect to the reuse of PSI using a case analysis approach to gain insight into the ethical considerations and legal risks. PSI is considered to have significant economic potential for thee country. The China Information Office of the State Council has published a report from 2006 titled, Notice about Division of Tasks of Strengthening Development and Utilization of Information Resources, which emphasized on encouraging social forces to reuse government information with economic and social value; formulating administrative measures to regulate reuse of government information. All of these reports point to the explicit need to channel development of information resources.


Wu S.,Hubei University
Zhongguo zhen jiu = Chinese acupuncture & moxibustion | Year: 2011

Based on the summarization of literatures on regulation of gastrointestinal electricity with acupuncture, the regulation effect of acupuncture, its influencing factors and its mechanism were analyzed in this article. It is found that the regulation effect can be influenced by many factors such as different acupuncture techniques, frequency, point selection, manipulations and the physical condition of the object. The effect of acupuncture appears great variety, which manifests as reinforced, inhibited or a kind of two-way regulation. And it is also held that the effect of acupuncture relies on the integrity of the nerve system. Nuclei, neurotransmitters, body fluid and gastrointestinal hormone also take part in the acupuncture effect. Therefore, studies on mechanism of acupuncture effect on gastrointestinal electricity should be strengthened in the future.


Huang X.-H.,Hubei University | Lu Y.,Hubei University | He Y.-B.,Hubei University | Chen Z.-H.,Hubei University
European Journal of Organic Chemistry | Year: 2010

We synthesized tetraazamacrocycles 1 and 2 bearing two anthryl groups as sidearms, both of which exhibited high selectivity for the Zn11 ion in switching-on-type responses in aqueous solution. For ligand 1, Zn 11 is coordinated by four nitrogen atoms of the macrocycle and two amino groups on the pendent arms, which results in proximity between the two fluorophores. So, 1-Zn11 shows obvious excimer emission in aqueous solution. When PPi or ATP was added (pH 7, 4), the excimer emission of 1-Zn 11 was quenched, whereas monomer emission was revived. To the best of our knowledge, no other known sensor has this characteristic under physiological pH conditions. At the same time, the obvious different fluorescence response of 1-Zn11 for PPi and ATP in water shows that receptor 1-Zn11 can be used as a selective fluorescent chemosensor for PPi and ATP anions. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.


To observe peripheral blood chromosome abnormality and microdeletions of the SRY and AZF genes on the Y chromosome in patients with chimera Klinefelter syndrome. We analyzed the cytogenetic karyotype of the peripheral blood chromosome in 1 infertile patient with mosaic karyotype Klinefelter syndrome and his parents. We identified 9 sequence tagged sites (STS) by multiplex PCR: sY84, sY86, sY127, sY129, sY134, sY254, sY255, sY242, and sY152. Meanwhile we detected the SRYgene and the microdeletion of AZF using ZFX/ZFY as the internal control gene. The karyotype of the patient was 46,XY (12%)/47,XXY (30%)/48,XXYY (56%)/49,XXXXY (2%). The karyotypes of his parents were normal. Consistency was found between the SRY gene and the chromosome gender in the patient and his parents. Y chromosome AZF microdeletion was observed in the patient. The deletion sites were sY86 and sY127, and the deletion type was AZFa + AZFb. AZF microdeletion of the Y chromosome exists in patients with Klinefelter syndrome. Chromosome karyotype and Y-chromosome AZF microdeletion are important criteria for the genetic diagnosis of Klinefelter syndrome.


Liu H.,Hubei University
Open Automation and Control Systems Journal | Year: 2014

We study the structure of cyclic codes of an arbitrary length n over the ring Fp + uFp + vFp, which is not a finite chain ring. We prove that the Gray image of a cyclic code over Fp + uFp + vFp is a 3-quasi-cyclic code over Fp. © Hualu Liu; Licensee Bentham Open.


Chen X.,Hubei University | Leung H.,University of Calgary | Tian M.,Hubei University
IEEE Transactions on Aerospace and Electronic Systems | Year: 2014

Through-the-wall radars (TWR) play an important role in various applications such as homeland security, search and rescue, and defense. One main challenge of performing automatic TWR data processing including detection and tracking is the strong reverberation and reflections from the walls. In the work presented here, we propose a practical and effective multiple target detection and tracking system for TWR. While background subtraction and envelope detection are used to reduce the false detected targets, an effective multiple target tracker is employed to further suppress the TWR false tracks. Using an experimental TWR, it is shown here that the proposed TWR data processing unit can effectively reduce false targets and false tracks and produce a good final surveillance picture for tracking human movement behind the walls. © 2014 IEEE.


Wan X.,Hubei University | Yia J.,Hubei University | Zhao Z.,Hubei University | Ke H.,Hubei University
IEEE Transactions on Aerospace and Electronic Systems | Year: 2014

China mobile multimedia broadcasting (CMMB) is a digital television standard that works in a single-frequency network (SFN) at the ultrahigh frequency band and adopts orthogonal frequency division multiplex modulation with a cyclic prefix (CP-OFDM). This paper investigates the practical feasibility of a CMMB-based passive radar (CPR) in the multipath propagation environment. First, several aspects involving system considerations induced by propagation conditions and radar signal characteristics are analyzed, including power budget, dynamic range requirement, clutter rejection metrics, and ambiguity function analysis. Then targeting the problems caused by multipath signals in the complex propagation environment and corresponding processing techniques are discussed, covering reference signal extraction and clutter rejection, as well as, tracking and localization. The highlight is clutter rejection with subcarrier-based spatial adaptive processing (SSAP), which is matched with the features of CP-OFDM. The applicability of SSAP under severe channel response spread mainly contributed by SFN is specially considered. Last, a description of the experiments and the CPR systems developed by Wuhan University is given, together with results from previous field trials for low-altitude aircraft and ship detection. © 1965-2011 IEEE.


Dai Y.,Hubei University | Ou L.,Hubei University | Liang W.,Hubei University | Yang F.,Hubei University | And 2 more authors.
Journal of Physical Chemistry C | Year: 2011

The commercial viability of polymer electrolyte membrane fuel cells in transportation applications will rely on significant reductions in the amount and great improvements in the stability of Pt in their cathodes to catalyze the oxygen reduction reaction (ORR). We demonstrated through first-principle theoretical calculations and experimental measurements that alloying Pt with 5d transition metal W could help to accomplish this aspiration. It was shown that the strong surface segregation tendency of Pt in Pt-W alloys and the peculiar electronic effect of W to Pt allow facile formation of stable Pt-enriched surfaces with likely better-than-Pt ORR activity at Pt-lean alloys such as PtW2, in contrast to the previously reported Pt alloy ORR electrocatalysts which mostly have to be Pt-rich in total composition (e.g., Pt3M). The prepared PtW2 alloy catalysts exhibited a Pt mass activity nearly 4 times higher than the pure Pt catalysts and almost no changes in the activity and surface area in over 30,000 cycles of potential cycling under oxidizing conditions of ORR, in contrast to significant losses seen with the pure Pt catalyst. In addition, the present study also showed a density functional theory-based multiple-descriptor strategy for screening durable and efficient bimetallic catalysts of low precious metal contents. © 2011 American Chemical Society.


Zhao Z.,Hubei University | Wan X.,Hubei University | Zhang D.,Hubei University | Cheng F.,Hubei University
IEEE Transactions on Antennas and Propagation | Year: 2013

This paper presents a description of recent research and development in HF passive bistatic radar (HFPBR) based on DRM digital AM broadcasting at Wuhan University, China. First, preliminary evaluation of its detection performance with special focus on the hybrid sky-surface wave propagation mode is introduced. Then, DRM broadcasting signal analysis as a radar waveform and associated signal processing techniques are described, consisting of ambiguity function analysis, reference signal extraction, multipath clutter rejection, and target localization. Finally, the experimental system and experimental data analysis are provided. Initial results from field experiments show that DRM-based HFPBR with hybrid sky-surface wave is a promising system for wide area moving target detection and ocean remote sensing. © 1963-2012 IEEE.


Sun Y.,Hubei University | Dai Y.,Hubei University | Liu Y.,Hubei University | Chen S.,Hubei University
Physical Chemistry Chemical Physics | Year: 2012

By using a catalyst-lean thin-film RDE method, the fast kinetics of the hydrogen oxidation reaction (HOR) on highly dispersed Pt nanoparticle electrocatalysts can be determined, free from the interference of the mass transport of H 2 molecules in solution. Measurements with carbon-supported Pt nanoparticles of different sizes thus allow revealing the particle size effect of Pt for the HOR. It is shown that there is a "negative" particle size effect of Pt on the kinetics of HOR, i.e., the exchange current density j 0 decreases with the increased dispersion (i.e. decreased mean particle size). A maximum mass activity of Pt for the HOR is found at particle sizes of 3-3.5 nm. The observed particle size effect is interpreted in terms of the size dependent distribution of surface atoms on the facets and edges, which is implied by the voltammetric responses of Pt/C catalysts with differently sized Pt particles. The accompanied decrease in the HOR activity with the increase in the edge atom fraction suggests that the edge atoms on the surface of Pt nanoparticles are less active for the HOR than those on the facets. © 2012 the Owner Societies.


Zhu M.,Hubei University | Ye T.,CAS Changchun Institute of Applied Chemistry | Li C.-G.,Hubei University | Cao X.,Hubei University | And 4 more authors.
Journal of Physical Chemistry C | Year: 2011

A series of fluorene-bridged anthracene derivatives appended with different charge transport moieties were synthesized, and their thermal, photophysical, and electrochemical properties were investigated. By the introduction of fluorene between two anthracene units as well as peripheral functional aryl substituents, the sophisticated compounds show a decreased tendency to crystallize and have high glass transition temperatures ranging from 165 to 229 °C. The theoretical calculations reveal that the four self-hosted blue emitters possess noncoplanar structure to suppress the intermolecular interaction in films. Solution-processed small-molecular organic light-emitting diodes featuring 1 as the emitter achieve a maximum current efficiency of 2.0 cd A-1 with Commisssion Internationale de L'Eclairage (CIE) coordinates of (0.15, 0.13), which are very close to the National Television Standards Committee's blue standard. A facile strategy to design solution-processable highly emissive anthracene derivatives for nondoped deep-blue electroluminescence by incorporating π-conjugated bridge and bipolar charge transport periphery is demonstrated. © 2011 American Chemical Society.


Qian J.,Hubei University | Zhou M.,Hubei University | Cao Y.,Hubei University | Ai X.,Hubei University | Yang H.,Hubei University
Journal of Physical Chemistry C | Year: 2010

Nanoembossed mesoporous LiFePO4 microspheres were first synthesized by a template-free hydrothermal process. These microspheres show a quite uniform size distribution of ∼3 μm and are composed of many densely aggregated ∼100 nm nanoparticles and interconnected nanochannels. This mesoporous structure can allow sucrose to penetrate into the spheres easily and generate a thorough carbon coating on the surface of the nanoparticles in the interior of the spheres. The composite materials' physical properties were further characterized by SEM, TEM, XRD, TG, BET surface area, and Raman spectroscopy. These microspheres as a cathode-active material show high tap density (1.4 g cm-3), excellent high rate capability (115 mAh g-1, 10 C), and cycling stability, possibly fulfilling the requirements of rechargeable lithium batteries for upcoming high power applications. © 2010 American Chemical Society.


Gong Y.,Hubei University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2015

Crowdsourcing has become an increasingly attractive practice for companies to execute business processes in open contexts with on-demand workforce and higher level of flexibility. One of the challenges is the identification of the best-fit crowdsourcing participant from a group of online candidates. This paper presents a method of AHP-TOPSIS based on Grey Relation Analysis for estimating participants of a crowdsourcing task based on their online profiles and proposals. This method is tested by an experiment on a dataset of 348 completed IT service crowdsourcing tasks. An analysis on the matching between the test result and the actual selection result reveals the accuracy and efficiency of this method. Companies can use this method to facilitate the quality control at the beginning of crowdsourcing and keeps the selection of participants easy. This paper contributes to the design of a software agent for crowdsourcing platforms to automatically rank the participants of a task. © IFIP International Federation for Information Processing 2015.


Ma Q.,Hubei University | Wang Y.,Hubei University
Journal of Medical Virology | Year: 2012

Escape mutations in the major hydrophilic region (MHR) of hepatitis B surface antigen (HBsAg) are reported widely worldwide; these mutations lead to diagnostic problems, emergence of vaccine-escape mutants, and hepatitis B immunoglobulin (HBIG) therapy failure. However, the prevalence of these mutations in different genotypes remains to be studied systematically. In the current study, 11,221 non-redundant hepatitis B virus (HBV) sequences of 8 genotypes (from A to H), obtained from the National Center for Biotechnology Information (NCBI), were analyzed to determine the prevalence of HBsAg escape mutations that were previously described. Eight important mutations associated with diagnostic failure, P120T, T126S, Q129H, G130N, S143L, D144A, and G145A/R, were prevalent in one or more genotypes, with the frequency of no less than 1%. With regard to escape variants that evade vaccine or immunoglobulin therapy, mutations were located mainly at positions 120, 126, 129, 130, 133, 134, 137, 140, 143, 144, and 145. The majority of such mutations showed genotypic heterogeneity, indicating the different distribution of the escape mutations. Most of the escape mutations clustered in the "a" determinant, indicating that this region was more likely to be affected by immune selection or antiviral therapy than other regions. Understanding the prevalence and heterogeneity of escape mutations could provide useful guidance for the improvement of diagnostic assays, design of new vaccines, and prevention of failure of HBIG therapy. © 2011 Wiley Periodicals, Inc.


Liu Q.,Hubei University | Zhang H.,Hubei University | Zhong H.,Hubei University | Zhang S.,Hubei University | Chen S.,Hubei University
Electrochimica Acta | Year: 2012

A non-precious metal electrocatalyst based on nitrogen-doped graphene (NG) was synthesized through a single step heat-treatment of a precursor mixture containing graphene oxide, urea, carbon black (CB) and small amount of iron species. The structure, morphology and composition of the prepared materials were characterized with a variety of techniques. XRD and Raman measurements showed the presence of distorted graphene layers. BET, TEM and cyclic voltammagram results indicated that CB served as spacer to prevent NG sheets from agglomerating, leading to enhanced dispersion of NG sheets. XPS analysis gave a total surface nitrogen concentration of ∼4 at.%, with the pyridinic nitrogen being the main component. Rotating electrode measurements revealed that the NG electrocatalyst can efficiently catalyze the oxygen reduction reaction (ORR), with activities equivalent to Pt/C in alkaline medium and approaching to Pt/C in acid medium, and with nearly 4-electron pathway selectivity. © 2012 Elsevier Ltd. All rights reserved.


Functional malignant pheochromocytoma is a rare tumor. Also, liver metastatic pheochromocytoma is deemed to be incurable because of its poor prognosis. Surgical debulking and removal of primary and metastases tumors, as well as radiosurgical or surgical treatment are recommended for patients. We treated a patient with multiple liver metastasis of functional malignant pheochromocytoma 4 years after the adrenal primary lesion was resected. The liver metastases were successfully removed by surgical resection. During the operation, the blood pressure increased quickly when the tumor was held between the fingers, reached the highest (201/110 mmHg), and then quickly declined to normal when the pressure was relieved. The patient is alive for more than 5 years after the operation. Thus, we believe that functional liver metastases of malignant pheochromocytoma may be curable by surgical resection with careful monitoring of anesthesia and blood pressure. Every effort should be taken to avoid direct stimulation of the tumor in the operation.


Fu J.,Hubei University | Zhang X.,Hubei University | Qian S.,Hubei University | Zhang L.,Hubei University
Talanta | Year: 2012

A united method for speciation analysis of Se (IV) and Se (VI) in environmental water samples was developed using nano-sized TiO 2 colloid as adsorbent and hydride generation atomic fluorescence spectrometry (HG-AFS) as determination means. When the pH values of bulk solution were between 6.0 and 7.0, successful adsorption onto 1 mL nano-sized TiO 2 colloid (0.2%) was achieved for more than 97.0% of Se (IV) while Se (VI) barely got adsorbed. Therefore, the method made it possible to preconcentrate and determine Se (IV) and Se (VI) separately. The precipitated TiO 2 with concentrated selenium was directly converted to colloid without desorption. Selenium in the resulting colloid was then determined by HG-AFS. The detection limits (3σ) and relative standard deviations (R.S.D) of this method were 24 ng/L and 42 ng/L, 7.8% (n = 6) and 7.0% (n = 6) for Se (IV) and Se (VI), respectively. This simple, sensitive, and united method was successfully applied to the separation and speciation of ultra-trace Se (IV) and Se (VI) in environmental water samples. © 2012 Elsevier B.V. All rights reserved.


Chen Z.-H.,Hubei University | Lu Y.,Hubei University | He Y.-B.,Hubei University | Huang X.-H.,Hubei University
Sensors and Actuators, B: Chemical | Year: 2010

A chiral compound 1 derived from bis(2-pyridinmethyl)amine was designed and synthesized, the dinuclear complexes 1-2Zn2+ and 1-2Cu2+ were formed through binding with metal ions (Zn2+, Cu2+). It was found that both complexes could be used to recognize anions in aqueous solution (10 mM HEPES buffer); pyrocatechol violet (PV) was used as the UV-vis indicator to monitor this binding process. Both ternary complexes 1-2Zn 2+ (PV) and 1-2Cu2+ (PV) displayed the selective recognition abilities towards pyrophosphate (PPi) anions much better than other anions such as phosphate (Pi), ATP, ADP, AMP, acetate and halogen anions. The binding results were further confirmed by the circular dichroism (CD) spectrum. © 2010 Elsevier B.V.


Zhou X.,Hubei University | Huang G.-R.,Hubei University | Hu P.,Hubei University
Molecules and Cells | Year: 2011

The Octamer 4 gene (Oct4) is a master pluripotency controller that has been detected in several types of tumors. Here, we examine the expression of Oct4 in human esophageal squamous cell carcinoma (ESCC). We found that punctate Oct4 protein was expressed in most (93.7%) ESCC samples but it was not observed in esophageal mucosa. Some ESCC cells had the capacity to form tumorospheres; those with an Oct4 +-rich cell phenotype had increased proliferation and Oct4 mRNA levels compared to t