Wuhan, China

The Huazhong University of Science and Technology is a public, coeducational research university located in Wuhan, Hubei province, China. As a national key university, HUST is directly affiliated to the Ministry of Education of China. HUST has been referred toas the flagship of China's higher education system after the Chinese Civil War. HUST manages Wuhan National Laboratories for Opto-electronics at Wuchang, which is one of the five national laboratories in China. Wikipedia.


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Patent
Huazhong University of Science and Technology | Date: 2014-06-20

A single-degree-of-freedom magnetic vibration isolation device belongs to vibration isolation devices and solves the following problems: the existing active and passive combined vibration reduction system is complex in structure, needs energy supply, and has low reliability. The present invention includes a metal conductor sleeve, a base, an upper annular permanent magnet, a lower annular permanent magnet, a connecting rod and a center permanent magnet; poles of the upper annular permanent magnet and the lower annular permanent magnet facing to each other have reverse polarity, which are connected to an upper end and a lower end of an inner wall of the metal conductor sleeve respectively; the center permanent magnet is concentrically sleeved on the connecting rod and fixedly connected therewith, and the center permanent magnet is located between the upper annular permanent magnet and the lower annular permanent magnet, and is capable of moving axially together with the connecting rod between the upper annular permanent magnet and the lower annular permanent magnet; and the pole of the center permanent magnet facing to the poles of the upper annular permanent magnet and the lower annular permanent magnet have reverse polarity. The present invention is simple in structure, does not need energy supply, has high reliability, and can generate a static magnetic force and a dynamic magnetic force. Connecting the device according to the present invention with a passive vibration isolation system in parallel can effectively improve the passive vibration isolation performance of the original system.


Patent
Huazhong University of Science and Technology | Date: 2015-06-12

The invention discloses a numerical control (NC) system based on a virtual host computer, the NC system comprising the virtual host computer arranged on a remote server, a local lower computer and a human-machine interactive device for human-machine interaction. The human-machine interactive device is used for providing a human-machine interactive input/output interface. The virtual host computer integrates a human-machine interactive module, a non-real-time/half-real-time task execution unit and a lower-computer control unit, and is used for receiving a NC machining instruction, processing the instruction to form a machine-tool control instruction through the non-real-time/half-real-time task execution unit, and transmitting the control data to the local lower computer through the lower-computer control unit by utilizing a network. The local lower computer controls a machine tool to execute real-time motion control and logic control. The NC system employs a new architecture formed by the upper computer and the lower computer by utilizing virtualization technology, and solves the restriction problems of data processing capability, HMI function expansion and remote machining of a conventional NC system.


Patent
Huazhong University of Science and Technology | Date: 2014-04-02

The present invention discloses an active airbearing device, including a airbearing body, a gas film active adjusting unit, a support body detection unit and a drive control unit, wherein the support body detection device measures a state of airbearing, the drive control system generates a control signal according to a detection signal, drives and controls the gas film active adjusting device to generate an active action, and dynamically adjusts the form of gas films on a airbearing surface, so as to dynamically adjust pressure distribution of gaps between the gas films of the airbearing device, thereby improving dynamic stiffness characteristics of the airbearing. Through the present invention, the dynamic stiffness characteristics of the airbearing can be improved significantly, and the purpose of stabilizing the airbearing is achieved; in addition, the active airbearing device according to the present invention also has the characteristics of a compact structure, convenient operation and control, and high precision, and thus is especially suitable for occasions such as ultra-precision machining or high speed spindle which has high requirements for dynamic stiffness of support.


Patent
Huazhong University of Science and Technology | Date: 2017-02-01

A multi-port DC-DC autotransformer, which is used for realizing interconnected transmission among a plurality of DC systems of different voltage levels. The autotransformer comprises 2N-1 current converters. The 2N-1 current converters are connected in series in sequence at a DC side and are connected to an AC line at an AC side, and the positive electrode of the ith current converter and the negative electrode of the (2N-i)th current converter of the 2N-1 current converters connected in series in sequence are respectively and correspondingly connected to the positive electrode and the negative electrode of the ith DC system, where N is the number of DC systems, and i is the serial number of the current converter. Further disclosed are a capacity design method for the current converters in the autotransformer and a control method for the autotransformer. The autotransformer enables most of the power transmitted among various DC systems to be directly transmitted through the electrical interconnection among the various DC systems without DC-AC-DC conversion, so that the rated voltage and the operating loss of the various current converters are greatly reduced, thereby reducing operating costs.


Patent
Huazhong University of Science and Technology | Date: 2017-01-04

A method for preparing a sericin hydrogel, the method including: 1) weighing a cocoon of a fibroin-deficient mutant silkworm, Bombyx mori, extracting the cocoon by an aqueous solution of LiBr or LiCl, dialyzing an extracted solution to yield a sericin solution having a concentration of a non-degraded sericin of between 0.1 and 4 wt. %; and 2) concentrating the sericin solution to a concentration of between 1.5 and 10 wt. %, adding a crosslinking agent to the concentrated sericin solution at a ratio of between 2 and 500 L of the crosslinking agent per each milliliter of the sericin solution, fully blending the crosslinking agent with the concentrated sericin solution, and keeping a resulting mixture at the temperature of between 4 and 45C for between 5 s and 36 hrs to yield a hydrogel.


Xue G.,Huazhong University of Science and Technology
Nature Nanotechnology | Year: 2017

Water evaporation is a ubiquitous natural process that harvests thermal energy from the ambient environment. It has previously been utilized in a number of applications including the synthesis of nanostructures and the creation of energy-harvesting devices. Here, we show that water evaporation from the surface of a variety of nanostructured carbon materials can be used to generate electricity. We find that evaporation from centimetre-sized carbon black sheets can reliably generate sustained voltages of up to 1 V under ambient conditions. The interaction between the water molecules and the carbon layers and moreover evaporation-induced water flow within the porous carbon sheets are thought to be key to the voltage generation. This approach to electricity generation is related to the traditional streaming potential, which relies on driving ionic solutions through narrow gaps, and the recently reported method of moving ionic solutions across graphene surfaces, but as it exploits the natural process of evaporation and uses cheap carbon black it could offer advantages in the development of practical devices. © 2017 Nature Publishing Group


News Article | May 5, 2017
Site: www.futurity.org

A new study uncovers an unexpected mechanism of glucose sensing in skeletal muscles that contributes to the body’s overall regulation of blood sugar levels. It’s well known that our taste buds can detect sugar. And after a meal, beta cells in the pancreas sense rising blood glucose and release the hormone insulin—which helps the sugar enter cells, where the body can use it for energy. “We found that skeletal muscle cells have machinery to directly sense glucose—in a certain sense it’s like the muscles can taste sugar, too,” says senior study author Jiandie Lin, a faculty member at the University of Michigan Life Sciences Institute. This ability of muscles to sense blood glucose is a separate and parallel process that augments the insulin-driven response. Together they work as a rheostat to maintain steady glucose levels in the body, particularly after a meal, according to findings published in the journal Molecular Cell. Continuing to develop an understanding of how the body self-regulates blood sugar at the molecular level could shed new light on obesity and diabetes, as well as point toward new therapeutic targets, says lead author Zhuoxian Meng, a research investigator in Lin’s lab. The researchers were able to examine the contributions of the glucose-sensing pathway in skeletal muscle by silencing a key gene—BAF60C—in cell cultures and in laboratory mice. “When we did that, the mice lacking BAF60C looked absolutely normal, but after we gave them a high-fat diet to induce obesity, they developed trouble disposing of the additional glucose after a meal,” Lin said. “The well-known insulin mechanism was not sufficient to process the glucose on its own.” Elevated blood sugar following a meal is a key symptom of type 2 diabetes. And chronic high blood sugar, also known hyperglycemia, can lead to serious health issues. “We found that the molecular pathway that’s engaged by glucose in muscle cells, at least the initial steps, is very similar to what happens in the beta cells in the pancreas,” says Lin, who is also a professor of cell and developmental biology at the University of Michigan Medical School. “This is very interesting because there’s a very important class of diabetes drugs known as sulfonylureas that act by closing a potassium channel and causing the beta cells to secrete more insulin. “Our research shows that this glucose-sensing pathway in muscle cells likely also plays a role in the drugs’ overall glucose-lowering action. The extent of the pathway’s contribution will need to be studied further.” Additionally, there are two steps within the glucose-sensing pathway that could serve as potential targets for modulation with therapeutic compounds. “It’s amazing how subtle changes in glucose can be detected throughout the body,” Lin says. “Beta cells respond, nerve cells respond, and now we know that muscle cells respond directly, too.” Other authors are from the University of Michigan and from Huazhong University of Science and Technology. The National Institutes of Health and the American Heart Association supported the work.


Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ICT-37-2016 | Award Amount: 2.56M | Year: 2017

Europe and China are at the forefront of technological advances in areas related to the Future Internet (especially 5G and IoT). While both parties share common technological objectives, there is still room for improvement in what concerns bilateral co-operation. As a result, the main purpose of EXCITING is to support the creation of favourable conditions for co-operation between the European and Chinese research and innovation ecosystems, mainly related to the key strategic domains of IoT and 5G. EXCITING will study the research and innovation ecosystem for IoT and 5G in China and compare it with the European model. EXCITING will identify and document the key international standards bodies for IoT and 5G, as well as other associations and fora where discussions take place and implementation decisions are made. Going beyond standardisation, interoperability testing is a key step towards market deployment. EXCITING will identify and document the key international InterOp events at which European and Chinese manufacturers can test and certify their IoT and 5G products. It will also explain the rules for engaging in these events. EXCITING will produce Best Practice guidelines for establishing and operating practical joint collaborations, in order to stimulate further such co-operations in the future on IoT and 5G Large Scale Pilots. As a result of the above investigations EXCITING will produce a roadmap showing how research and innovation ecosystems, policy, standardisation, interoperability testing and practical Large Scale Pilots should be addressed during the H2020 timeframe, and make recommendations for optimising collaboration between Europe and China for IoT and 5G.


Wang B.,Huazhong University of Science and Technology
ACM Computing Surveys | Year: 2011

Sensor networks, which consist of sensor nodes each capable of sensing environment and transmitting data, have lots of applications in battlefield surveillance, environmental monitoring, industrial diagnostics, etc. Coverage which is one of the most important performance metrics for sensor networks reflects how well a sensor field is monitored. Individual sensor coverage models are dependent on the sensing functions of different types of sensors, while network-wide sensing coverage is a collective performance measure for geographically distributed sensor nodes. This article surveys research progress made to address various coverage problems in sensor networks. We first provide discussions on sensor coverage models and design issues. The coverage problems in sensor networks can be classified into three categories according to the subject to be covered. We state the basic coverage problems in each category, and review representative solution approaches in the literature. We also provide comments and discussions on some extensions and variants of these basic coverage problems. © 2011 ACM.


Multiple transition metal functional groups including metaloxo, hydroxo, and hydroperoxide groups play significant roles in various biological and chemical oxidations such as electron transfer, oxygen transfer, and hydrogen abstraction. Further studies that clarify their oxidative relationships and the relationship between their reactivity and their physicochemical properties will expand our ability to predict the reactivity of the intermediate in different oxidative events. As a result researchers will be able to provide rational explanations of poorly understood oxidative phenomena and design selective oxidation catalysts. This Account summarizes results from recent studies of oxidative relationships among manganese(IV) molecules that include pairs of hydroxo/oxo ligands.Changes in the protonation state may simultaneously affect the net charge, the redox potential, the metal-oxygen bond order (M-O vs M-O), and the reactivity of the metal ion. In the manganese(IV) model system, [Mn IV(Me2EBC)(OH)2](PF6)2, the MnIV-OH and MnIV-O moieties have similar hydrogen abstraction capabilities, but MnIV-O abstracts hydrogen at a more than 40-fold faster rate than the corresponding MnIV-OH. However, after the first hydrogen abstraction, the reduction product, Mn III-OH2 from the MnIV-OH moiety, cannot transfer a subsequent OH group to the substrate radical. Instead the Mn III-OH from the MnIV-O moiety reforms the OH group, generating the hydroxylated product. In the oxygenation of substrates such as triarylphosphines, the reaction with the MnIV-O moiety proceeds by concerted oxygen atom transfer, but the reaction with the MnIV-OH functional group proceeds by electron transfer. In addition, the manganese(IV) species with a MnIV-OH group has a higher redox potential and demonstrates much more facile electron transfer than the one that has the MnIV-O group. Furthermore, an increase in the net charge of the MnIV-OH further accelerates its electron transfer rate. But its influence on hydrogen abstraction is minor because charge-promoted electron transfer does not enhance hydrogen abstraction remarkably. The Mn IV-OOH moiety with an identical coordination environment is a more powerful oxidant than the corresponding MnIV-OH and MnIV-O moieties in both hydrogen abstraction and oxygen atom transfer. With this full understanding of the oxidative reactivity of the MnIV-OH and Mn IV-O moieties, we have clarified the correlation between the physicochemical properties of these active intermediates, including net charge, redox potential, and metal-oxygen bond order, and their reactivities.The reactivity differences between the metal oxo and hydroxo moieties on these manganese(IV) functional groups after the first hydrogen abstraction have provided clues for understanding their occurrence and functions in metalloenzymes. The P450 enzymes require an iron(IV) oxo form rather than an iron(IV) hydroxo form to perform substrate hydroxylation. However, the lipoxygenases use an iron(III) hydroxo group to dioxygenate unsaturated fatty acids rather than an iron(III) oxo species, a moiety that could facilitate hydroxylation reactions. These distinctly different physicochemical properties and reactivities of the metal oxo and hydroxo moieties could provide clues to understand these elusive oxidation phenomena and provide the foundation for the rational design of novel oxidation catalysts. © 2012 American Chemical Society.

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