Samut Prakan, Thailand

Huachiew Chalermprakiet University

www.hcu.ac.th
Samut Prakan, Thailand

Huachiew Chalermprakiet University is a university located in Samut Prakan, Thailand. Huachiew Midwifery School, founded by the Poh Teck Tung Foundation, began offering nursing and midwifery training in 1941. It became Huachiew College with a single faculty in nursing in 1981 and expanded into a university in 1992 under its current name. The university today is organized into nine faculties and a graduate school. Wikipedia.


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Wilainam P.,Mahidol University | Nintasen R.,Huachiew Chalermprakiet University | Viriyavejakul P.,Mahidol University
Malaria Journal | Year: 2015

Background: Mast cells (MCs) play an important role in the immune response and inflammatory processes. Generally, MCs can be stimulated to degranulate and release histamine upon binding to immunoglobulin E (IgE). In malaria, MCs have been linked to immunoglobulin (Ig) E-anti-malarial antibodies. This study investigated the response of MCs in the skin of patients with Plasmodium falciparum malaria. Methods: Skin tissue samples were examined from ten uncomplicated and 20 complicated P. falciparum malaria cases. Normal skin tissues from 29 cases served as controls. Pre- and post-treatment tissues were included. Histopathological changes of the skin were evaluated using haematoxylin and eosin stain. MCs were investigated using toluidine blue staining. The percentage of MC degranulation was compared among groups and correlated with clinical data. Results: MC degranulation was significantly higher in the complicated P. falciparum (43.72% ± 1.44) group than the uncomplicated P. falciparum (31.35% ± 3.29) (p <0.05) and control groups (18.38% ± 1.75), (p <0.0001). MC degranulation correlated significantly with the degree of parasitaemia (rs = 0.66, p <0.0001). Associated pathological features, including extravasation of red blood cells, perivascular oedema and leukocyte infiltration were significantly increased in the malaria groups compared with the control group (all p <0.001). Conclusions: MCs in the skin dermis are activated during malaria infection, and the degree of MC degranulation correlates with parasitaemia and disease severity. © 2015 Wilainam et al.; licensee BioMed Central.


Techavuthiporn C.,Huachiew Chalermprakiet University | Boonyaritthongchai P.,King Mongkut's University of Technology Thonburi
Postharvest Biology and Technology | Year: 2016

The effects of prestorage short-term Anoxia treatment combined with modified atmosphere packaging (MAP) on quality changes during the storage of green asparagus (Asparagus officinalis L.) spears were investigated. Two sets of asparagus were used in this study. The first set underwent short-term Anoxia treatment via the administration of gaseous N2 for 8 h at room temperature, while the second set was kept in ambient air at the same temperature. Consequently, treated and untreated spears were stored either freely or packaged in plastic bags with low density polyethylene, in which a passive modification of the atmosphere was allowed to develop. All samples were stored at 4 °C for 8 days, followed by 8 days at 10 °C. Samples treated with neither Anoxia nor MAP were used as a control. Our results show that treating the asparagus samples with Anoxia and MAP (Anoxia + PE) caused lower respiration, slowing the decrease in headspace O2. In the Anoxia + PE treated samples, spears lost <12% fresh weight after 8 days at 10 °C. All treatments showed less increase in shear force while exposed at 4 °C for 8 days, as compared with the significant increase found when transferred to 10 °C. This increase in shear force was accompanied by the accumulation of fiber and lignin content. There was a positive relationship between toughening and fiber (R2 = 0.958) and toughening and lignin (R2 = 0.915). Moreover, the degradation of chlorophyll, sugar and ascorbic acid content under the Anoxia and MAP treatments were significantly reduced. The results of the present work indicate that Anoxia treatment, a non-chemical and simple postharvest technology, feasible for use in developing countries where food storage technologies are lacking. © 2016 Elsevier B.V.


Thongkanluang T.,Suratthani Rajabhat University | Chirakanphaisarn N.,Huachiew Chalermprakiet University
Key Engineering Materials | Year: 2016

Light green pigments based on Cr2O3, TiO2, Al2O3 and SiO2were prepared for reflective heat from solar radiation. The prepared pigment powders were mixed with ceramic glaze and sprayed onto ceramic substrates and then calcining accordance with ceramic processing for the reflectance measurement. The results show that the ceramic glaze 100 g mixed with the prepared pigment 5 g gives a maximum near infrared solar reflective of 70.94 %. The comparisons of performance test between prepared pigment and commercial green pigment that use for ceramic coating tile roof were covered two test boxes for temperature measurement. The results shown that the prepared pigment using make decrease the middle - room temperature less than commercial pigment using about 0.8 °C. It can be concluded that the prepared pigment is suitable to be used as a coating ceramic-based roofs for reducing the heat penetrating into the building. © 2016 Trans Tech Publications, Switzerland.


Wonganan O.,Ramkhamhaeng University | Tocharus C.,Chiang Mai University | Puedsing C.,Chiang Mai University | Homvisasevongsa S.,Huachiew Chalermprakiet University | And 2 more authors.
European Journal of Medicinal Chemistry | Year: 2013

Isosteviol (1) has been reported to exhibit moderate vasorelaxant activity. In order to enhance the bioactivity of this compound, chemical modification of 1 to the dihydro analog, ent-16β-hydroxybeyeran-19-oic acid (2), was undertaken. Compound 2 was then converted to the corresponding acetate derivative, ent-16β-acetoxybeyeran-19-oic acid (3). Biotransformation of compounds 1-3 by the fungus Cunninghamella echinulata NRRL 1386 was investigated and the metabolites 4-9 were obtained. The substrates and their metabolites were subjected to in vitro rat aorta relaxant activity evaluation. The metabolite 4, ent-7α-hydroxy-16-ketobeyeran-19-oic acid, exhibited the most highly potent activity, with EC50 of 3.46 nM, whereas the parent compound 1 showed relatively low activity (EC50 57.41 nM). A 17-fold increase in vasorelaxant activity of the analog 4 relative to compound 1 is of particular significant. Compound 4 exerted vasorelaxant activity at particularly low concentration and the vasorelaxant profile reached maximum at relatively low concentration, especially when compared with acetylcholine, the positive control. © 2012 Elsevier Masson SAS. All rights reserved.


Bamrungthai P.,Huachiew Chalermprakiet University | Puengsawad S.,Huachiew Chalermprakiet University
Proceedings 2015 International Conference on Science and Technology, TICST 2015 | Year: 2015

This paper presents an automatic people counting system for indoor environment. The system processes visual information obtained from an IP camera that is mounted in topview position above the door. The people detection process is designed to perform as a sequence of steps, including background subtraction, morphological operation, and blob detection. The results from the detection process are filtered and tracked to improve robustness of the system. A region-based approach is applied to the people counting process. The image obtained from the camera is divided into three regions and the counting algorithm is developed to track the people's state in the regions. The algorithm can count people with IN and OUT direction. Even when the system was setup without lighting control, the developed system can correctly count people as shown in the experiments. The output of the system can be exported to be used in downstream applications such as security surveillance and statistical analysis of customer behavior. © 2015 IEEE.


Bamrungthai P.,Huachiew Chalermprakiet University | Pleehachinda W.,Huachiew Chalermprakiet University
Proceedings 2015 International Conference on Science and Technology, TICST 2015 | Year: 2015

A game-based system to support stroke rehabilitation is developed in this paper. The goal is to make the rehabilitation process more accessible and enjoyable to the patients. The system consists of 3 modules, including the Device Module (DM), the Game Module (GM), and the Data Collection Module (DCM). The DM communicates with the Microsoft's Kinect device to receive the skeleton data of the patients and send it to the GM for the game processing. The jigsaw puzzle is implemented as a color matching game to simplify the gaming process and can support a wide range of patients. Hand and upper limb movement is required to grasp and move the jigsaw pieces to the right place. The trajectories of hand, elbow, and shoulder that are collected by the DCM can be used to assess the patient's progress. The system has been tested with a real patient. He can play the developed game after a learning period. The result shows that the body balance capability of the patient is implicitly required by the system to maintain motion tracking of the Kinect device. © 2015 IEEE.


Durongritichai V.,Huachiew Chalermprakiet University
Southeast Asian Journal of Tropical Medicine and Public Health | Year: 2012

The objectives of this study were to describe knowledge, attitudes, and self-awareness, and to identify predictable factors affecting HIV/AIDS prevention among Thai university students. A cross sectional survey was conducted among 844 first-year university students using a validated, self-administered questionnaire as a research instrument. The questionnaire included items assessing knowledge, attitudes, self-awareness, and HIV/AIDS preventive behaviors. It was found that 22.4% of the subjects received various sexually provocative media. The university student's knowledge, attitudes, self-awareness, and preventive behaviors toward HIV/AIDS were at a high level. The results from the multiple regression analysis identified self-awareness, faculty, sex, sexual-risk score, income-per-month, GPA, and knowledge as significant independent predictors of HIV/AIDS preventive behaviors. These factors contributed to 36.9% of the explanation of HIV preventive behaviors, and the strongest predictor was found to be self-awareness. Scientific information, and useful and productive life skills are needed to educate the university students regarding the health consequences of HIV/AIDS. An integrated approach is strongly suggested for creating knowledge, attitudes, and awareness to control the spread of HIV/AIDS among young people.


Kongmaroeng C.,Huachiew Chalermprakiet University | Kumkaen K.,Rayong Hospital
Tissue Antigens | Year: 2015

The FCGR3B gene encodes three human neutrophil antigens which consist of HNA-1a, HNA-1b, and HNA-1c. These antigens are encoded by three alleles in the FCGR3B locus: FCGR3B*01, FCGR3B*02, and FCGR3B*03 alleles, respectively. The frequencies of FCGR3B alleles have been reported in different ethnic populations. This study compared the FCGR3B gene frequencies among 230 unrelated healthy Eastern Thai blood donors in Rayong hospital with the previously published studies. The polymerase chain reaction-sequence-specific primers method was performed to determine FCGR3B genotypes. The results showed that the allele frequencies of FCGR3B*01, FCGR3B*02, and FCGR3B*03 were 0.722, 0.274, and 0.009, respectively. The FCGR3B*01 and FCGR3B*02 frequencies found in the Eastern Thais were similar to the previous reports investigating in Northern Thais, Chinese Han, Taiwanese, and Japanese populations. Interestingly, our data showed statistically significant difference (P<0.05) to Central Thais, Korean, Indian, Turkish, Australian, Tunisian, American, German, and Italian populations. In addition, one FCGR3Bnull, which represents a gene deletion, was also found in this study. This information is important not only for the assessment of neutrophil antibody-mediated clinical conditions and for disease association studies but also for anthropological studies. © 2015 John Wiley & Sons A/S.


Luxsuwong D.,Huachiew Chalermprakiet University | Indranupakorn R.,Huachiew Chalermprakiet University | Wongtrakul P.,Huachiew Chalermprakiet University
Journal of Oleo Science | Year: 2014

Lycopene, a lipophilic carotenoid, has been known as an effective antioxidant in supporting the cutaneous defensive system. However, it is unstable when exposed to light and water. In this study, lycopene was isolated from tomatoes and a vesicular delivery system was developed to entrap and stabilize the lycopene in the aqueous system. A simple process, maceration in ethyl acetate, was used to extract lycopene from the tomatoes. The extract was then chromatographed on the Sephadex LH20 column using acetone as a solvent system to yield 995 μg of lycopene per gram of dried tomato weight. The vesicular delivery system was prepared from a combination of ascorbic acid-6-palmitate (AP), cholesterol and dicetyl phosphate using a thin film hydration method. The formulation was composed of AP, cholesterol and dicetyl phosphate at a 44:44:12 molar ratio and with 2.12 μmol/ml of the isolated lycopene. Both blank vesicles and lycopene loaded vesicles were kept for a period of 3 months at 4±2°C and at the room temperature (28±2°C) to evaluate the effect of the encapsulation on the characteristic of the vesicles and on the antioxidant activity of the encapsulated lycopene. The result implied that lycopene could be stabilized in the vesicles and its scavenging activity against DPPH free radicals was superior to that of the free lycopene solution. © 2014 by Japan Oil Chemists' Society.


Chuprajob T.,Ramkhamhaeng University | Changtam C.,Huachiew Chalermprakiet University | Chokchaisiri R.,University of Phayao | Chunglok W.,Walailak University | And 2 more authors.
Bioorganic and Medicinal Chemistry Letters | Year: 2014

A general method for the synthesis of substituted (1E,4E,6E)-1,7- diphenylhepta-1,4,6-trien-3-ones, based on the aldol condensations of substituted 4-phenylbut-3-en-2-ones and substituted 3-phenylacrylaldehydes, was achieved. The natural trienones 4 and 5 have been synthesized by this method, together with the trienone analogues 9-20. These analogues were evaluated for their cytotoxic activity against human oral cancer KB cell line. The structure-activity relationship study has indicated that the analogues with the 1,4,6-trien-3-one function are more potent than the curcuminoid-type function. Analogues with meta-oxygen function on the aromatic rings are more potent than those in the ortho- and para-positions. Free phenolic hydroxy group is more potent than the corresponding methyl ether analogues. Among the potent trienones, compounds 11, 18 and 20 were more active than the anticancer drug ellipticine. All compounds were also evaluated against the non-cancerous Vero cells and it was found that compounds 11, 12 and 17 were much less toxic than curcumin (1); they showed high selectivity indices of 35.46, 33.46 and 31.68, respectively. These analogues are regarded as the potent trienones for anti-oral cancer study. © 2014 Elsevier Ltd. All rights reserved.

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