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Liao C.T.,Disaster Prevention & Water Environment Research Center | Yeh K.C.,Hsinchu | Liu G.H.,Hsinchu | Wu K.W.,Hsinchu
River Sedimentation - Proceedings of the 13th International Symposium on River Sedimentation, ISRS 2016 | Year: 2017

Characteristic motion of wash load is different from bed material load. In the past lots of studies assumed the wash load is 70∼90% of total suspended sediment in the river because of lacking data. It is difficult to define the grain size and proportion of wash load accurately by using this assumption; so sediment discharge could not be estimated precisely. The purpose of this study is developing a relationship of proportion of wash load with the influential factors in river. The relationship formula of wash load associated with suspended load is established by using the multivariate regression analysis with data collected on lower Kaoping River, Taiwan during the typhoon flood events. The effect of proportion of wash load on river deposition-erosion is carried out by using a 1-D mobile-bed model. Different inflow sediment concentrations associated with general empirical method and relationship formula of wash load are compared It can be known that the bed change simulated by the relationship formula from the observed values is superior to the result from general empirical method. In summary, the relationship formula of wash load provides not only an innovation method, but also some the subsequent applications. © 2017 Taylor & Francis Group, London.

Song W.T.,Hsinchu | Lin P.,Hsinchu
FTC 2016 - Proceedings of Future Technologies Conference | Year: 2016

An important performance measure for stochastic networks is so-called 'system reliability θ', defined as the probability that the output meets demand for rework-networks with n workstations, which have positive defective rates and random capacities Xi following a discrete distribution. Many analytical results in computing θ of stochastic networks widely exist in more than 18 related publications, but their papers' calculated values are incorrect. The most recent work - the Song rule - proposed in Song [19] indicated that 'in general, θ can not be expressed as 'Πn i=1P(Xi ≥ xi)' for some real values xi.' Motivated by the problem that the implementation of the Song rule used to solve for θ is time-consuming for networks with rework when n is large, we propose an extended Song rule to improve the computational efficiency. The computational efficiency for extended Song rule is increased by more than 90 percent of that for the Song rule in terms of CPU time for the two examples considered in this paper. The extended Song rule is a more analytical computational-efficient validator than the song rule of computing system reliability θ. © 2016 IEEE.

Lin C.-C.,Hsinchu | Huang M.-J.,Hsinchu | Chiu M.-J.,Hsinchu | Huang M.-P.,Hsinchu | And 8 more authors.
Chemistry of Materials | Year: 2017

Recently, thermally activated delayed fluorescence (TADF) materials have become the most promising hosts for realizing high-performance phosphorescent and fluorescent organic light-emitting diodes (OLEDs) because of their ability to upconvert triplet excitons to singlet excitons. However, despite a few TADF hosts having been introduced for low energy phosphorescent and fluorescent dopants, developing host materials with TADF properties for blue phosphorescent and TADF OLEDs is still a great challenge to date. In this study, bipolar hosts exhibiting TADF behavior and high triplet energy, consisting of the carbazole group as the donor, diphenylsulphone moiety as the acceptor, and m-bitolyl as the π-conjugated bridge, are synthesized and applied for the first time to blue devices. The ΔEST value of the TADF host is tuned via the introduction of a cyano group in the carbazole moiety due to the increase of the LE contribution in the CT excited state. Detailed photophysical studies confirm the efficient TADF properties of bipolar hosts. The blue phosphorescent and TADF devices using BT-01 as the host give external quantum efficiencies of 31.8% and 25.5%, respectively. The blue devices based on the BT-01 host exhibit superior electroluminescence performance and more reduced efficiency roll-off compared with those hosted by BT-02, ascribed to the faster reverse intersystem crossing process on the BT-01 host. These excellent results manifest that the use of the bipolar host with TADF behavior is a promising approach for the realization of highly efficient blue phosphorescent and TADF devices in the future. © 2017 American Chemical Society.

Yeh C.-C.,Hsinchu | Yeh C.-C.,Industrial Technology Research Institute of Taiwan | Wang P.-C.,Industrial Technology Research Institute of Taiwan | Pan Y.-H.,Industrial Technology Research Institute of Taiwan | And 3 more authors.
Proceedings - 2016 International Computer Symposium, ICS 2016 | Year: 2016

The citizen considers that data source collecting by the government can be released for more diversity usage. However, to archive the open data dream, sensitive data potentially could be published after the proper privacy preserving processing. In this paper, we present a scalable privacy preserving system for open/big data which leverages K-anonymity algorithm and Hadoop framework. We use an experiment data (i.e., 10 TB) to show our system can handle the high-volume data when increasing the system resource. It is an essential factor for the Government to publish the data with privacy preserving processing. © 2016 IEEE.

Yeh P.-H.,Hsinchu | Sun J.-S.,National Taiwan University Hospital | Wu H.-C.,Tatung University | Hwang L.-H.,National Yang Ming University | And 2 more authors.
RSC Advances | Year: 2013

In this study, an environmentally-sensitive hyaluronic acid (HA)-polyethylenimine (PEI) copolymer with disulfide linkage is synthesized, characterized and examined as a potential non-viral gene vector. From the results, a redox- and pH-sensitive gene delivery nanocarrier has been successfully synthesized via the analysis of 1H NMR and FT-IR. The positive HA-ss-PEI conjugate complexed with negatively charged plasmid DNA can be achieved via electrostatic attraction to form a stable spherical nanoparticle of 100 to 200 nm in diameter. N/P = 2 possesses the optimal condition for releasing encapsulated plasmid when triggered by stimuli such as redox reaction and pH change. The HA-ss-PEI/pEndo nanocarrier can transfect human mesenchymal stem cells to produce endostatin protein and these hMSCs are capable of differentiating into functional chondrocytes after 7 days chondrogenic induction. The nano-encapsulation of genetic anti-angiogenesis factor combined with the chondrogenic induction of hMSCs may offer an alternative choice and potentially effective administration strategy for arthritis. © The Royal Society of Chemistry 2013.

Wang H.,National Taipei University of Nursing and Health Sciences | Chung Y.,Hsinchu | Sun J.,Yuanpei University
Asian Pacific Journal of Cancer Prevention | Year: 2012

Aims: The purpose of this study was to investigate the effects of a breast cancer screening educational program on women's knowledge and intention to seek breast cancer screening in Taiwan. Materials and Method: This study describes the knowledge and intention of breast cancer screening changes during the period pre and post group education. A pre-test and post-test were used in both the experimental and the control groups. A convenience sampling was used. Two structured questionnaires were used. Results: The mean knowledge of breast cancer screening scores (pre-test and post-test) of the experimental group participants were 12.6 and 14.0. Then the mean knowledge of breast cancer screening scores (pre-test and post-test) of the control group participants were 11.8 and 12.1. The mean intention of breast cancer screening scores (pre-test and post-test) of the experimental group participants were 11.4 and 13.5. And the mean intention of breast cancer screening scores (pre-test and post-test) of the control group participants were 11.6 and 12.4. An independent-t test was applied to examine the differences among the two groups, revealing that the average post-test knowledge score differ significantly between the two groups (t =4.18, p<.00); and the post-test intention also demonstrate a marked statistical difference (t = 2.07, p<.05). A paired-t test was applied to examine the differences of each group, revealing that the total average scores of the experimental group participants on the knowledge of breast cancer screening scale clearly differ statistically (t =-5.54, p<.00); and the pre-test and post-test intention testing also demonstrate a marked statistical difference (t =-7.70, p<.00). Conclusions: These findings are helpful in understanding the knowledge and intention of breast cancer screening changes during the period pre and post group education. It is expected that these results can offer a reference for clinical breast cancer prevention.

Hsu L.-Y.,Chung Yuan Christian University | Yen W.-T.,Hsinchu
Chinese Journal of Physics | Year: 2010

We demonstrate why some quantum classical-secret sharing protocols using graph states cannot be secure. Based on our cryptanalysis, using the intercept-resend attack, a dishonest player can access the secret bit without any other's assistance and awareness. © 2010 THE PHYSICAL SOCIETY OF THE REPUBLIC OF CHINA.

Tsai P.-Y.,National Cheng Kung University | Huang H.-K.,National Cheng Kung University | Sung C.-M.,Hsinchu | Kan M.-C.,Hsinchu | Wang Y.-H.,National Cheng Kung University
Journal of Display Technology | Year: 2016

The thermal properties of a flip-chip light-emitting diode (FCLED) chip-on-board (COB) with diamond-like carbon (DLC) heat-spreading layers are investigated. The temperature-dependent performance of the COB packages with and without DLC heat-spreading layers at the LED and metal core printed circuit board sites are studied. Results show that the device junction temperature and thermal conductivity of the COB package with DLC heat-spreading layers (DLC package) are less than those of the COB package without DLC heat-spreading layers (regular package). For the steady state of light intensity, the mean of light intensity drop for 12 tested packages of DLC package was improved by 6.1% after 3 hours of burn-in compared with that of the regular package. © 2016 IEEE.

Kuo C.-H.,Hsinchu | Yang Y.-C.,Hsinchu | Gwo S.,Hsinchu | Gwo S.,National Tsing Hua University | Huang M.H.,Hsinchu
Journal of the American Chemical Society | Year: 2011

We report highly facet-dependent electrical properties of Cu2O nanocubes and octahedra and significant enhancement of gold nanocrystal cores to the electrical conductivity of Au-Cu2O core-shell octahedra. Cu 2O nanocubes and octahedra and Au-Cu2O coreshell cubes and octahedra were synthesized by following our reported facile procedures at room temperature. Two oxide-free tungsten probes attached to a nanomanipulator installed inside a scanning electron microscope made contacts to a single Cu2O nanocrystal for the I-V measurements. Pristine Cu2O octahedra bounded by {111} facets are 1100 times more conductive than pristine Cu2O cubes enclosed by {100} faces, which are barely conductive. Core-shell cubes are only slightly more conductive than pristine cubes. A 10 000-fold increase in conductivity over a cube has been recorded for an octahedron. Remarkably, core-shell octahedra are far more conductive than pristine octahedra. The same facet-dependent electrical behavior can still be observed on a single nanocrystal exposing both {111} and {100} facets. This new fundamental property may be observable in other semiconductor nanocrystals. We also have shown that both core-shell cubes and octahedra outperform pristine cubes and octahedra in the photodegradation of methyl orange. Efficient photoinduced charge separation is attributed to this enhanced photocatalytic activity. Interestingly, facet-selective etching occurred over the {100} corners of some octahedra and core-shell octahedra during photocatalysis. The successful preparation of Au-Cu2O core-shell heterostructures with precise shape control has offered opportunities to discover new and exciting physical and chemical properties of nanocrystals. © 2010 American Chemical Society.

Wu C.-H.,National Tsing Hua University | Lee H.,Hsinchu | Chen B.-S.,National Tsing Hua University
Bioinformatics | Year: 2011

Motivation: Synthetic biology aims to develop the artificial gene networks with desirable behaviors using systematic method. These networks with desired behaviors could be constructed using diverse biological parts, which may limit the development to complex synthetic gene networks. Fortunately, some well-characterized promoter libraries for engineering gene networks are widely available. Thus, a synthetic gene network can be constructed by selecting adequate promoters from promoter libraries to achieve the desired behaviors. However, the present promoter libraries cannot be directly applied to engineer a synthetic gene network. In order to efficiently select adequate promoters from promoter libraries for a synthetic gene network, promoter libraries are needed to be redefined based on the dynamic gene regulation.Results: Based on four design specifications, a library-based search method is proposed to efficiently select the most adequate promoter set from the redefined promoter libraries by a genetic algorithm (GA) to achieve optimal reference tracking design. As the number and size of promoter libraries increase, the proposed method can play an important role in the systematic design of synthetic biology. © The Author 2011. Published by Oxford University Press. All rights reserved.

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