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Rongo D.,HQ Inc
International Journal of Web Based Communities | Year: 2013

The natural phenomenon of the gathering of individuals has always provided an opportunity for social and economic research. In particular, studies examining company organisation emphasise the role of communities of practice in the transference of knowledge, enhancement of skills and coordination of employees. Business and economic researchers are now paying more attention to the potential use of this knowledge generated from accumulations of minds, in terms of innovating company production. This literature review offers an overview of the impact of ICT on the formation and functioning of these communities, with a focus on virtual communities of practice (vCoP). The innovative potential of vCoP in terms of New Product Development is examined. Several conceptual ideas to rationalise the online environment and avenues for further research are proposed. Copyright © 2013 Inderscience Enterprises Ltd. Source

Frazer R.S.,HQ Inc
Journal of the Royal Army Medical Corps | Year: 2010

The Triservice Anaesthetic Apparatus was designed around 30 years ago as a robust and highly portable anaesthesia delivery system for medical support to airborne operations and it has been the core anaesthesia system for the Defence Medical Services since then. Over this period there have been a number of equipment changes but issues remain which are in part mitigated by recent training developments. This article reviews these changes and developments and considers the future of this equipment. Source

Mustafa M.S.,Station Health Organisation Large | Rasotgi V.,AFMS Pensions | Jain S.,HQ Inc | Gupta V.,136 Station Health Organisation Large
Medical Journal Armed Forces India | Year: 2015

Dengue fever is a re-emerging public health problem with two-fifths of the world population being at risk of infection. Till now, dengue fever was believed to be caused by four different serotypes. The fifth variant DENV-5 has been isolated in October 2013. This serotype follows the sylvatic cycle unlike the other four serotypes which follow the human cycle. The likely cause of emergence of the new serotype could be genetic recombination, natural selection and genetic bottlenecks. There is no indication of the presence of DENV-5 in India. Recent clinical trials with the promising Chimerivax tetravalent vaccine suffered a setback. Discovery of DENV-5 and more such sylvatic strains in future may further impede the Dengue Vaccine Initiative. Integrated Vector Management holds the key to sustainable dengue control. Further epidemiological and ecological studies are needed to detect additional sylvatic dengue strains. © 2014, Armed Forces Medical Services (AFMS). All rights reserved. Source

Jacobsen T.B.,HQ Inc
Current Opinion in Psychiatry | Year: 2012

PURPOSE OF REVIEW: Involuntary treatment is burdened by the lack of evidence. One of the challenges is the difference in practice across borders in Europe. While reviewing the current literature, a proposal of monitoring guidelines is discussed. RECENT FINDINGS: The field is characterized by a small number of dedicated researchers. A study of violence in first-episode psychosis shows that differences in criteria for involuntary admission lead to different prognosis for the patients. The most recent contributions from the cross-national EUNOMIA study point to great variation across countries, regarding frequencies of involuntary admission as well as outcome. The EUNOMIA study provides suggestions for good quality in involuntary admission. A Cochrane review has examined the evidence of involuntary community treatment compared with standard treatment. The effectiveness of involuntary community treatment is limited. The review concludes that the benefits for a small number of patients are outweighed by the high numbers needed to treat in terms of avoided re-admission. SUMMARY: Despite pioneering work, involuntary treatment is still caught up in tradition. There is a lack of standard and proof of effectiveness. A proposal of monitoring guidelines for involuntary measures is a first step to improve the situation. © 2012 Wolters Kluwer Health | Lippincott Williams &Wilkins. Source

Bourinbaiar A.S.,HQ Inc | Jirathitikal V.,Immunitor Thailand Co.
Vaccine | Year: 2010

Modulation of the inflammatory response through vaccination has shown promise in animal models of atherogenesis and obesity-main risk factors for cardiovascular diseases. Tableted preparation, V-6, containing pooled antigens derived from pig adipose tissue was administered per os daily to 13 volunteers for 3 months. Total cholesterol and LDL levels have not changed from the baseline value; 193.4 vs 191.8 (p = 0.75) and 113.8 vs 117.2 (p = 0.18), respectively. Triglyceride levels declined by 26.1% from 163 to 120.5 mg/dL (p = 0.29). HDL increased by 25.9% from 38.6 to 48.5 mg/dL (p = 0.000002) in 12 out 13 patients. Despite negligible effect of V6 on weight and body mass index, i.e., 67.87 vs 66.58 kg (-1.9%; p = 0.46) and 26.25 vs 25.75 kg/m2 (-1.9%; p = 0.35), statistically significant reduction in waist (-7.6%; p = 0.002), mid-arm (-3.3%; p = 0.049), and thigh (-7.6%; p = 0.0003) circumferences were observed. Blood pressure systolic and diastolic values were not affected, i.e., 115.6 vs 121 (p = 0.2) and 77.1 vs 83 (p = 0.55). No changes were observed in liver ALT and AST enzymes. Creatinine decreased; 0.877 vs 0.842 mg/dL (p = 0.02), while BUN has shown slight increase; 14.8 vs 16.1 mg/dL (p = 0.03) but within normal range. Fasting blood sugar levels were also within normal range, i.e., 94.8 vs 98.8 (p = 0.04). Complete blood cell analysis has not revealed any change except slight decrease in hemoglobin 13.25-13.19 g/dL (p = 0.0004), but its amount per red blood cell (MCH) increased from 25.62 up to 26.42 picograms/cell (p = 0.000003). The average red blood cell size (MCV) increased from 78.5 to 80.0 fl (p = 0.00009) but hemoglobin concentration relative to size of the cell (MCHC) has not changed (p = 0.2). Hematocrit and red blood cells count decreased slightly, but within normal range 40.7-40.2% (p = 0.02) and 5.22-5.05 × 106 cells/mm3 (p = 0.002). The number of platelets moved upward, 2.471 vs 2.921 × 105 per mm3 (p = 0.009). The white blood cells count and percent of leukocytes and neutrophils were not affected. Pro-inflammatory eosinophils declined from 4.0% down to 2.4% (p = 0.29). These results show that V6 is safe and holds a promise as an anti-atherogenic and overweight/obesity immune intervention. © 2010 Elsevier Ltd. All rights reserved. Source

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